Published in J Virol on December 01, 2001
The diversity of retrotransposons and the properties of their reverse transcriptases. Virus Res (2008) 1.51
Transcription factor binding sites are genetic determinants of retroviral integration in the human genome. PLoS One (2009) 1.46
Histones Are Rapidly Loaded onto Unintegrated Retroviral DNAs Soon after Nuclear Entry. Cell Host Microbe (2016) 1.38
Protein inhibitor of activated STAT Y (PIASy) and a splice variant lacking exon 6 enhance sumoylation but are not essential for embryogenesis and adult life. Mol Cell Biol (2004) 1.24
Specificity of interaction of INI1/hSNF5 with retroviral integrases and its functional significance. J Virol (2004) 1.14
p12 tethers the murine leukemia virus pre-integration complex to mitotic chromosomes. PLoS Pathog (2012) 1.10
Identifying and characterizing a functional HIV-1 reverse transcriptase-binding site on integrase. J Biol Chem (2009) 1.03
Ty3 integrase is required for initiation of reverse transcription. J Virol (2002) 0.98
A novel function for spumaretrovirus integrase: an early requirement for integrase-mediated cleavage of 2 LTR circles. Retrovirology (2005) 0.92
Gammaretroviral vectors: biology, technology and application. Viruses (2011) 0.91
Subunit-specific analysis of the human immunodeficiency virus type 1 reverse transcriptase in vivo. J Virol (2004) 0.91
Role of integrase in reverse transcription of the Saccharomyces cerevisiae retrotransposon Ty1. Eukaryot Cell (2005) 0.91
Replication of chimeric human immunodeficiency virus type 1 (HIV-1) containing HIV-2 integrase (IN): naturally selected mutations in IN augment DNA synthesis. J Virol (2003) 0.88
Cooperation between reverse transcriptase and integrase during reverse transcription and formation of the preintegrative complex of Ty1. Eukaryot Cell (2006) 0.86
Structural and sequencing analysis of local target DNA recognition by MLV integrase. Nucleic Acids Res (2015) 0.82
Retroviral Integrase: Then and Now. Annu Rev Virol (2015) 0.77
Transcription factor YY1 interacts with retroviral integrases and facilitates integration of moloney murine leukemia virus cDNA into the host chromosomes. J Virol (2010) 0.77
Retroviral DNA Transposition: Themes and Variations. Microbiol Spectr (2014) 0.76
Construction and analysis of deletion mutations in the pol gene of Moloney murine leukemia virus: a new viral function required for productive infection. Cell (1984) 7.16
A mutant murine leukemia virus with a single missense codon in pol is defective in a function affecting integration. Proc Natl Acad Sci U S A (1984) 5.81
Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors. J Virol (1999) 5.35
HIV-1 infection of nondividing cells through the recognition of integrase by the importin/karyopherin pathway. Proc Natl Acad Sci U S A (1997) 4.59
HIV-1 Gag mutants can dominantly interfere with the replication of the wild-type virus. Cell (1989) 4.40
Multiple effects of mutations in human immunodeficiency virus type 1 integrase on viral replication. J Virol (1995) 4.27
kat: a high-efficiency retroviral transduction system for primary human T lymphocytes. Blood (1994) 2.94
Human immunodeficiency virus type 1 integrase mutants retain in vitro integrase activity yet fail to integrate viral DNA efficiently during infection. J Virol (1996) 2.82
Genetic analysis of the human immunodeficiency virus type 1 integrase protein. J Virol (1994) 2.26
Functional RT and IN incorporated into HIV-1 particles independently of the Gag/Pol precursor protein. EMBO J (1997) 2.23
Genetic analysis of human immunodeficiency virus type 1 integrase and the U3 att site: unusual phenotype of mutants in the zinc finger-like domain. J Virol (1995) 2.22
Human immunodeficiency virus type 1 integrase protein promotes reverse transcription through specific interactions with the nucleoprotein reverse transcription complex. J Virol (1999) 2.16
Transactivation of the minus-strand DNA transfer by nucleocapsid protein during reverse transcription of the retroviral genome. EMBO J (1994) 2.16
In vivo analysis of retroviral integrase structure and function. Adv Virus Res (1999) 1.82
Targeting foreign proteins to human immunodeficiency virus particles via fusion with Vpr and Vpx. J Virol (1995) 1.77
