Published in Proc Natl Acad Sci U S A on May 19, 2011
Outcome of the First wwPDB Hybrid/Integrative Methods Task Force Workshop. Structure (2015) 2.93
Photophysics of fluorescent probes for single-molecule biophysics and super-resolution imaging. Annu Rev Phys Chem (2012) 2.19
A toolkit and benchmark study for FRET-restrained high-precision structural modeling. Nat Methods (2012) 1.56
How random are intrinsically disordered proteins? A small angle scattering perspective. Curr Protein Pept Sci (2012) 1.37
Structural characterization by cross-linking reveals the detailed architecture of a coatomer-related heptameric module from the nuclear pore complex. Mol Cell Proteomics (2014) 1.23
The ESCRT machinery: from the plasma membrane to endosomes and back again. Crit Rev Biochem Mol Biol (2014) 1.12
Solution structure of the ESCRT-I and -II supercomplex: implications for membrane budding and scission. Structure (2012) 1.06
Structure of cellular ESCRT-III spirals and their relationship to HIV budding. Elife (2014) 1.04
Structural refinement from restrained-ensemble simulations based on EPR/DEER data: application to T4 lysozyme. J Phys Chem B (2013) 1.04
Restrained-ensemble molecular dynamics simulations based on distance histograms from double electron-electron resonance spectroscopy. J Phys Chem B (2013) 1.04
Helical membrane protein conformations and their environment. Eur Biophys J (2013) 0.99
Methods for SAXS-based structure determination of biomolecular complexes. Adv Mater (2014) 0.92
Endosomal sorting complex required for transport (ESCRT) complexes induce phase-separated microdomains in supported lipid bilayers. J Biol Chem (2012) 0.91
Uncertainty in integrative structural modeling. Curr Opin Struct Biol (2014) 0.91
Wrapping up the bad news: HIV assembly and release. Retrovirology (2013) 0.88
Membrane-elasticity model of Coatless vesicle budding induced by ESCRT complexes. PLoS Comput Biol (2012) 0.87
Wide-angle X-ray solution scattering for protein-ligand binding: multivariate curve resolution with Bayesian confidence intervals. Biophys J (2013) 0.87
Solution structure of the Atg1 complex: implications for the architecture of the phagophore assembly site. Structure (2015) 0.86
Identifying and quantitating conformational exchange in membrane proteins using site-directed spin labeling. Acc Chem Res (2014) 0.84
Mapping membrane protein structure with fluorescence. Curr Opin Struct Biol (2012) 0.82
Combination of X-ray crystallography, SAXS and DEER to obtain the structure of the FnIII-3,4 domains of integrin α6β4. Acta Crystallogr D Biol Crystallogr (2015) 0.80
Pkh1/2-dependent phosphorylation of Vps27 regulates ESCRT-I recruitment to endosomes. Mol Biol Cell (2012) 0.79
Bayesian analysis of individual electron microscopy images: towards structures of dynamic and heterogeneous biomolecular assemblies. J Struct Biol (2013) 0.78
Taking the pulse of protein interactions by EPR spectroscopy. Biophys J (2012) 0.76
Investigating the Role of Large-Scale Domain Dynamics in Protein-Protein Interactions. Front Mol Biosci (2016) 0.75
MESMER: minimal ensemble solutions to multiple experimental restraints. Bioinformatics (2015) 0.75
Using chemical shifts to generate structural ensembles for intrinsically disordered proteins with converged distributions of secondary structure. Intrinsically Disord Proteins (2015) 0.75
The solution structure of the transducin-α-uncoordinated 119 protein complex suggests occlusion of the Gβ₁γ₁-binding sites. FEBS J (2014) 0.75
Theoretical modeling of multiprotein complexes by iSPOT: Integration of small-angle X-ray scattering, hydroxyl radical footprinting, and computational docking. J Struct Biol (2016) 0.75
