New IL-17 family members promote Th1 or Th2 responses in the lung: in vivo function of the novel cytokine IL-25.

PubWeight™: 4.48‹?› | Rank: Top 1%

🔗 View Article (PMID 12077275)

Published in J Immunol on July 01, 2002

Authors

Stephen D Hurst1, Tony Muchamuel, Daniel M Gorman, Jonathan M Gilbert, Theresa Clifford, Sylvia Kwan, Satish Menon, Brian Seymour, Craig Jackson, Ted T Kung, Joan K Brieland, Sandra M Zurawski, Richard W Chapman, Gerard Zurawski, Robert L Coffman

Author Affiliations

1: DNAX Research Institute of Molecular and Cellular Biology, Palo Alto, CA 94304, USA. hurst@corgentech.com

Articles citing this

(truncated to the top 100)

The biological functions of T helper 17 cell effector cytokines in inflammation. Immunity (2008) 10.55

Innate lymphoid cells--a proposal for uniform nomenclature. Nat Rev Immunol (2013) 7.94

Innate IL-17-producing cells: the sentinels of the immune system. Nat Rev Immunol (2010) 6.88

Systemically dispersed innate IL-13-expressing cells in type 2 immunity. Proc Natl Acad Sci U S A (2010) 6.78

Structure and signalling in the IL-17 receptor family. Nat Rev Immunol (2009) 6.38

Divergent roles of IL-23 and IL-12 in host defense against Klebsiella pneumoniae. J Exp Med (2005) 6.37

The expanding family of innate lymphoid cells: regulators and effectors of immunity and tissue remodeling. Nat Immunol (2010) 6.02

Regulation of inflammatory responses by IL-17F. J Exp Med (2008) 5.56

Identification of an interleukin (IL)-25-dependent cell population that provides IL-4, IL-5, and IL-13 at the onset of helminth expulsion. J Exp Med (2006) 5.35

IL25 elicits a multipotent progenitor cell population that promotes T(H)2 cytokine responses. Nature (2010) 5.07

Human IL-25- and IL-33-responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161. Nat Immunol (2011) 5.05

Interleukin 25 promotes the initiation of proallergic type 2 responses. J Exp Med (2007) 3.91

IL-25 regulates Th17 function in autoimmune inflammation. J Exp Med (2007) 3.69

IL-25 augments type 2 immune responses by enhancing the expansion and functions of TSLP-DC-activated Th2 memory cells. J Exp Med (2007) 3.66

Innate lymphoid cells--how did we miss them? Nat Rev Immunol (2013) 3.62

Role of IL-17A, IL-17F, and the IL-17 receptor in regulating growth-related oncogene-alpha and granulocyte colony-stimulating factor in bronchial epithelium: implications for airway inflammation in cystic fibrosis. J Immunol (2005) 3.47

Interleukin 25 regulates type 2 cytokine-dependent immunity and limits chronic inflammation in the gastrointestinal tract. J Exp Med (2006) 3.36

Welcome to the neighborhood: epithelial cell-derived cytokines license innate and adaptive immune responses at mucosal sites. Immunol Rev (2008) 3.33

Th17 cells and mucosal host defense. Semin Immunol (2007) 3.17

Innate lymphoid type 2 cells sustain visceral adipose tissue eosinophils and alternatively activated macrophages. J Exp Med (2013) 2.79

The many paths to asthma: phenotype shaped by innate and adaptive immunity. Nat Immunol (2010) 2.74

An IL-9 fate reporter demonstrates the induction of an innate IL-9 response in lung inflammation. Nat Immunol (2011) 2.69

The role of T-cell interleukin-17 in conducting destructive arthritis: lessons from animal models. Arthritis Res Ther (2004) 2.54

TH2, allergy and group 2 innate lymphoid cells. Nat Immunol (2013) 2.52

Asthma and allergic inflammation. Cell (2010) 2.21

Structure-function relationships in the IL-17 receptor: implications for signal transduction and therapy. Cytokine (2008) 2.19

The airway epithelium: soldier in the fight against respiratory viruses. Clin Microbiol Rev (2011) 2.05

IL-17C regulates the innate immune function of epithelial cells in an autocrine manner. Nat Immunol (2011) 1.95

