Association analysis of estrogen receptor alpha gene polymorphisms with cross-sectional geometry of the femoral neck in Caucasian nuclear families.

PubWeight™: 1.03‹?› | Rank: Top 15%

🔗 View Article (PMID 16292600)

Published in Osteoporos Int on November 15, 2005

Authors

Dong-Hai Xiong1, Yao-Zhong Liu, Peng-Yuan Liu, Lan-Juan Zhao, Hong-Wen Deng

Author Affiliations

1: Osteoporosis Research Center and Department of Biomedical Sciences, Creighton University, 601 N 30th St Suite 6787, Omaha, NE 68131, USA.

Articles citing this

Polymorphisms of the low-density lipoprotein receptor-related protein 5 (LRP5) gene are associated with obesity phenotypes in a large family-based association study. J Med Genet (2006) 1.25

Robust and comprehensive analysis of 20 osteoporosis candidate genes by very high-density single-nucleotide polymorphism screen among 405 white nuclear families identified significant association and gene-gene interaction. J Bone Miner Res (2006) 1.24

Association analyses of RANKL/RANK/OPG gene polymorphisms with femoral neck compression strength index variation in Caucasians. Calcif Tissue Int (2009) 0.95

Genome-wide association study for femoral neck bone geometry. J Bone Miner Res (2010) 0.90

The chemokine (C-C-motif) receptor 3 (CCR3) gene is linked and associated with age at menarche in Caucasian females. Hum Genet (2006) 0.89

Sex-specific association of the glucocorticoid receptor gene with extreme BMD. J Bone Miner Res (2008) 0.85

Association analyses of vitamin D-binding protein gene with compression strength index variation in Caucasian nuclear families. Osteoporos Int (2009) 0.85

The differences of femoral neck geometric parameters: effects of age, gender and race. Osteoporos Int (2009) 0.82

Cortical bone health shows significant linkage to chromosomes 2p, 3p, and 17q in 10-year-old children. Bone (2011) 0.81

Bivariate genome-wide association analyses identified genes with pleiotropic effects for femoral neck bone geometry and age at menarche. PLoS One (2013) 0.78

Association analyses of CYP19 gene polymorphisms with height variation in a large sample of Caucasian nuclear families. Hum Genet (2006) 0.77

Cross-sectional geometry of the femoral midshaft in baboons is heritable. Bone (2009) 0.77

Evaluation of the effects of vitamin D receptor and estrogen receptor 1 gene polymorphisms on bone mineral density in postmenopausal women. Clin Rheumatol (2010) 0.77

Association analyses of FGFR2 gene polymorphisms with femoral neck bone mineral density in Chinese Han population. Mol Genet Genomics (2014) 0.77

Statistical Analyses of Femur Parameters for Designing Anatomical Plates. Comput Math Methods Med (2016) 0.75

Articles cited by this

Multipoint quantitative-trait linkage analysis in general pedigrees. Am J Hum Genet (1998) 40.97

Parametric and nonparametric linkage analysis: a unified multipoint approach. Am J Hum Genet (1996) 39.80

PedCheck: a program for identification of genotype incompatibilities in linkage analysis. Am J Hum Genet (1998) 23.25

A general test of association for quantitative traits in nuclear families. Am J Hum Genet (2000) 22.45

On the allelic spectrum of human disease. Trends Genet (2001) 16.26

Genome-wide association studies: theoretical and practical concerns. Nat Rev Genet (2005) 14.30

A comparison of linkage disequilibrium measures for fine-scale mapping. Genomics (1995) 11.58

Epidemiology of osteoporosis and osteoporotic fractures. Epidemiol Rev (1985) 7.40

Estrogen resistance caused by a mutation in the estrogen-receptor gene in a man. N Engl J Med (1994) 6.59

Sex steroids and the construction and conservation of the adult skeleton. Endocr Rev (2002) 6.38

