Published in J Virol on April 01, 1982
Purification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition method. Mol Cell Biol (1988) 13.78
Ras oncogenes: split personalities. Nat Rev Mol Cell Biol (2008) 7.91
Inhibition of NIH 3T3 cell proliferation by a mutant ras protein with preferential affinity for GDP. Mol Cell Biol (1988) 7.06
Harvey murine sarcoma virus p21 ras protein: biological and biochemical significance of the cysteine nearest the carboxy terminus. EMBO J (1984) 4.28
Post-translational processing of p21ras is two-step and involves carboxyl-methylation and carboxy-terminal proteolysis. EMBO J (1989) 3.51
Functional modification of a 21-kilodalton G protein when ADP-ribosylated by exoenzyme C3 of Clostridium botulinum. Mol Cell Biol (1988) 3.11
Dynamic fatty acylation of p21N-ras. EMBO J (1987) 2.99
Comparative biochemical properties of p21 ras molecules coded for by viral and cellular ras genes. J Virol (1982) 2.91
Mutational analysis of a ras catalytic domain. Mol Cell Biol (1986) 2.76
Guanine nucleotide activation of, and competition between, RAS proteins from Saccharomyces cerevisiae. Mol Cell Biol (1987) 2.45
A carboxyl-terminal cysteine residue is required for palmitic acid binding and biological activity of the ras-related yeast YPT1 protein. EMBO J (1988) 2.21
Fatty acylation is important but not essential for Saccharomyces cerevisiae RAS function. Mol Cell Biol (1987) 2.19
Processing and fatty acid acylation of RAS1 and RAS2 proteins in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1986) 2.16
Nucleotide sequence of two rasH related-genes isolated from the yeast Saccharomyces cerevisiae. Nucleic Acids Res (1984) 2.10
Posttranslational processing of p21 ras proteins involves palmitylation of the C-terminal tetrapeptide containing cysteine-186. J Virol (1985) 2.03
Direct identification of palmitic acid as the lipid attached to p21ras. Mol Cell Biol (1986) 2.02
Modification of nuclear lamin proteins by a mevalonic acid derivative occurs in reticulocyte lysates and requires the cysteine residue of the C-terminal CXXM motif. EMBO J (1989) 1.96
Expression of normal and transforming H-ras genes in Escherichia coli and purification of their encoded p21 proteins. Proc Natl Acad Sci U S A (1984) 1.94
The ras oncogene--an important regulatory element in lower eucaryotic organisms. Microbiol Rev (1989) 1.79
Purification and characterization of human H-ras proteins expressed in Escherichia coli. Mol Cell Biol (1985) 1.77
The int-1 proto-oncogene products are glycoproteins that appear to enter the secretory pathway. Mol Cell Biol (1987) 1.60
Mechanism of activation of an N-ras gene in the human fibrosarcoma cell line HT1080. EMBO J (1984) 1.56
Guanosine nucleotide binding by highly purified Ha-ras-encoded p21 protein produced in Escherichia coli. Proc Natl Acad Sci U S A (1984) 1.55
Photoaffinity labeling with GTP of viral p21 ras protein expressed in Escherichia coli. J Virol (1984) 1.54
Metabolic turnover of human c-rasH p21 protein of EJ bladder carcinoma and its normal cellular and viral homologs. Mol Cell Biol (1984) 1.45
The v-mos and H-ras oncogene expression represses glucocorticoid hormone-dependent transcription from the mouse mammary tumor virus LTR. EMBO J (1986) 1.41
Mouse cells contain two distinct ras gene mRNA species that can be translated into a p21 onc protein. Mol Cell Biol (1982) 1.34
A novel yeast mutant defective in the processing of ras proteins: assessment of the effect of the mutation on processing steps. EMBO J (1987) 1.33
Monoclonal antibodies of predefined specificity detect activated ras gene expression in human mammary and colon carcinomas. Proc Natl Acad Sci U S A (1984) 1.32
Heterologous expression and characterization of the human R-ras gene product. Mol Cell Biol (1987) 1.27
Regulation of a ras-related protein during development of Dictyostelium discoideum. Mol Cell Biol (1985) 1.19
Effects of two major activating lesions on the structure and conformation of human ras oncogene products. Proc Natl Acad Sci U S A (1985) 1.17
Transforming p21 ras protein: flexibility in the major variable region linking the catalytic and membrane-anchoring domains. EMBO J (1985) 1.16
Ras activity regulates cyclin E degradation by the Fbw7 pathway. Proc Natl Acad Sci U S A (2005) 1.15
Biosynthesis and interconversion of Drosophila nuclear lamin isoforms during normal growth and in response to heat shock. J Cell Biol (1987) 1.09
Diacylglycerol production in Xenopus laevis oocytes after microinjection of p21ras proteins is a consequence of activation of phosphatidylcholine metabolism. Mol Cell Biol (1990) 0.96
