Published in J Cell Sci on March 15, 2002
Phagosome maturation: aging gracefully. Biochem J (2002) 3.42
An overview of the molecular mechanism of autophagy. Curr Top Microbiol Immunol (2009) 3.29
Activation and assembly of the NADPH oxidase: a structural perspective. Biochem J (2005) 3.02
Svp1p defines a family of phosphatidylinositol 3,5-bisphosphate effectors. EMBO J (2004) 2.73
The uniformity of phagosome maturation in macrophages. J Cell Biol (2004) 2.13
Inositol phospholipid metabolism in Arabidopsis. Characterized and putative isoforms of inositol phospholipid kinase and phosphoinositide-specific phospholipase C. Plant Physiol (2002) 2.07
Subcellular localization and function of alternatively spliced Noxo1 isoforms. Free Radic Biol Med (2006) 1.76
Pleckstrin homology (PH) domains and phosphoinositides. Biochem Soc Symp (2007) 1.74
Fab1 phosphatidylinositol 3-phosphate 5-kinase controls trafficking but not silencing of endocytosed receptors. Mol Biol Cell (2006) 1.68
Determining selectivity of phosphoinositide-binding domains. Methods (2006) 1.62
FAM65B is a membrane-associated protein of hair cell stereocilia required for hearing. Proc Natl Acad Sci U S A (2014) 1.57
Akt/protein kinase B-dependent phosphorylation and inactivation of WEE1Hu promote cell cycle progression at G2/M transition. Mol Cell Biol (2005) 1.56
Phosphatidylinositol 3-phosphate is found in microdomains of early endosomes. Histochem Cell Biol (2003) 1.27
Atg6 is required for multiple vesicle trafficking pathways and hematopoiesis in Drosophila. Development (2013) 1.20
Mutations in the Arabidopsis phosphoinositide phosphatase gene SAC9 lead to overaccumulation of PtdIns(4,5)P2 and constitutive expression of the stress-response pathway. Plant Physiol (2005) 1.11
The Autophagy Database: an all-inclusive information resource on autophagy that provides nourishment for research. Nucleic Acids Res (2010) 1.05
Phosphatidylinositol 3-phosphate indirectly activates KCa3.1 via 14 amino acids in the carboxy terminus of KCa3.1. Mol Biol Cell (2005) 1.03
Three sorting nexins drive the degradation of apoptotic cells in response to PtdIns(3)P signaling. Mol Biol Cell (2011) 1.02
Phosphatidylinositol 3-monophosphate is involved in toxoplasma apicoplast biogenesis. PLoS Pathog (2011) 0.99
AKT-independent PI3-K signaling in cancer - emerging role for SGK3. Cancer Manag Res (2013) 0.99
MoVam7, a conserved SNARE involved in vacuole assembly, is required for growth, endocytosis, ROS accumulation, and pathogenesis of Magnaporthe oryzae. PLoS One (2011) 0.95
Frank-ter Haar syndrome protein Tks4 regulates epidermal growth factor-dependent cell migration. J Biol Chem (2012) 0.93
TCGAP, a multidomain Rho GTPase-activating protein involved in insulin-stimulated glucose transport. EMBO J (2003) 0.93
p47phox Phox homology domain regulates plasma membrane but not phagosome neutrophil NADPH oxidase activation. J Biol Chem (2010) 0.90
Overexpression of the autoantigen IA-2 puts beta cells into a pre-apoptotic state: autoantigen-induced, but non-autoimmune-mediated, tissue destruction. Clin Exp Immunol (2007) 0.86
Gelsolin binds to polyphosphoinositide-free lipid vesicles and simultaneously to actin microfilaments. Biochem J (2005) 0.85
SLIC-1/sorting nexin 20: a novel sorting nexin that directs subcellular distribution of PSGL-1. Eur J Immunol (2008) 0.84
Solution structure of human sorting nexin 22. Protein Sci (2007) 0.83
Characterization of PXK as a protein involved in epidermal growth factor receptor trafficking. Mol Cell Biol (2010) 0.83
Membrane protein location-dependent regulation by PI3K (III) and rabenosyn-5 in Drosophila wing cells. PLoS One (2009) 0.83
PX-FERM proteins: A link between endosomal trafficking and signaling? Small GTPases (2011) 0.83
In silico analysis of HLA associations with drug-induced liver injury: use of a HLA-genotyped DNA archive from healthy volunteers. Genome Med (2012) 0.81