BMD at multiple sites and risk of fracture of multiple types: long-term results from the Study of Osteoporotic Fractures. J Bone Miner Res (2003) 4.64

A unitary model for involutional osteoporosis: estrogen deficiency causes both type I and type II osteoporosis in postmenopausal women and contributes to bone loss in aging men. J Bone Miner Res (1998) 4.24

Structural trends in the aging femoral neck and proximal shaft: analysis of the Third National Health and Nutrition Examination Survey dual-energy X-ray absorptiometry data. J Bone Miner Res (2000) 3.36

Genetics of osteoporosis. Endocr Rev (2002) 2.91

Circumventing multiple testing: a multilocus Monte Carlo approach to testing for association. Genet Epidemiol (2000) 2.74

Osteoporosis prevention, diagnosis, and therapy. NIH Consens Statement (2001) 2.72

Long-term fracture prediction by bone mineral assessed at different skeletal sites. J Bone Miner Res (1993) 2.59

Predicting femoral neck strength from bone mineral data. A structural approach. Invest Radiol (1990) 2.55

Structural and biomechanical basis of sexual dimorphism in femoral neck fragility has its origins in growth and aging. J Bone Miner Res (2003) 2.48

Bone strength and its determinants. Osteoporos Int (2003) 2.25

Structural adaptation to changing skeletal load in the progression toward hip fragility: the study of osteoporotic fractures. J Bone Miner Res (2001) 1.77

Clinical review 144: Estrogen and the male skeleton. J Clin Endocrinol Metab (2002) 1.61

Population admixture may appear to mask, change or reverse genetic effects of genes underlying complex traits. Genetics (2001) 1.57

Association of 5' estrogen receptor alpha gene polymorphisms with bone mineral density, vertebral bone area and fracture risk. Hum Mol Genet (2003) 1.56

Linkage of structure at the proximal femur to chromosomes 3, 7, 8, and 19. J Bone Miner Res (2003) 1.55

Estrogen receptor beta: the antimechanostat? Bone (2005) 1.54

Non-invasive measurement of long bone cross-sectional moment of inertia by photon absorptiometry. J Biomech (1984) 1.52

Molecular studies of identification of genes for osteoporosis: the 2002 update. J Endocrinol (2003) 1.48

Combination of bone mineral density and upper femur geometry improves the prediction of hip fracture. Osteoporos Int (2004) 1.32

Association of polymorphisms of the estrogen receptor alpha gene with bone mineral density and fracture risk in women: a meta-analysis. J Bone Miner Res (2002) 1.29

Femoral bone structural geometry adapts to mechanical loading and is influenced by sex steroids: the Penn State Young Women's Health Study. Bone (2004) 1.29

Measuring the structural strength of bones with dual-energy X-ray absorptiometry: principles, technical limitations, and future possibilities. Osteoporos Int (2003) 1.27

Mapping quantitative trait loci that influence femoral cross-sectional area in mice. J Bone Miner Res (2002) 1.24

Cross-sectional geometry, bone strength, and bone mass in the proximal femur in black and white postmenopausal women. J Bone Miner Res (2000) 1.21

Genome screen for quantitative trait loci underlying normal variation in femoral structure. J Bone Miner Res (2001) 1.16

Genetic case-control association studies--correcting for multiple testing. Hum Genet (2001) 1.08

The influence of an insulin-like growth factor I gene promoter polymorphism on hip bone geometry and the risk of nonvertebral fracture in the elderly: the Rotterdam Study. J Bone Miner Res (2004) 1.08

The genetics of proximal femur geometry, distribution of bone mass and bone mineral density. Osteoporos Int (1996) 1.02

Role of estrogen receptor-alpha in pharmacogenetics of estrogen action. Curr Opin Lipidol (2003) 1.00

Evaluating bias due to population stratification in case-control association studies of admixed populations. Genet Epidemiol (2004) 0.98

Effects of current and discontinued estrogen replacement therapy on hip structural geometry: the study of osteoporotic fractures. J Bone Miner Res (2001) 0.95