Innate cells and T helper 2 cell immunity in airway inflammation. Immunity (2009) 1.94

A novel subset of mouse NKT cells bearing the IL-17 receptor B responds to IL-25 and contributes to airway hyperreactivity. J Exp Med (2008) 1.94

Development, differentiation, and diversity of innate lymphoid cells. Immunity (2014) 1.87

IL-17 family member cytokines: regulation and function in innate immunity. Cytokine Growth Factor Rev (2010) 1.76

The adaptor protein CIKS/Act1 is essential for IL-25-mediated allergic airway inflammation. J Immunol (2009) 1.76

IL-9-mediated survival of type 2 innate lymphoid cells promotes damage control in helminth-induced lung inflammation. J Exp Med (2013) 1.75

Aspergillus fumigatus: principles of pathogenesis and host defense. Eukaryot Cell (2007) 1.74

Interleukin-1α controls allergic sensitization to inhaled house dust mite via the epithelial release of GM-CSF and IL-33. J Exp Med (2012) 1.69

The critical role of epithelial-derived Act1 in IL-17- and IL-25-mediated pulmonary inflammation. J Immunol (2009) 1.67

Signaling of interleukin-17 family cytokines in immunity and inflammation. Cell Signal (2010) 1.66

IL-17F: regulation, signaling and function in inflammation. Cytokine (2009) 1.56

The interleukin-17 cytokine family: critical players in host defence and inflammatory diseases. Immunology (2011) 1.53

Thymic stromal lymphopoietin, OX40-ligand, and interleukin-25 in allergic responses. Clin Exp Allergy (2009) 1.49

Prostaglandin D2 activates group 2 innate lymphoid cells through chemoattractant receptor-homologous molecule expressed on TH2 cells. J Allergy Clin Immunol (2013) 1.47

Critical role of IL-25 in nematode infection-induced alterations in intestinal function. J Immunol (2010) 1.40

Regulation and pro-inflammatory function of interleukin-17 family cytokines. Immunol Rev (2008) 1.36

Immunopathology of inflammatory bowel disease. World J Gastroenterol (2014) 1.36

Essential, dose-dependent role for the transcription factor Gata3 in the development of IL-5+ and IL-13+ type 2 innate lymphoid cells. Proc Natl Acad Sci U S A (2013) 1.34

Tuft-cell-derived IL-25 regulates an intestinal ILC2-epithelial response circuit. Nature (2015) 1.29

Innate lymphoid cells: balancing immunity, inflammation, and tissue repair in the intestine. Cell Host Microbe (2012) 1.29

Immunopathology of chronic rhinosinusitis. Allergol Int (2015) 1.28

Type 2 innate immune responses and the natural helper cell. Immunology (2011) 1.24

Development and function of group 2 innate lymphoid cells. Curr Opin Immunol (2013) 1.24

The IL-17 cytokine family and their role in allergic inflammation. Curr Opin Immunol (2008) 1.23

Induction of airway hyperreactivity by IL-25 is dependent on a subset of invariant NKT cells expressing IL-17RB. J Immunol (2009) 1.18

The IL-17 family cytokines in immunity and disease. J Clin Immunol (2010) 1.16

Dynamic role of epithelium-derived cytokines in asthma. Clin Immunol (2012) 1.14

T-helper cell type 2 (Th2) memory T cell-potentiating cytokine IL-25 has the potential to promote angiogenesis in asthma. Proc Natl Acad Sci U S A (2011) 1.13

IL-17 signaling in host defense and inflammatory diseases. Cell Mol Immunol (2010) 1.11

T-cell subset regulation in atopy. Curr Allergy Asthma Rep (2011) 1.09

Epithelial interleukin-25 is a key mediator in Th2-high, corticosteroid-responsive asthma. Am J Respir Crit Care Med (2014) 1.09

Role of innate lymphocytes in infection and inflammation. Front Immunol (2012) 1.08

Epithelial cell-derived IL-25, but not Th17 cell-derived IL-17 or IL-17F, is crucial for murine asthma. J Immunol (2012) 1.08

Blocking IL-25 signalling protects against gut inflammation in a type-2 model of colitis by suppressing nuocyte and NKT derived IL-13. J Gastroenterol (2012) 1.04

