Published in Development on June 01, 2001
A transcription factor-based mechanism for mouse heterochromatin formation. Nat Struct Mol Biol (2012) 2.15
Sequential actions of Pax3 and Pax7 drive xanthophore development in zebrafish neural crest. Dev Biol (2008) 1.55
Integrated functions of Pax3 and Pax7 in the regulation of proliferation, cell size and myogenic differentiation. PLoS One (2009) 1.15
Dynamic alterations in gene expression after Wnt-mediated induction of avian neural crest. Mol Biol Cell (2005) 1.03
Pax3 is essential for normal cardiac neural crest morphogenesis but is not required during migration nor outflow tract septation. Dev Biol (2011) 0.99
Cloning of zebrafish nkx6.2 and a comprehensive analysis of the conserved transcriptional response to Hedgehog/Gli signaling in the zebrafish neural tube. Gene Expr Patterns (2007) 0.96
How to form and close the brain: insight into the mechanism of cranial neural tube closure in mammals. Cell Mol Life Sci (2012) 0.92
β-catenin regulates Pax3 and Cdx2 for caudal neural tube closure and elongation. Development (2013) 0.87
Noggin and basic FGF were implicated in forebrain fate and caudal fate, respectively, of the neural tube-like structures emerging in mouse ES cell culture. Exp Brain Res (2005) 0.86
Activation of Pax3 target genes is necessary but not sufficient for neurogenesis in the ophthalmic trigeminal placode. Dev Biol (2008) 0.84
Combinatorial transcriptional interaction within the cardiac neural crest: a pair of HANDs in heart formation. Birth Defects Res C Embryo Today (2004) 0.81
Gene array analysis of neural crest cells identifies transcription factors necessary for direct conversion of embryonic fibroblasts into neural crest cells. Biol Open (2016) 0.75
Endoglin is required in Pax3-derived cells for embryonic blood vessel formation. Dev Biol (2015) 0.75
Multiple point mutations affecting the simian virus 40 enhancer. Science (1983) 13.69
Simian virus 40 tandem repeated sequences as an element of the early promoter. Proc Natl Acad Sci U S A (1981) 13.67
Host-specific activation of transcription by tandem repeats from simian virus 40 and Moloney murine sarcoma virus. Proc Natl Acad Sci U S A (1982) 12.30
Enhancer elements. Cell (1983) 10.41
Pax7 is required for the specification of myogenic satellite cells. Cell (2000) 9.88
Characterization of enhancer elements in the long terminal repeat of Moloney murine sarcoma virus. J Virol (1984) 7.80
Specific interaction between enhancer-containing molecules and cellular components. Cell (1984) 6.96
Participation of p53 cellular tumour antigen in transformation of normal embryonic cells. Nature (1985) 6.86
Development of peripheral lymphoid organs and natural killer cells depends on the helix-loop-helix inhibitor Id2. Nature (1999) 6.23
Activation of SV40 genome by 72-base pair tandem repeats of Moloney sarcoma virus. Nature (1982) 6.02
Temporal control of gene expression in transgenic mice by a tetracycline-responsive promoter. Proc Natl Acad Sci U S A (1994) 5.71
New type of POU domain in germ line-specific protein Oct-4. Nature (1990) 5.65
Pax-6, a murine paired box gene, is expressed in the developing CNS. Development (1991) 5.49
Lack of beta-catenin affects mouse development at gastrulation. Development (1995) 4.95
Cre-mediated gene deletion in the mammary gland. Nucleic Acids Res (1997) 4.89
Bovine papilloma virus deoxyribonucleic acid: a novel eucaryotic cloning vector. Mol Cell Biol (1981) 4.75
The Pax4 gene is essential for differentiation of insulin-producing beta cells in the mammalian pancreas. Nature (1997) 4.69
Pax6 is required for the multipotent state of retinal progenitor cells. Cell (2001) 4.65
Pax6 is required for differentiation of glucagon-producing alpha-cells in mouse pancreas. Nature (1997) 4.58
Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development. Cell (1998) 4.53
A family of octamer-specific proteins present during mouse embryogenesis: evidence for germline-specific expression of an Oct factor. EMBO J (1989) 4.47
Oct-4: a germline-specific transcription factor mapping to the mouse t-complex. EMBO J (1990) 4.42
Six3, a murine homologue of the sine oculis gene, demarcates the most anterior border of the developing neural plate and is expressed during eye development. Development (1995) 3.90
