Describing intrinsically disordered proteins at atomic resolution by NMR.

Classification of intrinsically disordered regions and proteins. Chem Rev (2014) 2.48

pE-DB: a database of structural ensembles of intrinsically disordered and of unfolded proteins. Nucleic Acids Res (2013) 1.13

Physicochemical properties of cells and their effects on intrinsically disordered proteins (IDPs). Chem Rev (2014) 1.10

Relating sequence encoded information to form and function of intrinsically disordered proteins. Curr Opin Struct Biol (2015) 1.06

Single-molecule spectroscopy reveals polymer effects of disordered proteins in crowded environments. Proc Natl Acad Sci U S A (2014) 1.03

Insights into Coupled Folding and Binding Mechanisms from Kinetic Studies. J Biol Chem (2016) 0.97

Cooperative unfolding of compact conformations of the intrinsically disordered protein osteopontin. Biochemistry (2013) 0.92

Atomic resolution description of the interaction between the nucleoprotein and phosphoprotein of Hendra virus. PLoS Pathog (2013) 0.83

Multi-scale ensemble modeling of modular proteins with intrinsically disordered linker regions: application to p53. Biophys J (2014) 0.82

DeepCNF-D: Predicting Protein Order/Disorder Regions by Weighted Deep Convolutional Neural Fields. Int J Mol Sci (2015) 0.82

Disorder-to-Order Transition of an Active-Site Loop Mediates the Allosteric Activation of Sortase A. Biophys J (2015) 0.82

Linkage-specific conformational ensembles of non-canonical polyubiquitin chains. Phys Chem Chem Phys (2016) 0.82

Mechanisms of amyloid formation revealed by solution NMR. Prog Nucl Magn Reson Spectrosc (2015) 0.80

High-resolution structural characterization of Noxa, an intrinsically disordered protein, by microsecond molecular dynamics simulations. Mol Biosyst (2015) 0.80

A six-dimensional alpha proton detection-based APSY experiment for backbone assignment of intrinsically disordered proteins. J Biomol NMR (2014) 0.80

The dynamic duo: combining NMR and small angle scattering in structural biology. Protein Sci (2014) 0.79

Discriminating binding mechanisms of an intrinsically disordered protein via a multi-state coarse-grained model. J Chem Phys (2014) 0.79

Intrinsically disordered energy landscapes. Sci Rep (2015) 0.78

Conformational Dynamics of the Partially Disordered Yeast Transcription Factor GCN4. J Chem Theory Comput (2013) 0.77

Unveiling Inherent Degeneracies in Determining Population-Weighted Ensembles of Interdomain Orientational Distributions Using NMR Residual Dipolar Couplings: Application to RNA Helix Junction Helix Motifs. J Phys Chem B (2015) 0.77

Behaviour of intrinsically disordered proteins in protein-protein complexes with an emphasis on fuzziness. Cell Mol Life Sci (2017) 0.77

New opportunities for tensor-free calculations of residual dipolar couplings for the study of protein dynamics. J Biomol NMR (2014) 0.76

Disorder transitions and conformational diversity cooperatively modulate biological function in proteins. Protein Sci (2016) 0.76

There is Diversity in Disorder-"In all Chaos there is a Cosmos, in all Disorder a Secret Order". Front Mol Biosci (2016) 0.76

Network representation of protein interactions: Theory of graph description and analysis. Protein Sci (2016) 0.75

The Ramachandran Number: An Order Parameter for Protein Geometry. PLoS One (2016) 0.75

Mechanism and rate constants of the Cdc42 GTPase binding with intrinsically disordered effectors. Proteins (2016) 0.75

Conformational characterization of the intrinsically disordered protein Chibby: Interplay between structural elements in target recognition. Protein Sci (2016) 0.75

AUCpreD: proteome-level protein disorder prediction by AUC-maximized deep convolutional neural fields. Bioinformatics (2016) 0.75

Simultaneous quantification of protein order and disorder. Nat Chem Biol (2017) 0.75

Distribution of Pico- and Nanosecond Motions in Disordered Proteins from Nuclear Spin Relaxation. Biophys J (2015) 0.75

Deconvoluting Protein (Un)folding Structural Ensembles Using X-Ray Scattering, Nuclear Magnetic Resonance Spectroscopy and Molecular Dynamics Simulation. PLoS One (2015) 0.75

SilE is an intrinsically disordered periplasmic "molecular sponge" involved in bacterial silver resistance. Mol Microbiol (2016) 0.75

