Published in J Biol Chem on May 21, 2002
Fast anterograde transport of herpes simplex virus: role for the amyloid precursor protein of alzheimer's disease. Aging Cell (2003) 1.94
JNK3 perpetuates metabolic stress induced by Aβ peptides. Neuron (2012) 1.80
The novel cargo Alcadein induces vesicle association of kinesin-1 motor components and activates axonal transport. EMBO J (2007) 1.55
Proteolytic processing of Alzheimer's β-amyloid precursor protein. J Neurochem (2011) 1.50
Regulation of amyloid beta-protein precursor by phosphorylation and protein interactions. J Biol Chem (2008) 1.35
The interactome of the amyloid beta precursor protein family members is shaped by phosphorylation of their intracellular domains. Mol Neurodegener (2009) 1.12
Roles of amyloid precursor protein family members in neuroprotection, stress signaling and aging. Exp Brain Res (2011) 0.93
C-terminal cleavage of the amyloid-beta protein precursor at Asp664: a switch associated with Alzheimer's disease. J Alzheimers Dis (2008) 0.93
Co-localization of the amyloid precursor protein and Notch intracellular domains in nuclear transcription factories. Neurobiol Aging (2008) 0.92
Independent pathways downstream of the Wnd/DLK MAPKKK regulate synaptic structure, axonal transport, and injury signaling. J Neurosci (2013) 0.91
Neurodegeneration in Alzheimer disease: role of amyloid precursor protein and presenilin 1 intracellular signaling. J Toxicol (2012) 0.90
XB51 isoforms mediate Alzheimer's beta-amyloid peptide production by X11L (X11-like protein)-dependent and -independent mechanisms. Biochem J (2003) 0.80
Murine cytomegalovirus infection and apoptosis in organotypic retinal cultures. Invest Ophthalmol Vis Sci (2008) 0.80
Loss of c-Jun N-terminal kinase-interacting protein-1 does not affect axonal transport of the amyloid precursor protein or Aβ production. Hum Mol Genet (2013) 0.79
A high affinity RIM-binding protein/Aplip1 interaction prevents the formation of ectopic axonal active zones. Elife (2015) 0.76
The interaction of Kinesin-1 with its adaptor protein JIP1 can be regulated via proteins binding to the JIP1-PTB domain. BMC Cell Biol (2013) 0.75
State-dependent sensory gating in olfactory cortex. Neuron (2005) 2.49
Time-dependent reorganization of the brain components underlying memory retention in trace eyeblink conditioning. J Neurosci (2003) 2.43
The APP intracellular domain forms nuclear multiprotein complexes and regulates the transcription of its own precursor. J Cell Sci (2004) 2.07
Escherichia coli phage-shock protein A (PspA) binds to membrane phospholipids and repairs proton leakage of the damaged membranes. Mol Microbiol (2007) 1.74
A scaffold protein JIP-1b enhances amyloid precursor protein phosphorylation by JNK and its association with kinesin light chain 1. J Biol Chem (2003) 1.65
The novel cargo Alcadein induces vesicle association of kinesin-1 motor components and activates axonal transport. EMBO J (2007) 1.55
Novel cadherin-related membrane proteins, Alcadeins, enhance the X11-like protein-mediated stabilization of amyloid beta-protein precursor metabolism. J Biol Chem (2003) 1.52
Thermophilic ATP synthase has a decamer c-ring: indication of noninteger 10:3 H+/ATP ratio and permissive elastic coupling. Proc Natl Acad Sci U S A (2004) 1.48
Interaction of Alzheimer's beta -amyloid precursor family proteins with scaffold proteins of the JNK signaling cascade. J Biol Chem (2002) 1.46
ATP-driven stepwise rotation of FoF1-ATP synthase. Proc Natl Acad Sci U S A (2005) 1.43
Axle-less F1-ATPase rotates in the correct direction. Science (2008) 1.36
Regulatory interplay between proton motive force, ADP, phosphate, and subunit epsilon in bacterial ATP synthase. J Biol Chem (2006) 1.32
