Published in J Biol Chem on June 04, 2001
Mechanisms of necroptosis in T cells. J Exp Med (2011) 2.51
Antigen-mediated T cell expansion regulated by parallel pathways of death. Proc Natl Acad Sci U S A (2008) 2.20
RIPK-dependent necrosis and its regulation by caspases: a mystery in five acts. Mol Cell (2011) 2.06
It cuts both ways: reconciling the dual roles of caspase 8 in cell death and survival. Nat Rev Mol Cell Biol (2011) 1.76
Fas-associated death domain (FADD) is a negative regulator of T-cell receptor-mediated necroptosis. Proc Natl Acad Sci U S A (2010) 1.67
Cellular FLICE-inhibitory protein is required for T cell survival and cycling. J Exp Med (2005) 1.52
Phosphorylated FADD induces NF-kappaB, perturbs cell cycle, and is associated with poor outcome in lung adenocarcinomas. Proc Natl Acad Sci U S A (2005) 1.44
Distinct transcriptional programs in thymocytes responding to T cell receptor, Notch, and positive selection signals. Proc Natl Acad Sci U S A (2004) 1.42
Fas-associated death domain protein interacts with methyl-CpG binding domain protein 4: a potential link between genome surveillance and apoptosis. Proc Natl Acad Sci U S A (2003) 1.29
Investigation of the immunosuppressive activity of artemether on T-cell activation and proliferation. Br J Pharmacol (2007) 1.08
Intertwined pathways of programmed cell death in immunity. Immunol Rev (2010) 1.04
The "fuzzy logic" of the death-inducing signaling complex in lymphocytes. J Clin Immunol (2003) 0.96
Phosphorylation of FADD by the kinase CK1α promotes KRASG12D-induced lung cancer. Sci Signal (2015) 0.93
Regulation of lymphocyte progenitor survival by the proapoptotic activities of Bim and Bid. Proc Natl Acad Sci U S A (2008) 0.92
Regulation of protein kinase C inactivation by Fas-associated protein with death domain. J Biol Chem (2012) 0.92
New roles for old enzymes: killer caspases as the engine of cell behavior changes. Front Physiol (2014) 0.89
Inhibition of Fas-associated death domain-containing protein (FADD) protects against myocardial ischemia/reperfusion injury in a heart failure mouse model. PLoS One (2013) 0.86
FADD adaptor in cancer. Med Immunol (2005) 0.84
Caspase-3 is transiently activated without cell death during early antigen driven expansion of CD8(+) T cells in vivo. PLoS One (2010) 0.81
A novel kinase inhibitor of FADD phosphorylation chemosensitizes through the inhibition of NF-κB. Mol Cancer Ther (2011) 0.80
Mammalian nitrilase 1 homologue Nit1 is a negative regulator in T cells. Int Immunol (2009) 0.78
Abelson virus transformation prevents TRAIL expression by inhibiting FoxO3a and NF-kappaB. Mol Cells (2010) 0.78
Fgf regulates dedifferentiation during skeletal muscle regeneration in adult zebrafish. Cell Signal (2016) 0.77
DED or alive: assembly and regulation of the death effector domain complexes. Cell Death Dis (2015) 0.77
Apoptotic potential of Fas-associated death domain on regulation of cell death regulatory protein cFLIP and death receptor mediated apoptosis in HEK 293T cells. J Cell Commun Signal (2012) 0.76
Autophagy regulates cytoplasmic remodeling during cell reprogramming in a zebrafish model of muscle regeneration. Autophagy (2016) 0.76
FADD regulates thymocyte development at the β-selection checkpoint by modulating Notch signaling. Cell Death Dis (2014) 0.75
MiR-7a is an important mediator in Fas-associated protein with death domain (FADD)-regulated expression of focal adhesion kinase (FAK). Oncotarget (2016) 0.75
Fas-associated protein with death domain (FADD) regulates autophagy through promoting the expression of Ras homolog enriched in brain (Rheb) in human breast adenocarcinoma cells. Oncotarget (2016) 0.75
Deregulated FADD expression and phosphorylation in T-cell lymphoblastic lymphoma. Oncotarget (2016) 0.75
