Published in Nat Methods on January 30, 2011
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PI4P and PI(4,5)P2 are essential but independent lipid determinants of membrane identity. Science (2012) 3.05
Mosaic overgrowth with fibroadipose hyperplasia is caused by somatic activating mutations in PIK3CA. Nat Genet (2012) 1.74
Ionic immune suppression within the tumour microenvironment limits T cell effector function. Nature (2016) 1.63
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Separation of fluorescently labeled phosphoinositides and sphingolipids by capillary electrophoresis. J Chromatogr B Analyt Technol Biomed Life Sci (2012) 0.77
Insulin resistance uncoupled from dyslipidemia due to C-terminal PIK3R1 mutations. JCI Insight (2016) 0.76
Requirement of Phosphoinositides Containing Stearic Acid To Control Cell Polarity. Mol Cell Biol (2015) 0.76
Phosphatidylinositolphosphate phosphatase activities and cancer. J Lipid Res (2015) 0.76
Oxysterol-binding Protein Activation at Endoplasmic Reticulum-Golgi Contact Sites Reorganizes Phosphatidylinositol 4-Phosphate Pools. J Biol Chem (2015) 0.76
Fatty-acyl chain profiles of cellular phosphoinositides. Biochim Biophys Acta (2017) 0.75
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Neutral not a loss: phosphoinositides beyond the head group. Nat Methods (2011) 0.75
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The acyltransferase LYCAT controls specific phosphoinositides and related membrane traffic. Mol Biol Cell (2016) 0.75
In B cells, phosphatidylinositol 5-phosphate 4-kinase-α synthesizes PI(4,5)P2 to impact mTORC2 and Akt signaling. Proc Natl Acad Sci U S A (2016) 0.75
Coincident signals from GPCRs and receptor tyrosine kinases are uniquely transduced by PI3Kβ in myeloid cells. Sci Signal (2016) 0.75
Investigating the effect of arachidonate supplementation on the phosphoinositide content of MCF10a breast epithelial cells. Adv Biol Regul (2015) 0.75
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Pathway of phosphatidylinositol(3,4,5)-trisphosphate synthesis in activated neutrophils. Nature (1991) 3.41
Sequential activation of class IB and class IA PI3K is important for the primed respiratory burst of human but not murine neutrophils. Blood (2005) 2.35
To stabilize neutrophil polarity, PIP3 and Cdc42 augment RhoA activity at the back as well as signals at the front. J Cell Biol (2006) 2.10
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The alternative stimulatory G protein alpha-subunit XLalphas is a critical regulator of energy and glucose metabolism and sympathetic nerve activity in adult mice. J Biol Chem (2006) 1.27
A targeted mass spectrometric analysis of phosphatidylinositol phosphate species. J Lipid Res (2005) 1.22
Analyzing phosphoinositides and their interacting proteins. Nat Methods (2006) 1.21
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Regulation of phosphatidylinositol 3-kinase activity and phosphatidylinositol 3,4,5-trisphosphate accumulation by neutrophil priming agents. J Immunol (2002) 1.03
Isolation, structural elucidation, and absolute stereochemistry of enigmazole A, a cytotoxic phosphomacrolide from the Papua New Guinea marine sponge Cinachyrella enigmatica. J Am Chem Soc (2010) 0.97
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Reversed-phase LC/MS method for polyphosphoinositide analyses: changes in molecular species levels during epidermal growth factor activation in A431 cells. Anal Chem (2008) 0.91
Use of the GRP1 PH domain as a tool to measure the relative levels of PtdIns(3,4,5)P3 through a protein-lipid overlay approach. J Lipid Res (2006) 0.91
The identification of a novel inositol lipid, phosphatidylinositol trisphosphate (PIP3), in rat cerebrum using in vivo techniques. Biochem Biophys Res Commun (1989) 0.90
Phosphoinositide and inositol phosphate analysis in lymphocyte activation. Curr Protoc Immunol (2009) 0.85
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science (2007) 37.88
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Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet (2010) 7.94
Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet (2009) 5.81
Update of the LIPID MAPS comprehensive classification system for lipids. J Lipid Res (2008) 4.01
PI 3-kinase p110beta: a new target for antithrombotic therapy. Nat Med (2005) 3.96
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Common variation in the FTO gene alters diabetes-related metabolic traits to the extent expected given its effect on BMI. Diabetes (2008) 3.76
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Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet (2012) 3.21
PI4P and PI(4,5)P2 are essential but independent lipid determinants of membrane identity. Science (2012) 3.05
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P-Rex1 regulates neutrophil function. Curr Biol (2005) 1.97
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Gbetagammas and the Ras binding domain of p110gamma are both important regulators of PI(3)Kgamma signalling in neutrophils. Nat Cell Biol (2006) 1.76
Downregulation of adipose tissue fatty acid trafficking in obesity: a driver for ectopic fat deposition? Diabetes (2010) 1.76
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DNA damage-induced Bcl-xL deamidation is mediated by NHE-1 antiport regulated intracellular pH. PLoS Biol (2007) 1.66
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