Inhibitors of phosphoinositide 3-kinase cause defects in the postendocytic sorting of beta2-adrenergic receptors. Exp Cell Res (2007) 0.78
Receptor-mediated Endocytosis 8 Utilizes an N-terminal Phosphoinositide-binding Motif to Regulate Endosomal Clathrin Dynamics. J Biol Chem (2015) 0.76
The GTP- and Phospholipid-Binding Protein TTD14 Regulates Trafficking of the TRPL Ion Channel in Drosophila Photoreceptor Cells. PLoS Genet (2015) 0.76
ENDOSOMAL RAB EFFECTOR WITH PX-DOMAIN, an Interacting Partner of RAB5 GTPases, Regulates Membrane Trafficking to Protein Storage Vacuoles in Arabidopsis. Plant Cell (2016) 0.75
The role and regulation of Rab40b-Tks5 complex during invadopodia formation and cancer cell invasion. J Cell Sci (2016) 0.75
Tir Is Essential for the Recruitment of Tks5 to Enteropathogenic Escherichia coli Pedestals. PLoS One (2015) 0.75
Crystal structure of designed PX domain from cytokine-independent survival kinase and implications on evolution-based protein engineering. J Struct Biol (2015) 0.75
Expression of sorting nexin 18 (SNX18) is dynamically regulated in developing spinal motor neurons. J Histochem Cytochem (2011) 0.75
Effect of phosphatidylcholine on pld gene expression level of Aspergillus fumigatus by the real time PCR method and investigations of these genes using bioinformatics analysis. Iran J Microbiol (2012) 0.75
SGK3 (CISK) may induce tumor angiogenesis (Hypothesis). Oncol Lett (2015) 0.75
Innovative techniques and applications in histochemistry and cell biology. Histochem Cell Biol (2003) 0.75
SNX10 promotes phagosome maturation in macrophages and protects mice against Listeria monocytogenes infection. Oncotarget (2017) 0.75
Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation. Nature (2011) 9.33
Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency. Nature (2010) 8.84
Preferential associations between co-regulated genes reveal a transcriptional interactome in erythroid cells. Nat Genet (2009) 6.39
The dynamics of genome-wide DNA methylation reprogramming in mouse primordial germ cells. Mol Cell (2012) 4.32
Global mapping of DNA methylation in mouse promoters reveals epigenetic reprogramming of pluripotency genes. PLoS Genet (2008) 3.89
P-Rex1, a PtdIns(3,4,5)P3- and Gbetagamma-regulated guanine-nucleotide exchange factor for Rac. Cell (2002) 3.80
PI(3)Kgamma has an important context-dependent role in neutrophil chemokinesis. Nat Cell Biol (2006) 3.12
FGF signaling inhibition in ESCs drives rapid genome-wide demethylation to the epigenetic ground state of pluripotency. Cell Stem Cell (2013) 2.79
Quantification of PtdInsP3 molecular species in cells and tissues by mass spectrometry. Nat Methods (2011) 2.56
Structure of lipid kinase p110β/p85β elucidates an unusual SH2-domain-mediated inhibitory mechanism. Mol Cell (2011) 2.50
Sequential activation of class IB and class IA PI3K is important for the primed respiratory burst of human but not murine neutrophils. Blood (2005) 2.35
Dynamic stage-specific changes in imprinted differentially methylated regions during early mammalian development and prevalence of non-CpG methylation in oocytes. Development (2011) 2.28
Phosphoinositide 3-kinase-dependent activation of Rac. FEBS Lett (2003) 2.11
Neutrophils from p40phox-/- mice exhibit severe defects in NADPH oxidase regulation and oxidant-dependent bacterial killing. J Exp Med (2006) 2.01
P-Rex1 regulates neutrophil function. Curr Biol (2005) 1.97
PI3Kβ plays a critical role in neutrophil activation by immune complexes. Sci Signal (2011) 1.95
A screen for hydroxymethylcytosine and formylcytosine binding proteins suggests functions in transcription and chromatin regulation. Genome Biol (2013) 1.50
Deletion of the RNA-binding proteins ZFP36L1 and ZFP36L2 leads to perturbed thymic development and T lymphoblastic leukemia. Nat Immunol (2010) 1.49
Regulation of P-Rex1 by phosphatidylinositol (3,4,5)-trisphosphate and Gbetagamma subunits. J Biol Chem (2004) 1.49
An unbiased assessment of the role of imprinted genes in an intergenerational model of developmental programming. PLoS Genet (2012) 1.34
