Bennett Van Houten

Author PubWeight™ 129.43‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Standardizing global gene expression analysis between laboratories and across platforms. Nat Methods 2005 6.23
2 Quantitative PCR-based measurement of nuclear and mitochondrial DNA damage and repair in mammalian cells. Methods Mol Biol 2006 2.87
3 Mutant huntingtin impairs axonal trafficking in mammalian neurons in vivo and in vitro. Mol Cell Biol 2004 2.65
4 Energy metabolism in human pluripotent stem cells and their differentiated counterparts. PLoS One 2011 2.64
5 Prokaryotic nucleotide excision repair: the UvrABC system. Chem Rev 2006 2.37
6 Basal transcription defect discriminates between xeroderma pigmentosum and trichothiodystrophy in XPD patients. Mol Cell 2003 2.12
7 Integrating phenotypic and expression profiles to map arsenic-response networks. Genome Biol 2004 1.90
8 High-mobility group box 1 is essential for mitochondrial quality control. Cell Metab 2011 1.89
9 Adipose tissue and adipocytes support tumorigenesis and metastasis. Biochim Biophys Acta 2013 1.85
10 Crystal structure of the FeS cluster-containing nucleotide excision repair helicase XPD. PLoS Biol 2008 1.81
11 Crucial role for DNA ligase III in mitochondria but not in Xrcc1-dependent repair. Nature 2011 1.80
12 Role of mitochondria in toxic oxidative stress. Mol Interv 2005 1.76
13 Alterations in bioenergetics due to changes in mitochondrial DNA copy number. Methods 2010 1.62
14 NIEHS extramural global environmental health portfolio: opportunities for collaboration. Environ Health Perspect 2008 1.61
15 Mitochondrial dysfunction in neurodegenerative diseases and cancer. Environ Mol Mutagen 2010 1.60
16 Mitochondrial DNA repair and aging. Mutat Res 2002 1.60
17 Structural basis for DNA recognition and processing by UvrB. Nat Struct Mol Biol 2006 1.51
18 Cell sorting experiments link persistent mitochondrial DNA damage with loss of mitochondrial membrane potential and apoptotic cell death. J Biol Chem 2002 1.49
19 Withaferin A-induced apoptosis in human breast cancer cells is mediated by reactive oxygen species. PLoS One 2011 1.48
20 Phenethyl isothiocyanate inhibits oxidative phosphorylation to trigger reactive oxygen species-mediated death of human prostate cancer cells. J Biol Chem 2010 1.46
21 The beta -hairpin motif of UvrB is essential for DNA binding, damage processing, and UvrC-mediated incisions. J Biol Chem 2001 1.46
22 Decline of nucleotide excision repair capacity in aging Caenorhabditis elegans. Genome Biol 2007 1.41
23 Collaborative dynamic DNA scanning by nucleotide excision repair proteins investigated by single- molecule imaging of quantum-dot-labeled proteins. Mol Cell 2010 1.40
24 Metabolic symbiosis in cancer: refocusing the Warburg lens. Mol Carcinog 2012 1.40
25 Measuring oxidative mtDNA damage and repair using quantitative PCR. Methods Mol Biol 2002 1.40
26 Mitochondrial hTERT exacerbates free-radical-mediated mtDNA damage. Aging Cell 2004 1.37
27 Mitochondrial localization of telomerase as a determinant for hydrogen peroxide-induced mitochondrial DNA damage and apoptosis. Hum Mol Genet 2006 1.32
28 Altered gene expression and DNA damage in peripheral blood cells from Friedreich's ataxia patients: cellular model of pathology. PLoS Genet 2010 1.32
29 Structural insights into the first incision reaction during nucleotide excision repair. EMBO J 2005 1.30
30 Mitochondrial hyperfusion induced by loss of the fission protein Drp1 causes ATM-dependent G2/M arrest and aneuploidy through DNA replication stress. J Cell Sci 2012 1.30
31 Homologous recombination but not nucleotide excision repair plays a pivotal role in tolerance of DNA-protein cross-links in mammalian cells. J Biol Chem 2009 1.29
