Published in Amino Acids on January 26, 2007
Predicting linear B-cell epitopes using string kernels. J Mol Recognit (2008) 2.47
COBEpro: a novel system for predicting continuous B-cell epitopes. Protein Eng Des Sel (2008) 1.54
Identification of conformational B-cell Epitopes in an antigen from its primary sequence. Immunome Res (2010) 1.45
Reliable B cell epitope predictions: impacts of method development and improved benchmarking. PLoS Comput Biol (2012) 1.44
Improved method for linear B-cell epitope prediction using antigen's primary sequence. PLoS One (2013) 1.34
Predicting flexible length linear B-cell epitopes. Comput Syst Bioinformatics Conf (2008) 1.32
Structural analysis of B-cell epitopes in antibody:protein complexes. Mol Immunol (2012) 1.28
Recent advances in B-cell epitope prediction methods. Immunome Res (2010) 1.26
EPSVR and EPMeta: prediction of antigenic epitopes using support vector regression and multiple server results. BMC Bioinformatics (2010) 1.21
Prediction of conformational B-cell epitopes from 3D structures by random forests with a distance-based feature. BMC Bioinformatics (2011) 1.20
SVMTriP: a method to predict antigenic epitopes using support vector machine to integrate tri-peptide similarity and propensity. PLoS One (2012) 1.15
iRSpot-TNCPseAAC: identify recombination spots with trinucleotide composition and pseudo amino acid components. Int J Mol Sci (2014) 1.12
SVM-based prediction of linear B-cell epitopes using Bayes Feature Extraction. BMC Genomics (2010) 1.12
Prediction of protein domain with mRMR feature selection and analysis. PLoS One (2012) 1.12
Prediction of antigenic epitopes on protein surfaces by consensus scoring. BMC Bioinformatics (2009) 1.12
Removal of B cell epitopes as a practical approach for reducing the immunogenicity of foreign protein-based therapeutics. Adv Drug Deliv Rev (2009) 1.07
Conformational B-cell epitope prediction on antigen protein structures: a review of current algorithms and comparison with common binding site prediction methods. PLoS One (2013) 1.07
Developmental transcriptomic features of the carcinogenic liver fluke, Clonorchis sinensis. PLoS Negl Trop Dis (2011) 1.07
Prediction of B-cell linear epitopes with a combination of support vector machine classification and amino acid propensity identification. J Biomed Biotechnol (2011) 1.05
BEST: improved prediction of B-cell epitopes from antigen sequences. PLoS One (2012) 0.99
iOri-Human: identify human origin of replication by incorporating dinucleotide physicochemical properties into pseudo nucleotide composition. Oncotarget (2016) 0.97
iNR-Drug: predicting the interaction of drugs with nuclear receptors in cellular networking. Int J Mol Sci (2014) 0.96
Determinants of antigenicity and specificity in immune response for protein sequences. BMC Bioinformatics (2011) 0.94
Computational prediction of conformational B-cell epitopes from antigen primary structures by ensemble learning. PLoS One (2012) 0.93
Bioinformatics resources and tools for conformational B-cell epitope prediction. Comput Math Methods Med (2013) 0.92
Prediction of B-cell epitopes using evolutionary information and propensity scales. BMC Bioinformatics (2013) 0.91
iCar-PseCp: identify carbonylation sites in proteins by Monte Carlo sampling and incorporating sequence coupled effects into general PseAAC. Oncotarget (2016) 0.88
Targeted modifications in adeno-associated virus serotype 8 capsid improves its hepatic gene transfer efficiency in vivo. Hum Gene Ther Methods (2013) 0.87
An assessment on epitope prediction methods for protozoa genomes. BMC Bioinformatics (2012) 0.87
Identification of B-cell epitopes in an antigen for inducing specific class of antibodies. Biol Direct (2013) 0.87
Accurate prediction of immunogenic T-cell epitopes from epitope sequences using the genetic algorithm-based ensemble learning. PLoS One (2015) 0.87
Epitope predictions indicate the presence of two distinct types of epitope-antibody-reactivities determined by epitope profiling of intravenous immunoglobulins. PLoS One (2013) 0.87
Structure of allergens and structure based epitope predictions. Methods (2013) 0.86
Identification of B cell epitopes of alcohol dehydrogenase allergen of Curvularia lunata. PLoS One (2011) 0.85
iPhos-PseEn: identifying phosphorylation sites in proteins by fusing different pseudo components into an ensemble classifier. Oncotarget (2016) 0.84