Analysis of mutations in the integration function of Moloney murine leukemia virus: effects on DNA binding and cutting. J Virol (1990) 1.75
Lack of integrase can markedly affect human immunodeficiency virus type 1 particle production in the presence of an active viral protease. J Virol (1996) 1.71
Analysis of mutant Moloney murine leukemia viruses containing linker insertion mutations in the 3' region of pol. J Virol (1988) 1.63
Analysis of human immunodeficiency virus type 1 integrase mutants. Virology (1995) 1.58
Conserved sequences in the carboxyl terminus of integrase that are essential for human immunodeficiency virus type 1 replication. J Virol (1996) 1.44
Extensive regions of pol are required for efficient human immunodeficiency virus polyprotein processing and particle maturation. Virology (1996) 1.26
Mutational analysis of the carboxyl terminus of the Moloney murine leukemia virus integration protein. J Virol (1991) 1.21
Lentiviral vector transduction of hematopoietic stem cells that mediate long-term reconstitution of lethally irradiated mice. Stem Cells (2000) 1.17
Expression of human immunodeficiency virus type 1 reverse transcriptase in trans during virion release and after infection. J Virol (1996) 1.10
Incorporation of functional human immunodeficiency virus type 1 integrase into virions independent of the Gag-Pol precursor protein. J Virol (1997) 1.01
Mutations in nonconserved domains of Ty3 integrase affect multiple stages of the Ty3 life cycle. J Virol (1999) 1.00
Targeting human immunodeficiency virus (HIV) type 2 integrase protein into HIV type 1. J Virol (1999) 0.84
The complete genome sequence of the gram-positive bacterium Bacillus subtilis. Nature (1997) 33.47
CHARMM: the biomolecular simulation program. J Comput Chem (2009) 27.71
Brain development during childhood and adolescence: a longitudinal MRI study. Nat Neurosci (1999) 18.57
An STS-based map of the human genome. Science (1995) 17.72
A gene map of the human genome. Science (1996) 14.32
A physical map of 30,000 human genes. Science (1998) 12.43
High levels of HIV-1 in plasma during all stages of infection determined by competitive PCR. Science (1993) 12.22
High titers of cytopathic virus in plasma of patients with symptomatic primary HIV-1 infection. N Engl J Med (1991) 7.01
Representing information in patient reports using natural language processing and the extensible markup language. J Am Med Inform Assoc (1999) 6.76
Sensitivity of human immunodeficiency virus type 1 to the fusion inhibitor T-20 is modulated by coreceptor specificity defined by the V3 loop of gp120. J Virol (2000) 6.71
Are Latinos less satisfied with communication by health care providers? J Gen Intern Med (1999) 5.26
Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells. Nature (1997) 5.08
The PX domains of p47phox and p40phox bind to lipid products of PI(3)K. Nat Cell Biol (2001) 4.64
Inactivation of the tumor suppressor PTEN/MMAC1 in advanced human prostate cancer through loss of expression. Proc Natl Acad Sci U S A (1998) 4.40
Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function. Genes Dev (1994) 4.30
Chalcones: an update on cytotoxic and chemoprotective properties. Curr Med Chem (2005) 3.97
Influenza neuraminidase inhibitors possessing a novel hydrophobic interaction in the enzyme active site: design, synthesis, and structural analysis of carbocyclic sialic acid analogues with potent anti-influenza activity. J Am Chem Soc (1997) 3.69
The induction of meningeal inflammation by components of the pneumococcal cell wall. J Infect Dis (1985) 3.66
Loss of function of a rice brassinosteroid insensitive1 homolog prevents internode elongation and bending of the lamina joint. Plant Cell (2000) 3.56
Human cytomegalovirus with IE-2 (UL122) deleted fails to express early lytic genes. J Virol (2001) 3.50
Solution structure of a 142-residue recombinant prion protein corresponding to the infectious fragment of the scrapie isoform. Proc Natl Acad Sci U S A (1997) 3.42
The highly reduced genome of an enslaved algal nucleus. Nature (2001) 3.31
The CXC chemokine receptor 2, CXCR2, is the putative receptor for ELR+ CXC chemokine-induced angiogenic activity. J Immunol (2000) 3.26
DNA structure-dependent requirements for yeast RAD genes in gene conversion. Nature (1995) 3.15
