Published in Nat Rev Genet on July 31, 2012
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Measuring adolescents' exposure to victimization: The Environmental Risk (E-Risk) Longitudinal Twin Study. Dev Psychopathol (2015) 0.86
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Genome-wide methylation study on depression: differential methylation and variable methylation in monozygotic twins. Transl Psychiatry (2015) 0.82
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The Origins of Cognitive Deficits in Victimized Children: Implications for Neuroscientists and Clinicians. Am J Psychiatry (2016) 0.77
Plasma protein biomarkers of Alzheimer's disease endophenotypes in asymptomatic older twins: early cognitive decline and regional brain volumes. Transl Psychiatry (2015) 0.77
A meta-analysis of heritability of cognitive aging: minding the "missing heritability" gap. Neuropsychol Rev (2015) 0.76
Genetic and environmental influence on DNA strand break repair: a twin study. Environ Mol Mutagen (2013) 0.76
Cross-Disorder Genetic Analysis of Tic Disorders, Obsessive-Compulsive, and Hoarding Symptoms. Front Psychiatry (2016) 0.76
Use of an electronic medical record to create the marshfield clinic twin/multiple birth cohort. Genet Epidemiol (2014) 0.76
Effects of Light-Emitting Diode Therapy on Muscle Hypertrophy, Gene Expression, Performance, Damage, and Delayed-Onset Muscle Soreness: Case-control Study with a Pair of Identical Twins. Am J Phys Med Rehabil (2016) 0.76
Longitudinal weight differences, gene expression and blood biomarkers in BMI-discordant identical twins. Int J Obes (Lond) (2015) 0.75
Utilizing twins as controls for non-twin case-materials in genome wide association studies. PLoS One (2013) 0.75
Danish cohort of monozygotic inflammatory bowel disease twins: Clinical characteristics and inflammatory activity. World J Gastroenterol (2016) 0.75
Serum complement C3f and fibrinopeptide A are potential novel diagnostic biomarkers for non-alcoholic fatty liver disease: a study in Qingdao Twins. PLoS One (2014) 0.75
Anxiety trajectories in the second half of life: Genetic and environmental contributions over age. Psychol Aging (2016) 0.75
Differences in frontal and limbic brain activation in a small sample of monozygotic twin pairs discordant for severe stressful life events. Neurobiol Stress (2016) 0.75
Limited common origins of multiple adult health-related behaviors: Evidence from U.S. twins. Soc Sci Med (2016) 0.75
Heritability of Lower Urinary Tract Symptoms in Men: A Twin Study. J Urol (2016) 0.75
Using information of relatives in genomic prediction to apply effective stratified medicine. Sci Rep (2017) 0.75
The association between lower educational attainment and depression owing to shared genetic effects? Results in ~25,000 subjects. Mol Psychiatry (2015) 0.75
Epigenetic Modifications of Major Depressive Disorder. Int J Mol Sci (2016) 0.75
Parental Reports of Infant and Child Eating Behaviors are not Affected by Their Beliefs About Their Twins' Zygosity. Behav Genet (2016) 0.75
Genetics of Tinnitus: Time to Biobank Phantom Sounds. Front Genet (2017) 0.75
Common SNPs explain a large proportion of the heritability for human height. Nat Genet (2010) 35.02
Environmental and heritable factors in the causation of cancer--analyses of cohorts of twins from Sweden, Denmark, and Finland. N Engl J Med (2000) 25.49
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MicroRNA biogenesis: coordinated cropping and dicing. Nat Rev Mol Cell Biol (2005) 18.94
Epigenetic differences arise during the lifetime of monozygotic twins. Proc Natl Acad Sci U S A (2005) 15.46
Heritability in the genomics era--concepts and misconceptions. Nat Rev Genet (2008) 13.42
Five years of GWAS discovery. Am J Hum Genet (2012) 12.97
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Characterizing the quantitative genetic contribution to rheumatoid arthritis using data from twins. Arthritis Rheum (2000) 6.88
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Gene-environment interactions in psychiatry: joining forces with neuroscience. Nat Rev Neurosci (2006) 5.25
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Unravelling the effects of the environment and host genotype on the gut microbiome. Nat Rev Microbiol (2011) 4.57
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A meta-analysis of estimated genetic and environmental effects on smoking behavior in male and female adult twins. Addiction (2003) 4.37
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Genome, epigenome and RNA sequences of monozygotic twins discordant for multiple sclerosis. Nature (2010) 3.90
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Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus. Genome Res (2009) 3.81
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A population-based twin study of lifetime major depression in men and women. Arch Gen Psychiatry (1999) 3.29
Genetic influences on human brain structure: a review of brain imaging studies in twins. Hum Brain Mapp (2007) 3.15
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Heritable rather than age-related environmental and stochastic factors dominate variation in DNA methylation of the human IGF2/H19 locus. Hum Mol Genet (2007) 3.06
Telomere length predicts survival independent of genetic influences. Aging Cell (2007) 3.01
Disease-associated epigenetic changes in monozygotic twins discordant for schizophrenia and bipolar disorder. Hum Mol Genet (2011) 2.99
Sex differences in heritability of BMI: a comparative study of results from twin studies in eight countries. Twin Res (2003) 2.96
