Published in EMBO J on June 03, 2002
The nuclear pore complex: bridging nuclear transport and gene regulation. Nat Rev Mol Cell Biol (2010) 3.19
Exp5 exports eEF1A via tRNA from nuclei and synergizes with other transport pathways to confine translation to the cytoplasm. EMBO J (2002) 3.03
The nuclear pore complex and nuclear transport. Cold Spring Harb Perspect Biol (2010) 2.71
Systematic kinetic analysis of mitotic dis- and reassembly of the nuclear pore in living cells. J Cell Biol (2008) 2.30
tRNAs promote nuclear import of HIV-1 intracellular reverse transcription complexes. PLoS Biol (2006) 2.28
Characterisation of the passive permeability barrier of nuclear pore complexes. EMBO J (2009) 2.21
Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization. Cell (2015) 2.17
Flexible phenylalanine-glycine nucleoporins as entropic barriers to nucleocytoplasmic transport. Proc Natl Acad Sci U S A (2006) 2.16
NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1. Nat Struct Mol Biol (2010) 2.12
A bimodal distribution of two distinct categories of intrinsically disordered structures with separate functions in FG nucleoporins. Mol Cell Proteomics (2010) 2.09
Crystal structure of the M1 protein-binding domain of the influenza A virus nuclear export protein (NEP/NS2). EMBO J (2003) 1.95
Maturation of eukaryotic ribosomes: acquisition of functionality. Trends Biochem Sci (2010) 1.93
Artificial nanopores that mimic the transport selectivity of the nuclear pore complex. Nature (2008) 1.89
Exportin 6: a novel nuclear export receptor that is specific for profilin.actin complexes. EMBO J (2003) 1.89
Flexible gates: dynamic topologies and functions for FG nucleoporins in nucleocytoplasmic transport. Eukaryot Cell (2009) 1.81
Nuclear import of HIV-1 intracellular reverse transcription complexes is mediated by importin 7. EMBO J (2003) 1.80
A pre-ribosome-associated HEAT-repeat protein is required for export of both ribosomal subunits. Genes Dev (2004) 1.76
Surveillance of nuclear-restricted pre-ribosomes within a subnucleolar region of Saccharomyces cerevisiae. EMBO J (2006) 1.73
Autonomy and robustness of translocation through the nuclear pore complex: a single-molecule study. J Cell Biol (2008) 1.57
Distinct functional domains within nucleoporins Nup153 and Nup98 mediate transcription-dependent mobility. Mol Biol Cell (2004) 1.54
STRADalpha regulates LKB1 localization by blocking access to importin-alpha, and by association with Crm1 and exportin-7. Mol Biol Cell (2008) 1.54
Nuclear envelope breakdown in starfish oocytes proceeds by partial NPC disassembly followed by a rapidly spreading fenestration of nuclear membranes. J Cell Biol (2003) 1.52
A novel splicing regulator shares a nuclear import pathway with SR proteins. EMBO J (2003) 1.51
Nup98 localizes to both nuclear and cytoplasmic sides of the nuclear pore and binds to two distinct nucleoporin subcomplexes. Mol Biol Cell (2003) 1.51
Vertebrate Nup53 interacts with the nuclear lamina and is required for the assembly of a Nup93-containing complex. Mol Biol Cell (2005) 1.49
Towards reconciling structure and function in the nuclear pore complex. Histochem Cell Biol (2008) 1.45
Arx1 is a nuclear export receptor for the 60S ribosomal subunit in yeast. Mol Biol Cell (2007) 1.44
Nuclear mRNA export requires specific FG nucleoporins for translocation through the nuclear pore complex. J Cell Biol (2007) 1.44
Efficiency, selectivity, and robustness of nucleocytoplasmic transport. PLoS Comput Biol (2007) 1.39
Biology and biophysics of the nuclear pore complex and its components. Int Rev Cell Mol Biol (2008) 1.39
Promiscuous interactions and protein disaggregases determine the material state of stress-inducible RNP granules. Elife (2015) 1.34
P granules extend the nuclear pore complex environment in the C. elegans germ line. J Cell Biol (2011) 1.34
HIV infection of non-dividing cells: a divisive problem. Retrovirology (2006) 1.33
An in vitro assay for entry into cilia reveals unique properties of the soluble diffusion barrier. J Cell Biol (2013) 1.31
Influence of cargo size on Ran and energy requirements for nuclear protein import. J Cell Biol (2002) 1.30
Karyopherins in nuclear pore biogenesis: a role for Kap121p in the assembly of Nup53p into nuclear pore complexes. J Cell Biol (2002) 1.29