Splicing as a requirement for biogenesis of functional 16S mRNA of simian virus 40. Proc Natl Acad Sci U S A (1979) 3.89
Pax6 activity in the lens primordium is required for lens formation and for correct placement of a single retina in the eye. Genes Dev (2000) 3.85
Pax-3, a novel murine DNA binding protein expressed during early neurogenesis. EMBO J (1991) 3.85
Homeotic transformations of murine vertebrae and concomitant alteration of Hox codes induced by retinoic acid. Cell (1991) 3.71
Waardenburg's syndrome patients have mutations in the human homologue of the Pax-3 paired box gene. Nature (1992) 3.63
Pax-2 controls multiple steps of urogenital development. Development (1995) 3.42
BK viral enhancer element and a human cellular homolog. Science (1983) 3.36
A multigene family encoding several "finger" structures is present and differentially active in mammalian genomes. Cell (1987) 3.09
Prox1 function is crucial for mouse lens-fibre elongation. Nat Genet (1999) 3.01
Production of chimaeric mice containing embryonic stem (ES) cells carrying a homoeobox Hox 1.1 allele mutated by homologous recombination. Nature (1989) 2.94
Identification of a precursor in the biosynthesis of the p21 transforming protein of harvey murine sarcoma virus. J Virol (1982) 2.89
Activation of NF-kappaB by Akt upregulates Snail expression and induces epithelium mesenchyme transition. Oncogene (2007) 2.87
Processing and expression of early SV40 mRNA: a role for RNA conformation in splicing. Cell (1979) 2.80
Pax6 controls radial glia differentiation in the cerebral cortex. Neuron (1998) 2.78
Expression of simian virus 40-rat preproinsulin recombinants in monkey kidney cells: use of preproinsulin RNA processing signals. Proc Natl Acad Sci U S A (1981) 2.76
Follicular cells of the thyroid gland require Pax8 gene function. Nat Genet (1998) 2.75
Post-transcriptional control of myc and p53 expression during differentiation of the embryonal carcinoma cell line F9. Nature (1985) 2.75
Pax2, a new murine paired-box-containing gene and its expression in the developing excretory system. Development (1990) 2.72
Murine developmental control genes. Science (1990) 2.71
Cell type-specific transcriptional enhancement in vitro requires the presence of trans-acting factors. EMBO J (1985) 2.70
Distinct cis-essential modules direct the time-space pattern of the Pax6 gene activity. Dev Biol (1999) 2.70
Octamer binding proteins confer transcriptional activity in early mouse embryogenesis. EMBO J (1989) 2.70
Pax: a murine multigene family of paired box-containing genes. Genomics (1991) 2.60
Pax-3 is required for the development of limb muscles: a possible role for the migration of dermomyotomal muscle progenitor cells. Development (1994) 2.45
Homeobox genes and connective tissue patterning. Development (1995) 2.43
Pax8, a murine paired box gene expressed in the developing excretory system and thyroid gland. Development (1990) 2.42
Cortical upper layer neurons derive from the subventricular zone as indicated by Svet1 gene expression. Development (2001) 2.37
Pax2 contributes to inner ear patterning and optic nerve trajectory. Development (1996) 2.33
Dysgenesis of cephalic neural crest derivatives in Pax7-/- mutant mice. Development (1996) 2.31
Origin of DNA replication in papovavirus chromatin is recognized by endogenous endonuclease. Proc Natl Acad Sci U S A (1978) 2.24
Prox 1, a prospero-related homeobox gene expressed during mouse development. Mech Dev (1993) 2.21
Oct-6: a POU transcription factor expressed in embryonal stem cells and in the developing brain. EMBO J (1990) 2.19
Roles of Pax-genes in developing and adult brain as suggested by expression patterns. J Neurosci (1994) 2.19
A nexus between Oct-4 and E1A: implications for gene regulation in embryonic stem cells. Cell (1991) 2.18
Disruption of the murine homeobox gene Cdx1 affects axial skeletal identities by altering the mesodermal expression domains of Hox genes. Cell (1995) 2.15
The molecular basis of the undulated/Pax-1 mutation. Cell (1991) 2.14
The murine paired box gene, Pax7, is expressed specifically during the development of the nervous and muscular system. Mech Dev (1990) 2.12
