Published in J Mol Biol on March 15, 2002
How phosphotransferase system-related protein phosphorylation regulates carbohydrate metabolism in bacteria. Microbiol Mol Biol Rev (2006) 6.39
CcpA-dependent carbon catabolite repression in bacteria. Microbiol Mol Biol Rev (2003) 2.21
Structural and functional characterization of nonstructural protein 2 for its role in hepatitis C virus assembly. J Biol Chem (2008) 1.71
Identification of a novel determinant for membrane association in hepatitis C virus nonstructural protein 4B. J Virol (2009) 1.37
The C terminus of hepatitis C virus NS4A encodes an electrostatic switch that regulates NS5A hyperphosphorylation and viral replication. J Virol (2007) 1.32
NMR structure and ion channel activity of the p7 protein from hepatitis C virus. J Biol Chem (2010) 1.21
Solid state NMR sequential resonance assignments and conformational analysis of the 2x10.4 kDa dimeric form of the Bacillus subtilis protein Crh. J Biomol NMR (2003) 1.21
Identification of new functional regions in hepatitis C virus envelope glycoprotein E2. J Virol (2010) 1.15
Antiviral activity of α-helical stapled peptides designed from the HIV-1 capsid dimerization domain. Retrovirology (2011) 0.99
Structural constraints for the Crh protein from solid-state NMR experiments. J Biomol NMR (2008) 0.84
Effect of adaptation to ethanol on cytoplasmic and membrane protein profiles of Oenococcus oeni. Appl Environ Microbiol (2004) 0.83
Structural analysis of hepatitis C virus core-E1 signal peptide and requirements for cleavage of the genotype 3a signal sequence by signal peptide peptidase. J Virol (2012) 0.81
Triosephosphate isomerase: 15N and 13C chemical shift assignments and conformational change upon ligand binding by magic-angle spinning solid-state NMR spectroscopy. J Mol Biol (2009) 0.80
Backbone dynamics of a biologically active human FGF-1 monomer, complexed to a hexasaccharide heparin-analogue, by 15N NMR relaxation methods. J Biomol NMR (2006) 0.80
NS2 proteins of GB virus B and hepatitis C virus share common protease activities and membrane topologies. J Virol (2014) 0.78
The histidine-phosphocarrier protein of the phosphoenolpyruvate: sugar phosphotransferase system of Bacillus sphaericus self-associates. PLoS One (2013) 0.78
Simultaneous use of solution, solid-state NMR and X-ray crystallography to study the conformational landscape of the Crh protein during oligomerization and crystallization. Adv Appl Bioinform Chem (2010) 0.75
Consensus proposals for a unified system of nomenclature of hepatitis C virus genotypes. Hepatology (2005) 9.39
Replication of hepatitis C virus. Nat Rev Microbiol (2007) 8.31
Structural characterization of flexible proteins using small-angle X-ray scattering. J Am Chem Soc (2007) 6.53
An amino-terminal amphipathic alpha-helix mediates membrane association of the hepatitis C virus nonstructural protein 5A. J Biol Chem (2001) 3.91
Very fast two-dimensional NMR spectroscopy for real-time investigation of dynamic events in proteins on the time scale of seconds. J Am Chem Soc (2005) 2.81
SOFAST-HMQC experiments for recording two-dimensional heteronuclear correlation spectra of proteins within a few seconds. J Biomol NMR (2005) 2.53
euHCVdb: the European hepatitis C virus database. Nucleic Acids Res (2006) 2.41
Identification of slow correlated motions in proteins using residual dipolar and hydrogen-bond scalar couplings. Proc Natl Acad Sci U S A (2005) 2.35
A structural model for unfolded proteins from residual dipolar couplings and small-angle x-ray scattering. Proc Natl Acad Sci U S A (2005) 2.28
Structure of tumor suppressor p53 and its intrinsically disordered N-terminal transactivation domain. Proc Natl Acad Sci U S A (2008) 2.14
