Published in Nat Genet on December 17, 2001
Advances in autism genetics: on the threshold of a new neurobiology. Nat Rev Genet (2008) 12.18
LRRTM1 on chromosome 2p12 is a maternally suppressed gene that is associated paternally with handedness and schizophrenia. Mol Psychiatry (2007) 3.49
Reading skills in early readers: genetic and shared environmental influences. J Learn Disabil (2006) 3.14
Genome-wide analyses of human perisylvian cerebral cortical patterning. Proc Natl Acad Sci U S A (2007) 2.56
Genetic correlates of brain aging on MRI and cognitive test measures: a genome-wide association and linkage analysis in the Framingham Study. BMC Med Genet (2007) 2.51
DCDC2 is associated with reading disability and modulates neuronal development in the brain. Proc Natl Acad Sci U S A (2005) 2.35
Why are autism spectrum conditions more prevalent in males? PLoS Biol (2011) 2.35
The axon guidance receptor gene ROBO1 is a candidate gene for developmental dyslexia. PLoS Genet (2005) 2.02
A genomewide scan identifies two novel loci involved in specific language impairment. Am J Hum Genet (2002) 1.96
Strong evidence that KIAA0319 on chromosome 6p is a susceptibility gene for developmental dyslexia. Am J Hum Genet (2005) 1.93
A candidate gene for developmental dyslexia encodes a nuclear tetratricopeptide repeat domain protein dynamically regulated in brain. Proc Natl Acad Sci U S A (2003) 1.93
A major susceptibility locus for specific language impairment is located on 13q21. Am J Hum Genet (2002) 1.79
A 77-kilobase region of chromosome 6p22.2 is associated with dyslexia in families from the United Kingdom and from the United States. Am J Hum Genet (2004) 1.76
Longitudinal genetic analysis of early reading: The Western Reserve Reading Project. Read Writ (2007) 1.75
Genetic and Environmental Effects of Serial Naming and Phonological Awareness on Early Reading Outcomes. J Educ Psychol (2006) 1.75
Investigation of dyslexia and SLI risk variants in reading- and language-impaired subjects. Behav Genet (2010) 1.67
Highly significant linkage to the SLI1 locus in an expanded sample of individuals affected by specific language impairment. Am J Hum Genet (2004) 1.63
A genomewide scan for loci involved in attention-deficit/hyperactivity disorder. Am J Hum Genet (2002) 1.63
Use of multivariate linkage analysis for dissection of a complex cognitive trait. Am J Hum Genet (2003) 1.62
Refinement of the 6p21.3 quantitative trait locus influencing dyslexia: linkage and association analyses. Hum Genet (2004) 1.51
A whole-genome scan and fine-mapping linkage study of auditory-visual synesthesia reveals evidence of linkage to chromosomes 2q24, 5q33, 6p12, and 12p12. Am J Hum Genet (2009) 1.50
A genomewide linkage screen for relative hand skill in sibling pairs. Am J Hum Genet (2002) 1.46
Genetics of developmental dyslexia. Eur Child Adolesc Psychiatry (2009) 1.38
Pleiotropic effects of a chromosome 3 locus on speech-sound disorder and reading. Am J Hum Genet (2004) 1.36
Evidence for linkage and association with reading disability on 6p21.3-22. Am J Hum Genet (2002) 1.31
Neuropsychological endophenotype approach to genome-wide linkage analysis identifies susceptibility loci for ADHD on 2q21.1 and 13q12.11. Am J Hum Genet (2008) 1.23
A common variant associated with dyslexia reduces expression of the KIAA0319 gene. PLoS Genet (2009) 1.20
Combined analysis of genome scans of dutch and finnish families reveals a susceptibility locus for high-density lipoprotein cholesterol on chromosome 16q. Am J Hum Genet (2003) 1.19
PCSK6 is associated with handedness in individuals with dyslexia. Hum Mol Genet (2010) 1.14
The genetics of reading disabilities: from phenotypes to candidate genes. Front Psychol (2013) 1.12
Genome-wide linkage scan for loci of musical aptitude in Finnish families: evidence for a major locus at 4q22. J Med Genet (2008) 1.11
Association of reading disabilities with regions marked by acetylated H3 histones in KIAA0319. Am J Med Genet B Neuropsychiatr Genet (2010) 1.05
Genetics of dyslexia: the evolving landscape. J Med Genet (2007) 0.99