Tsg101 and the vacuolar protein sorting pathway are essential for HIV-1 budding. Cell (2001) 12.00
Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I. Cell (2001) 9.08
X-ray solution scattering (SAXS) combined with crystallography and computation: defining accurate macromolecular structures, conformations and assemblies in solution. Q Rev Biophys (2007) 9.07
HIV-1 and Ebola virus encode small peptide motifs that recruit Tsg101 to sites of particle assembly to facilitate egress. Nat Med (2001) 8.38
The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins. Nature (2009) 6.99
Parallels between cytokinesis and retroviral budding: a role for the ESCRT machinery. Science (2007) 6.13
Tsg101, a homologue of ubiquitin-conjugating (E2) enzymes, binds the L domain in HIV type 1 Pr55(Gag). Proc Natl Acad Sci U S A (2001) 5.83
Human ESCRT and ALIX proteins interact with proteins of the midbody and function in cytokinesis. EMBO J (2007) 5.31
Membrane budding and scission by the ESCRT machinery: it's all in the neck. Nat Rev Mol Cell Biol (2010) 4.29
Overexpression of the N-terminal domain of TSG101 inhibits HIV-1 budding by blocking late domain function. Proc Natl Acad Sci U S A (2002) 4.14
Molecular mechanism of multivesicular body biogenesis by ESCRT complexes. Nature (2010) 4.05
Recent advances and applications of site-directed spin labeling. Curr Opin Struct Biol (2006) 3.12
Rotamer libraries of spin labelled cysteines for protein studies. Phys Chem Chem Phys (2010) 2.78
Structure of the Tsg101 UEV domain in complex with the PTAP motif of the HIV-1 p6 protein. Nat Struct Biol (2002) 2.66
Characterizing the unfolded states of proteins using single-molecule FRET spectroscopy and molecular simulations. Proc Natl Acad Sci U S A (2007) 2.65
ESCRT-I core and ESCRT-II GLUE domain structures reveal role for GLUE in linking to ESCRT-I and membranes. Cell (2006) 2.38
SAXS ensemble refinement of ESCRT-III CHMP3 conformational transitions. Structure (2011) 2.24
Did2 coordinates Vps4-mediated dissociation of ESCRT-III from endosomes. J Cell Biol (2006) 2.24
Midbody targeting of the ESCRT machinery by a noncanonical coiled coil in CEP55. Science (2008) 2.23
Molecular architecture and functional model of the complete yeast ESCRT-I heterotetramer. Cell (2007) 2.21
Ubiquitin recognition by the human TSG101 protein. Mol Cell (2004) 2.17
Refined solution structure of the 82-kDa enzyme malate synthase G from joint NMR and synchrotron SAXS restraints. J Biomol NMR (2007) 2.00
Coarse-grained models for simulations of multiprotein complexes: application to ubiquitin binding. J Mol Biol (2007) 1.74
Structural insight into the ESCRT-I/-II link and its role in MVB trafficking. EMBO J (2007) 1.60
Structural insights into endosomal sorting complex required for transport (ESCRT-I) recognition of ubiquitinated proteins. J Biol Chem (2004) 1.57
Structural and functional organization of the ESCRT-I trafficking complex. Cell (2006) 1.51
No strings attached: the ESCRT machinery in viral budding and cytokinesis. J Cell Sci (2009) 1.50
Unfolded protein and peptide dynamics investigated with single-molecule FRET and correlation spectroscopy from picoseconds to seconds. J Phys Chem B (2008) 1.48
ESCRT ubiquitin-binding domains function cooperatively during MVB cargo sorting. J Cell Biol (2009) 1.47
The crystal structure of the C-terminal domain of Vps28 reveals a conserved surface required for Vps20 recruitment. Traffic (2006) 1.39
Inhibition of HIV budding by a genetically selected cyclic peptide targeting the Gag-TSG101 interaction. ACS Chem Biol (2008) 1.23