Acylation of the 176R (19-kilodalton) early region 1B protein of human adenovirus type 5. J Virol (1987) 0.96
Antibodies to the ras gene product inhibit adenylate cyclase and accelerate progesterone-induced cell division in Xenopus laevis oocytes. Mol Cell Biol (1986) 0.94
Development and analysis of a transformation-defective mutant of Harvey murine sarcoma tk virus and its gene product. J Virol (1985) 0.90
Antibody of predetermined specificity to a carboxy-terminal region of H-ras gene products inhibits their guanine nucleotide-binding function. Mol Cell Biol (1985) 0.82
Genetic factors and suppression of metastatic ability of v-Ha-ras-transfected rat mammary cancer cells. Proc Natl Acad Sci U S A (1992) 0.76
Expression of viral p21ras during acquisition of a transformed phenotype by rat adrenal cortex cells infected with Kirsten murine sarcoma virus. Mol Cell Biol (1986) 0.76
The p21 src genes of Harvey and Kirsten sarcoma viruses originate from divergent members of a family of normal vertebrate genes. Nature (1981) 8.44
Transfer of proteins across membranes. Annu Rev Biochem (1981) 5.55
The protein encoded by the transforming gene of avian sarcoma virus (pp60src) and a homologous protein in normal cells (pp60proto-src) are associated with the plasma membrane. Proc Natl Acad Sci U S A (1980) 4.99
Guanine nucleotide-binding and autophosphorylating activities associated with the p21src protein of Harvey murine sarcoma virus. Nature (1980) 4.43
Localization of the src gene product of the Harvey strain of MSV to plasma membrane of transformed cells by electron microscopic immunocytochemistry. Cell (1980) 4.35
Guanine nucleotide-binding activity as an assay for src protein of rat-derived murine sarcoma viruses. Proc Natl Acad Sci U S A (1979) 4.34
Identification of a sarcoma virus-coded phosphoprotein in nonproducer cells transformed by Kirsten or Harvey murine sarcoma virus. Virology (1979) 4.08
The assembly of proteins into biological membranes: The membrane trigger hypothesis. Annu Rev Biochem (1979) 4.05
p21 of Kirsten murine sarcoma virus is thermolabile in a viral mutant temperature sensitive for the maintenance of transformation. J Virol (1979) 2.94
In vivo chemical modification of proteins (post-translational modification). Annu Rev Biochem (1981) 2.91
Functional organization of the Harvey murine sarcoma virus genome. J Virol (1980) 2.46
Identification of a normal vertebrate cell protein related to the p21 src of Harvey murine sarcoma virus. Virology (1980) 2.15
Cleavage at aspartyl-prolyl bonds. Methods Enzymol (1977) 2.10
Markedly elevated levels of an endogenous sarc protein in a hemopoietic precursor cell line. Mol Cell Biol (1981) 1.83
Mapping of transforming region of the Harvey murine sarcoma virus genome by using insertion-deletion mutants constructed in vitro. Proc Natl Acad Sci U S A (1980) 1.56
SV40 recombinant molecules express the gene encoding p21 transforming protein of Harvey murine sarcoma virus. Nature (1981) 1.39
Isolation of adenylate cyclase-enriched membranes from mammalian cells using concanavalin A. J Biol Chem (1979) 1.22
Biosynthesis and processing of cellular and viral polyproteins. Nature (1980) 0.89
The genome of simian virus 40. Science (1978) 24.46
Multiple point mutations affecting the simian virus 40 enhancer. Science (1983) 13.69
Simian virus 40 tandem repeated sequences as an element of the early promoter. Proc Natl Acad Sci U S A (1981) 13.67
Host-specific activation of transcription by tandem repeats from simian virus 40 and Moloney murine sarcoma virus. Proc Natl Acad Sci U S A (1982) 12.30
Mechanism of activation of a human oncogene. Nature (1982) 12.09
Active human immunodeficiency virus protease is required for viral infectivity. Proc Natl Acad Sci U S A (1988) 10.77
Enhancer elements. Cell (1983) 10.41
Pax7 is required for the specification of myogenic satellite cells. Cell (2000) 9.88
Monoclonal antibodies to the p21 products of the transforming gene of Harvey murine sarcoma virus and of the cellular ras gene family. J Virol (1982) 8.88
The p21 src genes of Harvey and Kirsten sarcoma viruses originate from divergent members of a family of normal vertebrate genes. Nature (1981) 8.44
Characterization of enhancer elements in the long terminal repeat of Moloney murine sarcoma virus. J Virol (1984) 7.80
Nucleotide sequences of integrated Moloney sarcoma provirus long terminal repeats and their host and viral junctions. Proc Natl Acad Sci U S A (1980) 7.77
Helper-independent transformation by unintegrated Harvey sarcoma virus DNA. J Virol (1978) 7.75