Defining the biological bases of individual differences in musicality. Philos Trans R Soc Lond B Biol Sci (2015) 0.97
Confirmatory evidence for linkage of relative hand skill to 2p12-q11. Am J Hum Genet (2003) 0.97
A transcription map of the 6p22.3 reading disability locus identifying candidate genes. BMC Genomics (2003) 0.96
Genomewide scan for real-word reading subphenotypes of dyslexia: novel chromosome 13 locus and genetic complexity. Am J Med Genet B Neuropsychiatr Genet (2006) 0.96
Globularity and language-readiness: generating new predictions by expanding the set of genes of interest. Front Psychol (2014) 0.94
Prevalence and associated risk factors of dyslexic children in a middle-sized city of China: a cross-sectional study. PLoS One (2013) 0.94
Common variation near ROBO2 is associated with expressive vocabulary in infancy. Nat Commun (2014) 0.94
Pleiotropic effects of DCDC2 and DYX1C1 genes on language and mathematics traits in nuclear families of developmental dyslexia. Behav Genet (2010) 0.93
The KIAA0319-like (KIAA0319L) gene on chromosome 1p34 as a candidate for reading disabilities. J Neurogenet (2008) 0.93
Genomewide scan identifies susceptibility locus for dyslexia on Xq27 in an extended Dutch family. J Med Genet (2004) 0.92
Identification of candidate genes for dyslexia susceptibility on chromosome 18. PLoS One (2010) 0.92
Exploiting human anatomical variability as a link between genome and cognome. Genes Brain Behav (2006) 0.91
Genome scan of a nonword repetition phenotype in families with dyslexia: evidence for multiple loci. Behav Genet (2008) 0.90
Linkage analyses of chromosomal region 18p11-q12 in dyslexia. J Neural Transm (Vienna) (2005) 0.89
The first candidate gene for dyslexia: Turning the page of a new chapter of research. Proc Natl Acad Sci U S A (2003) 0.89
Genome scan for spelling deficits: effects of verbal IQ on models of transmission and trait gene localization. Behav Genet (2010) 0.88
Dyslexia: the Role of Vision and Visual Attention. Curr Dev Disord Rep (2014) 0.88
In search of the perfect phenotype: an analysis of linkage and association studies of reading and reading-related processes. Behav Genet (2011) 0.87
Literacy outcomes of children with early childhood speech sound disorders: impact of endophenotypes. J Speech Lang Hear Res (2011) 0.87
Reading and language disorders: the importance of both quantity and quality. Genes (Basel) (2014) 0.86
Genome scan for cognitive trait loci of dyslexia: Rapid naming and rapid switching of letters, numbers, and colors. Am J Med Genet B Neuropsychiatr Genet (2014) 0.83
Fine mapping of the 2p11 dyslexia locus and exclusion of TACR1 as a candidate gene. Hum Genet (2004) 0.83
Genetic pleiotropy explains associations between musical auditory discrimination and intelligence. PLoS One (2014) 0.82
Language Impairments in ASD Resulting from a Failed Domestication of the Human Brain. Front Neurosci (2016) 0.80
The human lexinome: genes of language and reading. J Commun Disord (2008) 0.79
Allelic variants of DYX1C1 are not associated with dyslexia in India. Indian J Hum Genet (2008) 0.78
Approach to epigenetic analysis in language disorders. J Neurodev Disord (2011) 0.78
DCDC2 gene polymorphisms are associated with developmental dyslexia in Chinese Uyghur children. Neural Regen Res (2017) 0.75
Next-generation DNA sequencing identifies novel gene variants and pathways involved in specific language impairment. Sci Rep (2017) 0.75
Genomic sequencing of a dyslexia susceptibility haplotype encompassing ROBO1. J Neurodev Disord (2016) 0.75
A case of Bilateral Perisylvian Syndrome with reading disability. Cortex (2016) 0.75
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
Finding the missing heritability of complex diseases. Nature (2009) 67.95
Merlin--rapid analysis of dense genetic maps using sparse gene flow trees. Nat Genet (2001) 53.16
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science (2007) 37.88
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. Science (2007) 32.97
Genome-wide association studies for complex traits: consensus, uncertainty and challenges. Nat Rev Genet (2008) 30.94