Coordinated metabolism of Alcadein and amyloid beta-protein precursor regulates FE65-dependent gene transactivation. J Biol Chem (2004) 1.26
Endoplasmic reticulum chaperones inhibit the production of amyloid-beta peptides. Biochem J (2007) 1.24
Enhanced amyloidogenic metabolism of the amyloid beta-protein precursor in the X11L-deficient mouse brain. J Biol Chem (2006) 1.19
X11 proteins regulate the translocation of amyloid beta-protein precursor (APP) into detergent-resistant membrane and suppress the amyloidogenic cleavage of APP by beta-site-cleaving enzyme in brain. J Biol Chem (2008) 1.17
Physiological mouse brain Abeta levels are not related to the phosphorylation state of threonine-668 of Alzheimer's APP. PLoS One (2006) 1.14
Suppression of Alzheimer's disease-related phenotypes by expression of heat shock protein 70 in mice. J Neurosci (2011) 1.14
mGluR1 in cerebellar Purkinje cells is required for normal association of temporally contiguous stimuli in classical conditioning. Eur J Neurosci (2002) 1.12
The role of subunit epsilon in the catalysis and regulation of FOF1-ATP synthase. Biochim Biophys Acta (2006) 1.12
Time-limited role of the hippocampus in the memory for trace eyeblink conditioning in mice. Brain Res (2002) 1.09
Endoplasmic reticulum stress-inducible protein, Herp, enhances presenilin-mediated generation of amyloid beta-protein. J Biol Chem (2002) 1.09
Systems consolidation requires postlearning activation of NMDA receptors in the medial prefrontal cortex in trace eyeblink conditioning. J Neurosci (2006) 1.08
Real-time monitoring of conformational dynamics of the epsilon subunit in F1-ATPase. J Biol Chem (2005) 1.07
Alcadein cleavages by amyloid beta-precursor protein (APP) alpha- and gamma-secretases generate small peptides, p3-Alcs, indicating Alzheimer disease-related gamma-secretase dysfunction. J Biol Chem (2009) 1.06
Role of APP phosphorylation in FE65-dependent gene transactivation mediated by AICD. Genes Cells (2006) 1.06
Torque generation and utilization in motor enzyme F0F1-ATP synthase: half-torque F1 with short-sized pushrod helix and reduced ATP Synthesis by half-torque F0F1. J Biol Chem (2011) 1.05
Facilitation of stress-induced phosphorylation of beta-amyloid precursor protein family members by X11-like/Mint2 protein. J Biol Chem (2004) 1.03
Interaction of N-terminal acetyltransferase with the cytoplasmic domain of beta-amyloid precursor protein and its effect on A beta secretion. J Biochem (2005) 1.02
Evaluation of intramitochondrial ATP levels identifies G0/G1 switch gene 2 as a positive regulator of oxidative phosphorylation. Proc Natl Acad Sci U S A (2013) 1.02
Regulation of FE65 nuclear translocation and function by amyloid beta-protein precursor in osmotically stressed cells. J Biol Chem (2008) 1.02
Involvement of prostaglandin E2 in production of amyloid-beta peptides both in vitro and in vivo. J Biol Chem (2007) 1.01
SREC-II, a new member of the scavenger receptor type F family, trans-interacts with SREC-I through its extracellular domain. J Biol Chem (2002) 1.01
Modulation of amyloid precursor protein cleavage by cellular sphingolipids. J Biol Chem (2004) 1.00
Hippocampal CA3 NMDA receptors are crucial for adaptive timing of trace eyeblink conditioned response. J Neurosci (2006) 1.00
Cysteine-rich intestinal protein 2 (CRIP2) acts as a repressor of NF-kappaB-mediated proangiogenic cytokine transcription to suppress tumorigenesis and angiogenesis. Proc Natl Acad Sci U S A (2011) 0.99
Essential arginine residue of the F(o)-a subunit in F(o)F(1)-ATP synthase has a role to prevent the proton shortcut without c-ring rotation in the F(o) proton channel. Biochem J (2010) 0.97
Amyloid-dependent triosephosphate isomerase nitrotyrosination induces glycation and tau fibrillation. Brain (2009) 0.96