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Risk factors for osteoarthritis: genetics. Osteoarthritis Cartilage (2004) 2.74
The heritability of general cognitive ability increases linearly from childhood to young adulthood. Mol Psychiatry (2009) 2.52
Twin study indicates loss of interaction between microbiota and mucosa of patients with ulcerative colitis. Gastroenterology (2011) 2.52
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A twin approach to unraveling epigenetics. Trends Genet (2011) 2.38
Acquired obesity is associated with changes in the serum lipidomic profile independent of genetic effects--a monozygotic twin study. PLoS One (2007) 2.38
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DNA methylation analysis of multiple tissues from newborn twins reveals both genetic and intrauterine components to variation in the human neonatal epigenome. Hum Mol Genet (2010) 2.33
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A note on the statistical power in extended twin designs. Behav Genet (2000) 2.05
Characteristics and concordance of autism spectrum disorders among 277 twin pairs. Arch Pediatr Adolesc Med (2009) 1.99
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Global transcript profiles of fat in monozygotic twins discordant for BMI: pathways behind acquired obesity. PLoS Med (2008) 1.94
Identification of genes modulated in rheumatoid arthritis using complementary DNA microarray analysis of lymphoblastoid B cell lines from disease-discordant monozygotic twins. Arthritis Rheum (2006) 1.92
Association of lipidome remodeling in the adipocyte membrane with acquired obesity in humans. PLoS Biol (2011) 1.89
A genome-wide metabolic QTL analysis in Europeans implicates two loci shaped by recent positive selection. PLoS Genet (2011) 1.83
Genetic contribution to variation in cognitive function: an FMRI study in twins. Science (2009) 1.81
How heritable is Alzheimer's disease late in life? Findings from Swedish twins. Ann Neurol (2004) 1.77
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Postmenopausal hormone replacement therapy modifies skeletal muscle composition and function: a study with monozygotic twin pairs. J Appl Physiol (1985) (2009) 1.74
Aberrant DNA methylation associated with bipolar disorder identified from discordant monozygotic twins. Mol Psychiatry (2007) 1.74
Genetic influences on exercise participation in 37,051 twin pairs from seven countries. PLoS One (2006) 1.71
A genome-wide scan for naevus count: linkage to CDKN2A and to other chromosome regions. Eur J Hum Genet (2006) 1.70
Autism spectrum disorders and autistic like traits: similar etiology in the extreme end and the normal variation. Arch Gen Psychiatry (2012) 1.66
Increased DNA methylation at the AXIN1 gene in a monozygotic twin from a pair discordant for a caudal duplication anomaly. Am J Hum Genet (2006) 1.66
Twin and family studies of the human electroencephalogram: a review and a meta-analysis. Biol Psychol (2002) 1.66
GenomEUtwin: a strategy to identify genetic influences on health and disease. Twin Res (2003) 1.63
Human metabolic profiles are stably controlled by genetic and environmental variation. Mol Syst Biol (2011) 1.60
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Identification of unique microRNA signature associated with lupus nephritis. PLoS One (2010) 1.53
Metabolic fingerprinting as a diagnostic tool. Pharmacogenomics (2007) 1.51
Physical activity reduces the influence of genetic effects on BMI and waist circumference: a study in young adult twins. Int J Obes (Lond) (2008) 1.51
Epigenetic differences in cortical neurons from a pair of monozygotic twins discordant for Alzheimer's disease. PLoS One (2009) 1.49
Investigation of post-transcriptional gene regulatory networks associated with autism spectrum disorders by microRNA expression profiling of lymphoblastoid cell lines. Genome Med (2010) 1.41
DNA methylation and gene expression changes in monozygotic twins discordant for psoriasis: identification of epigenetically dysregulated genes. PLoS Genet (2012) 1.35
Dietary patterns and heritability of food choice in a UK female twin cohort. Twin Res Hum Genet (2007) 1.29
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Influence of genes and environment on brain volumes in twin pairs concordant and discordant for bipolar disorder. Arch Gen Psychiatry (2009) 1.22
Expression profiling in monozygotic twins discordant for bipolar disorder reveals dysregulation of the WNT signalling pathway. Mol Psychiatry (2007) 1.21
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Common SNPs explain a large proportion of the heritability for human height. Nat Genet (2010) 35.02
Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89
Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs. Hum Mol Genet (2006) 13.16
Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. Nat Genet (2008) 12.32
Variants in MTNR1B influence fasting glucose levels. Nat Genet (2008) 10.85
A versatile gene-based test for genome-wide association studies. Am J Hum Genet (2010) 8.44
Persistent epigenetic differences associated with prenatal exposure to famine in humans. Proc Natl Acad Sci U S A (2008) 8.39
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Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet (2013) 8.02
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet (2010) 7.94
Novel genes identified in a high-density genome wide association study for nicotine dependence. Hum Mol Genet (2006) 7.90
