Published in EMBO J on March 01, 2002
The TetR family of transcriptional repressors. Microbiol Mol Biol Rev (2005) 6.02
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Molecular mechanism by which the nucleoid occlusion factor, SlmA, keeps cytokinesis in check. EMBO J (2010) 1.72
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Structural mechanism of the simultaneous binding of two drugs to a multidrug-binding protein. EMBO J (2004) 1.47
Antibiotic-dependent induction of Pseudomonas putida DOT-T1E TtgABC efflux pump is mediated by the drug binding repressor TtgR. Antimicrob Agents Chemother (2003) 1.34
Crystal structure of the Vibrio cholerae quorum-sensing regulatory protein HapR. J Bacteriol (2007) 1.32
In vivo and in vitro evidence that TtgV is the specific regulator of the TtgGHI multidrug and solvent efflux pump of Pseudomonas putida. J Bacteriol (2003) 1.31
Crystal structure of the transcriptional regulator CmeR from Campylobacter jejuni. J Mol Biol (2007) 1.28
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Crystal structure of the transcriptional regulator AcrR from Escherichia coli. J Mol Biol (2007) 1.21
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Characterization of the multiple transferable resistance repressor, MtrR, from Neisseria gonorrhoeae. J Bacteriol (2005) 1.18
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The TetR family of regulators. Microbiol Mol Biol Rev (2013) 1.14
The binding of triclosan to SmeT, the repressor of the multidrug efflux pump SmeDEF, induces antibiotic resistance in Stenotrophomonas maltophilia. PLoS Pathog (2011) 1.12
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Characterization of the multidrug efflux regulator AcrR from Escherichia coli. Biochem Biophys Res Commun (2007) 1.05
Structural and functional analysis of SmeT, the repressor of the Stenotrophomonas maltophilia multidrug efflux pump SmeDEF. J Biol Chem (2009) 1.03
The purine repressor of Bacillus subtilis: a novel combination of domains adapted for transcription regulation. J Bacteriol (2003) 1.03
Toxin-antitoxin regulation: bimodal interaction of YefM-YoeB with paired DNA palindromes exerts transcriptional autorepression. Nucleic Acids Res (2006) 1.03
The crystal structure of the TetR family transcriptional repressor SimR bound to DNA and the role of a flexible N-terminal extension in minor groove binding. Nucleic Acids Res (2011) 1.02
The pqrAB operon is responsible for paraquat resistance in Streptomyces coelicolor. J Bacteriol (2003) 1.00
Structural and functional analysis of the transcriptional regulator Rv3066 of Mycobacterium tuberculosis. Nucleic Acids Res (2012) 1.00
The IclR family of transcriptional activators and repressors can be defined by a single profile. Protein Sci (2006) 0.99
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Binding of the RamR repressor to wild-type and mutated promoters of the RamA gene involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium. Antimicrob Agents Chemother (2011) 0.97
Crystal structure of SmcR, a quorum-sensing master regulator of Vibrio vulnificus, provides insight into its regulation of transcription. J Biol Chem (2010) 0.96
Crystal structure of IcaR, a repressor of the TetR family implicated in biofilm formation in Staphylococcus epidermidis. Nucleic Acids Res (2008) 0.96
Multidrug efflux pumps from Enterobacteriaceae, Vibrio cholerae and Staphylococcus aureus bacterial food pathogens. Int J Environ Res Public Health (2015) 0.96
QacR-cation recognition is mediated by a redundancy of residues capable of charge neutralization. Biochemistry (2008) 0.95
Multidrug Efflux Pumps in Staphylococcus aureus: an Update. Open Microbiol J (2013) 0.95
Structural basis for LEAFY floral switch function and similarity with helix-turn-helix proteins. EMBO J (2008) 0.95
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The fusidic acid stimulon of Staphylococcus aureus. J Antimicrob Chemother (2008) 0.88
Structural and mechanistic basis of zinc regulation across the E. coli Zur regulon. PLoS Biol (2014) 0.88
Structural basis for antibiotic recognition by the TipA class of multidrug-resistance transcriptional regulators. EMBO J (2003) 0.88
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Structural basis of cooperative DNA recognition by the plasmid conjugation factor, TraM. Nucleic Acids Res (2011) 0.87
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Structural mechanism of signal transduction between the RNA-binding domain and the phosphotransferase system regulation domain of the LicT antiterminator. J Biol Chem (2008) 0.86
Structural and functional basis of transcriptional regulation by TetR family protein CprB from S. coelicolor A3(2). Nucleic Acids Res (2014) 0.86
Structural plasticity and distinct drug-binding modes of LfrR, a mycobacterial efflux pump regulator. J Bacteriol (2009) 0.85
Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of the regulator AcrR from Escherichia coli. Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 0.85
The protein-DNA contacts in RutR•carAB operator complexes. Nucleic Acids Res (2010) 0.85