Current views on the functions of interleukin-17A-producing cells in atherosclerosis. Thromb Haemost (2011) 1.03

Th17 cells and regulatory T cells in elite control over HIV and SIV. Curr Opin HIV AIDS (2011) 1.01

A CC' loop decoy peptide blocks the interaction between Act1 and IL-17RA to attenuate IL-17- and IL-25-induced inflammation. Sci Signal (2011) 0.98

Protease allergens induce the expression of IL-25 via Erk and p38 MAPK pathway. J Korean Med Sci (2010) 0.97

Fms-like tyrosine kinase 3 ligand decreases T helper type 17 cells and suppressors of cytokine signaling proteins in the lung of house dust mite-sensitized and -challenged mice. Am J Respir Cell Mol Biol (2009) 0.96

IL-1β suppresses innate IL-25 and IL-33 production and maintains helminth chronicity. PLoS Pathog (2013) 0.96

Tumor necrosis factor α-mediated induction of interleukin 17C in human keratinocytes is controlled by nuclear factor κB. J Biol Chem (2011) 0.94

IL-7: the global builder of the innate lymphoid network and beyond, one niche at a time. Semin Immunol (2012) 0.94

T cell-derived Act1 is necessary for IL-25-mediated Th2 responses and allergic airway inflammation. J Immunol (2011) 0.93

Regulatory mechanisms of helper T cell differentiation: new lessons learned from interleukin 17 family cytokines. Pharmacol Ther (2008) 0.93

Host protective roles of type 2 immunity: parasite killing and tissue repair, flip sides of the same coin. Semin Immunol (2014) 0.93

Airway generation-specific differences in the spatial distribution of immune cells and cytokines in allergen-challenged rhesus monkeys. Clin Exp Allergy (2005) 0.93

Acute infection of mice with Clostridium difficile leads to eIF2α phosphorylation and pro-survival signalling as part of the mucosal inflammatory response. Immunology (2013) 0.93

Identification of a novel antigen-presenting cell population modulating antiinfluenza type 2 immunity. J Exp Med (2010) 0.92

Group 2 innate lymphoid cells: new players in human allergic diseases. J Investig Allergol Clin Immunol (2015) 0.92

Detection of Allergen Specific Antibodies From Nasal Secretion of Allergic Rhinitis Patients. Allergy Asthma Immunol Res (2016) 0.92

Novel chimeric immunomodulatory compounds containing short CpG oligodeoxyribonucleotides have differential activities in human cells. Nucleic Acids Res (2003) 0.91

Type 2 Innate Lymphoid Cells in Allergic Disease. Curr Immunol Rev (2013) 0.91

Recent advances in mechanisms and treatments of airway remodeling in asthma: a message from the bench side to the clinic. Korean J Intern Med (2011) 0.90

Cytokines (interleukin-9, IL-17, IL-22, IL-25 and IL-33) and asthma. Adv Biomed Res (2014) 0.89

Innate lymphoid cells in the defense against infections. Eur J Microbiol Immunol (Bp) (2013) 0.88

Mechanisms of tolerance induction in allergic disease: integrating current and emerging concepts. Clin Exp Allergy (2013) 0.88

At the bench: understanding group 2 innate lymphoid cells in disease. J Leukoc Biol (2014) 0.87

Protease-activated receptor 2 is involved in Th2 responses against Trichinella spiralis infection. Korean J Parasitol (2011) 0.86

The role of peroxisome proliferator-activated receptor γ in immune responses to enteroaggregative Escherichia coli infection. PLoS One (2013) 0.86

Group 2 innate lymphoid cells in lung inflammation. Immunology (2013) 0.86

Potential involvement of IL-17F in asthma. J Immunol Res (2014) 0.85

The other T helper cells in asthma pathogenesis. J Allergy (Cairo) (2010) 0.84

Collaborative interactions between type 2 innate lymphoid cells and antigen-specific CD4+ Th2 cells exacerbate murine allergic airway diseases with prominent eosinophilia. J Immunol (2015) 0.84

IL-25 and CD4(+) TH2 cells enhance type 2 innate lymphoid cell-derived IL-13 production, which promotes IgE-mediated experimental food allergy. J Allergy Clin Immunol (2015) 0.84