Prediction of conformational epitopes with the use of a knowledge-based energy function and geometrically related neighboring residue characteristics. BMC Bioinformatics (2013) 0.84
iHyd-PseCp: Identify hydroxyproline and hydroxylysine in proteins by incorporating sequence-coupled effects into general PseAAC. Oncotarget (2016) 0.83
A genetic approach for building different alphabets for peptide and protein classification. BMC Bioinformatics (2008) 0.82
iROS-gPseKNC: Predicting replication origin sites in DNA by incorporating dinucleotide position-specific propensity into general pseudo nucleotide composition. Oncotarget (2016) 0.82
New approaches with different types of circulating cathodic antigen for the diagnosis of patients with low Schistosoma mansoni load. PLoS Negl Trop Dis (2013) 0.82
iRNA-AI: identifying the adenosine to inosine editing sites in RNA sequences. Oncotarget (2016) 0.81
Identification of amino acid propensities that are strong determinants of linear B-cell epitope using neural networks. PLoS One (2012) 0.81
Tertiary structure-based prediction of conformational B-cell epitopes through B factors. Bioinformatics (2014) 0.81
Positive-unlabeled learning for the prediction of conformational B-cell epitopes. BMC Bioinformatics (2015) 0.80
Identification of Novel Vaccine Candidates against Campylobacter through Reverse Vaccinology. J Immunol Res (2016) 0.80
Building classifier ensembles for B-cell epitope prediction. Methods Mol Biol (2014) 0.79
Prediction of linear B-cell epitopes of hepatitis C virus for vaccine development. BMC Med Genomics (2015) 0.78
In-silico screening, identification and validation of a novel vaccine candidate in the fight against Plasmodium falciparum. Parasitol Res (2017) 0.78
EPMLR: sequence-based linear B-cell epitope prediction method using multiple linear regression. BMC Bioinformatics (2014) 0.77
2L-piRNA: A Two-Layer Ensemble Classifier for Identifying Piwi-Interacting RNAs and Their Function. Mol Ther Nucleic Acids (2017) 0.76
Predicting linear B-cell epitopes using amino acid anchoring pair composition. BioData Min (2015) 0.76
Analysis of Conformational B-Cell Epitopes in the Antibody-Antigen Complex Using the Depth Function and the Convex Hull. PLoS One (2015) 0.76
A meta-learning approach for B-cell conformational epitope prediction. BMC Bioinformatics (2014) 0.76
The structure and dynamics of BmR1 protein from Brugia malayi: in silico approaches. Int J Mol Sci (2014) 0.76
In silico prediction of B- and T- cell epitope on Lassa virus proteins for peptide based subunit vaccine design. Adv Biomed Res (2015) 0.76
In Silico Study to Develop a Lectin-Like Protein from Mushroom Agaricus bisporus for Pharmaceutical Application. Sci Pharm (2016) 0.75
Immunoinformatics Features Linked to Leishmania Vaccine Development: Data Integration of Experimental and In Silico Studies. Int J Mol Sci (2017) 0.75
Immunoinformatics Approach in Designing Epitope-based Vaccine Against Meningitis-inducing Bacteria (Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae Type b). Drug Target Insights (2016) 0.75
Dimeric and Trimeric Fusion Proteins Generated with Fimbrial Adhesins of Uropathogenic Escherichia coli. Front Cell Infect Microbiol (2016) 0.75
Structural and thermodynamic insights into the recognition of native proteins by anti-peptide antibodies. J Mol Biol (2013) 0.75
iRNA-PseU: Identifying RNA pseudouridine sites. Mol Ther Nucleic Acids (2016) 0.75
A computational method for designing diverse linear epitopes including citrullinated peptides with desired binding affinities to intravenous immunoglobulin. BMC Bioinformatics (2016) 0.75
An Introduction to B-Cell Epitope Mapping and In Silico Epitope Prediction. J Immunol Res (2016) 0.75
iRNA-PseColl: Identifying the Occurrence Sites of Different RNA Modifications by Incorporating Collective Effects of Nucleotides into PseKNC. Mol Ther Nucleic Acids (2017) 0.75
SEPIa, a knowledge-driven algorithm for predicting conformational B-cell epitopes from the amino acid sequence. BMC Bioinformatics (2017) 0.75
Theoretical investigation on structural, functional and epitope of a 12 kDa excretory-secretory protein from Toxoplasma gondii. BMC Struct Biol (2012) 0.75
Classification epitopes in groups based on their protein family. BMC Bioinformatics (2015) 0.75
Inadequate Reference Datasets Biased toward Short Non-epitopes Confound B-cell Epitope Prediction. J Biol Chem (2016) 0.75