ATP synthase that lacks F0a-subunit: isolation, properties, and indication of F0b2-subunits as an anchor rail of a rotating c-ring. J Biol Chem (2004) 0.96
The role of the betaDELSEED-loop of ATP synthase. J Biol Chem (2009) 0.95
A small peptide sequence is sufficient for initiating kinesin-1 activation through part of TPR region of KLC1. Traffic (2012) 0.95
Paths, elongation, and projections of ascending chick embryonic spinal commissural neurons after crossing the floor plate. Brain Res (2008) 0.94
Control of bacteriophage T4 tail lysozyme activity during the infection process. J Mol Biol (2005) 0.94
Activation and stiffness of the inhibited states of F1-ATPase probed by single-molecule manipulation. J Biol Chem (2010) 0.94
Purkinje cell activity during learning a new timing in classical eyeblink conditioning. Brain Res (2003) 0.94
Slow Ca2+ dynamics in pharyngeal muscles in Caenorhabditis elegans during fast pumping. EMBO Rep (2004) 0.94
Alternative processing of γ-secretase substrates in common forms of mild cognitive impairment and Alzheimer's disease: evidence for γ-secretase dysfunction. Ann Neurol (2011) 0.93
Neither helix in the coiled coil region of the axle of F1-ATPase plays a significant role in torque production. Biophys J (2008) 0.93
NMDA receptor-dependent processes in the medial prefrontal cortex are important for acquisition and the early stage of consolidation during trace, but not delay eyeblink conditioning. Learn Mem (2005) 0.93
A new solution structure of ATP synthase subunit c from thermophilic Bacillus PS3, suggesting a local conformational change for H+-translocation. J Mol Biol (2006) 0.92
Role of 14-3-3gamma in FE65-dependent gene transactivation mediated by the amyloid beta-protein precursor cytoplasmic fragment. J Biol Chem (2005) 0.92
Confocal imaging of subcellular Ca2+ concentrations using a dual-excitation ratiometric indicator based on green fluorescent protein. Sci STKE (2002) 0.91
Presenilin 2 mutation accelerates the onset of impairment in trace eyeblink conditioning in a mouse model of Alzheimer's disease overexpressing human mutant amyloid precursor protein. Neurosci Lett (2013) 0.90
Probing conformations of the beta subunit of F0F1-ATP synthase in catalysis. Biochem Biophys Res Commun (2006) 0.90
The presence of phosphate at a catalytic site suppresses the formation of the MgADP-inhibited form of F(1)-ATPase. Eur J Biochem (2002) 0.89
Functional analysis of membranous Fo-a subunit of F1Fo-ATP synthase by in vitro protein synthesis. Biochem J (2012) 0.89
Efficient ATP synthesis by thermophilic Bacillus FoF1-ATP synthase. FEBS J (2011) 0.88
The cytoplasmic adaptor protein X11alpha and extracellular matrix protein Reelin regulate ApoE receptor 2 trafficking and cell movement. FASEB J (2009) 0.88
Intracellular trafficking of the amyloid β-protein precursor (APP) regulated by novel function of X11-like. PLoS One (2011) 0.88
Distributions of gamma-aminobutyric acid immunoreactive and acetylcholinesterase-containing cells in the primary olfactory system in the terrestrial slug Limax marginatus. Zoolog Sci (2003) 0.87
X11-like protein deficiency is associated with impaired conflict resolution in mice. J Neurosci (2009) 0.87
Prostaglandin E2 stimulates the production of amyloid-beta peptides through internalization of the EP4 receptor. J Biol Chem (2009) 0.87
Human CRB2 inhibits gamma-secretase cleavage of amyloid precursor protein by binding to the presenilin complex. J Biol Chem (2010) 0.87
Suppression of APP-containing vesicle trafficking and production of beta-amyloid by AID/DHHC-12 protein. J Neurochem (2009) 0.87
IgSF molecule MDGA1 is involved in radial migration and positioning of a subset of cortical upper-layer neurons. Dev Dyn (2011) 0.86
Kinetic equivalence of transmembrane pH and electrical potential differences in ATP synthesis. J Biol Chem (2012) 0.86