Assumption-free estimation of heritability from genome-wide identity-by-descent sharing between full siblings. PLoS Genet (2006) 7.13
Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. Nat Genet (2010) 6.49
Heritability of adult body height: a comparative study of twin cohorts in eight countries. Twin Res (2003) 6.43
A mega-analysis of genome-wide association studies for major depressive disorder. Mol Psychiatry (2012) 6.34
DNA methylation profiles in monozygotic and dizygotic twins. Nat Genet (2009) 5.99
Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits. Nat Genet (2012) 5.55
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Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nat Genet (2012) 5.48
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Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nat Genet (2012) 4.73
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science (2013) 4.71
A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation. PLoS Genet (2008) 4.57
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Nat Genet (2012) 4.37
DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific. Hum Mol Genet (2009) 4.25
Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways. Diabetes (2010) 4.07
Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD. PLoS Genet (2010) 3.91
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Identification of seven loci affecting mean telomere length and their association with disease. Nat Genet (2013) 3.87
Bias, precision and heritability of self-reported and clinically measured height in Australian twins. Hum Genet (2006) 3.84
Genome-wide association studies identify four ER negative-specific breast cancer risk loci. Nat Genet (2013) 3.81
Common sequence variants on 20q11.22 confer melanoma susceptibility. Nat Genet (2008) 3.79
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Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels. Circulation (2011) 3.68
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Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study. Lancet (2012) 3.48
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet (2011) 3.40
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nat Genet (2010) 3.37
A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor-negative breast cancer. Nat Genet (2011) 3.37
Defining nicotine dependence for genetic research: evidence from Australian twins. Psychol Med (2004) 3.26
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet (2013) 3.25
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet (2012) 3.21
Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. Nat Genet (2011) 3.18
Common variants in the trichohyalin gene are associated with straight hair in Europeans. Am J Hum Genet (2009) 3.18
Genetic influences on human brain structure: a review of brain imaging studies in twins. Hum Brain Mapp (2007) 3.15
New gene functions in megakaryopoiesis and platelet formation. Nature (2011) 3.14
Heritable rather than age-related environmental and stochastic factors dominate variation in DNA methylation of the human IGF2/H19 locus. Hum Mol Genet (2007) 3.06
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. Nat Genet (2012) 3.04
Identification of IL6R and chromosome 11q13.5 as risk loci for asthma. Lancet (2011) 3.03
Geographical structure and differential natural selection among North European populations. Genome Res (2009) 3.03
Telomere length predicts survival independent of genetic influences. Aging Cell (2007) 3.01
A single SNP in an evolutionary conserved region within intron 86 of the HERC2 gene determines human blue-brown eye color. Am J Hum Genet (2008) 3.00
A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma. Nature (2011) 2.96
Sex differences in heritability of BMI: a comparative study of results from twin studies in eight countries. Twin Res (2003) 2.96
Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet (2013) 2.92
Anesthesia and cognitive performance in children: no evidence for a causal relationship. Twin Res Hum Genet (2009) 2.90
Evidence of genetic enrichment for exceptional survival using a family approach: the Leiden Longevity Study. Eur J Hum Genet (2006) 2.89
A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications. Biol Psychiatry (2011) 2.87
Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. PLoS Genet (2013) 2.83
Variation in the human TP53 gene affects old age survival and cancer mortality. Exp Gerontol (2005) 2.81
Seventy-five genetic loci influencing the human red blood cell. Nature (2012) 2.77
FTO genotype is associated with phenotypic variability of body mass index. Nature (2012) 2.77
Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma. Nat Genet (2010) 2.75
Variation, patterns, and temporal stability of DNA methylation: considerations for epigenetic epidemiology. FASEB J (2010) 2.74
Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder. Am J Hum Genet (2011) 2.71
Genome-wide association study identifies variants at 9p21 and 22q13 associated with development of cutaneous nevi. Nat Genet (2009) 2.65
A genome-wide association meta-analysis identifies new childhood obesity loci. Nat Genet (2012) 2.60
Multiple common susceptibility variants near BMP pathway loci GREM1, BMP4, and BMP2 explain part of the missing heritability of colorectal cancer. PLoS Genet (2011) 2.47
Large-scale analysis of association between GDF5 and FRZB variants and osteoarthritis of the hip, knee, and hand. Arthritis Rheum (2009) 2.47
A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11. Hum Mol Genet (2012) 2.45