Selecting targets for the diagnosis of Schistosoma mansoni infection: An integrative approach using multi-omic and immunoinformatics data. PLoS One (2017) 0.75
DRREP: deep ridge regressed epitope predictor. BMC Genomics (2017) 0.75
PRmePRed: A protein arginine methylation prediction tool. PLoS One (2017) 0.75
In silico identification and validation of a novel hypothetical protein in Cryptosporidium hominis and virtual screening of inhibitors as therapeutics. Parasitol Res (2017) 0.75
Surface proteome mining for identification of potential vaccine candidates against Campylobacter jejuni: an in silico approach. Funct Integr Genomics (2016) 0.75
The complete genome sequence of the gram-positive bacterium Bacillus subtilis. Nature (1997) 33.47
Brain development during childhood and adolescence: a longitudinal MRI study. Nat Neurosci (1999) 18.57
Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell (1996) 16.73
Representing information in patient reports using natural language processing and the extensible markup language. J Am Med Inform Assoc (1999) 6.76
Ecological degradation in protected areas: the case of Wolong Nature Reserve for giant pandas. Science (2001) 6.52
Are Latinos less satisfied with communication by health care providers? J Gen Intern Med (1999) 5.26
A genomic screen of autism: evidence for a multilocus etiology. Am J Hum Genet (1999) 4.96
The PX domains of p47phox and p40phox bind to lipid products of PI(3)K. Nat Cell Biol (2001) 4.64
A fixative for intestinal parasites permitting the use of concentration and permanent staining procedures. Am J Clin Pathol (1977) 4.58
Tomotherapy: a new concept for the delivery of dynamic conformal radiotherapy. Med Phys (1994) 4.50
Circular intermediates of recombinant adeno-associated virus have defined structural characteristics responsible for long-term episomal persistence in muscle tissue. J Virol (1998) 4.17
Genome-wide association studies establish that human intelligence is highly heritable and polygenic. Mol Psychiatry (2011) 4.16
Estimation of pleiotropy between complex diseases using single-nucleotide polymorphism-derived genomic relationships and restricted maximum likelihood. Bioinformatics (2012) 3.97
Influenza neuraminidase inhibitors possessing a novel hydrophobic interaction in the enzyme active site: design, synthesis, and structural analysis of carbocyclic sialic acid analogues with potent anti-influenza activity. J Am Chem Soc (1997) 3.69
Glutamate release promotes growth of malignant gliomas. Nat Med (2001) 3.67
The induction of meningeal inflammation by components of the pneumococcal cell wall. J Infect Dis (1985) 3.66
Endosomal processing limits gene transfer to polarized airway epithelia by adeno-associated virus. J Clin Invest (2000) 3.57
Human cytomegalovirus with IE-2 (UL122) deleted fails to express early lytic genes. J Virol (2001) 3.50
Signaling and transcription in T helper development. Annu Rev Immunol (2000) 3.44
Solution structure of a 142-residue recombinant prion protein corresponding to the infectious fragment of the scrapie isoform. Proc Natl Acad Sci U S A (1997) 3.42
Ca2+ channel selectivity at a single locus for high-affinity Ca2+ interactions. Neuron (1995) 3.39
The CXC chemokine receptor 2, CXCR2, is the putative receptor for ELR+ CXC chemokine-induced angiogenic activity. J Immunol (2000) 3.26
A protein encoded within the Down syndrome critical region is enriched in striated muscles and inhibits calcineurin signaling. J Biol Chem (2000) 3.26
Regulation of CSF1 promoter by the SWI/SNF-like BAF complex. Cell (2001) 3.10
Assignment of the membrane attachment, DNA binding, and transcriptional activation domains of sterol regulatory element-binding protein-1 (SREBP-1). J Biol Chem (1994) 3.09
Induction of apoptosis by the low-affinity NGF receptor. Science (1993) 3.04
Virus-assisted mapping of neural inputs to a feeding center in the hypothalamus. Science (2001) 2.98
The BCL11 gene family: involvement of BCL11A in lymphoid malignancies. Blood (2001) 2.77
Dentinogenesis imperfecta 1 with or without progressive hearing loss is associated with distinct mutations in DSPP. Nat Genet (2001) 2.75
Retrohoming of a bacterial group II intron: mobility via complete reverse splicing, independent of homologous DNA recombination. Cell (1998) 2.74
Highly attenuated vaccine strains of simian immunodeficiency virus protect against vaginal challenge: inverse relationship of degree of protection with level of attenuation. J Virol (1999) 2.69