FE65 as a link between VLDLR and APP to regulate their trafficking and processing. Mol Neurodegener (2012) 0.86
The X11L/X11beta/MINT2 and X11L2/X11gamma/MINT3 scaffold proteins shuttle between the nucleus and cytoplasm. Exp Cell Res (2007) 0.85
Dual involvement of G-substrate in motor learning revealed by gene deletion. Proc Natl Acad Sci U S A (2009) 0.85
Transcriptome analysis of distinct mouse strains reveals kinesin light chain-1 splicing as an amyloid-β accumulation modifier. Proc Natl Acad Sci U S A (2014) 0.85
Trace eyeblink conditioning in decerebrate guinea pigs. Eur J Neurosci (2003) 0.85
Neural and molecular mechanisms of microcognition in Limax. Learn Mem (2008) 0.85
The hippocampus plays an important role in eyeblink conditioning with a short trace interval in glutamate receptor subunit delta 2 mutant mice. J Neurosci (2003) 0.84
Membrane-microdomain localization of amyloid β-precursor protein (APP) C-terminal fragments is regulated by phosphorylation of the cytoplasmic Thr668 residue. J Biol Chem (2012) 0.84
The N-methyl-D-aspartate (NMDA)-type glutamate receptor GluRepsilon2 is important for delay and trace eyeblink conditioning in mice. Neurosci Lett (2004) 0.84
Improvement of cognitive function in Alzheimer's disease model mice by genetic and pharmacological inhibition of the EP(4) receptor. J Neurochem (2012) 0.84
Increased amyloidogenic processing of transgenic human APP in X11-like deficient mouse brain. Mol Neurodegener (2010) 0.84
Multiple γ-secretase product peptides are coordinately increased in concentration in the cerebrospinal fluid of a subpopulation of sporadic Alzheimer's disease subjects. Mol Neurodegener (2012) 0.84
Regulation of the physiological function and metabolism of AbetaPP by AbetaPP binding proteins. J Alzheimers Dis (2009) 0.84
UncI protein can mediate ring-assembly of c-subunits of FoF1-ATP synthase in vitro. Biochem Biophys Res Commun (2008) 0.83
Odor-evoked responses in the olfactory center neurons in the terrestrial slug. J Neurobiol (2004) 0.83
Impairment of olfactory discrimination by blockade of nitric oxide activity in the terrestrial slug Limax valentianus. Neurosci Lett (2004) 0.83
Phosphorylation of the amino-terminal region of X11L regulates its interaction with APP. J Neurochem (2009) 0.83
Purkinje cell activity during classical eyeblink conditioning in decerebrate guinea pigs. Brain Res (2005) 0.83
Analysis of the open and closed conformations of the beta subunits in thermophilic F1-ATPase by solution NMR. J Mol Biol (2010) 0.82
Expression and characterization of the Drosophila X11-like/Mint protein during neural development. J Neurochem (2002) 0.82
In vitro odor-aversion conditioning in a terrestrial mollusk. J Neurophysiol (2006) 0.82
Classical eyeblink conditioning in decerebrate guinea pigs. Eur J Neurosci (2002) 0.82
Evidence against roles for phorbol binding protein Munc13-1, ADAM adaptor Eve-1, or vesicle trafficking phosphoproteins Munc18 or NSF as phospho-state-sensitive modulators of phorbol/PKC-activated Alzheimer APP ectodomain shedding. Mol Neurodegener (2007) 0.81
Role of hippocampal NMDA receptors in trace eyeblink conditioning. Brain Res (2005) 0.81
Early impairment in a water-finding test in a longitudinal study of the Tg2576 mouse model of Alzheimer's disease. Brain Res (2012) 0.81
Inhibition of MAO-A and stimulation of behavioural activities in mice by the inactive prodrug form of the anti-influenza agent oseltamivir. Br J Pharmacol (2013) 0.81
Simple and direct assembly of kymographs from movies using KYMOMAKER. Traffic (2013) 0.81
Significance of the epsilon subunit in the thiol modulation of chloroplast ATP synthase. Biochem Biophys Res Commun (2004) 0.81
Purification and functional reconstitution of a seven-subunit mrp-type na+/h+ antiporter. J Bacteriol (2013) 0.81