Exploring multiple timescale motions in protein GB3 using accelerated molecular dynamics and NMR spectroscopy. J Am Chem Soc (2007) 2.04
Complete genome sequence of the probiotic Lactobacillus casei strain BL23. J Bacteriol (2010) 1.98
Discovering lactic acid bacteria by genomics. Antonie Van Leeuwenhoek (2002) 1.90
Subcellular localization and topology of the p7 polypeptide of hepatitis C virus. J Virol (2002) 1.89
MAVS dimer is a crucial signaling component of innate immunity and the target of hepatitis C virus NS3/4A protease. J Virol (2008) 1.86
Membrane association of hepatitis C virus nonstructural proteins and identification of the membrane alteration that harbors the viral replication complex. Antiviral Res (2003) 1.76
Defining long-range order and local disorder in native alpha-synuclein using residual dipolar couplings. J Am Chem Soc (2005) 1.75
Interaction of hepatitis C virus proteins with host cell membranes and lipids. Trends Cell Biol (2002) 1.71
The neutralizing activity of anti-hepatitis C virus antibodies is modulated by specific glycans on the E2 envelope protein. J Virol (2007) 1.69
Tyrosine phosphorylation: an emerging regulatory device of bacterial physiology. Trends Biochem Sci (2007) 1.69
Speeding up three-dimensional protein NMR experiments to a few minutes. J Am Chem Soc (2006) 1.65
Structural determinants for membrane association and dynamic organization of the hepatitis C virus NS3-4A complex. Proc Natl Acad Sci U S A (2008) 1.62
Hepatitis C virus NS5A protein is a substrate for the peptidyl-prolyl cis/trans isomerase activity of cyclophilins A and B. J Biol Chem (2009) 1.61
A set of BEST triple-resonance experiments for time-optimized protein resonance assignment. J Magn Reson (2007) 1.60
Characterization of fusion determinants points to the involvement of three discrete regions of both E1 and E2 glycoproteins in the membrane fusion process of hepatitis C virus. J Virol (2007) 1.59
Evidence of viral replication in circulating dendritic cells during hepatitis C virus infection. J Infect Dis (2003) 1.59
The YvcK protein is required for morphogenesis via localization of PBP1 under gluconeogenic growth conditions in Bacillus subtilis. Mol Microbiol (2011) 1.57
The hepatitis C virus RNA-dependent RNA polymerase membrane insertion sequence is a transmembrane segment. J Virol (2002) 1.56
Toward a unified representation of protein structural dynamics in solution. J Am Chem Soc (2009) 1.55
Transmembrane modulator-dependent bacterial tyrosine kinase activates UDP-glucose dehydrogenases. EMBO J (2003) 1.55
A functional genomics approach to establish the complement of carbohydrate transporters in Streptococcus pneumoniae. PLoS One (2012) 1.53
NS2 protein of hepatitis C virus interacts with structural and non-structural proteins towards virus assembly. PLoS Pathog (2011) 1.52
Topological changes in the transmembrane domains of hepatitis C virus envelope glycoproteins. EMBO J (2002) 1.52
Elaborate transcription regulation of the Bacillus subtilis ilv-leu operon involved in the biosynthesis of branched-chain amino acids through global regulators of CcpA, CodY and TnrA. Mol Microbiol (2005) 1.49
Regulation of hepatitis C virus polyprotein processing by signal peptidase involves structural determinants at the p7 sequence junctions. J Biol Chem (2004) 1.49
Highly populated turn conformations in natively unfolded tau protein identified from residual dipolar couplings and molecular simulation. J Am Chem Soc (2007) 1.49
Hepatitis C virus proteins: from structure to function. Curr Top Microbiol Immunol (2013) 1.47
Solution structure of the E.coli TolA C-terminal domain reveals conformational changes upon binding to the phage g3p N-terminal domain. J Mol Biol (2005) 1.46
