Published in J Biol Chem on November 25, 1975
Relative stability of alpha- and beta-globin messenger RNAs in homozygous beta+ thalassemia. Proc Natl Acad Sci U S A (1977) 1.36
In vitro transcription of chromatin in the presence of a mercurated nucleotide. Proc Natl Acad Sci U S A (1976) 1.25
RNA aggregation during sulfhydryl-agarose chromatography of mercurated RNA. Nucleic Acids Res (1977) 1.18
Limited accessibility of chromatin satellite DNA to RNA polymerase from Escherichia coli. Proc Natl Acad Sci U S A (1977) 1.01
Is there specific transcription from isolated chromatin? Nucleic Acids Res (1978) 0.92
Dephosphorylation of nonhistone proteins specifically alters the pattern of gene transcription in reconstituted chromatin. Proc Natl Acad Sci U S A (1976) 0.91
Characterization of chick liver chromatin and analysis of its in vitro transcription products. Nucleic Acids Res (1978) 0.85
The specificity of in vitro chromatin transcription. Nucleic Acids Res (1979) 0.80
In vitro DNA dependent synthesis of globin RNA sequences from erythroleukemic cell chromatin. Nucleic Acids Res (1979) 0.75
Effect of internal viral sequences on the utility of retroviral vectors. J Virol (1987) 6.06
Structure of the cro repressor from bacteriophage lambda and its interaction with DNA. Nature (1981) 5.24
Efficacy of deferoxamine in preventing complications of iron overload in patients with thalassemia major. N Engl J Med (1994) 4.86
Gene expression in mice after high efficiency retroviral-mediated gene transfer. Science (1985) 4.77
Localization of the human alpha-globin structural gene to chromosome 16 in somatic cell hybrids by molecular hybridization assay. Cell (1977) 4.34
Multiple sequence alignment. J Mol Biol (1986) 4.27
An oligomer complementary to c-myc mRNA inhibits proliferation of HL-60 promyelocytic cells and induces differentiation. Mol Cell Biol (1988) 4.08
Tandem AP-1-binding sites within the human beta-globin dominant control region function as an inducible enhancer in erythroid cells. Genes Dev (1990) 4.07
Prospects for human gene therapy. Science (1984) 3.93
A family of long reiterated DNA sequences, one copy of which is next to the human beta globin gene. Nucleic Acids Res (1980) 3.91
T lymphocyte-directed gene therapy for ADA- SCID: initial trial results after 4 years. Science (1995) 3.87
Inducible production of c-fos antisense RNA inhibits 3T3 cell proliferation. Proc Natl Acad Sci U S A (1986) 3.71
Self-inactivating retroviral vectors designed for transfer of whole genes into mammalian cells. Proc Natl Acad Sci U S A (1986) 3.68
DNA-binding proteins. Science (1983) 3.56
The molecular basis of DNA-protein recognition inferred from the structure of cro repressor. Nature (1982) 3.56
5-azacytidine selectively increases gamma-globin synthesis in a patient with beta+ thalassemia. N Engl J Med (1982) 3.29
The functional human dihydrofolate reductase gene. J Biol Chem (1984) 3.28
Structure and variation of human ribosomal DNA: molecular analysis of cloned fragments. Gene (1981) 3.18
RNA processing errors in patients with beta-thalassemia. Proc Natl Acad Sci U S A (1982) 2.99
Chromosomal organization of the human dihydrofolate reductase genes: dispersion, selective amplification, and a novel form of polymorphism. Proc Natl Acad Sci U S A (1984) 2.99
pH-independent murine leukemia virus ecotropic envelope-mediated cell fusion: implications for the role of the R peptide and p12E TM in viral entry. J Virol (1994) 2.87
Structural similarity in the DNA-binding domains of catabolite gene activator and cro repressor proteins. Proc Natl Acad Sci U S A (1982) 2.84
The regulation of initiation of mammalian protein synthesis. Prog Nucleic Acid Res Mol Biol (1981) 2.81
Differences in human alpha-, beta- and delta-globin gene expression in monkey kidney cells. Cell (1982) 2.78
A mouse model for beta-thalassemia. Cell (1983) 2.70
Established breast cancer risk factors by clinically important tumour characteristics. Br J Cancer (2006) 2.68
Isolation and partial characterization of reticulocyte factors M1 and M2. J Biol Chem (1970) 2.59
The properties of a nuclear acidic protein fraction that binds [6,7-3H]oestradiol-17beta. Biochem J (1969) 2.53