Association between COLIA1 Sp1 alleles and femoral neck geometry. Calcif Tissue Int (2001) 0.94

Current limitations of SNP data from the public domain for studies of complex disorders: a test for ten candidate genes for obesity and osteoporosis. BMC Genet (2004) 0.93

Femoral neck fragility in women has its structural and biomechanical basis established by periosteal modeling during growth and endocortical remodeling during aging. Osteoporos Int (2003) 0.91

Estrogen receptor genotypes and their association with the 10-year changes in bone mineral density and osteocalcin concentrations. J Clin Endocrinol Metab (2004) 0.91

Relationship of estrogen receptor genotypes to bone mineral density and to rates of bone loss in men. J Clin Endocrinol Metab (2004) 0.89

Hip axis length and osteoporotic fractures. Study of Osteoporotic Fractures Research Group. J Bone Miner Res (1995) 0.88

Codon 325 sequence polymorphism of the estrogen receptor alpha gene and bone mineral density in postmenopausal women. J Steroid Biochem Mol Biol (2001) 0.84

Association studies in psychiatric genetics: what are we doing? Mol Psychiatry (2002) 0.82

The role of estrogens in men and androgens in women. Endocrinol Metab Clin North Am (2003) 0.82

Association of a G2014A transition in exon 8 of the estrogen receptor-alpha gene with postmenopausal osteoporosis. Osteoporos Int (2001) 0.78

Association of a T262C transition in exon 1 of estrogen-receptor-alpha gene with skeletal responsiveness to estrogen in post-menopausal women. J Endocrinol Invest (2001) 0.77

Test of linkage and/or association between the estrogen receptor alpha gene with bone mineral density in Caucasian nuclear families. Bone (2004) 0.76

Proper metrics for clinical trials: transformations and other procedures to remove non-normality effects. Stat Med (2003) 0.75

Articles by these authors

Analyses and comparison of accuracy of different genotype imputation methods. PLoS One (2008) 3.41

A gene expression signature predicts survival of patients with stage I non-small cell lung cancer. PLoS Med (2006) 3.37

Genome-wide association scans identified CTNNBL1 as a novel gene for obesity. Hum Mol Genet (2008) 3.24

Relationship of obesity with osteoporosis. J Clin Endocrinol Metab (2007) 2.71

Genome-wide copy-number-variation study identified a susceptibility gene, UGT2B17, for osteoporosis. Am J Hum Genet (2008) 2.65

Correlation of obesity and osteoporosis: effect of fat mass on the determination of osteoporosis. J Bone Miner Res (2008) 2.40

Meta-analysis suggests that smoking is associated with an increased risk of early natural menopause. Menopause (2012) 2.36

Genome partitioning of genetic variation for height from 11,214 sibling pairs. Am J Hum Genet (2007) 2.27

Bivariate association analyses for the mixture of continuous and binary traits with the use of extended generalized estimating equations. Genet Epidemiol (2009) 2.19

Genome-wide association and follow-up replication studies identified ADAMTS18 and TGFBR3 as bone mass candidate genes in different ethnic groups. Am J Hum Genet (2009) 2.14

Hotelling's T2 multivariate profiling for detecting differential expression in microarrays. Bioinformatics (2005) 2.10

Comparative studies of de novo assembly tools for next-generation sequencing technologies. Bioinformatics (2011) 2.05

A genomewide linkage scan for quantitative-trait loci for obesity phenotypes. Am J Hum Genet (2002) 1.91

Mutation patterns at dinucleotide microsatellite loci in humans. Am J Hum Genet (2002) 1.71

Rare ADH variant constellations are specific for alcohol dependence. Alcohol Alcohol (2012) 1.66

MiR-138 induces cell cycle arrest by targeting cyclin D3 in hepatocellular carcinoma. Carcinogenesis (2012) 1.55

Molecular genetic studies of gene identification for osteoporosis: a 2004 update. J Bone Miner Res (2006) 1.52

Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q. Neuropsychopharmacology (2011) 1.50

Comparative studies of copy number variation detection methods for next-generation sequencing technologies. PLoS One (2013) 1.48

Molecular studies of identification of genes for osteoporosis: the 2002 update. J Endocrinol (2003) 1.48

Gene-gene interaction between RBMS3 and ZNF516 influences bone mineral density. J Bone Miner Res (2013) 1.45

SNP rs6265 regulates protein phosphorylation and osteoblast differentiation and influences BMD in humans. J Bone Miner Res (2013) 1.44

Genome-wide association study identifies ALDH7A1 as a novel susceptibility gene for osteoporosis. PLoS Genet (2010) 1.41

Genome-wide association study suggested copy number variation may be associated with body mass index in the Chinese population. J Hum Genet (2009) 1.40

A whole-genome linkage scan suggests several genomic regions potentially containing QTLs underlying the variation of stature. Am J Med Genet (2002) 1.39

Genome-wide association scan for stature in Chinese: evidence for ethnic specific loci. Hum Genet (2008) 1.39

Wnt/β-catenin signaling activates bone morphogenetic protein 2 expression in osteoblasts. Bone (2012) 1.38

Bayesian mapping of quantitative trait loci for multiple complex traits with the use of variance components. Am J Hum Genet (2007) 1.35

A whole-genome linkage scan suggests several genomic regions potentially containing quantitative trait Loci for osteoporosis. J Clin Endocrinol Metab (2002) 1.33

Meta-analysis of genome-wide linkage studies in BMI and obesity. Obesity (Silver Spring) (2007) 1.32

Comprehensive association analysis of nine candidate genes with serum 25-hydroxy vitamin D levels among healthy Caucasian subjects. Hum Genet (2010) 1.31

SNPP: automating large-scale SNP genotype data management. Bioinformatics (2004) 1.31

A novel pathophysiological mechanism for osteoporosis suggested by an in vivo gene expression study of circulating monocytes. J Biol Chem (2005) 1.30

Genome-wide association and replication studies identified TRHR as an important gene for lean body mass. Am J Hum Genet (2009) 1.28

Powerful bivariate genome-wide association analyses suggest the SOX6 gene influencing both obesity and osteoporosis phenotypes in males. PLoS One (2009) 1.26

Robust and comprehensive analysis of 20 osteoporosis candidate genes by very high-density single-nucleotide polymorphism screen among 405 white nuclear families identified significant association and gene-gene interaction. J Bone Miner Res (2006) 1.24

Genome-wide association study of exercise behavior in Dutch and American adults. Med Sci Sports Exerc (2009) 1.22

Genome-wide association analyses identify SPOCK as a key novel gene underlying age at menarche. PLoS Genet (2009) 1.21

Identification of PLCL1 gene for hip bone size variation in females in a genome-wide association study. PLoS One (2008) 1.21

A new permutation strategy of pathway-based approach for genome-wide association study. BMC Bioinformatics (2009) 1.19

On genome-wide association studies and their meta-analyses: lessons learned from osteoporosis studies. J Clin Endocrinol Metab (2013) 1.18

Is replication the gold standard for validating genome-wide association findings? PLoS One (2008) 1.18

Multistage genome-wide association meta-analyses identified two new loci for bone mineral density. Hum Mol Genet (2013) 1.17

Genome-wide scan identified QTLs underlying femoral neck cross-sectional geometry that are novel studied risk factors of osteoporosis. J Bone Miner Res (2005) 1.16

Genomewide linkage scan for quantitative trait loci underlying variation in age at menarche. J Clin Endocrinol Metab (2006) 1.16

Pathway-based genome-wide association analysis identified the importance of regulation-of-autophagy pathway for ultradistal radius BMD. J Bone Miner Res (2010) 1.15

Analyses and comparison of imputation-based association methods. PLoS One (2010) 1.12