Chemical etiology of nucleic acid structure: the alpha-threofuranosyl-(3'-->2') oligonucleotide system. Science (2000) 3.11
Regulation of CSF1 promoter by the SWI/SNF-like BAF complex. Cell (2001) 3.10
Prevalence of diabetes and impaired fasting glucose in the Chinese adult population: International Collaborative Study of Cardiovascular Disease in Asia (InterASIA). Diabetologia (2003) 3.00
A short-term clinical evaluation of L-697,661, a non-nucleoside inhibitor of HIV-1 reverse transcriptase. L-697,661 Working Group. N Engl J Med (1993) 2.98
Virus-assisted mapping of neural inputs to a feeding center in the hypothalamus. Science (2001) 2.98
Longitudinal pattern of regional brain volume change differentiates normal aging from MCI. Neurology (2009) 2.84
mdm-2 inhibits the G1 arrest and apoptosis functions of the p53 tumor suppressor protein. Mol Cell Biol (1996) 2.78
The BCL11 gene family: involvement of BCL11A in lymphoid malignancies. Blood (2001) 2.77
Fluorescence resonance energy transfer from cyan to yellow fluorescent protein detected by acceptor photobleaching using confocal microscopy and a single laser. J Microsc (2003) 2.74
Processing of the notch ligand delta by the metalloprotease Kuzbanian. Science (1999) 2.71
Plasma levels of insulin-like growth factor-I and lung cancer risk: a case-control analysis. J Natl Cancer Inst (1999) 2.68
Direct binding of G-protein betagamma complex to voltage-dependent calcium channels. Nature (1997) 2.60
Sequestration and inhibition of Daxx-mediated transcriptional repression by PML. Mol Cell Biol (2000) 2.59
Different forms of TFIIH for transcription and DNA repair: holo-TFIIH and a nucleotide excision repairosome. Cell (1995) 2.58
p300 is a component of an estrogen receptor coactivator complex. Proc Natl Acad Sci U S A (1996) 2.58
Past adult lead exposure is linked to neurodegeneration measured by brain MRI. Neurology (2006) 2.52
CIDE, a novel family of cell death activators with homology to the 45 kDa subunit of the DNA fragmentation factor. EMBO J (1998) 2.44
Molecular subtyping of Treponema pallidum subspecies pallidum. Sex Transm Dis (1998) 2.44
Evaluating the UMLS as a source of lexical knowledge for medical language processing. Proc AMIA Symp (2001) 2.41
Modulation of nucleotide excision repair capacity by XPD polymorphisms in lung cancer patients. Cancer Res (2001) 2.37
Individual patient diagnosis of AD and FTD via high-dimensional pattern classification of MRI. Neuroimage (2008) 2.36
Apoptosis in a neonatal rat model of cerebral hypoxia-ischemia. Stroke (1998) 2.35
Evolution of an enzyme activity: crystallographic structure at 2-A resolution of cephalosporinase from the ampC gene of Enterobacter cloacae P99 and comparison with a class A penicillinase. Proc Natl Acad Sci U S A (1993) 2.34
Epidemiological link between exposure to poultry and all influenza A(H7N9) confirmed cases in Huzhou city, China, March to May 2013. Euro Surveill (2013) 2.34
Vesicular stomatitis virus matrix protein inhibits host cell gene expression by targeting the nucleoporin Nup98. Mol Cell (2000) 2.33
JNK targets p53 ubiquitination and degradation in nonstressed cells. Genes Dev (1998) 2.29
Bleomycin-induced pulmonary fibrosis in fibrinogen-null mice. J Clin Invest (2000) 2.26
A natural BH3 mimetic induces autophagy in apoptosis-resistant prostate cancer via modulating Bcl-2-Beclin1 interaction at endoplasmic reticulum. Cell Death Differ (2010) 2.25
Induction of Alzheimer-like beta-amyloid immunoreactivity in the brains of rabbits with dietary cholesterol. Exp Neurol (1994) 2.25
Error-free and error-prone lesion bypass by human DNA polymerase kappa in vitro. Nucleic Acids Res (2000) 2.25
The Vif protein of human and simian immunodeficiency viruses is packaged into virions and associates with viral core structures. J Virol (1995) 2.25
Pattern of mutation in the genome of influenza A virus on adaptation to increased virulence in the mouse lung: identification of functional themes. Proc Natl Acad Sci U S A (2001) 2.25
DNA repair synthesis during base excision repair in vitro is catalyzed by DNA polymerase epsilon and is influenced by DNA polymerases alpha and delta in Saccharomyces cerevisiae. Mol Cell Biol (1993) 2.23
Functional RT and IN incorporated into HIV-1 particles independently of the Gag/Pol precursor protein. EMBO J (1997) 2.23