32 Conceptual model of comprehensive research metrics for improved human health and environment. Environ Health Perspect 2008 1.29
33 Reduction in frataxin causes progressive accumulation of mitochondrial damage. Hum Mol Genet 2003 1.24
34 Double-strand break formation during nucleotide excision repair of a DNA interstrand cross-link. Biochemistry 2009 1.23
35 Mutations associated with base excision repair deficiency and methylation-induced genotoxic stress. Proc Natl Acad Sci U S A 2002 1.20
36 UvrB domain 4, an autoinhibitory gate for regulation of DNA binding and ATPase activity. J Biol Chem 2006 1.20
37 Initiation of repair of DNA-polypeptide cross-links by the UvrABC nuclease. Biochemistry 2005 1.19
38 Asbestos induces mitochondrial DNA damage and dysfunction linked to the development of apoptosis. Am J Physiol Lung Cell Mol Physiol 2003 1.18
39 Apoptosis induced by persistent single-strand breaks in mitochondrial genome: critical role of EXOG (5'-EXO/endonuclease) in their repair. J Biol Chem 2011 1.18
40 Inhibiting systemic autophagy during interleukin 2 immunotherapy promotes long-term tumor regression. Cancer Res 2012 1.17
41 Mitochondrial and nuclear DNA defects in Saccharomyces cerevisiae with mutations in DNA polymerase gamma associated with progressive external ophthalmoplegia. Hum Mol Genet 2005 1.16
42 Prokaryotic nucleotide excision repair. Cold Spring Harb Perspect Biol 2013 1.16
43 Probing for DNA damage with β-hairpins: similarities in incision efficiencies of bulky DNA adducts by prokaryotic and human nucleotide excision repair systems in vitro. DNA Repair (Amst) 2011 1.15
44 Interactions between UvrA and UvrB: the role of UvrB's domain 2 in nucleotide excision repair. EMBO J 2004 1.15
45 Analysis of DNA damage and repair in nuclear and mitochondrial DNA of animal cells using quantitative PCR. Methods Mol Biol 2012 1.13
46 Oxidants and not alkylating agents induce rapid mtDNA loss and mitochondrial dysfunction. DNA Repair (Amst) 2012 1.12
47 The C-terminal zinc finger of UvrA does not bind DNA directly but regulates damage-specific DNA binding. J Biol Chem 2006 1.10
48 Importance of glycolysis and oxidative phosphorylation in advanced melanoma. Mol Cancer 2012 1.10
49 Mitochondrial structure, function and dynamics are temporally controlled by c-Myc. PLoS One 2012 1.09
50 Structure of the C-terminal half of UvrC reveals an RNase H endonuclease domain with an Argonaute-like catalytic triad. EMBO J 2007 1.09
51 Functional characterization and atomic force microscopy of a DNA repair protein conjugated to a quantum dot. Nano Lett 2008 1.09
52 Toward the assessment of scientific and public health impacts of the National Institute of Environmental Health Sciences Extramural Asthma Research Program using available data. Environ Health Perspect 2009 1.08
53 Sequence context- and temperature-dependent nucleotide excision repair of a benzo[a]pyrene diol epoxide-guanine DNA adduct catalyzed by thermophilic UvrABC proteins. Biochemistry 2007 1.08
54 Analyzing the handoff of DNA from UvrA to UvrB utilizing DNA-protein photoaffinity labeling. J Biol Chem 2004 1.07
55 Repair activity of base and nucleotide excision repair enzymes for guanine lesions induced by nitrosative stress. Nucleic Acids Res 2005 1.06
56 ATP13A2 regulates mitochondrial bioenergetics through macroautophagy. Neurobiol Dis 2011 1.06
57 Mitochondria, energetics, epigenetics, and cellular responses to stress. Environ Health Perspect 2014 1.03
58 DNA tandem lesion repair by strand displacement synthesis and nucleotide excision repair. Biochemistry 2008 1.03