Regional gene assignment of human porphobilinogen deaminase and esterase A4 to chromosome 11q23 leads to 11qter. Proc Natl Acad Sci U S A (1981) 2.50
Augmentation by erythropoietin of the fetal-hemoglobin response to hydroxyurea in sickle cell disease. N Engl J Med (1993) 2.50
Human gene therapy. Annu Rev Biochem (1993) 2.49
Dysregulated interleukin 6 expression produces a syndrome resembling Castleman's disease in mice. J Clin Invest (1990) 2.37
Residues that mediate DNA binding of autoimmune antibodies. J Immunol (1993) 2.37
Continuous subcutaenous administration of deferoxamine in patients with iron overload. N Engl J Med (1977) 2.31
Molecular analysis of cloned human 18S ribosomal DNA segments. Proc Natl Acad Sci U S A (1978) 2.29
Expression of the human c-fms proto-oncogene in hematopoietic cells and its deletion in the 5q- syndrome. Cell (1985) 2.28
Factors for the initiation of haemoglobin synthesis by rabbit reticulocyte ribosomes. Nature (1970) 2.27
Detection of receptor-specific murine leukemia virus binding to cells by immunofluorescence analysis. J Virol (1992) 2.25
Cell-free hemoglobin synthesis. II. Characteristics of the transfer ribonucleic acid-dependent assay system. J Biol Chem (1970) 2.24
Covalent structure of a group-specific protease from rat small intestine. Appendix: crystallographic data for a group specific protease from rat intestine. Biochemistry (1978) 2.17
Beta O-39 thalassemia gene: a premature termination codon causes beta-mRNA deficiency without affecting cytoplasmic beta-mRNA stability. Blood (1984) 2.17
Developmental regulation of human globin genes. Annu Rev Biochem (1985) 2.16
Enforced expression of the GATA-2 transcription factor blocks normal hematopoiesis. Blood (1999) 2.14
Analysis of the functional and host range-determining regions of the murine ectropic and amphotropic retrovirus envelope proteins. J Virol (1993) 2.12
Identification of a subdomain in the Moloney murine leukemia virus envelope protein involved in receptor binding. J Virol (1996) 2.12
Replication and expression of thymidine kinase and human globin genes microinjected into mouse fibroblasts. Proc Natl Acad Sci U S A (1980) 2.10
Structure of the DNA-binding region of lac repressor inferred from its homology with cro repressor. Proc Natl Acad Sci U S A (1982) 2.09
Purification of the human NF-E2 complex: cDNA cloning of the hematopoietic cell-specific subunit and evidence for an associated partner. Mol Cell Biol (1993) 2.05
Cloning and characterization of DNA sequences surrounding the human gamma-, delta-, and beta-globin genes. Proc Natl Acad Sci U S A (1980) 2.04
Translation of exogenous messenger RNA for hemoglobin on reticulocyte and liver ribosomes. Proc Natl Acad Sci U S A (1971) 2.03
Inducibility of the HS II enhancer depends on binding of an erythroid specific nuclear protein. Nucleic Acids Res (1990) 2.01
Beta Thalassemia: mutations which affect processing of the beta-Globin mRNA precursor. Cell (1980) 1.98
Improved methods of retroviral vector transduction and production for gene therapy. Hum Gene Ther (1994) 1.95
Infection efficiency of T lymphocytes with amphotropic retroviral vectors is cell cycle dependent. J Virol (1989) 1.86
Kinetic studies on Cro repressor-operator DNA interaction. J Mol Biol (1987) 1.85
Pure red-cell aplasia of 10 years' duration due to persistent parvovirus B19 infection and its cure with immunoglobulin therapy. N Engl J Med (1989) 1.85
Combination of interleukins 3 and 6 preserves stem cell function in culture and enhances retrovirus-mediated gene transfer into hematopoietic stem cells. Proc Natl Acad Sci U S A (1989) 1.84
Purification and physical properties of homogeneous initiation factor MP from rabbit reticulocytes. J Biol Chem (1975) 1.83
Seeding of intravascular stents with genetically engineered endothelial cells. Circulation (1989) 1.82
Regulated high level expression of a human gamma-globin gene introduced into erythroid cells by an adeno-associated virus vector. Proc Natl Acad Sci U S A (1992) 1.82
Binding kinetics of ecotropic (Moloney) murine leukemia retrovirus with NIH 3T3 cells. J Virol (1995) 1.82