Three-dimensional molecular modeling with single molecule FRET. J Struct Biol (2010) 1.20
Crystallographic and functional analysis of the ESCRT-I /HIV-1 Gag PTAP interaction. Structure (2010) 1.04
Probing the free-energy surface for protein folding with single-molecule fluorescence spectroscopy. Nature (2002) 6.92
The protein folding 'speed limit'. Curr Opin Struct Biol (2004) 6.19
Membrane scission by the ESCRT-III complex. Nature (2009) 4.66
Protein folding studied by single-molecule FRET. Curr Opin Struct Biol (2008) 4.33
Molecular mechanism of multivesicular body biogenesis by ESCRT complexes. Nature (2010) 4.05
Intrinsic rates and activation free energies from single-molecule pulling experiments. Phys Rev Lett (2006) 4.04
Retromer. Curr Opin Cell Biol (2008) 3.89
Theory, analysis, and interpretation of single-molecule force spectroscopy experiments. Proc Natl Acad Sci U S A (2008) 3.51
Structural mechanism for sterol sensing and transport by OSBP-related proteins. Nature (2005) 3.22
Optimized molecular dynamics force fields applied to the helix-coil transition of polypeptides. J Phys Chem B (2009) 3.17
Are current molecular dynamics force fields too helical? Biophys J (2008) 3.13
Reaction coordinates and rates from transition paths. Proc Natl Acad Sci U S A (2005) 3.12
Recent advances and applications of site-directed spin labeling. Curr Opin Struct Biol (2006) 3.12
Experimental tests of villin subdomain folding simulations. J Mol Biol (2003) 3.08
Single-molecule measurement of protein folding kinetics. Science (2003) 3.08
Polyproline and the "spectroscopic ruler" revisited with single-molecule fluorescence. Proc Natl Acad Sci U S A (2005) 3.01
Coarse master equations for peptide folding dynamics. J Phys Chem B (2008) 3.01
Structural basis for ubiquitin recognition and autoubiquitination by Rabex-5. Nat Struct Mol Biol (2006) 2.85
A ubiquitin-binding motif required for intramolecular monoubiquitylation, the CUE domain. EMBO J (2003) 2.73
Sub-microsecond protein folding. J Mol Biol (2006) 2.72
Electrostatic sequestration of PIP2 on phospholipid membranes by basic/aromatic regions of proteins. Biophys J (2004) 2.66
Characterizing the unfolded states of proteins using single-molecule FRET spectroscopy and molecular simulations. Proc Natl Acad Sci U S A (2007) 2.65
Water in nonpolar confinement: from nanotubes to proteins and beyond. Annu Rev Phys Chem (2008) 2.57
Structure and catalytic mechanism of a SET domain protein methyltransferase. Cell (2002) 2.45
Dynamics of endosomal sorting complex required for transport (ESCRT) machinery during cytokinesis and its role in abscission. Proc Natl Acad Sci U S A (2011) 2.45
Osmotic water transport through carbon nanotube membranes. Proc Natl Acad Sci U S A (2003) 2.41
High-resolution x-ray crystal structures of the villin headpiece subdomain, an ultrafast folding protein. Proc Natl Acad Sci U S A (2005) 2.37
Experimental determination of upper bound for transition path times in protein folding from single-molecule photon-by-photon trajectories. Proc Natl Acad Sci U S A (2009) 2.29
Structural basis for endosomal targeting by the Bro1 domain. Dev Cell (2005) 2.28
Water-gated mechanism of proton translocation by cytochrome c oxidase. Biochim Biophys Acta (2003) 2.26
Functional architecture of the retromer cargo-recognition complex. Nature (2007) 2.26
Mechanism of ubiquitin recognition by the CUE domain of Vps9p. Cell (2003) 2.25
SAXS ensemble refinement of ESCRT-III CHMP3 conformational transitions. Structure (2011) 2.24
Midbody targeting of the ESCRT machinery by a noncanonical coiled coil in CEP55. Science (2008) 2.23