Specific interaction between enhancer-containing molecules and cellular components. Cell (1984) 6.96
Participation of p53 cellular tumour antigen in transformation of normal embryonic cells. Nature (1985) 6.86
Whole-genome association study of bipolar disorder. Mol Psychiatry (2008) 6.80
Induction of murine C-type viruses from clonal lines of virus-free BALB-3T3 cells. Science (1971) 6.71
Characterization of highly immunogenic p66/p51 as the reverse transcriptase of HTLV-III/LAV. Science (1986) 6.53
Characterization of gp41 as the transmembrane protein coded by the HTLV-III/LAV envelope gene. Science (1985) 6.48
Intrinsic GTPase activity distinguishes normal and oncogenic ras p21 molecules. Proc Natl Acad Sci U S A (1984) 6.45
The genome of human papovavirus BKV. Cell (1979) 6.36
Standardized and simplified nomenclature for proteins common to all retroviruses. J Virol (1988) 6.31
Development of peripheral lymphoid organs and natural killer cells depends on the helix-loop-helix inhibitor Id2. Nature (1999) 6.23
Activation of SV40 genome by 72-base pair tandem repeats of Moloney sarcoma virus. Nature (1982) 6.02
Temporal control of gene expression in transgenic mice by a tetracycline-responsive promoter. Proc Natl Acad Sci U S A (1994) 5.71
New type of POU domain in germ line-specific protein Oct-4. Nature (1990) 5.65
Cloning of bovine GAP and its interaction with oncogenic ras p21. Nature (1988) 5.56
Prospect for prevention of human immunodeficiency virus infection: purified 120-kDa envelope glycoprotein induces neutralizing antibody. Proc Natl Acad Sci U S A (1986) 5.55
Analysis of two divergent rat genomic clones homologous to the transforming gene of Harvey murine sarcoma virus. Proc Natl Acad Sci U S A (1981) 5.51
Pax-6, a murine paired box gene, is expressed in the developing CNS. Development (1991) 5.49
Characterization of envelope and core structural gene products of HTLV-III with sera from AIDS patients. Science (1985) 5.42
Murine leukemia virus protease is encoded by the gag-pol gene and is synthesized through suppression of an amber termination codon. Proc Natl Acad Sci U S A (1985) 5.36
ras-Related gene sequences identified and isolated from Saccharomyces cerevisiae. Nature (1984) 5.32
Studies on the nucleic acid sequences of Kirsten sarcoma virus: a model for formation of a mammalian RNA-containing sarcoma virus. J Virol (1973) 5.28
Increasing mortality due to end-stage liver disease in patients with human immunodeficiency virus infection. Clin Infect Dis (2001) 5.27
Myristyl amino-terminal acylation of murine retrovirus proteins: an unusual post-translational proteins modification. Proc Natl Acad Sci U S A (1983) 5.12
Tumorigenic transformation of mammalian cells induced by a normal human gene homologous to the oncogene of Harvey murine sarcoma virus. Nature (1982) 5.08
RNA in mammalian sarcoma virus transformed nonproducer cells homologous to murine leukemia virus RNA. Virology (1973) 5.04
Transfection of molecularly cloned Friend murine leukemia virus DNA yields a highly leukemogenic helper-independent type C virus. J Virol (1980) 4.91
Cre-mediated gene deletion in the mammary gland. Nucleic Acids Res (1997) 4.89
BKV splice sequences based on analysis of preferred donor and acceptor sites. Nucleic Acids Res (1979) 4.86
Bovine papilloma virus deoxyribonucleic acid: a novel eucaryotic cloning vector. Mol Cell Biol (1981) 4.75
The Pax4 gene is essential for differentiation of insulin-producing beta cells in the mammalian pancreas. Nature (1997) 4.69
The transforming proteins of Rous sarcoma virus, Harvey sarcoma virus and Abelson virus contain tightly bound lipid. Cell (1982) 4.66
Murine leukemia virus maturation: protease region required for conversion from "immature" to "mature" core form and for virus infectivity. Virology (1985) 4.65
Pax6 is required for the multipotent state of retinal progenitor cells. Cell (2001) 4.65
Novel mechanism for RNA maturation: the leader sequences of simian virus 40 mRNA are not transcribed adjacent to the coding sequences. Proc Natl Acad Sci U S A (1977) 4.64
Dual evolutionary origin for the rat genetic sequences of Harvey murine sarcoma virus. J Virol (1980) 4.63
Pax6 is required for differentiation of glucagon-producing alpha-cells in mouse pancreas. Nature (1997) 4.58
Construction and isolation of a transmissible retrovirus containing the src gene of Harvey murine sarcoma virus and the thymidine kinase gene of herpes simplex virus type 1. J Virol (1981) 4.54
Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development. Cell (1998) 4.53