Maintenance of Immune Homeostasis through ILC/T Cell Interactions. Front Immunol (2015) 0.83

Grape seed proanthocyanidin extract protects against carrageenan-induced lung inflammation in mice through reduction of pro-inflammatory markers and chemokine expressions. Inflammation (2014) 0.82

STAT3-mediated IL-17 production by postseptic T cells exacerbates viral immunopathology of the lung. Shock (2012) 0.82

Regulation of IL-17 family members by adrenal hormones during experimental sepsis in mice. Am J Pathol (2013) 0.82

Molecular analysis of interleukin-25 exons 1 and 2 and its serum levels in Iranian patients with multiple sclerosis. Am J Clin Exp Immunol (2014) 0.81

Group 2 innate lymphoid cell proportions are diminished in young helminth infected children and restored by curative anti-helminthic treatment. PLoS Negl Trop Dis (2015) 0.81

The roles of innate lymphoid cells in the development of asthma. Immune Netw (2014) 0.81

Innate lymphocyte cells in asthma phenotypes. Clin Transl Allergy (2015) 0.81

Articles by these authors

Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain. Nature (2003) 22.89

IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines. Immunity (2005) 14.95

Human epithelial cells trigger dendritic cell mediated allergic inflammation by producing TSLP. Nat Immunol (2002) 10.15

IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells. Immunity (2002) 8.19

Human blood CXCR5(+)CD4(+) T cells are counterparts of T follicular cells and contain specific subsets that differentially support antibody secretion. Immunity (2011) 5.98

In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines. J Exp Med (2002) 5.28

Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus. J Exp Med (2005) 4.92

Divergent TLR7 and TLR9 signaling and type I interferon production distinguish pathogenic and nonpathogenic AIDS virus infections. Nat Med (2008) 4.55

Netting neutrophils are major inducers of type I IFN production in pediatric systemic lupus erythematosus. Sci Transl Med (2011) 4.51

Therapeutic targeting of innate immunity with Toll-like receptor agonists and antagonists. Nat Med (2007) 4.39

IL-23 induces spondyloarthropathy by acting on ROR-γt+ CD3+CD4-CD8- entheseal resident T cells. Nat Med (2012) 4.38

T cells that cannot respond to TGF-beta escape control by CD4(+)CD25(+) regulatory T cells. J Exp Med (2005) 4.28

Functional specializations of human epidermal Langerhans cells and CD14+ dermal dendritic cells. Immunity (2008) 3.94

IL-25 regulates Th17 function in autoimmune inflammation. J Exp Med (2007) 3.69

IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesis. J Exp Med (2006) 3.38

Human dendritic cells induce the differentiation of interleukin-21-producing T follicular helper-like cells through interleukin-12. Immunity (2009) 3.13

Thymic stromal lymphopoietin fosters human breast tumor growth by promoting type 2 inflammation. J Exp Med (2011) 3.12

Skin-resident murine dendritic cell subsets promote distinct and opposing antigen-specific T helper cell responses. Immunity (2011) 2.58

Properties regulating the nature of the plasmacytoid dendritic cell response to Toll-like receptor 9 activation. J Exp Med (2006) 2.57

Nonproteasomal targets of the proteasome inhibitors bortezomib and carfilzomib: a link to clinical adverse events. Clin Cancer Res (2011) 2.56

Treatment of lupus-prone mice with a dual inhibitor of TLR7 and TLR9 leads to reduction of autoantibody production and amelioration of disease symptoms. Eur J Immunol (2007) 2.32

TLR recognition of self nucleic acids hampers glucocorticoid activity in lupus. Nature (2010) 2.31

Human TLR-7-, -8-, and -9-mediated induction of IFN-alpha/beta and -lambda Is IRAK-4 dependent and redundant for protective immunity to viruses. Immunity (2005) 2.16

A restricted subset of dendritic cells captures airborne antigens and remains able to activate specific T cells long after antigen exposure. Immunity (2002) 2.09

Systems scale interactive exploration reveals quantitative and qualitative differences in response to influenza and pneumococcal vaccines. Immunity (2013) 2.08

Toll-like receptor recognition regulates immunodominance in an antimicrobial CD4+ T cell response. Immunity (2006) 2.05