Genome-wide association study identified UQCC locus for spine bone size in humans. Bone (2012) 1.12

Group sparse canonical correlation analysis for genomic data integration. BMC Bioinformatics (2013) 1.12

Comparison of population-based association study methods correcting for population stratification. PLoS One (2008) 1.11

Biological pathway-based genome-wide association analysis identified the vasoactive intestinal peptide (VIP) pathway important for obesity. Obesity (Silver Spring) (2010) 1.10

Univariate/multivariate genome-wide association scans using data from families and unrelated samples. PLoS One (2009) 1.10

Genetic linkage of human height is confirmed to 9q22 and Xq24. Hum Genet (2006) 1.10

Role of genetics in osteoporosis. Endocrine (2002) 1.10

ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample. Am J Med Genet B Neuropsychiatr Genet (2013) 1.08

Incorporating single-locus tests into haplotype cladistic analysis in case-control studies. PLoS Genet (2007) 1.08

Genomic regions identified for BMD in a large sample including epistatic interactions and gender-specific effects. J Bone Miner Res (2006) 1.08

Genetic determination and correlation of body mass index and bone mineral density at the spine and hip in Chinese Han ethnicity. Osteoporos Int (2005) 1.08

An in vivo genome wide gene expression study of circulating monocytes suggested GBP1, STAT1 and CXCL10 as novel risk genes for the differentiation of peak bone mass. Bone (2008) 1.08

Gene selection for classification of microarray data based on the Bayes error. BMC Bioinformatics (2007) 1.07

Whole genome distribution and ethnic differentiation of copy number variation in Caucasian and Asian populations. PLoS One (2009) 1.06

Searching for osteoporosis genes in the post-genome era: progress and challenges. Osteoporos Int (2003) 1.05

Genome-wide association study identifies two novel loci containing FLNB and SBF2 genes underlying stature variation. Hum Mol Genet (2008) 1.03

Receiver-operating characteristic analyses of body mass index, waist circumference and waist-to-hip ratio for obesity: Screening in young adults in central south of China. Clin Nutr (2006) 1.02

Efficient utilization of rare variants for detection of disease-related genomic regions. PLoS One (2010) 1.02

The imprinted gene neuronatin is regulated by metabolic status and associated with obesity. Obesity (Silver Spring) (2009) 1.02

Polymorphisms of estrogen-biosynthesis genes CYP17 and CYP19 may influence age at menarche: a genetic association study in Caucasian females. Hum Mol Genet (2006) 1.01

Tests of association for quantitative traits in nuclear families using principal components to correct for population stratification. Ann Hum Genet (2009) 1.01

Runs of homozygosity identify a recessive locus 12q21.31 for human adult height. J Clin Endocrinol Metab (2010) 1.00

Polymorphisms in predicted miRNA binding sites and osteoporosis. J Bone Miner Res (2011) 1.00

In vivo genome-wide expression study on human circulating B cells suggests a novel ESR1 and MAPK3 network for postmenopausal osteoporosis. J Bone Miner Res (2008) 1.00

Genetic dissection of human stature in a large sample of multiplex pedigrees. Ann Hum Genet (2004) 1.00

Molecular genetic studies of gene identification for osteoporosis: the 2009 update. Endocr Rev (2010) 1.00

Peripheral blood monocyte-expressed ANXA2 gene is involved in pathogenesis of osteoporosis in humans. Mol Cell Proteomics (2011) 0.99

Critical assessment of coalescent simulators in modeling recombination hotspots in genomic sequences. BMC Bioinformatics (2014) 0.99

Transcriptional regulation of BMP2 expression by the PTH-CREB signaling pathway in osteoblasts. PLoS One (2011) 0.98

Polymorphism in the insulin-like growth factor 1 gene is associated with age at menarche in caucasian females. Hum Reprod (2007) 0.98

Genome-wide association study of copy number variation identified gremlin1 as a candidate gene for lean body mass. J Hum Genet (2011) 0.97