Case-control study of the D2 dopamine receptor gene and smoking status in lung cancer patients. J Natl Cancer Inst (1998) 2.16
Human immunodeficiency virus type 1 integrase protein promotes reverse transcription through specific interactions with the nucleoprotein reverse transcription complex. J Virol (1999) 2.16
A novel TNF receptor family member binds TWEAK and is implicated in angiogenesis. Immunity (2001) 2.16
DNA array studies demonstrate convergent regulation of virulence factors by Cph1, Cph2, and Efg1 in Candida albicans. J Biol Chem (2001) 2.14
Function of hexameric RNA in packaging of bacteriophage phi 29 DNA in vitro. Mol Cell (1998) 2.13
Astrocyte-specific expression of activated p21-ras results in malignant astrocytoma formation in a transgenic mouse model of human gliomas. Cancer Res (2001) 2.13
Circulating FGF-21 levels in normal subjects and in newly diagnose patients with Type 2 diabetes mellitus. Exp Clin Endocrinol Diabetes (2007) 2.13
Specificity of DNA lesion bypass by the yeast DNA polymerase eta. J Biol Chem (2000) 2.12
Receptor endocytosis and dendrite reshaping in spinal neurons after somatosensory stimulation. Science (1995) 2.12
The human REV1 gene codes for a DNA template-dependent dCMP transferase. Nucleic Acids Res (1999) 2.10
Development of the human corpus callosum during childhood and adolescence: a longitudinal MRI study. Prog Neuropsychopharmacol Biol Psychiatry (1999) 2.10
The impact of boreal forest fire on climate warming. Science (2006) 2.08
Preferential incorporation of G opposite template T by the low-fidelity human DNA polymerase iota. Mol Cell Biol (2000) 2.08
Efficient high-frequency body coil for high-field MRI. Magn Reson Med (2004) 2.07
Error-prone lesion bypass by human DNA polymerase eta. Nucleic Acids Res (2000) 2.07
Hydrogen peroxide generated during cellular insulin stimulation is integral to activation of the distal insulin signaling cascade in 3T3-L1 adipocytes. J Biol Chem (2001) 2.06
Prediction of linear B-cell epitopes using amino acid pair antigenicity scale. Amino Acids (2007) 2.06
Upregulation of 78-kDa glucose-regulated protein in macrophages in peripheral joints of active ankylosing spondylitis. Scand J Rheumatol (2008) 2.06
Discovery of small-molecule inhibitors of Bcl-2 through structure-based computer screening. J Med Chem (2001) 2.06
The Dictyostelium CARMIL protein links capping protein and the Arp2/3 complex to type I myosins through their SH3 domains. J Cell Biol (2001) 2.05
Dhh1p, a putative RNA helicase, associates with the general transcription factors Pop2p and Ccr4p from Saccharomyces cerevisiae. Genetics (1998) 2.02
The function of adipocytes in the bone marrow stroma: an update. Bone (1996) 2.01
Loss of presenilin 1 is associated with enhanced beta-catenin signaling and skin tumorigenesis. Proc Natl Acad Sci U S A (2001) 2.00
Caspase-6 role in apoptosis of human neurons, amyloidogenesis, and Alzheimer's disease. J Biol Chem (1999) 2.00
Resistance of t(11;18) positive gastric mucosa-associated lymphoid tissue lymphoma to Helicobacter pylori eradication therapy. Lancet (2001) 1.97
Cloning of two candidate tumor suppressor genes within a 10 kb region on chromosome 13q14, frequently deleted in chronic lymphocytic leukemia. Oncogene (1997) 1.97
Insulin increases the association of Akt-2 with Glut4-containing vesicles. J Biol Chem (1998) 1.95
Defective granule exocytosis in Rab27a-deficient lymphocytes from Ashen mice. J Cell Biol (2001) 1.95
Suicide and social change in China. Cult Med Psychiatry (1999) 1.94
Mdm2 association with p53 targets its ubiquitination. Oncogene (1998) 1.94
Variation in the interleukin 4-receptor alpha gene confers susceptibility to asthma and atopy in ethnically diverse populations. Am J Hum Genet (2000) 1.94
Transforming growth factor-β regulates the sphere-initiating stem cell-like feature in breast cancer through miRNA-181 and ATM. Oncogene (2010) 1.92
Structure of human rhinovirus complexed with Fab fragments from a neutralizing antibody. J Virol (1993) 1.90
Peroxisome proliferator-activated receptor-gamma activation by thiazolidinediones induces adipogenesis in bone marrow stromal cells. Mol Pharmacol (1996) 1.90
Dictyostelium mutants lacking multiple classic myosin I isoforms reveal combinations of shared and distinct functions. J Cell Biol (1996) 1.89