Beneficial effect of novel proteasome inhibitors in murine lupus via dual inhibition of type I interferon and autoantibody-secreting cells. Arthritis Rheum (2012) 2.03

PI3K is critical for the nuclear translocation of IRF-7 and type I IFN production by human plasmacytoid predendritic cells in response to TLR activation. J Exp Med (2008) 2.02

Development of TLR inhibitors for the treatment of autoimmune diseases. Immunol Rev (2008) 1.90

Autoimmune skin inflammation is dependent on plasmacytoid dendritic cell activation by nucleic acids via TLR7 and TLR9. J Exp Med (2010) 1.88

Interleukin-10 (IL-10) in experimental visceral leishmaniasis and IL-10 receptor blockade as immunotherapy. Infect Immun (2002) 1.85

Interleukin-22 activates STAT3 and induces IL-10 by colon epithelial cells. Int Immunopharmacol (2004) 1.80

Murine CXCR1 is a functional receptor for GCP-2/CXCL6 and interleukin-8/CXCL8. J Biol Chem (2006) 1.79

Selective utilization of Toll-like receptor and MyD88 signaling in B cells for enhancement of the antiviral germinal center response. Immunity (2011) 1.70

Identification of a novel CpG DNA class and motif that optimally stimulate B cell and plasmacytoid dendritic cell functions. J Leukoc Biol (2003) 1.65

RNA recognition by human TLR8 can lead to autoimmune inflammation. J Exp Med (2013) 1.64

Cross-priming CD8+ T cells by targeting antigens to human dendritic cells through DCIR. Blood (2010) 1.55

Targeting self- and foreign antigens to dendritic cells via DC-ASGPR generates IL-10-producing suppressive CD4+ T cells. J Exp Med (2012) 1.50

Design and synthesis of an orally bioavailable and selective peptide epoxyketone proteasome inhibitor (PR-047). J Med Chem (2009) 1.50

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. 1986. J Immunol (2005) 1.48

Harnessing human dendritic cell subsets for medicine. Immunol Rev (2010) 1.46

Surface phenotype of Peyer's patch germinal center cells: implications for the role of germinal centers in B cell differentiation. 1982. J Immunol (2005) 1.45

Oxazolidinones inhibit cellular proliferation via inhibition of mitochondrial protein synthesis. Antimicrob Agents Chemother (2005) 1.44

IL-10 regulates plasmacytoid dendritic cell response to CpG-containing immunostimulatory sequences. Blood (2003) 1.39

Inhibitors of TLR-9 act on multiple cell subsets in mouse and man in vitro and prevent death in vivo from systemic inflammation. J Immunol (2005) 1.36

Inflammatory mediators in uveitis: differential induction of cytokines and chemokines in Th1- versus Th2-mediated ocular inflammation. J Immunol (2002) 1.33

A novel, orally active CXCR1/2 receptor antagonist, Sch527123, inhibits neutrophil recruitment, mucus production, and goblet cell hyperplasia in animal models of pulmonary inflammation. J Pharmacol Exp Ther (2007) 1.30

IL-10 directly activates and expands tumor-resident CD8(+) T cells without de novo infiltration from secondary lymphoid organs. Cancer Res (2012) 1.27

Next generation sequencing in research and diagnostics of ocular birth defects. Mol Genet Metab (2010) 1.21

Immunostimulatory oligonucleotides block allergic airway inflammation by inhibiting Th2 cell activation and IgE-mediated cytokine induction. J Exp Med (2005) 1.20

Transforming growth factor beta specifically enhances IgA production by lipopolysaccharide-stimulated murine B lymphocytes. J. Exp. Med. 1989. 170: 1039-1044. J Immunol (2009) 1.20

A novel cannabinoid peripheral cannabinoid receptor-selective inverse agonist blocks leukocyte recruitment in vivo. J Pharmacol Exp Ther (2005) 1.20

Microarray profile of differentially expressed genes in a monkey model of allergic asthma. Genome Biol (2002) 1.20

Innovations and developments in surgical coloproctology. J R Soc Med (2013) 1.16

Concomitant activation and antigen uptake via human dectin-1 results in potent antigen-specific CD8+ T cell responses. J Immunol (2010) 1.16

The differential production of cytokines by human Langerhans cells and dermal CD14(+) DCs controls CTL priming. Blood (2012) 1.15