Nucleo-cytoplasmic partitioning of proteins in plants: implications for the regulation of environmental and developmental signalling. Curr Genet (2003) 1.28
Amyloid-like interactions within nucleoporin FG hydrogels. Proc Natl Acad Sci U S A (2010) 1.26
Integrase interacts with nucleoporin NUP153 to mediate the nuclear import of human immunodeficiency virus type 1. J Virol (2009) 1.26
The yeast nuclear pore complex and transport through it. Genetics (2012) 1.26
ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure. Cell (2016) 1.26
Venezuelan equine Encephalitis virus capsid protein forms a tetrameric complex with CRM1 and importin alpha/beta that obstructs nuclear pore complex function. J Virol (2010) 1.25
Binding dynamics of structural nucleoporins govern nuclear pore complex permeability and may mediate channel gating. Mol Cell Biol (2003) 1.24
FG/FxFG as well as GLFG repeats form a selective permeability barrier with self-healing properties. EMBO J (2009) 1.22
Exportin 4 mediates a novel nuclear import pathway for Sox family transcription factors. J Cell Biol (2009) 1.22
The FG-repeat asymmetry of the nuclear pore complex is dispensable for bulk nucleocytoplasmic transport in vivo. J Cell Biol (2004) 1.20
Single-molecule measurements of importin alpha/cargo complex dissociation at the nuclear pore. Proc Natl Acad Sci U S A (2008) 1.17
Intramolecular cohesion of coils mediated by phenylalanine--glycine motifs in the natively unfolded domain of a nucleoporin. PLoS Comput Biol (2008) 1.16
Charge as a selection criterion for translocation through the nuclear pore complex. PLoS Comput Biol (2010) 1.13
Effect of charge, hydrophobicity, and sequence of nucleoporins on the translocation of model particles through the nuclear pore complex. Proc Natl Acad Sci U S A (2013) 1.11
Metastable network model of protein transport through nuclear pores. Biophys J (2004) 1.11
Identification of the nuclear localization and export signals of high risk HPV16 E7 oncoprotein. Virology (2008) 1.11
Ultrathin nucleoporin phenylalanine-glycine repeat films and their interaction with nuclear transport receptors. EMBO Rep (2010) 1.10
Biological hydrogels as selective diffusion barriers. Trends Cell Biol (2011) 1.10
Single molecule study of the intrinsically disordered FG-repeat nucleoporin 153. Biophys J (2011) 1.09
Cargo surface hydrophobicity is sufficient to overcome the nuclear pore complex selectivity barrier. EMBO J (2009) 1.09
Capturing directed molecular motion in the nuclear pore complex of live cells. Proc Natl Acad Sci U S A (2012) 1.07
Looking beyond the Wnt pathway for the deep nature of β-catenin. EMBO Rep (2013) 1.06
From the trap to the basket: getting to the bottom of the nuclear pore complex. Chromosoma (2006) 1.06
Transport-related structures and processes of the nuclear pore complex studied through molecular dynamics. Structure (2009) 1.04
Nuclear accumulation of plasmid DNA can be enhanced by non-selective gating of the nuclear pore. Nucleic Acids Res (2007) 1.03
Biochemical characterization of the Ran-RanBP1-RanGAP system: are RanBP proteins and the acidic tail of RanGAP required for the Ran-RanGAP GTPase reaction? Mol Cell Biol (2003) 1.02
Adenovirus core protein pVII is translocated into the nucleus by multiple import receptor pathways. J Virol (2006) 1.02
Simulations of nuclear pore transport yield mechanistic insights and quantitative predictions. Proc Natl Acad Sci U S A (2011) 1.01
Next generation organelles: structure and role of germ granules in the germline. Mol Reprod Dev (2012) 1.01
The strategy for coupling the RanGTP gradient to nuclear protein export. Proc Natl Acad Sci U S A (2003) 1.00
Brownian dynamics simulation of nucleocytoplasmic transport: a coarse-grained model for the functional state of the nuclear pore complex. PLoS Comput Biol (2011) 0.99
Nup98 FG domains from diverse species spontaneously phase-separate into particles with nuclear pore-like permselectivity. Elife (2015) 0.98
Crystallographic and biochemical analysis of the Ran-binding zinc finger domain. J Mol Biol (2009) 0.97
Nup153 affects entry of messenger and ribosomal ribonucleoproteins into the nuclear basket during export. Mol Biol Cell (2005) 0.97
The export receptor Crm1 forms a dimer to promote nuclear export of HIV RNA. Elife (2014) 0.94