A thermodynamic switch modulates abscisic acid receptor sensitivity. EMBO J (2011) 1.44
NMR characterization of long-range order in intrinsically disordered proteins. J Am Chem Soc (2010) 1.43
Hepatitis C virus glycoproteins mediate low pH-dependent membrane fusion with liposomes. J Biol Chem (2005) 1.41
Frequent compartmentalization of hepatitis C virus variants in circulating B cells and monocytes. Hepatology (2004) 1.41
Structural basis for the regulation mechanism of the tyrosine kinase CapB from Staphylococcus aureus. PLoS Biol (2008) 1.38
Protein conformational flexibility from structure-free analysis of NMR dipolar couplings: quantitative and absolute determination of backbone motion in ubiquitin. Angew Chem Int Ed Engl (2009) 1.38
Horizontal gene transfer in the molecular evolution of mannose PTS transporters. Mol Biol Evol (2005) 1.37
Identification of a novel determinant for membrane association in hepatitis C virus nonstructural protein 4B. J Virol (2009) 1.37
Membrane association of the RNA-dependent RNA polymerase is essential for hepatitis C virus RNA replication. J Virol (2004) 1.36
Autophosphorylation of the Escherichia coli protein kinase Wzc regulates tyrosine phosphorylation of Ugd, a UDP-glucose dehydrogenase. J Biol Chem (2003) 1.35
Domain 3 of non-structural protein 5A from hepatitis C virus is natively unfolded. Biochem Biophys Res Commun (2009) 1.34
Hepatitis C virus core protein is a dimeric alpha-helical protein exhibiting membrane protein features. J Virol (2005) 1.34
Recent advances in solution NMR: fast methods and heteronuclear direct detection. Chemphyschem (2009) 1.34
Quantitative determination of the conformational properties of partially folded and intrinsically disordered proteins using NMR dipolar couplings. Structure (2009) 1.33
Hepatitis C virus nonstructural protein 4B: a journey into unexplored territory. Rev Med Virol (2010) 1.32
Direct observation of the dynamic process underlying allosteric signal transmission. J Am Chem Soc (2009) 1.32
BEST-TROSY experiments for time-efficient sequential resonance assignment of large disordered proteins. J Biomol NMR (2013) 1.32
Identification and characterization of a fructose phosphotransferase system in Bifidobacterium breve UCC2003. Appl Environ Microbiol (2006) 1.32
The C terminus of hepatitis C virus NS4A encodes an electrostatic switch that regulates NS5A hyperphosphorylation and viral replication. J Virol (2007) 1.32
Identification of a gene cluster enabling Lactobacillus casei BL23 to utilize myo-inositol. Appl Environ Microbiol (2007) 1.29
A diet based on high-heat-treated foods promotes risk factors for diabetes mellitus and cardiovascular diseases. Am J Clin Nutr (2010) 1.28
Optimized 3D-NMR sampling for resonance assignment of partially unfolded proteins. J Magn Reson (2007) 1.28
Intrinsic disorder in measles virus nucleocapsids. Proc Natl Acad Sci U S A (2011) 1.27
Fragile X-related protein FXR1P regulates proinflammatory cytokine tumor necrosis factor expression at the post-transcriptional level. J Biol Chem (2004) 1.26
Protein folding and unfolding studied at atomic resolution by fast two-dimensional NMR spectroscopy. Proc Natl Acad Sci U S A (2007) 1.26
Antitermination by GlpP, catabolite repression via CcpA and inducer exclusion triggered by P-GlpK dephosphorylation control Bacillus subtilis glpFK expression. Mol Microbiol (2002) 1.26
Correlations between carbon metabolism and virulence in bacteria. Contrib Microbiol (2009) 1.25
Transmembrane domains of hepatitis C virus envelope glycoproteins: residues involved in E1E2 heterodimerization and involvement of these domains in virus entry. J Virol (2006) 1.25