Myocyte-enriched calcineurin-interacting protein, MCIP1, inhibits cardiac hypertrophy in vivo. Proc Natl Acad Sci U S A (2001) 2.64
Direct binding of G-protein betagamma complex to voltage-dependent calcium channels. Nature (1997) 2.60
p300 is a component of an estrogen receptor coactivator complex. Proc Natl Acad Sci U S A (1996) 2.58
Autophagy and chemotherapy resistance: a promising therapeutic target for cancer treatment. Cell Death Dis (2013) 2.52
Cloning and characterization of alpha1H from human heart, a member of the T-type Ca2+ channel gene family. Circ Res (1998) 2.49
Observation of the spin-Seebeck effect in a ferromagnetic semiconductor. Nat Mater (2010) 2.44
Molecular subtyping of Treponema pallidum subspecies pallidum. Sex Transm Dis (1998) 2.44
PKA: a portrait of protein kinase dynamics. Biochim Biophys Acta (2004) 2.43
Evaluating the UMLS as a source of lexical knowledge for medical language processing. Proc AMIA Symp (2001) 2.41
A group II intron RNA is a catalytic component of a DNA endonuclease involved in intron mobility. Cell (1995) 2.37
MicroRNA miR-93 promotes tumor growth and angiogenesis by targeting integrin-β8. Oncogene (2010) 2.37
Apoptosis in a neonatal rat model of cerebral hypoxia-ischemia. Stroke (1998) 2.35
Evolution of an enzyme activity: crystallographic structure at 2-A resolution of cephalosporinase from the ampC gene of Enterobacter cloacae P99 and comparison with a class A penicillinase. Proc Natl Acad Sci U S A (1993) 2.34
Bleomycin-induced pulmonary fibrosis in fibrinogen-null mice. J Clin Invest (2000) 2.26
Induction of Alzheimer-like beta-amyloid immunoreactivity in the brains of rabbits with dietary cholesterol. Exp Neurol (1994) 2.25
Pattern of mutation in the genome of influenza A virus on adaptation to increased virulence in the mouse lung: identification of functional themes. Proc Natl Acad Sci U S A (2001) 2.25
Primary structure and expression of a sodium channel characteristic of denervated and immature rat skeletal muscle. Neuron (1990) 2.23
Evaluation of unpreserved and preserved stools for the detection and identification of intestinal parasites. Am J Clin Pathol (1974) 2.23
Functional RT and IN incorporated into HIV-1 particles independently of the Gag/Pol precursor protein. EMBO J (1997) 2.23
Cleavage of sterol regulatory element binding proteins (SREBPs) by CPP32 during apoptosis. EMBO J (1996) 2.22
Identification of a titratable lysine residue that determines sensitivity of kidney potassium channels (ROMK) to intracellular pH. EMBO J (1996) 2.21
Impaired wound healing in mouse models of diabetes is mediated by TNF-alpha dysregulation and associated with enhanced activation of forkhead box O1 (FOXO1). Diabetologia (2009) 2.18
Ginsenoside-Rd improves outcome of acute ischaemic stroke - a randomized, double-blind, placebo-controlled, multicenter trial. Eur J Neurol (2012) 2.18
Human immunodeficiency virus type 1 integrase protein promotes reverse transcription through specific interactions with the nucleoprotein reverse transcription complex. J Virol (1999) 2.16
A novel TNF receptor family member binds TWEAK and is implicated in angiogenesis. Immunity (2001) 2.16
Sustained growth and three-dimensional organization of primary mammary tumor epithelial cells embedded in collagen gels. Proc Natl Acad Sci U S A (1979) 2.15
Functional domains of the Rsp5 ubiquitin-protein ligase. Mol Cell Biol (1999) 2.15
Demonstration that mutation of the type II transforming growth factor beta receptor inactivates its tumor suppressor activity in replication error-positive colon carcinoma cells. J Biol Chem (1995) 2.15
DNA array studies demonstrate convergent regulation of virulence factors by Cph1, Cph2, and Efg1 in Candida albicans. J Biol Chem (2001) 2.14
Circulating FGF-21 levels in normal subjects and in newly diagnose patients with Type 2 diabetes mellitus. Exp Clin Endocrinol Diabetes (2007) 2.13
Cell separation by dielectrophoretic field-flow-fractionation. Anal Chem (2000) 2.13
MEK kinase 1 is critically required for c-Jun N-terminal kinase activation by proinflammatory stimuli and growth factor-induced cell migration. Proc Natl Acad Sci U S A (2000) 2.12
Receptor endocytosis and dendrite reshaping in spinal neurons after somatosensory stimulation. Science (1995) 2.12