RIPK3/Fas-Associated Death Domain Axis Regulates Pulmonary Immunopathology to Cryptococcal Infection Independent of Necroptosis. Front Immunol (2017) 0.75
Intrinsically disordered protein. J Mol Graph Model (2001) 8.54
Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1. Nature (1998) 4.97
Clusters of genes encoding mouse transplantation antigens. Cell (1982) 4.71
Expression of a retinoic acid response element-hsplacZ transgene defines specific domains of transcriptional activity during mouse embryogenesis. Genes Dev (1991) 3.79
CTLA-4-Mediated inhibition of early events of T cell proliferation. J Immunol (1999) 3.49
The murine T-cell receptor uses a limited repertoire of expressed V beta gene segments. Nature (1985) 3.36
Cloning of GT box-binding proteins: a novel Sp1 multigene family regulating T-cell receptor gene expression. Mol Cell Biol (1992) 3.10
Predominant use of a V alpha gene segment in mouse T-cell receptors for cytochrome c. Nature (1987) 2.99
Studies on SP6 promoter using a new plasmid vector that allows gene insertion at the transcription initiation site. Nucleic Acids Res (1987) 2.79
Requirement for the orphan steroid receptor Nur77 in apoptosis of T-cell hybridomas. Nature (1994) 2.78
Notch activity influences the alphabeta versus gammadelta T cell lineage decision. Cell (1997) 2.66
Separate elements control DJ and VDJ rearrangement in a transgenic recombination substrate. EMBO J (1990) 2.52
An activated form of Notch influences the choice between CD4 and CD8 T cell lineages. Cell (1996) 2.42
Genomic organization of the genes encoding mouse T-cell receptor alpha-chain. Nature (1985) 2.40
A role for the orphan steroid receptor Nur77 in apoptosis accompanying antigen-induced negative selection. Immunity (1995) 2.31
Direct assessment of MHC class I binding by seven Ly49 inhibitory NK cell receptors. Immunity (1999) 2.18
Early postnatal development of corpus callosum and corticospinal white matter assessed with quantitative tractography. AJNR Am J Neuroradiol (2007) 2.11
Functional redundancy of the Nur77 and Nor-1 orphan steroid receptors in T-cell apoptosis. EMBO J (1997) 2.09
ERK5 is a novel type of mitogen-activated protein kinase containing a transcriptional activation domain. Mol Cell Biol (2000) 2.02
The influence of a polymorphism at position -857 of the tumour necrosis factor alpha gene on clinical response to etanercept therapy in rheumatoid arthritis. Rheumatology (Oxford) (2005) 1.96
Genetic mapping in the major histocompatibility complex by restriction enzyme site polymorphisms: most mouse class I genes map to the Tla complex. Proc Natl Acad Sci U S A (1983) 1.96
Identification of human and mouse p19, a novel CDK4 and CDK6 inhibitor with homology to p16ink4. Mol Cell Biol (1995) 1.84
Crystal structure of human mitochondrial single-stranded DNA binding protein at 2.4 A resolution. Nat Struct Biol (1997) 1.76
Detection of resistance to isoniazid, rifampin, and streptomycin in clinical isolates of Mycobacterium tuberculosis by molecular methods. Clin Infect Dis (1997) 1.76
Cloning of murine TCF-1, a T cell-specific transcription factor interacting with functional motifs in the CD3-epsilon and T cell receptor alpha enhancers. J Exp Med (1991) 1.69
Thymocyte development is normal in CTLA-4-deficient mice. Proc Natl Acad Sci U S A (1997) 1.67
Regulation of the Nur77 orphan steroid receptor in activation-induced apoptosis. Mol Cell Biol (1995) 1.65
A mouse Fas-associated protein with homology to the human Mort1/FADD protein is essential for Fas-induced apoptosis. Mol Cell Biol (1996) 1.62
Downregulation of Wnt2 and beta-catenin by siRNA suppresses malignant glioma cell growth. Cancer Gene Ther (2008) 1.61
Influenza surveillance in Korea: establishment and first results of an epidemiological and virological surveillance scheme. Epidemiol Infect (2007) 1.60