Molecular architecture and functional model of the complete yeast ESCRT-I heterotetramer. Cell (2007) 2.21
Crystal structure and allosteric activation of protein kinase C βII. Cell (2011) 2.19
Structural basis for midbody targeting of spastin by the ESCRT-III protein CHMP1B. Nat Struct Mol Biol (2008) 2.18
The retromer subunit Vps26 has an arrestin fold and binds Vps35 through its C-terminal domain. Nat Struct Mol Biol (2006) 2.09
Structural basis for acidic-cluster-dileucine sorting-signal recognition by VHS domains. Nature (2002) 2.09
Beyond Tsg101: the role of Alix in 'ESCRTing' HIV-1. Nat Rev Microbiol (2007) 2.08
Binding-induced folding of a natively unstructured transcription factor. PLoS Comput Biol (2008) 2.04
Nonvesicular sterol movement from plasma membrane to ER requires oxysterol-binding protein-related proteins and phosphoinositides. J Cell Biol (2006) 2.04
Single-molecule fluorescence experiments determine protein folding transition path times. Science (2012) 2.00
Molecular dynamics simulations of Alzheimer's beta-amyloid protofilaments. J Mol Biol (2005) 1.99
Sorting of the Alzheimer's disease amyloid precursor protein mediated by the AP-4 complex. Dev Cell (2010) 1.98
Reactive flux and folding pathways in network models of coarse-grained protein dynamics. J Chem Phys (2009) 1.93
NMR solution structure of the integral membrane enzyme DsbB: functional insights into DsbB-catalyzed disulfide bond formation. Mol Cell (2008) 1.92
Cooperative water filling of a nonpolar protein cavity observed by high-pressure crystallography and simulation. Proc Natl Acad Sci U S A (2005) 1.91
Chemical, physical, and theoretical kinetics of an ultrafast folding protein. Proc Natl Acad Sci U S A (2008) 1.90
Downregulation of CD4 by human immunodeficiency virus type 1 Nef is dependent on clathrin and involves direct interaction of Nef with the AP2 clathrin adaptor. J Virol (2007) 1.90
Syp1 is a conserved endocytic adaptor that contains domains involved in cargo selection and membrane tubulation. EMBO J (2009) 1.88
Slow protein conformational dynamics from multiple experimental structures: the helix/sheet transition of arc repressor. Structure (2005) 1.86
Proton transport through water-filled carbon nanotubes. Phys Rev Lett (2003) 1.86
Structure of a lipid droplet protein; the PAT family member TIP47. Structure (2004) 1.85
Effect of flexibility and cis residues in single-molecule FRET studies of polyproline. Proc Natl Acad Sci U S A (2007) 1.81
Structure of the ESCRT-II endosomal trafficking complex. Nature (2004) 1.80
Structural mechanism for lipid activation of the Rac-specific GAP, beta2-chimaerin. Cell (2004) 1.79
Extracting kinetics from single-molecule force spectroscopy: nanopore unzipping of DNA hairpins. Biophys J (2007) 1.78
Electric field and temperature effects on water in the narrow nonpolar pores of carbon nanotubes. J Chem Phys (2004) 1.78
Two-dimensional infrared spectroscopy of antiparallel beta-sheet secondary structure. J Am Chem Soc (2004) 1.75
Coarse-grained models for simulations of multiprotein complexes: application to ubiquitin binding. J Mol Biol (2007) 1.74
Coordinate-dependent diffusion in protein folding. Proc Natl Acad Sci U S A (2009) 1.73
Mechanism of multiple lysine methylation by the SET domain enzyme Rubisco LSMT. Nat Struct Biol (2003) 1.73
Pore opening and closing of a pentameric ligand-gated ion channel. Proc Natl Acad Sci U S A (2010) 1.71
Measuring internal friction of an ultrafast-folding protein. Proc Natl Acad Sci U S A (2008) 1.69
Structural basis for viral late-domain binding to Alix. Nat Struct Mol Biol (2007) 1.69