Quantitative description of backbone conformational sampling of unfolded proteins at amino acid resolution from NMR residual dipolar couplings. J Am Chem Soc (2009) 1.24
Amphipathic alpha-helix AH2 is a major determinant for the oligomerization of hepatitis C virus nonstructural protein 4B. J Virol (2010) 1.23
Pyrophosphate-producing protein dephosphorylation by HPr kinase/phosphorylase: a relic of early life? Proc Natl Acad Sci U S A (2002) 1.23
Flexible-meccano: a tool for the generation of explicit ensemble descriptions of intrinsically disordered proteins and their associated experimental observables. Bioinformatics (2012) 1.22
Describing intrinsically disordered proteins at atomic resolution by NMR. Curr Opin Struct Biol (2013) 1.22
Unusual multiple recoding events leading to alternative forms of hepatitis C virus core protein from genotype 1b. J Biol Chem (2003) 1.22
Simultaneous determination of protein backbone structure and dynamics from residual dipolar couplings. J Am Chem Soc (2006) 1.22
The hepatitis C virus Core protein is a potent nucleic acid chaperone that directs dimerization of the viral (+) strand RNA in vitro. Nucleic Acids Res (2004) 1.22
NMR structure and ion channel activity of the p7 protein from hepatitis C virus. J Biol Chem (2010) 1.21
HCVDB: hepatitis C virus sequences database. Appl Bioinformatics (2004) 1.21
Basic residues in hypervariable region 1 of hepatitis C virus envelope glycoprotein e2 contribute to virus entry. J Virol (2005) 1.21
Solid state NMR sequential resonance assignments and conformational analysis of the 2x10.4 kDa dimeric form of the Bacillus subtilis protein Crh. J Biomol NMR (2003) 1.21
Domain conformation of tau protein studied by solution small-angle X-ray scattering. Biochemistry (2008) 1.20
Recovering lost magnetization: polarization enhancement in biomolecular NMR. J Biomol NMR (2010) 1.20
X-ray structure of a bifunctional protein kinase in complex with its protein substrate HPr. Proc Natl Acad Sci U S A (2002) 1.20
Structure of the vesicular stomatitis virus N⁰-P complex. PLoS Pathog (2011) 1.20
Effects of a high-fat diet on energy metabolism and ROS production in rat liver. J Hepatol (2010) 1.20
Mapping the potential energy landscape of intrinsically disordered proteins at amino acid resolution. J Am Chem Soc (2012) 1.19
A cell-cell communication system regulates protease production during sporulation in bacteria of the Bacillus cereus group. Mol Microbiol (2011) 1.19
Enhanced conformational space sampling improves the prediction of chemical shifts in proteins. J Am Chem Soc (2010) 1.18
Structural characterization of alpha-synuclein in an aggregation prone state. Protein Sci (2009) 1.18
A region of the Epstein-Barr virus (EBV) mRNA export factor EB2 containing an arginine-rich motif mediates direct binding to RNA. J Biol Chem (2003) 1.17
Structural biology: Proteins in dynamic equilibrium. Nature (2010) 1.16
An amphipathic alpha-helix at the C terminus of hepatitis C virus nonstructural protein 4B mediates membrane association. J Virol (2009) 1.16
Defining conformational ensembles of intrinsically disordered and partially folded proteins directly from chemical shifts. J Am Chem Soc (2010) 1.15
Identification of new functional regions in hepatitis C virus envelope glycoprotein E2. J Virol (2010) 1.15
Quantitative conformational analysis of partially folded proteins from residual dipolar couplings: application to the molecular recognition element of Sendai virus nucleoprotein. J Am Chem Soc (2008) 1.15
Memory T-cell-mediated immune responses specific to an alternative core protein in hepatitis C virus infection. J Virol (2004) 1.14
Anisotropic small amplitude Peptide plane dynamics in proteins from residual dipolar couplings. J Am Chem Soc (2004) 1.14