Single-molecule studies of nucleocytoplasmic transport: from one dimension to three dimensions. Integr Biol (Camb) (2011) 0.94
Biophysical coarse-grained modeling provides insights into transport through the nuclear pore complex. Biophys J (2011) 0.94
Nucleocytoplasmic transport: a role for nonspecific competition in karyopherin-nucleoporin interactions. Mol Cell Proteomics (2012) 0.93
Modulation of nuclear pore topology by transport modifiers. Biophys J (2003) 0.92
Diffusion and retention are major determinants of protein targeting to the inner nuclear membrane. J Cell Biol (2015) 0.91
Functionalization of a nanopore: the nuclear pore complex paradigm. Biochim Biophys Acta (2009) 0.90
The nuclear pore complex--structure and function at a glance. J Cell Sci (2015) 0.89
Macromolecular transport between the nucleus and the cytoplasm: Advances in mechanism and emerging links to disease. Biochim Biophys Acta (2014) 0.89
Atomic force microscopy visualises a hydrophobic meshwork in the central channel of the nuclear pore. Pflugers Arch (2007) 0.88
Higher nucleoporin-Importinβ affinity at the nuclear basket increases nucleocytoplasmic import. PLoS One (2013) 0.88
Defective nuclear import of Tpr in Progeria reflects the Ran sensitivity of large cargo transport. J Cell Biol (2013) 0.87
Reengineering ribosome export. Mol Biol Cell (2009) 0.87
Probing a structural model of the nuclear pore complex channel through molecular dynamics. Biophys J (2010) 0.87
Fluorescent recovery after photobleaching (FRAP) analysis of nuclear export rates identifies intrinsic features of nucleocytoplasmic transport. J Biol Chem (2011) 0.87
A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. Elife (2015) 0.87
Intracellular trafficking and subcellular distribution of a large array of HPMA copolymers. Biomacromolecules (2009) 0.87
Cohesiveness tunes assembly and morphology of FG nucleoporin domain meshworks - Implications for nuclear pore permeability. Biophys J (2013) 0.86
Size-dependent leak of soluble and membrane proteins through the yeast nuclear pore complex. Mol Biol Cell (2015) 0.86
Large cargo transport by nuclear pores: implications for the spatial organization of FG-nucleoporins. EMBO J (2013) 0.86
The nuclear localization of low risk HPV11 E7 protein mediated by its zinc binding domain is independent of nuclear import receptors. Virology (2010) 0.86
Formation of a Tap/NXF1 homotypic complex is mediated through the amino-terminal domain of Tap and enhances interaction with nucleoporins. Mol Biol Cell (2007) 0.86
Nuclear transporters in a multinucleated organism: functional and localization analyses in Aspergillus nidulans. Mol Biol Cell (2011) 0.85
Nuclear pore complex protein sequences determine overall copolymer brush structure and function. Biophys J (2014) 0.85
Multiple conserved domains of the nucleoporin Nup124p and its orthologs Nup1p and Nup153 are critical for nuclear import and activity of the fission yeast Tf1 retrotransposon. Mol Biol Cell (2007) 0.85
The conserved Bud20 zinc finger protein is a new component of the ribosomal 60S subunit export machinery. Mol Cell Biol (2012) 0.84
Nucleocytoplasmic shuttling of cytoskeletal proteins: molecular mechanism and biological significance. Int J Cell Biol (2011) 0.84
Nucleocytoplasmic transport: a thermodynamic mechanism. HFSP J (2009) 0.84
Heat-shock stress activates a novel nuclear import pathway mediated by Hikeshi. Nucleus (2012) 0.84
Characterization of the transport signals that mediate the nucleocytoplasmic traffic of low risk HPV11 E7. Virology (2013) 0.84
CRM1 is an export receptor for leucine-rich nuclear export signals. Cell (1997) 18.60
Transport between the cell nucleus and the cytoplasm. Annu Rev Cell Dev Biol (1999) 13.27
Nucleocytoplasmic transport: the soluble phase. Annu Rev Biochem (1998) 10.74
The yeast nuclear pore complex: composition, architecture, and transport mechanism. J Cell Biol (2000) 10.20
Nuclear protein import in permeabilized mammalian cells requires soluble cytoplasmic factors. J Cell Biol (1990) 8.75
Protein import into nuclei: association and dissociation reactions involving transport substrate, transport factors, and nucleoporins. Cell (1995) 6.97
A polypeptide domain that specifies migration of nucleoplasmin into the nucleus. Cell (1982) 6.39