Molecular characterization of the recombination region of six murine major histocompatibility complex (MHC) I-region recombinants. J Mol Cell Immunol (1984) 1.60
Absence of the mid-sized neurofilament subunit decreases axonal calibers, levels of light neurofilament (NF-L), and neurofilament content. J Cell Biol (1998) 1.51
FADD is required for DR4- and DR5-mediated apoptosis: lack of trail-induced apoptosis in FADD-deficient mouse embryonic fibroblasts. J Biol Chem (2000) 1.51
Proposal for genetic characterisation of wild-type mumps strains: preliminary standardisation of the nomenclature. Arch Virol (2005) 1.45
Selection is not required to produce invariant T-cell receptor gamma-gene junctional sequences. Nature (1993) 1.45
A locus control region in the T cell receptor alpha/delta locus. Immunity (1994) 1.37
T cell-specific FADD-deficient mice: FADD is required for early T cell development. Proc Natl Acad Sci U S A (2001) 1.33
Requirement of heavy neurofilament subunit in the development of axons with large calibers. J Cell Biol (1998) 1.32
The human enhancer-binding protein Gata3 binds to several T-cell receptor regulatory elements. Proc Natl Acad Sci U S A (1991) 1.32
Identification and characterization of a human cDNA homologous to yeast SKI2. Genomics (1995) 1.27
Detection of c-sis transcripts and synthesis of PDGF-like proteins by human osteosarcoma cells. Science (1984) 1.26
NK cell expression of the killer cell lectin-like receptor G1 (KLRG1), the mouse homolog of MAFA, is modulated by MHC class I molecules. Eur J Immunol (2000) 1.21
Inhibition of Fas-mediated apoptosis by the B cell antigen receptor through c-FLIP. Eur J Immunol (2000) 1.21
Modulation of the redox potential of the [Fe(SCys)(4)] site in rubredoxin by the orientation of a peptide dipole. Biochemistry (1999) 1.19
Transgenic expression of the Ly49A natural killer cell receptor confers class I major histocompatibility complex (MHC)-specific inhibition and prevents bone marrow allograft rejection. J Exp Med (1996) 1.18
Start site selection at lacUV5 promoter affected by the sequence context around the initiation sites. Nucleic Acids Res (1994) 1.17
A large-scale gene-trap screen for insertional mutations in developmentally regulated genes in mice. Genetics (1995) 1.14
T cell receptor DJ but not VDJ rearrangement within a recombination substrate introduced into a pre-B cell line. Int Immunol (1989) 1.13
Leucine 41 is a gate for water entry in the reduction of Clostridium pasteurianum rubredoxin. Protein Sci (2001) 1.12
Insulin-like growth factor-1 protects H9c2 cardiac myoblasts from oxidative stress-induced apoptosis via phosphatidylinositol 3-kinase and extracellular signal-regulated kinase pathways. Life Sci (2001) 1.12
Effects of ipt gene expression on the physiological and chemical characteristics of Artemisia annua L. Plant Sci (2001) 1.12
A common core for binding single-stranded DNA: structural comparison of the single-stranded DNA-binding proteins (SSB) from E. coli and human mitochondria. FEBS Lett (1997) 1.10
Feeding practices in 105 counties of rural China. Child Care Health Dev (2005) 1.07
Effects of saturation mutagenesis of the phage SP6 promoter on transcription activity, presented by activity logos. Proc Natl Acad Sci U S A (2000) 1.05
A role for the cytoplasmic tail of the beta chain of CD8 in thymic selection. Immunity (1994) 1.05
The developmental fate of T cells is critically influenced by TCRgammadelta expression. Immunity (1998) 1.04
Adjacent DNA elements dominantly restrict the ubiquitous activity of a novel chromatin-opening region to specific tissues. EMBO J (1997) 1.04
DNA sequencing and genotyping by transcriptional synthesis of chain-terminated RNA ladders and MALDI-TOF mass spectrometry. Nucleic Acids Res (2001) 1.04