Can proteins be intrinsically disordered inside a membrane? Intrinsically Disord Proteins (2015) 0.75

Modern Technologies of Solution Nuclear Magnetic Resonance Spectroscopy for Three-dimensional Structure Determination of Proteins Open Avenues for Life Scientists. Comput Struct Biotechnol J (2017) 0.75

Functions of intrinsic disorder in transmembrane proteins. Cell Mol Life Sci (2017) 0.75

Predictions of Backbone Dynamics in Intrinsically Disordered Proteins Using De Novo Fragment-Based Protein Structure Predictions. Sci Rep (2017) 0.75

A J-modulated protonless NMR experiment characterizes the conformational ensemble of the intrinsically disordered protein WIP. J Biomol NMR (2016) 0.75

HN-NCA heteronuclear TOCSY-NH experiment for (1)H(N) and (15)N sequential correlations in ((13)C, (15)N) labelled intrinsically disordered proteins. J Biomol NMR (2015) 0.75

Structural characterization of flexible proteins using small-angle X-ray scattering. J Am Chem Soc (2007) 6.53

The cap-snatching endonuclease of influenza virus polymerase resides in the PA subunit. Nature (2009) 5.06

The structural basis for cap binding by influenza virus polymerase subunit PB2. Nat Struct Mol Biol (2008) 4.33

Crystal structure of the rabies virus nucleoprotein-RNA complex. Science (2006) 3.48

Structure and nuclear import function of the C-terminal domain of influenza virus polymerase PB2 subunit. Nat Struct Mol Biol (2007) 3.13

Host determinant residue lysine 627 lies on the surface of a discrete, folded domain of influenza virus polymerase PB2 subunit. PLoS Pathog (2008) 2.60

Identification of slow correlated motions in proteins using residual dipolar and hydrogen-bond scalar couplings. Proc Natl Acad Sci U S A (2005) 2.35

A structural model for unfolded proteins from residual dipolar couplings and small-angle x-ray scattering. Proc Natl Acad Sci U S A (2005) 2.28

Paramyxovirus mRNA editing, the "rule of six" and error catastrophe: a hypothesis. J Gen Virol (2005) 2.19

Structure of tumor suppressor p53 and its intrinsically disordered N-terminal transactivation domain. Proc Natl Acad Sci U S A (2008) 2.14

Ebola virus matrix protein VP40 interaction with human cellular factors Tsg101 and Nedd4. J Mol Biol (2003) 2.11

A quasi-atomic model of human adenovirus type 5 capsid. EMBO J (2005) 2.09

Exploring multiple timescale motions in protein GB3 using accelerated molecular dynamics and NMR spectroscopy. J Am Chem Soc (2007) 2.04

Nuclear traffic of influenza virus proteins and ribonucleoprotein complexes. Virus Res (2006) 1.96

Crystal structure of the M1 protein-binding domain of the influenza A virus nuclear export protein (NEP/NS2). EMBO J (2003) 1.95

Influenza A virus polymerase: structural insights into replication and host adaptation mechanisms. J Biol Chem (2010) 1.89

Defining long-range order and local disorder in native alpha-synuclein using residual dipolar couplings. J Am Chem Soc (2005) 1.75

Three-dimensional model for the isolated recombinant influenza virus polymerase heterotrimer. Nucleic Acids Res (2007) 1.62

Toward a unified representation of protein structural dynamics in solution. J Am Chem Soc (2009) 1.55

Cellular glycosaminoglycans and low density lipoprotein receptor are involved in hepatitis C virus adsorption. J Med Virol (2002) 1.55

The 12 A structure of trypsin-treated measles virus N-RNA. J Mol Biol (2004) 1.52

Highly populated turn conformations in natively unfolded tau protein identified from residual dipolar couplings and molecular simulation. J Am Chem Soc (2007) 1.49

Heparan sulfate-mediated binding of infectious dengue virus type 2 and yellow fever virus. Virology (2002) 1.48

A thermodynamic switch modulates abscisic acid receptor sensitivity. EMBO J (2011) 1.44

NMR characterization of long-range order in intrinsically disordered proteins. J Am Chem Soc (2010) 1.43

Oligomerization and polymerization of the filovirus matrix protein VP40. Virology (2003) 1.42

Insights into transcription initiation and termination from the electron microscopy structure of yeast RNA polymerase III. Mol Cell (2007) 1.40