Export of importin alpha from the nucleus is mediated by a specific nuclear transport factor. Cell (1997) 6.28
A novel receptor-mediated nuclear protein import pathway. Cell (1996) 6.04
Transport of proteins and RNAs in and out of the nucleus. Cell (1999) 6.02
TAP, the human homolog of Mex67p, mediates CTE-dependent RNA export from the nucleus. Mol Cell (1998) 5.85
Inhibition of in vitro nuclear transport by a lectin that binds to nuclear pores. J Cell Biol (1987) 5.62
Catalysis of guanine nucleotide exchange on Ran by the mitotic regulator RCC1. Nature (1991) 5.39
Kinetic analysis of translocation through nuclear pore complexes. EMBO J (2001) 5.27
The peptide repeat domain of nucleoporin Nup98 functions as a docking site in transport across the nuclear pore complex. Cell (1995) 4.55
The Mex67p-mediated nuclear mRNA export pathway is conserved from yeast to human. EMBO J (1999) 4.49
Pores for thought: nuclear pore complex proteins. Trends Cell Biol (1994) 4.08
Dominant-negative mutants of importin-beta block multiple pathways of import and export through the nuclear pore complex. EMBO J (1997) 4.06
The C-terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE-bearing RNA substrates. RNA (2000) 3.96
Identification of NTF2, a cytosolic factor for nuclear import that interacts with nuclear pore complex protein p62. J Cell Biol (1995) 3.73
A 41 amino acid motif in importin-alpha confers binding to importin-beta and hence transit into the nucleus. EMBO J (1996) 3.65
Structural basis for the interaction between FxFG nucleoporin repeats and importin-beta in nuclear trafficking. Cell (2000) 3.33
Nuclear pore complex is able to transport macromolecules with diameters of about 39 nm. Mol Biol Cell (2002) 3.20
Nucleocytoplasmic transport enters the atomic age. Curr Opin Cell Biol (2001) 3.06
The conserved amino-terminal domain of hSRP1 alpha is essential for nuclear protein import. EMBO J (1996) 2.90
NTF2 mediates nuclear import of Ran. EMBO J (1998) 2.79
Nuclear pores and nuclear assembly. Curr Opin Cell Biol (2001) 2.74
Importins and exportins: how to get in and out of the nucleus. Trends Biochem Sci (1998) 2.58
Gradient of increasing affinity of importin beta for nucleoporins along the pathway of nuclear import. J Cell Biol (2001) 2.50
Binding of the Mex67p/Mtr2p heterodimer to FXFG, GLFG, and FG repeat nucleoporins is essential for nuclear mRNA export. J Cell Biol (2000) 2.48
Karyopherins and kissing cousins. Trends Cell Biol (1998) 2.42
Ran-unassisted nuclear migration of a 97-kD component of nuclear pore-targeting complex. J Cell Biol (1997) 2.18
Importins fulfil a dual function as nuclear import receptors and cytoplasmic chaperones for exposed basic domains. EMBO J (2002) 2.17
Structural basis for the recognition of a nucleoporin FG repeat by the NTF2-like domain of the TAP/p15 mRNA nuclear export factor. Mol Cell (2001) 2.17
Receptor-mediated substrate translocation through the nuclear pore complex without nucleotide triphosphate hydrolysis. Curr Biol (1999) 2.08
Proteomic analysis of nucleoporin interacting proteins. J Biol Chem (2001) 2.06
The permeability of the nuclear envelope in dividing and nondividing cell cultures. J Cell Biol (1990) 2.06
Characterization of the nuclear protein import mechanism using Ran mutants with altered nucleotide binding specificities. EMBO J (1996) 2.01
The direction of transport through the nuclear pore can be inverted. Proc Natl Acad Sci U S A (1999) 1.99
Importin 13: a novel mediator of nuclear import and export. EMBO J (2001) 1.98
A look at messenger RNP moving through the nuclear pore. Cell (1997) 1.96
Nuclear import of Ran is mediated by the transport factor NTF2. Curr Biol (1999) 1.95
Ran-dependent signal-mediated nuclear import does not require GTP hydrolysis by Ran. J Biol Chem (1998) 1.78
Interaction between NTF2 and xFxFG-containing nucleoporins is required to mediate nuclear import of RanGDP. J Mol Biol (1999) 1.77
Import and export of the nuclear protein import receptor transportin by a mechanism independent of GTP hydrolysis. Curr Biol (1998) 1.69
The translocation of transportin-cargo complexes through nuclear pores is independent of both Ran and energy. Curr Biol (1999) 1.68
