Published in Mol Biol Cell on June 01, 2002
Rab10 regulates membrane transport through early endosomes of polarized Madin-Darby canine kidney cells. Mol Biol Cell (2006) 1.92
The interaction of JRAB/MICAL-L2 with Rab8 and Rab13 coordinates the assembly of tight junctions and adherens junctions. Mol Biol Cell (2007) 1.49
Rab13 regulates membrane trafficking between TGN and recycling endosomes in polarized epithelial cells. J Cell Biol (2008) 1.30
Rab13 regulates PKA signaling during tight junction assembly. J Cell Biol (2004) 1.24
Cingulin regulates claudin-2 expression and cell proliferation through the small GTPase RhoA. Mol Biol Cell (2006) 1.22
JRAB/MICAL-L2 is a junctional Rab13-binding protein mediating the endocytic recycling of occludin. Mol Biol Cell (2006) 1.20
Rab3D regulates a novel vesicular trafficking pathway that is required for osteoclastic bone resorption. Mol Cell Biol (2005) 1.08
Transport to late endosomes is required for efficient reovirus infection. J Virol (2012) 1.03
Rab8 regulates the actin-based movement of melanosomes. Mol Biol Cell (2005) 1.03
Regulation of tight junction assembly and epithelial polarity by a resident protein of apical endosomes. Traffic (2010) 1.02
Involvement of actinin-4 in the recruitment of JRAB/MICAL-L2 to cell-cell junctions and the formation of functional tight junctions. Mol Cell Biol (2008) 0.97
Rab13-dependent trafficking of RhoA is required for directional migration and angiogenesis. J Biol Chem (2011) 0.92
Endocytosis and recycling of tight junction proteins in inflammation. J Biomed Biotechnol (2010) 0.86
MICAL-like1 mediates epidermal growth factor receptor endocytosis. Mol Biol Cell (2011) 0.85
Membrane trafficking in podocyte health and disease. Pediatr Nephrol (2012) 0.84
Rab13 small G protein and junctional Rab13-binding protein (JRAB) orchestrate actin cytoskeletal organization during epithelial junctional development. J Biol Chem (2012) 0.83
Rab13 is upregulated during osteoclast differentiation and associates with small vesicles revealing polarized distribution in resorbing cells. J Histochem Cytochem (2012) 0.81
Release of Infectious Hepatitis C Virus from Huh7 Cells Occurs via a trans-Golgi Network-to-Endosome Pathway Independent of Very-Low-Density Lipoprotein Secretion. J Virol (2016) 0.80
Evidence for defective Rab GTPase-dependent cargo traffic in immune disorders. Exp Cell Res (2013) 0.80
Rab14 regulation of claudin-2 trafficking modulates epithelial permeability and lumen morphogenesis. Mol Biol Cell (2014) 0.80
Scaffolding protein GOPC regulates tight junction structure. Cell Tissue Res (2015) 0.79
Membrane traffic as a coordinator of cell migration and junction remodeling. Commun Integr Biol (2011) 0.79
Bladder filling and voiding affect umbrella cell tight junction organization and function. Am J Physiol Renal Physiol (2013) 0.79
Analysis of occludin trafficking, demonstrating continuous endocytosis, degradation, recycling and biosynthetic secretory trafficking. PLoS One (2014) 0.78
Cellular mechanism of bile acid-accelerated hepatocyte polarity. Small GTPases (2011) 0.78
PKCι interacts with Rab14 and modulates epithelial barrier function through regulation of claudin-2 levels. Mol Biol Cell (2015) 0.78
Traffic jams and the complex role of α-Synuclein aggregation in Parkinson disease. Small GTPases (2016) 0.77
A complex of Rab13 with MICAL-L2 and α-actinin-4 is essential for insulin-dependent GLUT4 exocytosis. Mol Biol Cell (2015) 0.77
Rab13 Traffics on Vesicles Independent of Prenylation. J Biol Chem (2016) 0.76