Structural basis of dynamic glycine receptor clustering by gephyrin. EMBO J (2004) 1.39

Morphology of Marburg virus NP-RNA. Virology (2002) 1.38

Protein conformational flexibility from structure-free analysis of NMR dipolar couplings: quantitative and absolute determination of backbone motion in ubiquitin. Angew Chem Int Ed Engl (2009) 1.38

Structural analysis of specific metal chelating inhibitor binding to the endonuclease domain of influenza pH1N1 (2009) polymerase. PLoS Pathog (2012) 1.34

Quantitative determination of the conformational properties of partially folded and intrinsically disordered proteins using NMR dipolar couplings. Structure (2009) 1.33

Rabies virus chaperone: identification of the phosphoprotein peptide that keeps nucleoprotein soluble and free from non-specific RNA. Virology (2006) 1.29

Intrinsic disorder in measles virus nucleocapsids. Proc Natl Acad Sci U S A (2011) 1.27

Unphosphorylated rhabdoviridae phosphoproteins form elongated dimers in solution. Biochemistry (2007) 1.26

Bacteriorhodopsin/amphipol complexes: structural and functional properties. Biophys J (2008) 1.24

Quantitative description of backbone conformational sampling of unfolded proteins at amino acid resolution from NMR residual dipolar couplings. J Am Chem Soc (2009) 1.24

Flexible-meccano: a tool for the generation of explicit ensemble descriptions of intrinsically disordered proteins and their associated experimental observables. Bioinformatics (2012) 1.22

Simultaneous determination of protein backbone structure and dynamics from residual dipolar couplings. J Am Chem Soc (2006) 1.22

Interaction of influenza virus proteins with nucleosomes. Virology (2005) 1.21

Domain conformation of tau protein studied by solution small-angle X-ray scattering. Biochemistry (2008) 1.20

Structure of the vesicular stomatitis virus N⁰-P complex. PLoS Pathog (2011) 1.20

Nucleocytoplasmic shuttling of the rabies virus P protein requires a nuclear localization signal and a CRM1-dependent nuclear export signal. Virology (2005) 1.20

Mapping the potential energy landscape of intrinsically disordered proteins at amino acid resolution. J Am Chem Soc (2012) 1.19

Mutational and metal binding analysis of the endonuclease domain of the influenza virus polymerase PA subunit. J Virol (2010) 1.19

Rabies virus transcription and replication. Adv Virus Res (2011) 1.19

Enhanced conformational space sampling improves the prediction of chemical shifts in proteins. J Am Chem Soc (2010) 1.18

Structural characterization of alpha-synuclein in an aggregation prone state. Protein Sci (2009) 1.18

Modular organization of rabies virus phosphoprotein. J Mol Biol (2009) 1.17

Structural biology: Proteins in dynamic equilibrium. Nature (2010) 1.16

Long-term shedding of infectious epstein-barr virus after infectious mononucleosis. J Infect Dis (2005) 1.15

Defining conformational ensembles of intrinsically disordered and partially folded proteins directly from chemical shifts. J Am Chem Soc (2010) 1.15

Quantitative conformational analysis of partially folded proteins from residual dipolar couplings: application to the molecular recognition element of Sendai virus nucleoprotein. J Am Chem Soc (2008) 1.15

Structure and function of the C-terminal domain of the polymerase cofactor of rabies virus. J Mol Biol (2004) 1.15

Anisotropic small amplitude Peptide plane dynamics in proteins from residual dipolar couplings. J Am Chem Soc (2004) 1.14

pE-DB: a database of structural ensembles of intrinsically disordered and of unfolded proteins. Nucleic Acids Res (2013) 1.13

Three-dimensional structure of canine adenovirus serotype 2 capsid. J Virol (2008) 1.13

Conformational changes specific for pseudophosphorylation at serine 262 selectively impair binding of tau to microtubules. Biochemistry (2009) 1.12

Interaction of the C-terminal domains of sendai virus N and P proteins: comparison of polymerase-nucleocapsid interactions within the paramyxovirus family. J Virol (2007) 1.11

Solution structure of the C-terminal X domain of the measles virus phosphoprotein and interaction with the intrinsically disordered C-terminal domain of the nucleoprotein. J Mol Recognit (2010) 1.10

Solution structure of the C-terminal nucleoprotein-RNA binding domain of the vesicular stomatitis virus phosphoprotein. J Mol Biol (2008) 1.10