Yeast nucleoporins involved in passive nuclear envelope permeability. J Cell Biol (2000) 1.60
A new view of mRNA export: separating the wheat from the chaff. Nat Cell Biol (2001) 1.58
Separate binding sites on nuclear transport factor 2 (NTF2) for GDP-Ran and the phenylalanine-rich repeat regions of nucleoporins p62 and Nsp1p. J Mol Biol (1996) 1.54
Nucleocytoplasmic transport: diffusion channel or phase transition? Curr Biol (2001) 1.00
Functional analysis of the hydrophobic patch on nuclear transport factor 2 involved in interactions with the nuclear pore in vivo. J Biol Chem (2001) 0.98
Selective disruption of nuclear import by a functional mutant nuclear transport carrier. J Cell Biol (2000) 0.97
FG-rich repeats of nuclear pore proteins form a three-dimensional meshwork with hydrogel-like properties. Science (2006) 4.34
A saturated FG-repeat hydrogel can reproduce the permeability properties of nuclear pore complexes. Cell (2007) 3.90
A selective block of nuclear actin export stabilizes the giant nuclei of Xenopus oocytes. Nat Cell Biol (2006) 3.09
Exp5 exports eEF1A via tRNA from nuclei and synergizes with other transport pathways to confine translation to the cytoplasm. EMBO J (2002) 3.03
Characterisation of the passive permeability barrier of nuclear pore complexes. EMBO J (2009) 2.21
Importins fulfil a dual function as nuclear import receptors and cytoplasmic chaperones for exposed basic domains. EMBO J (2002) 2.17
NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1. Nat Struct Mol Biol (2010) 2.12
Crystal structure of the nuclear export receptor CRM1 in complex with Snurportin1 and RanGTP. Science (2009) 2.08
Exportin 6: a novel nuclear export receptor that is specific for profilin.actin complexes. EMBO J (2003) 1.89
Nuclear import of HIV-1 intracellular reverse transcription complexes is mediated by importin 7. EMBO J (2003) 1.80
NDC1: a crucial membrane-integral nucleoporin of metazoan nuclear pore complexes. J Cell Biol (2006) 1.67
The nuclear F-actin interactome of Xenopus oocytes reveals an actin-bundling kinesin that is essential for meiotic cytokinesis. EMBO J (2013) 1.58
The permeability of reconstituted nuclear pores provides direct evidence for the selective phase model. Cell (2012) 1.50
Ran-dependent nuclear export mediators: a structural perspective. EMBO J (2011) 1.42
NuSAP, a mitotic RanGTP target that stabilizes and cross-links microtubules. Mol Biol Cell (2006) 1.37
Systematic analysis of barrier-forming FG hydrogels from Xenopus nuclear pore complexes. EMBO J (2012) 1.27
Amyloid-like interactions within nucleoporin FG hydrogels. Proc Natl Acad Sci U S A (2010) 1.26
FG/FxFG as well as GLFG repeats form a selective permeability barrier with self-healing properties. EMBO J (2009) 1.22
Exportin 4 mediates a novel nuclear import pathway for Sox family transcription factors. J Cell Biol (2009) 1.22
Structural basis for the cytoskeletal association of Bcr-Abl/c-Abl. Mol Cell (2005) 1.21
Nuclear pore complex assembly and maintenance in POM121- and gp210-deficient cells. J Cell Biol (2006) 1.20
Inducible expression of coding and inhibitory RNAs from retargetable genomic loci. Nucleic Acids Res (2009) 1.17
Exportin 7 defines a novel general nuclear export pathway. EMBO J (2004) 1.17
Myelin membrane assembly is driven by a phase transition of myelin basic proteins into a cohesive protein meshwork. PLoS Biol (2013) 1.14
Ultrathin nucleoporin phenylalanine-glycine repeat films and their interaction with nuclear transport receptors. EMBO Rep (2010) 1.10
Structural analysis of large protein complexes using solvent paramagnetic relaxation enhancements. Angew Chem Int Ed Engl (2011) 0.97
Transport of hypoxia-inducible factor HIF-1alpha into the nucleus involves importins 4 and 7. Biochem Biophys Res Commun (2009) 0.90
Structural characterization of nanoscale meshworks within a nucleoporin FG hydrogel. Biomacromolecules (2012) 0.87
Cohesiveness tunes assembly and morphology of FG nucleoporin domain meshworks - Implications for nuclear pore permeability. Biophys J (2013) 0.86
Histones to the cytosol: exportin 7 is essential for normal terminal erythroid nuclear maturation. Blood (2014) 0.83
Correction: Nanobodies: site-specific labeling for super-resolution imaging, rapid epitope-mapping and native protein complex isolation. Elife (2016) 0.75