Vesicular Trafficking Defects, Developmental Abnormalities, and Alterations in the Cellular Death Process Occur in Cell Lines that Over-Express Dictyostelium GTPase, Rab2, and Rab2 Mutants. Biology (Basel) (2014) 0.75
Conformational plasticity of JRAB/MICAL-L2 provides "law and order" in collective cell migration. Mol Biol Cell (2016) 0.75
Novel interaction of Rab13 and Rab8 with endospanins. FEBS Open Bio (2013) 0.75
Molecular characterization of human osteoblast-derived extracellular vesicle mRNA using next-generation sequencing. Biochim Biophys Acta (2017) 0.75
Non-canonical functions of claudin proteins: Beyond the regulation of cell-cell adhesions. Tissue Barriers (2017) 0.75
Rab GTPases in Immunity and Inflammation. Front Cell Infect Microbiol (2017) 0.75
Rab proteins as membrane organizers. Nat Rev Mol Cell Biol (2001) 19.95
Occludin: a novel integral membrane protein localizing at tight junctions. J Cell Biol (1993) 10.65
The small GTPase rab5 functions as a regulatory factor in the early endocytic pathway. Cell (1992) 10.53
Claudin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin. J Cell Biol (1998) 7.78
The role of the cell adhesion molecule uvomorulin in the formation and maintenance of the epithelial junctional complex. J Cell Biol (1988) 6.27
Paracellin-1, a renal tight junction protein required for paracellular Mg2+ resorption. Science (1999) 6.04
Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins. J Cell Biol (1999) 5.06
Sec6/8 complex is recruited to cell-cell contacts and specifies transport vesicle delivery to the basal-lateral membrane in epithelial cells. Cell (1998) 4.80
Rab5 regulates motility of early endosomes on microtubules. Nat Cell Biol (1999) 4.74
A single gene product, claudin-1 or -2, reconstitutes tight junction strands and recruits occludin in fibroblasts. J Cell Biol (1998) 4.64
Apical membrane aminopeptidase appears at site of cell-cell contact in cultured kidney epithelial cells. Proc Natl Acad Sci U S A (1980) 4.63
Rabaptin-5 is a direct effector of the small GTPase Rab5 in endocytic membrane fusion. Cell (1995) 4.39
Interaction of a Golgi-associated kinesin-like protein with Rab6. Science (1998) 4.25
A synthetic peptide corresponding to the extracellular domain of occludin perturbs the tight junction permeability barrier. J Cell Biol (1997) 3.86
Occludin-deficient embryonic stem cells can differentiate into polarized epithelial cells bearing tight junctions. J Cell Biol (1998) 3.62
The role of ARF and Rab GTPases in membrane transport. Curr Opin Cell Biol (1999) 3.42
CNS myelin and sertoli cell tight junction strands are absent in Osp/claudin-11 null mice. Cell (1999) 3.39
Rab8, a small GTPase involved in vesicular traffic between the TGN and the basolateral plasma membrane. J Cell Biol (1993) 3.29
Occludin and claudins in tight-junction strands: leading or supporting players? Trends Cell Biol (1999) 3.23
Morphological factors influencing transepithelial permeability: a model for the resistance of the zonula occludens. J Membr Biol (1978) 3.02
Rab6 coordinates a novel Golgi to ER retrograde transport pathway in live cells. J Cell Biol (1999) 2.85
Regulation of the movement of solutes across tight junctions. Annu Rev Physiol (1998) 2.79
Sec6/8 complexes on trans-Golgi network and plasma membrane regulate late stages of exocytosis in mammalian cells. J Cell Biol (2001) 2.69
Protein interactions at the tight junction. Actin has multiple binding partners, and ZO-1 forms independent complexes with ZO-2 and ZO-3. J Biol Chem (1999) 2.68
Pores in the wall: claudins constitute tight junction strands containing aqueous pores. J Cell Biol (2000) 2.62