Interdigital cell death can occur through a necrotic and caspase-independent pathway. Curr Biol (1999) 2.11
Pax 1, a member of a paired box homologous murine gene family, is expressed in segmented structures during development. Cell (1988) 2.05
An alpha-E-catenin gene trap mutation defines its function in preimplantation development. Proc Natl Acad Sci U S A (1997) 2.05
[Are French results in assisted reproductive techniques so bad?]. Gynecol Obstet Fertil (2007) 2.03
IGF-II induces rapid beta-catenin relocation to the nucleus during epithelium to mesenchyme transition. Oncogene (2001) 2.03
Structural analysis of murine genes containing homoeo box sequences and their expression in embryonal carcinoma cells. Nature (1985) 2.01
Spatially and temporally restricted expression of Pax2 during murine neurogenesis. Development (1990) 2.01
undulated, a mutation affecting the development of the mouse skeleton, has a point mutation in the paired box of Pax 1. Cell (1988) 2.01
Forebrain patterning defects in Small eye mutant mice. Development (1996) 1.95
A viral enhancer element specifically active in human haematopoietic cells. Nature (1985) 1.95
Magic enhancers? DNA (1984) 1.95
Efficient FLP recombination in mouse ES cells and oocytes. Genesis (2001) 1.94
The oncogenic potential of Pax genes. EMBO J (1993) 1.88
Mice lacking HSP90beta fail to develop a placental labyrinth. Development (2000) 1.83
Clustered homeo boxes are differentially expressed during murine development. Cell (1985) 1.80
Variations of cervical vertebrae after expression of a Hox-1.1 transgene in mice. Cell (1990) 1.79
Spatial specification of mammalian eye territories by reciprocal transcriptional repression of Pax2 and Pax6. Development (2000) 1.77
PAX8, a human paired box gene: isolation and expression in developing thyroid, kidney and Wilms' tumors. Development (1992) 1.77
Pax6 modulates the dorsoventral patterning of the mammalian telencephalon. J Neurosci (2000) 1.74
Pax6 lights-up the way for eye development. Curr Opin Cell Biol (2001) 1.74
Rescue of a splicing defective mutant by insertion of an heterologous intron. Nature (1980) 1.74
Pax genes and their roles in cell differentiation and development. Curr Opin Cell Biol (1996) 1.72
Interaction of distinct nuclear proteins with sequences controlling the expression of polyomavirus early genes. Mol Cell Biol (1986) 1.69
A mouse gene homologous to the Drosophila gene caudal is expressed in epithelial cells from the embryonic intestine. Genes Dev (1988) 1.68
Mutations in the PAX3 gene causing Waardenburg syndrome type 1 and type 2. Nat Genet (1993) 1.67
Netrin 1 is required for semicircular canal formation in the mouse inner ear. Development (2000) 1.65
Primary structure and nuclear localization of a murine homeodomain protein. Proc Natl Acad Sci U S A (1987) 1.63
Querkopf, a MYST family histone acetyltransferase, is required for normal cerebral cortex development. Development (2000) 1.63
Vax1, a novel homeobox-containing gene, directs development of the basal forebrain and visual system. Genes Dev (1999) 1.61
Targeted mutation of the murine goosecoid gene results in craniofacial defects and neonatal death. Development (1995) 1.55
New chimeric splice junction in adenovirus type 2-simian virus 40 hybrid viral mRNA. J Virol (1980) 1.53
Control of retinal ganglion cell axon growth: a new role for Sonic hedgehog. Development (2001) 1.47
The oncogenic potential of deregulated homeobox genes. Cell Growth Differ (1993) 1.47
Primary structure and developmental expression pattern of Hox 3.1, a member of the murine Hox 3 homeobox gene cluster. EMBO J (1988) 1.46
Efficiency assessment of the gene trap approach. Dev Dyn (1998) 1.45
Nuclear factors binding specific sequences within the immunoglobulin enhancer interact differentially with other enhancer elements. EMBO J (1986) 1.45
The metallochaperone Atox1 plays a critical role in perinatal copper homeostasis. Proc Natl Acad Sci U S A (2001) 1.45
Mouse Cdx-1 expression during gastrulation. Development (1993) 1.45
Six6 (Optx2) is a novel murine Six3-related homeobox gene that demarcates the presumptive pituitary/hypothalamic axis and the ventral optic stalk. Mech Dev (1999) 1.44