59 An altered redox balance mediates the hypersensitivity of Cockayne syndrome primary fibroblasts to oxidative stress. Aging Cell 2012 1.02
60 Novel method for site-specific induction of oxidative DNA damage reveals differences in recruitment of repair proteins to heterochromatin and euchromatin. Nucleic Acids Res 2013 1.02
61 Quantitative proteomics reveal ATM kinase-dependent exchange in DNA damage response complexes. J Proteome Res 2012 1.01
62 3-nitropropionic acid-induced hydrogen peroxide, mitochondrial DNA damage, and cell death are attenuated by Bcl-2 overexpression in PC12 cells. Brain Res Mol Brain Res 2005 1.01
63 Structural and functional characterization of the human DNA repair helicase XPD by comparative molecular modeling and site-directed mutagenesis of the bacterial repair protein UvrB. J Biol Chem 2002 0.99
64 Removal of misincorporated ribonucleotides from prokaryotic genomes: an unexpected role for nucleotide excision repair. PLoS Genet 2013 0.98
65 Nucleotide excision repair of a DNA interstrand cross-link produces single- and double-strand breaks. Biochemistry 2010 0.97
66 Mitochondrial and nuclear DNA damage induced by 5-aminolevulinic acid. Arch Biochem Biophys 2004 0.96
67 Mitochondrial respiration--an important therapeutic target in melanoma. PLoS One 2012 0.95
68 NMR analysis of [methyl-13C]methionine UvrB from Bacillus caldotenax reveals UvrB-domain 4 heterodimer formation in solution. J Mol Biol 2007 0.95
69 The transition of closely opposed lesions to double-strand breaks during long-patch base excision repair is prevented by the coordinated action of DNA polymerase delta and Rad27/Fen1. Mol Cell Biol 2008 0.95
70 Quantitative PCR-based measurement of nuclear and mitochondrial DNA damage and repair in mammalian cells. Methods Mol Biol 2014 0.95
71 Novel combination of mitochondrial division inhibitor 1 (mdivi-1) and platinum agents produces synergistic pro-apoptotic effect in drug resistant tumor cells. Oncotarget 2014 0.94
72 Vanadium-induced HB-EGF expression in human lung fibroblasts is oxidant dependent and requires MAP kinases. Am J Physiol Lung Cell Mol Physiol 2003 0.94
73 The Shu complex interacts with Rad51 through the Rad51 paralogues Rad55-Rad57 to mediate error-free recombination. Nucleic Acids Res 2013 0.94
74 Dynamics of lesion processing by bacterial nucleotide excision repair proteins. Prog Mol Biol Transl Sci 2012 0.93
75 Identification of residues within UvrB that are important for efficient DNA binding and damage processing. J Biol Chem 2004 0.92
76 Cooperative damage recognition by UvrA and UvrB: identification of UvrA residues that mediate DNA binding. DNA Repair (Amst) 2008 0.91
77 A general path for large-scale solubilization of cellular proteins: from membrane receptors to multiprotein complexes. Protein Expr Purif 2012 0.91
78 Single-nucleotide base excision repair DNA polymerase activity in C. elegans in the absence of DNA polymerase β. Nucleic Acids Res 2011 0.90
79 Point mutations in c-Myc uncouple neoplastic transformation from multiple other phenotypes in rat fibroblasts. PLoS One 2010 0.90
80 Damaged DNA induced UV-damaged DNA-binding protein (UV-DDB) dimerization and its roles in chromatinized DNA repair. Proc Natl Acad Sci U S A 2012 0.90
81 The role of dynamin-related protein 1 in cancer growth: a promising therapeutic target? Expert Opin Ther Targets 2013 0.90
82 DNA wrapping is required for DNA damage recognition in the Escherichia coli DNA nucleotide excision repair pathway. Proc Natl Acad Sci U S A 2009 0.89
83 Real-time single-molecule imaging reveals a direct interaction between UvrC and UvrB on DNA tightropes. Nucleic Acids Res 2013 0.88
84 Efficient processing of TFO-directed psoralen DNA interstrand crosslinks by the UvrABC nuclease. Nucleic Acids Res 2008 0.88