Peptide loop-closure kinetics from microsecond molecular dynamics simulations in explicit solvent. J Am Chem Soc (2002) 1.69
Single-file transport of water molecules through a carbon nanotube. Phys Rev Lett (2002) 1.67
Coarse master equation from Bayesian analysis of replica molecular dynamics simulations. J Phys Chem B (2005) 1.64
Water clusters in nonpolar cavities. Proc Natl Acad Sci U S A (2004) 1.59
Nucleic acid transport through carbon nanotube membranes. Proc Natl Acad Sci U S A (2004) 1.58
Membrane orientation and position of the C2 domain from cPLA2 by site-directed spin labeling. Biochemistry (2002) 1.57
Dynamic structure of lipid-bound synaptobrevin suggests a nucleation-propagation mechanism for trans-SNARE complex formation. Proc Natl Acad Sci U S A (2009) 1.57
Position of synaptotagmin I at the membrane interface: cooperative interactions of tandem C2 domains. Biochemistry (2006) 1.54
Diffusive model of protein folding dynamics with Kramers turnover in rate. Phys Rev Lett (2006) 1.53
Convergence and error estimation in free energy calculations using the weighted histogram analysis method. J Comput Chem (2011) 1.52
Structural and functional organization of the ESCRT-I trafficking complex. Cell (2006) 1.51
Structure and function of the ESCRT-II-III interface in multivesicular body biogenesis. Dev Cell (2009) 1.50
Diffusion and electrophoretic mobility of single-stranded RNA from molecular dynamics simulations. Biophys J (2004) 1.49
Membrane-bound orientation and position of the synaptotagmin I C2A domain by site-directed spin labeling. Biochemistry (2003) 1.47
Watching a signaling protein function in real time via 100-ps time-resolved Laue crystallography. Proc Natl Acad Sci U S A (2012) 1.46
Pulling direction as a reaction coordinate for the mechanical unfolding of single molecules. J Phys Chem B (2008) 1.46
Normalization of nomenclature for peptide motifs as ligands of modular protein domains. FEBS Lett (2002) 1.46
Peptide folding kinetics from replica exchange molecular dynamics. Phys Rev E Stat Nonlin Soft Matter Phys (2008) 1.45
An Alix fragment potently inhibits HIV-1 budding: characterization of binding to retroviral YPXL late domains. J Biol Chem (2006) 1.44
Ion transport through membrane-spanning nanopores studied by molecular dynamics simulations and continuum electrostatics calculations. Biophys J (2005) 1.43
Catalytic mechanism of RNA backbone cleavage by ribonuclease H from quantum mechanics/molecular mechanics simulations. J Am Chem Soc (2011) 1.42
Determination of ultrafast protein folding rates from loop formation dynamics. J Mol Biol (2005) 1.42
Amide I two-dimensional infrared spectroscopy of proteins. Acc Chem Res (2008) 1.41
The ESCRT machinery at a glance. J Cell Sci (2009) 1.41
Static and dynamic correlations in water at hydrophobic interfaces. Proc Natl Acad Sci U S A (2008) 1.41
Integrated structural model and membrane targeting mechanism of the human ESCRT-II complex. Dev Cell (2008) 1.40
VHS domains of ESCRT-0 cooperate in high-avidity binding to polyubiquitinated cargo. EMBO J (2010) 1.40
Effects of denaturants on the dynamics of loop formation in polypeptides. Biophys J (2006) 1.39
Prediction of charge-induced molecular alignment of biomolecules dissolved in dilute liquid-crystalline phases. Biophys J (2004) 1.38
A HORMA domain in Atg13 mediates PI 3-kinase recruitment in autophagy. Proc Natl Acad Sci U S A (2013) 1.37
Two-site recognition of phosphatidylinositol 3-phosphate by PROPPINs in autophagy. Mol Cell (2012) 1.37
The Vps27/Hse1 complex is a GAT domain-based scaffold for ubiquitin-dependent sorting. Dev Cell (2007) 1.36