A family of octamer-specific proteins present during mouse embryogenesis: evidence for germline-specific expression of an Oct factor. EMBO J (1989) 4.47
Guanine nucleotide-binding and autophosphorylating activities associated with the p21src protein of Harvey murine sarcoma virus. Nature (1980) 4.43
Oct-4: a germline-specific transcription factor mapping to the mouse t-complex. EMBO J (1990) 4.42
Localization of the src gene product of the Harvey strain of MSV to plasma membrane of transformed cells by electron microscopic immunocytochemistry. Cell (1980) 4.35
Human immunodeficiency viruses. Science (1986) 4.34
Guanine nucleotide-binding activity as an assay for src protein of rat-derived murine sarcoma viruses. Proc Natl Acad Sci U S A (1979) 4.34
Mapping the spliced and unspliced late lytic SV40 RNAs. Cell (1978) 4.25
Requirement of either of a pair of ras-related genes of Saccharomyces cerevisiae for spore viability. Nature (1984) 4.23
In vivo modification of retroviral gag gene-encoded polyproteins by myristic acid. J Virol (1983) 4.09
Identification of a sarcoma virus-coded phosphoprotein in nonproducer cells transformed by Kirsten or Harvey murine sarcoma virus. Virology (1979) 4.08
Biochemical and immunological analysis of human immunodeficiency virus gag gene products p17 and p24. J Virol (1988) 4.06
Amino terminal myristylation of the protein kinase p60src, a retroviral transforming protein. Science (1985) 3.97
Harvey sarcoma virus: a second murine type C sarcoma virus with rat genetic information. J Virol (1974) 3.92
Molecular cloning of the Harvey sarcoma virus closed circular DNA intermediates: initial structural and biological characterization. J Virol (1979) 3.90
Six3, a murine homologue of the sine oculis gene, demarcates the most anterior border of the developing neural plate and is expressed during eye development. Development (1995) 3.90
Splicing as a requirement for biogenesis of functional 16S mRNA of simian virus 40. Proc Natl Acad Sci U S A (1979) 3.89
Pax6 activity in the lens primordium is required for lens formation and for correct placement of a single retina in the eye. Genes Dev (2000) 3.85
Pax-3, a novel murine DNA binding protein expressed during early neurogenesis. EMBO J (1991) 3.85
Homeotic transformations of murine vertebrae and concomitant alteration of Hox codes induced by retinoic acid. Cell (1991) 3.71
Separation of murine cellular and murine leukaemia virus DNA polymerases. Nat New Biol (1971) 3.71
Group-specific antigen expression during embryogenesis of the genome of the C-type RNA tumor virus: implications for ontogenesis and oncogenesis. Proc Natl Acad Sci U S A (1970) 3.71
Friend strain of spleen focus-forming virus: a recombinant between mouse type C ecotropic viral sequences and sequences related to xenotropic virus. J Virol (1977) 3.70
Thin-layer chromatography of sub-nanomole amounts of phenylthiohydantoin (PTH) amino acids on polyamide sheets. Anal Biochem (1973) 3.66
Waardenburg's syndrome patients have mutations in the human homologue of the Pax-3 paired box gene. Nature (1992) 3.63
Interactions of retroviral structural proteins with single-stranded nucleic acids. J Biol Chem (1987) 3.62
Friend strain of spleen focus-forming virus is a recombinant between ecotropic murine type C virus and the env gene region of xenotropic type C virus. Proc Natl Acad Sci U S A (1977) 3.62
Mutant ras-encoded proteins with altered nucleotide binding exert dominant biological effects. Proc Natl Acad Sci U S A (1986) 3.59
Nucleotide sequence of the p21 transforming protein of Harvey murine sarcoma virus. Science (1982) 3.55
Human genome contains four genes homologous to transforming genes of Harvey and Kirsten murine sarcoma viruses. Proc Natl Acad Sci U S A (1982) 3.48
Pax-2 controls multiple steps of urogenital development. Development (1995) 3.42
BK viral enhancer element and a human cellular homolog. Science (1983) 3.36
Separation of sarcoma virus-specific and leukemia virus-specific genetic sequences of Moloney sarcoma virus. Proc Natl Acad Sci U S A (1975) 3.28
Inhibition of lymphocyte proliferation by a synthetic peptide homologous to retroviral envelope proteins. Science (1985) 3.27
Radioimmunoassay of mammalian type C viral proteins. I. Species specific reactions of murine and feline viruses. J Immunol (1972) 3.23
Primary structure of the low molecular weight nucleic acid-binding proteins of murine leukemia viruses. J Biol Chem (1981) 3.21
Proposal for naming host cell-derived inserts in retrovirus genomes. J Virol (1981) 3.18