Many gene-regulatory proteins appear to have a similar alpha-helical fold that binds DNA and evolved from a common precursor. J Mol Evol (1983) 1.80
Expression of the human c-fms proto-oncogene product (colony-stimulating factor-1 receptor) on peripheral blood mononuclear cells and choriocarcinoma cell lines. J Clin Invest (1986) 1.77
Progesterone-binding components of chick oviduct. 3. Chromatin acceptor sites. J Biol Chem (1971) 1.77
Hepatic iron stores and plasma ferritin concentration in patients with sickle cell anemia and thalassemia major. Am J Hematol (1993) 1.76
Recombinant adeno-associated virus-mediated gene transfer into hematopoietic progenitor cells. Blood (1994) 1.75
Translation of rabbit haemoglobin messenger RNA by thalassaemic and non-thalassaemic ribosomes. Nat New Biol (1971) 1.75
Factors influencing in vivo transduction by recombinant adeno-associated viral vectors expressing the human factor IX cDNA. Blood (2001) 1.74
Isolation and translation of hemoglobin messenger RNA from thalassemia, sickle cell anemia, and normal human reticulocytes. J Clin Invest (1971) 1.74
Functional analysis of the cytoplasmic tail of Moloney murine leukemia virus envelope protein. J Virol (1997) 1.70
Intronless human dihydrofolate reductase genes are derived from processed RNA molecules. Proc Natl Acad Sci U S A (1982) 1.69
Uncoupled expression of Moloney murine leukemia virus envelope polypeptides SU and TM: a functional analysis of the role of TM domains in viral entry. J Virol (1994) 1.69
Inhibition of protein synthesis in rabbit reticulocyte lysates by double-stranded RNA and oxidized glutathione: indirect mode of action on polypeptide chain initiation. Proc Natl Acad Sci U S A (1975) 1.68
Mechanism of DNase I hypersensitive site formation within the human globin locus control region. Proc Natl Acad Sci U S A (1992) 1.67
Retroviral vectors containing putative internal ribosome entry sites: development of a polycistronic gene transfer system and applications to human gene therapy. Nucleic Acids Res (1992) 1.66
The interleukin 3 gene is located on human chromosome 5 and is deleted in myeloid leukemias with a deletion of 5q. Proc Natl Acad Sci U S A (1987) 1.64
Targeted and highly efficient gene transfer into CD4+ cells by a recombinant human immunodeficiency virus retroviral vector. J Clin Invest (1991) 1.64
Active conformation of the globin genes in uninduced and induced mouse erythroleukemia cells. Cell (1978) 1.64
Human gene therapy protocols: RAC review. Science (1995) 1.64
Nucleotide sequence of the dmsABC operon encoding the anaerobic dimethylsulphoxide reductase of Escherichia coli. Mol Microbiol (1988) 1.63
Hematologic responses of patients with sickle cell disease to treatment with hydroxyurea. N Engl J Med (1990) 1.63
Protamine sulfate as an effective alternative to polybrene in retroviral-mediated gene-transfer: implications for human gene therapy. J Virol Methods (1989) 1.63
Purification and characterization of heterogeneous pluripotent hematopoietic stem cell populations expressing high levels of c-kit receptor. Blood (1993) 1.62
Prospects for in utero human gene therapy. Science (1999) 1.61
5-Azacytidine increases gamma-globin synthesis and reduces the proportion of dense cells in patients with sickle cell anemia. Blood (1983) 1.61
Transduction and expression of the human carcinoembryonic antigen gene in a murine colon carcinoma cell line. Cancer Res (1991) 1.60
Further delineation of the dup(3q) syndrome. Am J Med Genet (1985) 1.60
Structural and functional homology of parvovirus and papovavirus polypeptides. J Gen Virol (1987) 1.59
Retracted Heparin-binding growth factor 1 induces the formation of organoid neovascular structures in vivo. Proc Natl Acad Sci U S A (1989) 1.59
Phenotypic delineation of ring chromosome 15 and Russell-Silver syndromes. J Med Genet (1985) 1.59
Development of a high-titer retrovirus producer cell line capable of gene transfer into rhesus monkey hematopoietic stem cells. Proc Natl Acad Sci U S A (1990) 1.59
Selective activation of human beta-but not gamma-globin gene in human fibroblast x mouse erythroleukaemia cell hybrids. Nature (1979) 1.58