Heterogeneity in expression and subcellular localization of claudins 2, 3, 4, and 5 in the rat liver, pancreas, and gut. Gastroenterology (2001) 2.62
Assembly of the tight junction: the role of diacylglycerol. J Cell Biol (1993) 2.61
Rab8 promotes polarized membrane transport through reorganization of actin and microtubules in fibroblasts. J Cell Biol (1996) 2.57
Tight junctions are membrane microdomains. J Cell Sci (2000) 2.55
The tight junction protein ZO-1 and an interacting transcription factor regulate ErbB-2 expression. EMBO J (2000) 2.44
Catenins and zonula occludens-1 form a complex during early stages in the assembly of tight junctions. J Cell Biol (1996) 2.37
Rab GTPases, directors of vesicle docking. J Biol Chem (1998) 1.96
ZO-1 mRNA and protein expression during tight junction assembly in Caco-2 cells. J Cell Biol (1989) 1.92
A small rab GTPase is distributed in cytoplasmic vesicles in non polarized cells but colocalizes with the tight junction marker ZO-1 in polarized epithelial cells. J Cell Biol (1994) 1.80
Cingulin contains globular and coiled-coil domains and interacts with ZO-1, ZO-2, ZO-3, and myosin. J Cell Biol (1999) 1.59
Inducible expression of claudin-1-myc but not occludin-VSV-G results in aberrant tight junction strand formation in MDCK cells. J Cell Sci (2000) 1.58
Expression and polarized targeting of a rab3 isoform in epithelial cells. J Cell Biol (1994) 1.50
Tight junction, a platform for trafficking and signaling protein complexes. J Cell Biol (2000) 1.41
SDS-digested freeze-fracture replica labeling electron microscopy to study the two-dimensional distribution of integral membrane proteins and phospholipids in biomembranes: practical procedure, interpretation and application. Histochem Cell Biol (1997) 1.40
In its active form, the GTP-binding protein rab8 interacts with a stress-activated protein kinase. Proc Natl Acad Sci U S A (1996) 1.33
Inhibiting cadherin function by dominant mutant E-cadherin expression increases the extent of tight junction assembly. J Cell Sci (2000) 1.17
Physical and functional interaction of rabphilin-3A with alpha-actinin. J Biol Chem (1996) 1.14
Differentiation of the epithelial apical junctional complex during mouse preimplantation development: a role for rab13 in the early maturation of the tight junction. Mech Dev (2000) 0.98
Sodium dodecyl sulfate-freeze-fracture immunolabeling of gap junctions. Methods Mol Biol (2001) 0.83
Tissue-specific and inducible Cre-mediated recombination in the gut epithelium. Genesis (2004) 6.83
Notch signals control the fate of immature progenitor cells in the intestine. Nature (2005) 6.13
Wnt/beta-catenin is essential for intestinal homeostasis and maintenance of intestinal stem cells. Mol Cell Biol (2007) 3.06
Phosphoinositide binding and phosphorylation act sequentially in the activation mechanism of ezrin. J Cell Biol (2004) 3.03
Actin, microtubules, and vimentin intermediate filaments cooperate for elongation of invadopodia. J Cell Biol (2010) 2.62
Notch and Wnt signals cooperatively control cell proliferation and tumorigenesis in the intestine. Proc Natl Acad Sci U S A (2009) 2.34
Fascin, a novel target of beta-catenin-TCF signaling, is expressed at the invasive front of human colon cancer. Cancer Res (2007) 2.26
APC and oncogenic KRAS are synergistic in enhancing Wnt signaling in intestinal tumor formation and progression. Gastroenterology (2006) 2.25
The co-workers of actin filaments: from cell structures to signals. Nat Rev Mol Cell Biol (2004) 2.01
ERM proteins in epithelial cell organization and functions. Biochim Biophys Acta (2006) 1.80