Development of the human corpus callosum during childhood and adolescence: a longitudinal MRI study. Prog Neuropsychopharmacol Biol Psychiatry (1999) 2.10
Hormones and mammary carcinogenesis in mice, rats, and humans: a unifying hypothesis. Proc Natl Acad Sci U S A (1995) 2.09
The impact of boreal forest fire on climate warming. Science (2006) 2.08
Regulation of proprioceptive memory by subarachnoid regional anesthesia. Anesthesiology (2000) 2.08
Endocytosis and nuclear trafficking of adeno-associated virus type 2 are controlled by rac1 and phosphatidylinositol-3 kinase activation. J Virol (2000) 2.08
Efficient high-frequency body coil for high-field MRI. Magn Reson Med (2004) 2.07
Upregulation of 78-kDa glucose-regulated protein in macrophages in peripheral joints of active ankylosing spondylitis. Scand J Rheumatol (2008) 2.06
Mesenchymal to epithelial conversion in rat metanephros is induced by LIF. Cell (1999) 2.04
The removal of human breast cancer cells from hematopoietic CD34+ stem cells by dielectrophoretic field-flow-fractionation. J Hematother Stem Cell Res (1999) 2.03
Dhh1p, a putative RNA helicase, associates with the general transcription factors Pop2p and Ccr4p from Saccharomyces cerevisiae. Genetics (1998) 2.02
Expression of human tissue factor under the control of the mouse tissue factor promoter mediates normal hemostasis in knock-in mice. J Thromb Haemost (2007) 2.00
Caspase-6 role in apoptosis of human neurons, amyloidogenesis, and Alzheimer's disease. J Biol Chem (1999) 2.00
Progress in high resolution atomic force microscopy in biology. Q Rev Biophys (1995) 1.99
Regulation of Akt/PKB activation by tyrosine phosphorylation. J Biol Chem (2001) 1.98
Resistance of t(11;18) positive gastric mucosa-associated lymphoid tissue lymphoma to Helicobacter pylori eradication therapy. Lancet (2001) 1.97
Human insulin receptor monoclonal antibody undergoes high affinity binding to human brain capillaries in vitro and rapid transcytosis through the blood-brain barrier in vivo in the primate. Pharm Res (1995) 1.97
Characteristics of the in vitro assay of murine sarcoma virus (Moloney) and virus-infected cells. J Natl Cancer Inst (1968) 1.95
Insulin increases the association of Akt-2 with Glut4-containing vesicles. J Biol Chem (1998) 1.95
Suicide and social change in China. Cult Med Psychiatry (1999) 1.94
CD8+ T cell-dependent elimination of dendritic cells in vivo limits the induction of antitumor immunity. J Immunol (2000) 1.94
Mobility of yeast mitochondrial group II introns: engineering a new site specificity and retrohoming via full reverse splicing. Cell (1997) 1.91
Structure of human rhinovirus complexed with Fab fragments from a neutralizing antibody. J Virol (1993) 1.90
Architecture of a K+ channel inner pore revealed by stoichiometric covalent modification. Neuron (1999) 1.90
Risk factors for skin and soft-tissue abscesses among injection drug users: a case-control study. Clin Infect Dis (2001) 1.88
Effects of insulin on steady state kinetics of GLUT4 subcellular distribution in rat adipocytes. Evidence of constitutive GLUT4 recycling. J Biol Chem (1992) 1.86
Suppression of ocular neovascularization with siRNA targeting VEGF receptor 1. Gene Ther (2006) 1.86
Molecular subtyping of Treponema pallidum in an Arizona County with increasing syphilis morbidity: use of specimens from ulcers and blood. J Infect Dis (2001) 1.86
Estrogen metabolism and risk of breast cancer: a prospective study of the 2:16alpha-hydroxyestrone ratio in premenopausal and postmenopausal women. Epidemiology (2000) 1.86
Upregulation of lactate dehydrogenase A by ErbB2 through heat shock factor 1 promotes breast cancer cell glycolysis and growth. Oncogene (2009) 1.85
Decreased Ras-mitogen-activated protein kinase signaling may cause DNA hypomethylation in T lymphocytes from lupus patients. Arthritis Rheum (2001) 1.84
Patterns of status epilepticus-induced neuronal injury during development and long-term consequences. J Neurosci (1998) 1.83
PUMA is directly activated by NF-kappaB and contributes to TNF-alpha-induced apoptosis. Cell Death Differ (2009) 1.81
Cloning and expression of N-acetylglucosaminyltransferase I, the medial Golgi transferase that initiates complex N-linked carbohydrate formation. Proc Natl Acad Sci U S A (1990) 1.81
Nanometer size diesel exhaust particles are selectively toxic to dopaminergic neurons: the role of microglia, phagocytosis, and NADPH oxidase. FASEB J (2004) 1.79