Site-specific measurement of slow motions in proteins. J Am Chem Soc (2011) 1.10

An archaeal peptidase assembles into two different quaternary structures: A tetrahedron and a giant octahedron. J Biol Chem (2006) 1.09

Exploring free-energy landscapes of intrinsically disordered proteins at atomic resolution using NMR spectroscopy. Chem Rev (2014) 1.08

Monomeric nucleoprotein of influenza A virus. PLoS Pathog (2013) 1.07

Conformational distributions of unfolded polypeptides from novel NMR techniques. J Chem Phys (2008) 1.06

Structure and dynamics of the nucleocapsid-binding domain of the Sendai virus phosphoprotein in solution. Virology (2004) 1.06

Intrinsically disordered proteins: from sequence and conformational properties toward drug discovery. Chembiochem (2012) 1.03

Testing the validity of ensemble descriptions of intrinsically disordered proteins. Proc Natl Acad Sci U S A (2014) 1.02

Side-chain chi(1) conformations in urea-denatured ubiquitin and protein G from (3)J coupling constants and residual dipolar couplings. J Am Chem Soc (2010) 1.02

Simultaneous definition of high resolution protein structure and backbone conformational dynamics using NMR residual dipolar couplings. Chemphyschem (2007) 1.02

ProtSA: a web application for calculating sequence specific protein solvent accessibilities in the unfolded ensemble. BMC Bioinformatics (2009) 1.01

Sequence-specific solvent accessibilities of protein residues in unfolded protein ensembles. Biophys J (2006) 1.00

The crystal structure of the Epstein-Barr virus protease shows rearrangement of the processed C terminus. J Mol Biol (2002) 1.00

Structure of the dimerization domain of the rabies virus phosphoprotein. J Virol (2010) 1.00

Solution structure and dynamics of Crh, the Bacillus subtilis catabolite repression HPr. J Mol Biol (2002) 0.99

Structural dynamics of protein backbone phi angles: extended molecular dynamics simulations versus experimental (3) J scalar couplings. J Biomol NMR (2009) 0.98

Towards a robust description of intrinsic protein disorder using nuclear magnetic resonance spectroscopy. Mol Biosyst (2011) 0.98

The C-terminal domains of adenovirus serotype 5 protein IX assemble into an antiparallel structure on the facets of the capsid. J Virol (2008) 0.98

Anisotropic collective motion contributes to nuclear spin relaxation in crystalline proteins. J Am Chem Soc (2010) 0.98

Chemical modification of nucleotide bases and mRNA editing depend on hexamer or nucleoprotein phase in Sendai virus nucleocapsids. RNA (2002) 0.98

Isolation and characterisation of the rabies virus N degrees-P complex produced in insect cells. Virology (2003) 0.97

Visualizing the molecular recognition trajectory of an intrinsically disordered protein using multinuclear relaxation dispersion NMR. J Am Chem Soc (2015) 0.97

Direct observation of dipolar couplings and hydrogen bonds across a beta-hairpin in 8 M urea. J Am Chem Soc (2007) 0.96

Nuclear magnetic resonance provides a quantitative description of protein conformational flexibility on physiologically important time scales. Biochemistry (2011) 0.96

Structure-based discovery of the novel antiviral properties of naproxen against the nucleoprotein of influenza A virus. Antimicrob Agents Chemother (2013) 0.96

Nucleoprotein-RNA orientation in the measles virus nucleocapsid by three-dimensional electron microscopy. J Virol (2010) 0.95

Binding of rabies virus polymerase cofactor to recombinant circular nucleoprotein-RNA complexes. J Mol Biol (2009) 0.95

Structural studies on the Ebola virus matrix protein VP40 indicate that matrix proteins of enveloped RNA viruses are analogues but not homologues. FEMS Microbiol Lett (2004) 0.95

Site-specific backbone dynamics from a crystalline protein by solid-state NMR spectroscopy. J Am Chem Soc (2004) 0.95

Amino acid bulkiness defines the local conformations and dynamics of natively unfolded alpha-synuclein and tau. J Am Chem Soc (2007) 0.94

The 100K-chaperone protein from adenovirus serotype 2 (Subgroup C) assists in trimerization and nuclear localization of hexons from subgroups C and B adenoviruses. J Mol Biol (2005) 0.94

Relaxation-based structure refinement and backbone molecular dynamics of the dynein motor domain-associated light chain. Biochemistry (2003) 0.94