The membrane cytoskeletal crosslinker ezrin is required for metastasis of breast carcinoma cells. Breast Cancer Res (2005) 1.76
Molecular analysis of microscopic ezrin dynamics by two-photon FRAP. Proc Natl Acad Sci U S A (2002) 1.73
Disruption of Gja8 (alpha8 connexin) in mice leads to microphthalmia associated with retardation of lens growth and lens fiber maturation. Development (2002) 1.72
Chronic hemodynamic overload of the atria is an important factor for gap junction remodeling in human and rat hearts. Cardiovasc Res (2006) 1.71
Ezrin regulates E-cadherin-dependent adherens junction assembly through Rac1 activation. Mol Biol Cell (2003) 1.67
ERM proteins and NF2 tumor suppressor: the Yin and Yang of cortical actin organization and cell growth signaling. Curr Opin Cell Biol (2002) 1.61
Targeted expression of oncogenic K-ras in intestinal epithelium causes spontaneous tumorigenesis in mice. Gastroenterology (2002) 1.57
Different microtubule motors move early and late endocytic compartments. Traffic (2008) 1.50
The yeast zinc finger regulators Pdr1p and Pdr3p control pleiotropic drug resistance (PDR) as homo- and heterodimers in vivo. Mol Microbiol (2002) 1.49
Selective modification of alternative splicing by indole derivatives that target serine-arginine-rich protein splicing factors. Proc Natl Acad Sci U S A (2005) 1.45
Laparoscopy in ureteral engineering: a feasibility study. Eur Urol (2008) 1.42
Aminopeptidase-N/CD13 (EC 3.4.11.2) inhibitors: chemistry, biological evaluations, and therapeutic prospects. Med Res Rev (2006) 1.41
Lens connexins alpha3Cx46 and alpha8Cx50 interact with zonula occludens protein-1 (ZO-1). Mol Biol Cell (2003) 1.39
Notch lineages and activity in intestinal stem cells determined by a new set of knock-in mice. PLoS One (2011) 1.24
Rab13 regulates PKA signaling during tight junction assembly. J Cell Biol (2004) 1.24
Tight junction: a co-ordinator of cell signalling and membrane trafficking. Biol Cell (2005) 1.17
Myosin 1b promotes the formation of post-Golgi carriers by regulating actin assembly and membrane remodelling at the trans-Golgi network. Nat Cell Biol (2011) 1.16
Myosin Ib modulates the morphology and the protein transport within multi-vesicular sorting endosomes. J Cell Sci (2005) 1.13
Interaction of ezrin with the novel guanine nucleotide exchange factor PLEKHG6 promotes RhoG-dependent apical cytoskeleton rearrangements in epithelial cells. Mol Biol Cell (2007) 1.12
Free Brick1 is a trimeric precursor in the assembly of a functional wave complex. PLoS One (2008) 1.09
Persistent, noncytolytic infection of neurons by Borna disease virus interferes with ERK 1/2 signaling and abrogates BDNF-induced synaptogenesis. FASEB J (2004) 1.07
Plastin 1 binds to keratin and is required for terminal web assembly in the intestinal epithelium. Mol Biol Cell (2009) 1.06
Ectopic expression of syntaxin 1 in the ER redirects TI-VAMP- and cellubrevin-containing vesicles. J Cell Sci (2003) 1.03
Rab8 regulates the actin-based movement of melanosomes. Mol Biol Cell (2005) 1.03
Electron microscopic evidence for nucleation and growth of 3D acetylcholine receptor microcrystals in structured lipid-detergent matrices. Proc Natl Acad Sci U S A (2003) 1.03
Notch signaling in intestinal homeostasis across species: the cases of Drosophila, Zebrafish and the mouse. Exp Cell Res (2011) 1.03
Identification of Ank(G107), a muscle-specific ankyrin-G isoform. J Biol Chem (2002) 1.03
Co-operative effect of c-Src and ezrin in deregulation of cell-cell contacts and scattering of mammary carcinoma cells. J Cell Biochem (2004) 1.03
Villin enhances hepatocyte growth factor-induced actin cytoskeleton remodeling in epithelial cells. Mol Biol Cell (2003) 1.02