Structure of human cyclin-dependent kinase inhibitor p19INK4d: comparison to known ankyrin-repeat-containing structures and implications for the dysfunction of tumor suppressor p16INK4a. Structure (1998) 1.02
Nur77 transcription activity correlates with its apoptotic function in vivo. Eur J Immunol (1999) 1.01
Genetic studies of systemic lupus erythematosus in Asia: where are we now? Genes Immun (2009) 1.00
Developmentally programmed rearrangement of T cell receptor Vgamma genes is controlled by sequences immediately upstream of the Vgamma genes. Immunity (1998) 1.00
Genetic polymorphisms of OPG, RANK, and ESR1 and bone mineral density in Korean postmenopausal women. Calcif Tissue Int (2005) 0.99
Phylogenetic analysis of the nef gene reveals a distinctive monophyletic clade in Korean HIV-1 cases. J Acquir Immune Defic Syndr Hum Retrovirol (1998) 0.97
The role of short homology repeats and TdT in generation of the invariant gamma delta antigen receptor repertoire in the fetal thymus. Immunity (1995) 0.96
The number of identical kringle IV repeats in apolipoprotein(a) affects its processing and secretion by HepG2 cells. J Biol Chem (1996) 0.96
Mice lacking Dad1, the defender against apoptotic death-1, express abnormal N-linked glycoproteins and undergo increased embryonic apoptosis. Dev Biol (2000) 0.95
High isolation rate of adenovirus serotype 7 from South Korean military recruits with mild acute respiratory disease. Eur J Clin Microbiol Infect Dis (2007) 0.95
Pathogenicity and antigenicity of a new influenza A (H5N1) virus isolated from duck meat. J Med Virol (2003) 0.95
Loss of TRAIL-R does not affect thymic or intestinal tumor development in p53 and adenomatous polyposis coli mutant mice. Cell Death Differ (2005) 0.94
Control of organ-specific demethylation by an element of the T-cell receptor-alpha locus control region. J Biol Chem (2000) 0.94
Two enhancer regions in the mouse En-2 locus direct expression to the mid/hindbrain region and mandibular myoblasts. Development (1993) 0.94
GATA-3 dominant negative mutant. Functional redundancy of the T cell receptor alpha and beta enhancers. J Biol Chem (1995) 0.94
A regulatory SNP at position -899 in CDKN1A is associated with systemic lupus erythematosus and lupus nephritis. Genes Immun (2009) 0.93
Control of VDJ recombinase activity. Cold Spring Harb Symp Quant Biol (1989) 0.92
Extension of the four-stranded intercalated cytosine motif by adenine.adenine base pairing in the crystal structure of d(CCCAAT). Nat Struct Biol (1995) 0.92
Bipartite modular structure of intrinsic, RNA hairpin-independent termination signal for phage RNA polymerases. J Biol Chem (1999) 0.90
The class II genes of the rat MHC. J Immunol (1989) 0.89
A new element within the T-cell receptor alpha locus required for tissue-specific locus control region activity. Mol Cell Biol (1999) 0.89
Function and factor interactions of a locus control region element in the mouse T cell receptor-alpha/Dad1 gene locus. J Immunol (2001) 0.89
A targeted mutation at the T-cell receptor alpha/delta locus impairs T-cell development and reveals the presence of the nearby antiapoptosis gene Dad1. Mol Cell Biol (1997) 0.89
Receptor-mediated apoptosis in T lymphocytes. Cold Spring Harb Symp Quant Biol (1999) 0.89
Identification and cloning of the G3B cDNA encoding a 3' segment of a protein binding to GATA-3. Gene (1995) 0.88
Single-stranded RNA recognition by the bacteriophage T4 translational repressor, regA. J Biol Chem (1997) 0.88
Sequence-specific termination by T7 RNA polymerase requires formation of paused conformation prior to the point of RNA release. Genes Cells (2001) 0.88
Soluble expression of cloned phage K11 RNA polymerase gene in Escherichia coli at a low temperature. Protein Expr Purif (1999) 0.88