P-Rex2, a new guanine-nucleotide exchange factor for Rac. FEBS Lett (2004) 1.33
PtdIns3P binding to the PX domain of p40phox is a physiological signal in NADPH oxidase activation. EMBO J (2006) 1.22
PI3K class IB pathway in neutrophils. Sci STKE (2007) 1.11
PI3Kgamma is a key regulator of inflammatory responses and cardiovascular homeostasis. Science (2007) 1.10
ARAP3 is essential for formation of lamellipodia after growth factor stimulation. J Cell Sci (2006) 1.09
Regulation of PTEN inhibition by the pleckstrin homology domain of P-REX2 during insulin signaling and glucose homeostasis. Proc Natl Acad Sci U S A (2013) 1.07
Two distinct functions for PI3-kinases in macropinocytosis. J Cell Sci (2013) 1.03
Regulation of phosphatidylinositol 3-kinase activity and phosphatidylinositol 3,4,5-trisphosphate accumulation by neutrophil priming agents. J Immunol (2002) 1.03
PI3K signaling in neutrophils. Curr Top Microbiol Immunol (2010) 1.02
Age-dependent axonal transport and locomotor changes and tau hypophosphorylation in a "P301L" tau knockin mouse. Neurobiol Aging (2011) 0.99
Class IA phosphoinositide 3-kinase β and δ regulate neutrophil oxidase activation in response to Aspergillus fumigatus hyphae. J Immunol (2011) 0.98
Quantitative measurement of phosphatidylinositol 3,4,5-trisphosphate. Methods Enzymol (2007) 0.96
DNA methylation profiles define stem cell identity and reveal a tight embryonic-extraembryonic lineage boundary. Stem Cells (2012) 0.96
Lysophosphatidylinositol-acyltransferase-1 (LPIAT1) is required to maintain physiological levels of PtdIns and PtdInsP(2) in the mouse. PLoS One (2013) 0.95
Mechanism of the regulation of type IB phosphoinositide 3OH-kinase byG-protein betagamma subunits. Biochem J (2002) 0.93
PI3K signaling through the dual GTPase-activating protein ARAP3 is essential for developmental angiogenesis. Sci Signal (2010) 0.92
PtdIns3P and Rac direct the assembly of the NADPH oxidase on a novel, pre-phagosomal compartment during FcR-mediated phagocytosis in primary mouse neutrophils. Blood (2010) 0.91
Use of the GRP1 PH domain as a tool to measure the relative levels of PtdIns(3,4,5)P3 through a protein-lipid overlay approach. J Lipid Res (2006) 0.91
Role of rpoS in the development of cell envelope resilience and pressure resistance in stationary-phase Escherichia coli. Appl Environ Microbiol (2011) 0.89
The role of PI3Ks in the regulation of the neutrophil NADPH oxidase. Biochem Soc Symp (2007) 0.89
RhoG regulates the neutrophil NADPH oxidase. J Immunol (2006) 0.89
Hypomethylation of functional retrotransposon-derived genes in the human placenta. Mamm Genome (2011) 0.87
PI3K class IB pathway. Sci STKE (2007) 0.86
Structural determinants of LL5beta subcellular localisation and association with filamin C. Cell Signal (2006) 0.86
Phosphorylation of threonine 154 in p40phox is an important physiological signal for activation of the neutrophil NADPH oxidase. Blood (2010) 0.86
High-throughput analysis of calcium signalling kinetics in astrocytes stimulated with different neurotransmitters. PLoS One (2011) 0.85
Deficiency in spliceosome-associated factor CTNNBL1 does not affect ongoing cell cycling but delays exit from quiescence and results in embryonic lethality in mice. Cell Cycle (2013) 0.82
Activation of the neutrophil NADPH oxidase by Aspergillus fumigatus. Ann N Y Acad Sci (2012) 0.82
What is the advantage of a transient precursor in autophagosome biogenesis? Autophagy (2011) 0.80
The hexosamine biosynthesis pathway and O-GlcNAcylation maintain insulin-stimulated PI3K-PKB phosphorylation and tumour cell growth after short-term glucose deprivation. FEBS J (2014) 0.80
Signaling via class IA Phosphoinositide 3-kinases (PI3K) in human, breast-derived cell lines. PLoS One (2013) 0.78
TRP channels at a glance. J Cell Sci (2004) 0.78
3D time series analysis of cell shape using Laplacian approaches. BMC Bioinformatics (2013) 0.76