The ERM proteins interact with the HOPS complex to regulate the maturation of endosomes. Mol Biol Cell (2010) 1.02
Spatial recruitment and activation of the Fes kinase by ezrin promotes HGF-induced cell scattering. EMBO J (2007) 1.01
A new role for the architecture of microvillar actin bundles in apical retention of membrane proteins. Mol Biol Cell (2011) 1.00
Absence of alpha3 (Cx46) and alpha8 (Cx50) connexins leads to cataracts by affecting lens inner fiber cells. Exp Eye Res (2006) 1.00
Ankyrin-G in skeletal muscle: tissue-specific alternative splicing contributes to the complexity of the sarcolemmal cytoskeleton. Exp Cell Res (2005) 0.99
Enterocyte loss of polarity and gut wound healing rely upon the F-actin-severing function of villin. Proc Natl Acad Sci U S A (2013) 0.99
Mutant products of the NF2 tumor suppressor gene are degraded by the ubiquitin-proteasome pathway. J Biol Chem (2002) 0.98
Agrin elicits membrane lipid condensation at sites of acetylcholine receptor clusters in C2C12 myotubes. J Lipid Res (2006) 0.97
Mouse models of K-ras-initiated carcinogenesis. Biochim Biophys Acta (2005) 0.96
The epithelial cell cytoskeleton and intracellular trafficking. III. How is villin involved in the actin cytoskeleton dynamics in intestinal cells? Am J Physiol Gastrointest Liver Physiol (2002) 0.96
Structural and immunocytochemical alterations in eye lens fiber cells from Cx46 and Cx50 knockout mice. Eur J Cell Biol (2006) 0.94
Shigella flexneri infection is dependent on villin in the mouse intestine and in primary cultures of intestinal epithelial cells. Cell Microbiol (2005) 0.93
Ezrin regulates microvillus morphogenesis by promoting distinct activities of Eps8 proteins. Mol Biol Cell (2012) 0.93
Inhibition of pyrimidine biosynthesis pathway suppresses viral growth through innate immunity. PLoS Pathog (2013) 0.93
Cytoskeleton networks in basement membrane transmigration. Eur J Cell Biol (2010) 0.92
Enhanced sensitivity to irinotecan by Cdk1 inhibition in the p53-deficient HT29 human colon cancer cell line. Oncogene (2004) 0.91
Do cancer cells have distinct adhesions in 3D collagen matrices and in vivo? Eur J Cell Biol (2012) 0.90
Synthesis and biological study of a new series of 4'-demethylepipodophyllotoxin derivatives. J Med Chem (2005) 0.89
Villin severing activity enhances actin-based motility in vivo. Mol Biol Cell (2006) 0.89
Aminopeptidase-N/CD13 is a potential proapoptotic target in human myeloid tumor cells. FASEB J (2011) 0.89
Clathrin is required for Scar/Wave-mediated lamellipodium formation. J Cell Sci (2011) 0.88
C5-DNA methyltransferase inhibitors: from screening to effects on zebrafish embryo development. Chembiochem (2011) 0.88
Epithelial morphogenesis and intestinal cancer: new insights in signaling mechanisms. Adv Cancer Res (2008) 0.87
APC inactivation associates with abnormal mitosis completion and concomitant BUB1B/MAD2L1 up-regulation. Gastroenterology (2007) 0.87
A new nidovirus (NamDinh virus NDiV): Its ultrastructural characterization in the C6/36 mosquito cell line. Virology (2013) 0.86
MICAL-like1 mediates epidermal growth factor receptor endocytosis. Mol Biol Cell (2011) 0.85
Isolation and characterization of an aggresome determinant in the NF2 tumor suppressor. J Biol Chem (2002) 0.84
Flavones and polyphenols inhibit the NO pathway during apoptosis of leukemia B-cells. Leuk Res (2004) 0.83
Myosin VI regulates actin dynamics and melanosome biogenesis. Traffic (2012) 0.83
Synthesis and biological activity of sulfonamide derivatives of epipodophyllotoxin. J Med Chem (2004) 0.83