85 Exploring damage recognition models in prokaryotic nucleotide excision repair with a benzo[a]pyrene-derived lesion in UvrB. Biochemistry 2009 0.88
86 Repair of hydantoin lesions and their amine adducts in DNA by base and nucleotide excision repair. J Am Chem Soc 2013 0.87
87 Vanadium-induced STAT-1 activation in lung myofibroblasts requires H2O2 and P38 MAP kinase. Free Radic Biol Med 2003 0.86
88 Mitochondrial DNA-depleted A549 cells are resistant to bleomycin. Am J Physiol Lung Cell Mol Physiol 2012 0.86
89 Intrastrand DNA cross-links as tools for studying DNA replication and repair: two-, three-, and four-carbon tethers between the N(2) positions of adjacent guanines. Biochemistry 2002 0.86
90 SnapShot: Mitochondrial quality control. Cell 2011 0.86
91 Single-molecule analysis reveals human UV-damaged DNA-binding protein (UV-DDB) dimerizes on DNA via multiple kinetic intermediates. Proc Natl Acad Sci U S A 2014 0.85
92 DNA damage in normally and prematurely aged mice. Aging Cell 2013 0.85
93 Robust incision of Benoz[a]pyrene-7,8-dihyrodiol-9,10-epoxide-DNA adducts by a recombinant thermoresistant interspecies combination UvrABC endonuclease system. Biochemistry 2006 0.84
94 Supercoiled DNA promotes formation of intercalated cis-N2-deoxyguanine adducts and base-stacked trans-N2-deoxyguanine adducts by (+)-7R,8S-dihydrodiol-9S,10R-epoxy-7,8,9,10-tetra- hydrobenzo[a]pyrene. Chem Res Toxicol 2004 0.84
95 DNA repair gets physical: mapping an XPA-binding site on ERCC1. DNA Repair (Amst) 2008 0.83
96 Identification of a chemical that inhibits the mycobacterial UvrABC complex in nucleotide excision repair. Biochemistry 2011 0.83
97 XPB helicase regulates DNA incision by the Thermoplasma acidophilum endonuclease Bax1. DNA Repair (Amst) 2012 0.82
98 Bioenergetic analysis of intact mammalian cells using the Seahorse XF24 Extracellular Flux analyzer and a luciferase ATP assay. Methods Mol Biol 2014 0.82
99 Integrated proteomic and metabolic analysis of breast cancer progression. PLoS One 2013 0.81
100 Proceedings of a workshop on DNA adducts: biological significance and applications to risk assessment Washington, DC, April 13-14, 2004. Toxicol Appl Pharmacol 2005 0.81
101 Reduced sulfhydryls maintain specific incision of BPDE-DNA adducts by recombinant thermoresistant Bacillus caldotenax UvrABC endonuclease. Protein Expr Purif 2003 0.80
102 Bax1 is a novel endonuclease: implications for archaeal nucleotide excision repair. J Biol Chem 2009 0.79
103 Functional characterization of 8-oxoguanine DNA glycosylase of Trypanosoma cruzi. PLoS One 2012 0.79
104 Activity of nucleotide excision repair enzymes for oxanine cross-link lesions. Nucleic Acids Symp Ser (Oxf) 2005 0.79
105 The role of CSA and CSB protein in the oxidative stress response. Mech Ageing Dev 2013 0.78
106 Integrating multiple views of the cell: DNA repair jumps to higher level at Stowe workshop. DNA Repair (Amst) 2006 0.76
107 Survival choices. Nat Cell Biol 2006 0.76
108 Single molecule approaches: watching DNA repair one molecule at a time. Preface. DNA Repair (Amst) 2014 0.75
109 Meeting report: EU-US Workshop on Molecular Signatures of DNA Damage-Induced Stress Responses. Cortona, Italy, 26-30 September 2003. Mutat Res 2004 0.75
110 Fourth DNA repair workshop on DNA damage and repair: mechanisms and biological consequences Smolenice Castle, 2-5 May 2004. DNA Repair (Amst) 2004 0.75
111 Conceptual model of comprehensive research metrics for improved human health and environment. Cien Saude Colet 2009 0.75
112 Meeting report. Second EU-US workshop on systems level understanding of DNA damage responses. Mutat Res 2006 0.75