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. Nat Genet (2008) 30.20
Large recurrent microdeletions associated with schizophrenia. Nature (2008) 20.25
Genome-wide detection and characterization of positive selection in human populations. Nature (2007) 17.27
Replicating genotype-phenotype associations. Nature (2007) 16.11
The effects of human population structure on large genetic association studies. Nat Genet (2004) 14.88
Genome-wide strategies for detecting multiple loci that influence complex diseases. Nat Genet (2005) 14.88
Functional impact of global rare copy number variation in autism spectrum disorders. Nature (2010) 14.66
Mapping autism risk loci using genetic linkage and chromosomal rearrangements. Nat Genet (2007) 14.05
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nat Genet (2007) 12.62
Evaluating coverage of genome-wide association studies. Nat Genet (2006) 11.40
Meta-analysis and imputation refines the association of 15q25 with smoking quantity. Nat Genet (2010) 8.55
A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21. Nat Genet (2007) 8.50
Thousands of chemical starting points for antimalarial lead identification. Nature (2010) 8.28
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet (2013) 8.02
An abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people. Science (2012) 7.94
Validity of the executive function theory of attention-deficit/hyperactivity disorder: a meta-analytic review. Biol Psychiatry (2005) 7.90
A first-generation linkage disequilibrium map of human chromosome 22. Nature (2002) 7.03
Molecular evolution of FOXP2, a gene involved in speech and language. Nature (2002) 5.89
Two-stage two-locus models in genome-wide association. PLoS Genet (2006) 5.60
The complex interplay among factors that influence allelic association. Nat Rev Genet (2004) 5.26
A genome-wide investigation of SNPs and CNVs in schizophrenia. PLoS Genet (2009) 5.01
A functional genetic link between distinct developmental language disorders. N Engl J Med (2008) 4.99
Linkage disequilibrium mapping via cladistic analysis of single-nucleotide polymorphism haplotypes. Am J Hum Genet (2004) 4.44
Evaluating the effects of imputation on the power, coverage, and cost efficiency of genome-wide SNP platforms. Am J Hum Genet (2008) 4.28
Common variants at five new loci associated with early-onset inflammatory bowel disease. Nat Genet (2009) 3.82
Venezuelan kindreds reveal that genetic and environmental factors modulate Huntington's disease age of onset. Proc Natl Acad Sci U S A (2004) 3.73
Data quality control in genetic case-control association studies. Nat Protoc (2010) 3.68
Measures of human population structure show heterogeneity among genomic regions. Genome Res (2005) 3.68
Investigation of the fine structure of European populations with applications to disease association studies. Eur J Hum Genet (2008) 3.65
Identification of FOXP2 truncation as a novel cause of developmental speech and language deficits. Am J Hum Genet (2005) 3.50
Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry. Proc Natl Acad Sci U S A (2009) 3.49
A genome-wide scan for common alleles affecting risk for autism. Hum Mol Genet (2010) 3.42
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. Nat Genet (2011) 3.03
Validity of DSM-IV attention deficit/hyperactivity disorder symptom dimensions and subtypes. J Abnorm Psychol (2012) 2.86
A high-resolution linkage-disequilibrium map of the human major histocompatibility complex and first generation of tag single-nucleotide polymorphisms. Am J Hum Genet (2005) 2.85
The impact of SNP density on fine-scale patterns of linkage disequilibrium. Hum Mol Genet (2004) 2.78
Genetic susceptibility to cancer: the role of polymorphisms in candidate genes. JAMA (2008) 2.73
An evaluation of HapMap sample size and tagging SNP performance in large-scale empirical and simulated data sets. Nat Genet (2005) 2.66
Genetic and functional analyses of SHANK2 mutations suggest a multiple hit model of autism spectrum disorders. PLoS Genet (2012) 2.65
GOLDsurfer: three dimensional display of linkage disequilibrium. Bioinformatics (2004) 2.61