Ezrin ubiquitylation by the E3 ubiquitin ligase, WWP1, and consequent regulation of hepatocyte growth factor receptor activity. PLoS One (2012) 0.83
In vitro and in vivo biological evaluation of new 4,5-disubstituted 1,2,3-triazoles as cis-constrained analogs of combretastatin A4. Eur J Med Chem (2012) 0.82
Post-translational amino acid racemization in the frog skin peptide deltorphin I in the secretion granules of cutaneous serous glands. Eur J Cell Biol (2005) 0.81
In vivo tumor targeting using a novel intestinal pathogen-based delivery approach. Cancer Res (2006) 0.81
Rafts are required for acetylcholine receptor clustering. J Mol Neurosci (2006) 0.81
Caveolins and flotillin-2 are present in the blood stages of Plasmodium vivax. Parasitol Res (2006) 0.80
Molecular basis of the targeting of topoisomerase II-mediated DNA cleavage by VP16 derivatives conjugated to triplex-forming oligonucleotides. Nucleic Acids Res (2006) 0.80
p70S6 kinase is a target of the novel proteasome inhibitor 3,3'-diamino-4'-methoxyflavone during apoptosis in human myeloid tumor cells. Biochim Biophys Acta (2013) 0.80
Synthesis and biological evaluation of novel flavone-8-acetic acid derivatives as reversible inhibitors of aminopeptidase N/CD13. J Med Chem (2003) 0.79
Triple helix-forming oligonucleotides conjugated to new inhibitors of topoisomerase II: synthesis and binding properties. Bioconjug Chem (2005) 0.79
Contributions of the D-Ring to the activity of etoposide against human topoisomerase IIα: potential interactions with DNA in the ternary enzyme--drug--DNA complex. Biochemistry (2011) 0.78
RNAi depleted Drosophila cell extracts to dissect signaling pathways leading to actin polymerization. J Biochem Biophys Methods (2007) 0.77
Correlation between electron-donating ability of a series of 3-nitroflavones and their efficacy to inhibit the onset and progression of aberrant crypt foci in the rat colon. Cancer Res (2002) 0.76
Identification of new flavone-8-acetic acid metabolites using mouse microsomes and comparison with human microsomes. Drug Metab Dispos (2007) 0.76
Traffic pathways of Plasmodium vivax antigens during intraerythrocytic parasite development. Parasitol Res (2002) 0.76
Assay of Rab13 in regulating epithelial tight junction assembly. Methods Enzymol (2005) 0.76
In vivo evolution of metabolic pathways: Assembling old parts to build novel and functional structures. Bioengineered (2014) 0.75
Not flavone-8-acetic acid (FAA) but its murine metabolite 6-OH-FAA exhibits remarkable antivascular activities in vitro. Anticancer Drugs (2016) 0.75
Electrospray tandem mass spectrometry of beta-nitroalkenyl meso-tetraphenylporphyrins. Eur J Mass Spectrom (Chichester, Eng) (2008) 0.75
Novel carbamate derivatives of 4-beta-amino-4'-O-demethyl-4-desoxypodophyllotoxin as inhibitors of topoisomerase II: synthesis and biological evaluation. Org Biomol Chem (2005) 0.75
The inducible NO synthase is downregulated during apoptosis of malignant cells from B-cell chronic lymphocytic leukemia induced by flavopiridol and polyphenols. Ann N Y Acad Sci (2003) 0.75
Properties of Rab13 interaction with protein kinase A. Methods Enzymol (2005) 0.75
Heterogeneous metastasis efficiency of isogenic orthotopic colon cancer xenografts reveals distinctive gene expression profiles. Tumour Biol (2007) 0.75
Characterization of monohydroxylated derivatives of the anticancer agent flavone-8-acetic acid by liquid chromatography with on-line UV and mass spectrometry. Rapid Commun Mass Spectrom (2007) 0.75
[Notch signals control the fate of immature progenitor cells in the intestine]. Med Sci (Paris) (2005) 0.75