Crystal structure of a transcriptional regulator TM1030 from Thermotoga maritima solved by an unusual MAD experiment. J Struct Biol (2007) 0.84
Recognition of dual symmetry by the controller protein C.Esp1396I based on the structure of the transcriptional activation complex. Nucleic Acids Res (2011) 0.84
Re-visiting protein-centric two-tier classification of existing DNA-protein complexes. BMC Bioinformatics (2012) 0.84
Structural activation of the transcriptional repressor EthR from Mycobacterium tuberculosis by single amino acid change mimicking natural and synthetic ligands. Nucleic Acids Res (2011) 0.83
Transcriptional repression mediated by a TetR family protein, PfmR, from Thermus thermophilus HB8. J Bacteriol (2012) 0.82
Crystal structure of Bacillus cereus HlyIIR, a transcriptional regulator of the gene for pore-forming toxin hemolysin II. J Mol Biol (2006) 0.82
Preliminary structural studies of the transcriptional regulator CmeR from Campylobacter jejuni. Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 0.81
Conformational change of the AcrR regulator reveals a possible mechanism of induction. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 0.81
Functional consequences of substitution mutations in MepR, a repressor of the Staphylococcus aureus MepA multidrug efflux pump gene. J Bacteriol (2013) 0.80
Regulation of RamA by RamR in Salmonella enterica serovar Typhimurium: isolation of a RamR superrepressor. Antimicrob Agents Chemother (2012) 0.79
Crystal and solution studies reveal that the transcriptional regulator AcnR of Corynebacterium glutamicum is regulated by citrate-Mg2+ binding to a non-canonical pocket. J Biol Chem (2013) 0.79
Structural basis for interaction between Mycobacterium smegmatis Ms6564, a TetR family master regulator, and its target DNA. J Biol Chem (2013) 0.79
Structural analysis of DNA-protein complexes regulating the restriction-modification system Esp1396I. Acta Crystallogr Sect F Struct Biol Cryst Commun (2013) 0.79
Structural Basis for the Regulation of the MmpL Transporters of Mycobacterium tuberculosis. J Biol Chem (2015) 0.79
A single acidic residue can guide binding site selection but does not govern QacR cationic-drug affinity. PLoS One (2011) 0.79
Thermodynamics of cooperative DNA recognition at a replication origin and transcription regulatory site. Biochemistry (2010) 0.79
Structural and functional characterization of a ketosteroid transcriptional regulator of Mycobacterium tuberculosis. J Biol Chem (2014) 0.79
Genome-scale analysis reveals a role for NdgR in the thiol oxidative stress response in Streptomyces coelicolor. BMC Genomics (2015) 0.79
Mutations within the mepA operator affect binding of the MepR regulatory protein and its induction by MepA substrates in Staphylococcus aureus. J Bacteriol (2015) 0.77
Physical basis of the inducer-dependent cooperativity of the Central glycolytic genes Repressor/DNA complex. Nucleic Acids Res (2010) 0.77
Using synthetic bacterial enhancers to reveal a looping-based mechanism for quenching-like repression. Nat Commun (2016) 0.77
Ligand binding specificity of RutR, a member of the TetR family of transcription regulators in Escherichia coli. FEBS Open Bio (2015) 0.76
Crystal structure of the Mycobacterium tuberculosis transcriptional regulator Rv0302. Protein Sci (2015) 0.76
The AibR-isovaleryl coenzyme A regulator and its DNA binding site - a model for the regulation of alternative de novo isovaleryl coenzyme A biosynthesis in Myxococcus xanthus. Nucleic Acids Res (2016) 0.75
The TetR-type transcriptional repressor RolR from Corynebacterium glutamicum regulates resorcinol catabolism by binding to a unique operator, rolO. Appl Environ Microbiol (2012) 0.75
Structural basis of operator sites recognition and effector binding in the TetR family transcription regulator FadR. Nucleic Acids Res (2017) 0.75
Mutation in the sdeS gene promotes expression of the sdeAB efflux pump genes and multidrug resistance in Serratia marcescens. Antimicrob Agents Chemother (2011) 0.75
Crystallization and preliminary X-ray diffraction analysis of the TetR-family transcriptional repressor YhgD from Bacillus halodurans. Acta Crystallogr Sect F Struct Biol Cryst Commun (2013) 0.75
Pfit is a structurally novel Crohn's disease-associated superantigen. PLoS Pathog (2013) 0.75
Transcription factor-based biosensors enlightened by the analyte. Front Microbiol (2015) 0.75
Crystal Structure of Fad35R from Mycobacterium tuberculosis H37Rv in the Apo-State. PLoS One (2015) 0.75
Quorum sensing gene regulation by LuxR/HapR master regulators in vibrios. J Bacteriol (2017) 0.75
The length of glycine-rich linker in DNA-binding domain is critical for optimal functioning of quorum-sensing master regulatory protein HapR. Mol Genet Genomics (2014) 0.75
Crystal structure of the TetR family repressor, AlkX, from Dietzia sp. DQ12-45-1b implicated in biodegradation of n-alkanes. Appl Environ Microbiol (2017) 0.75
The zinc efflux activator SczA protects Streptococcus pneumoniae serotype 2 D39 from intracellular zinc toxicity. Mol Microbiol (2017) 0.75
Structural analysis of the regulatory mechanism of MarR protein Rv2887 in M. tuberculosis. Sci Rep (2017) 0.75
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