Genetic and environmental influences on individual differences in printed word recognition. J Exp Child Psychol (2003) 2.59
Efficient selective screening of haplotype tag SNPs. Bioinformatics (2003) 2.57
FOXP2 expression during brain development coincides with adult sites of pathology in a severe speech and language disorder. Brain (2003) 2.55
A multiple deficit model of reading disability and attention-deficit/hyperactivity disorder: searching for shared cognitive deficits. J Child Psychol Psychiatry (2010) 2.52
An 18-kDa translocator protein (TSPO) polymorphism explains differences in binding affinity of the PET radioligand PBR28. J Cereb Blood Flow Metab (2011) 2.52
Use of genome-wide association studies for drug repositioning. Nat Biotechnol (2012) 2.51
The impact of genotyping error on haplotype reconstruction and frequency estimation. Eur J Hum Genet (2002) 2.51
Neuropsychological analyses of comorbidity between reading disability and attention deficit hyperactivity disorder: in search of the common deficit. Dev Neuropsychol (2005) 2.50
Individual common variants exert weak effects on the risk for autism spectrum disorderspi. Hum Mol Genet (2012) 2.46
Designing candidate gene and genome-wide case-control association studies. Nat Protoc (2007) 2.42
DCDC2 is associated with reading disability and modulates neuronal development in the brain. Proc Natl Acad Sci U S A (2005) 2.35
Genetic and Environmental Influences on Aspects of Literacy and Language in Early Childhood: Continuity and Change from Preschool to Grade 2. J Neurolinguistics (2009) 2.18
The chromosome 6p22 haplotype associated with dyslexia reduces the expression of KIAA0319, a novel gene involved in neuronal migration. Hum Mol Genet (2006) 2.14
A 15q13.3 microdeletion segregating with autism. Eur J Hum Genet (2008) 2.12
Costs of ABO incompatible living donor transplantation are justified. Transplantation (2006) 2.07
Characterization of a family with rare deletions in CNTNAP5 and DOCK4 suggests novel risk loci for autism and dyslexia. Biol Psychiatry (2010) 2.07
The portability of tagSNPs across populations: a worldwide survey. Genome Res (2006) 1.99
Developmental dyslexia: genetic dissection of a complex cognitive trait. Nat Rev Neurosci (2002) 1.97
Guidelines for genotyping in genomewide linkage studies: single-nucleotide-polymorphism maps versus microsatellite maps. Am J Hum Genet (2004) 1.94
The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data. Brain Imaging Behav (2014) 1.90
Basic statistical analysis in genetic case-control studies. Nat Protoc (2011) 1.86
Developmental dyslexia. Lancet (2012) 1.86
QTL analysis of multiple behavioral measures of anxiety in mice. Behav Genet (2004) 1.79
Performance on Cambridge Neuropsychological Test Automated Battery subtests sensitive to frontal lobe function in people with autistic disorder: evidence from the Collaborative Programs of Excellence in Autism network. J Autism Dev Disord (2004) 1.79
A 77-kilobase region of chromosome 6p22.2 is associated with dyslexia in families from the United Kingdom and from the United States. Am J Hum Genet (2004) 1.76
Inflammatory bowel disease is associated with a TNF polymorphism that affects an interaction between the OCT1 and NF(-kappa)B transcription factors. Hum Mol Genet (2002) 1.76
Disruption at the PTCHD1 Locus on Xp22.11 in Autism spectrum disorder and intellectual disability. Sci Transl Med (2010) 1.75
Functional epistasis on a common MHC haplotype associated with multiple sclerosis. Nature (2006) 1.75
Etiology and neuropsychology of comorbidity between RD and ADHD: the case for multiple-deficit models. Cortex (2010) 1.75
A comparison of linkage disequilibrium patterns and estimated population recombination rates across multiple populations. Am J Hum Genet (2005) 1.75
Response to early literacy instruction in the United States, Australia, and Scandinavia: A behavioral-genetic analysis. Learn Individ Differ (2008) 1.73
TUCAN (CARD8) genetic variants and inflammatory bowel disease. Gastroenterology (2006) 1.73
The genetic lexicon of dyslexia. Annu Rev Genomics Hum Genet (2007) 1.72