The CD200 receptor is a novel and potent regulator of murine and human mast cell function. J Immunol (2005) 1.15

Combination immunotherapy with a CpG oligonucleotide (1018 ISS) and rituximab in patients with non-Hodgkin lymphoma: increased interferon-alpha/beta-inducible gene expression, without significant toxicity. Blood (2004) 1.13

Broad influenza-specific CD8+ T-cell responses in humanized mice vaccinated with influenza virus vaccines. Blood (2008) 1.12

CpG oligodeoxynucleotides alter lymphocyte and dendritic cell trafficking in humans. Clin Cancer Res (2008) 1.11

Targeting human dendritic cell subsets for improved vaccines. Semin Immunol (2011) 1.09

Serum from patients with SLE instructs monocytes to promote IgG and IgA plasmablast differentiation. J Exp Med (2012) 1.08

Immunostimulatory sequences regulate interferon-inducible genes but not allergic airway responses. Am J Respir Crit Care Med (2006) 1.02

Assessing the safety of adjuvanted vaccines. Sci Transl Med (2011) 1.01

Role of the chemokine stromal cell-derived factor 1 in autoantibody production and nephritis in murine lupus. J Immunol (2003) 1.00

OSCAR is an FcRgamma-associated receptor that is expressed by myeloid cells and is involved in antigen presentation and activation of human dendritic cells. Blood (2004) 1.00

The Enamovirus P0 protein is a silencing suppressor which inhibits local and systemic RNA silencing through AGO1 degradation. Virology (2012) 0.99

Transgenic mice expressing human interleukin-10 in the antigen-presenting cell compartment show increased susceptibility to infection with Mycobacterium avium associated with decreased macrophage effector function and apoptosis. Infect Immun (2002) 0.99

Noncovalent assembly of anti-dendritic cell antibodies and antigens for evoking immune responses in vitro and in vivo. J Immunol (2012) 0.97

CpG-containing immunostimulatory DNA sequences elicit TNF-alpha-dependent toxicity in rodents but not in humans. J Clin Invest (2009) 0.96

Superior activity of the type C class of ISS in vitro and in vivo across multiple species. DNA Cell Biol (2005) 0.96

Targeting concatenated HIV antigens to human CD40 expands a broad repertoire of multifunctional CD4+ and CD8+ T cells. AIDS (2013) 0.96

Inhibition of the immunoproteasome ameliorates experimental autoimmune encephalomyelitis. EMBO Mol Med (2014) 0.95

Immunoglobulin-like transcript receptors on human dermal CD14+ dendritic cells act as a CD8-antagonist to control cytotoxic T cell priming. Proc Natl Acad Sci U S A (2012) 0.93

Anti-IL-17A therapy protects against bone erosion in experimental models of rheumatoid arthritis. Autoimmunity (2010) 0.93

Building on dendritic cell subsets to improve cancer vaccines. Curr Opin Immunol (2010) 0.93

Gender differences in the allergic response of mice neonatally exposed to environmental tobacco smoke. Dev Immunol (2002) 0.93

Brucella β 1,2 cyclic glucan is an activator of human and mouse dendritic cells. PLoS Pathog (2012) 0.92

Friend of GATA is expressed in naive Th cells and functions as a repressor of GATA-3-mediated Th2 cell development. J Immunol (2002) 0.91

Novel chimeric immunomodulatory compounds containing short CpG oligodeoxyribonucleotides have differential activities in human cells. Nucleic Acids Res (2003) 0.91

Identification of risk factors for postoperative nausea and vomiting in the perianesthesia adult patient. J Perianesth Nurs (2006) 0.89

Cough reflex in allergic dogs. Eur J Pharmacol (2004) 0.88

Molecular cloning of doublesex genes of four cladocera (water flea) species. BMC Genomics (2013) 0.88

Second-hand smoke increases bronchial hyperreactivity and eosinophilia in a murine model of allergic aspergillosis. Clin Dev Immunol (2003) 0.86

Inhibition of spleen tyrosine kinase attenuates allergen-mediated airway constriction. Am J Respir Cell Mol Biol (2013) 0.86

Induction of lysosomal and plasma membrane-bound sialidases in human T-cells via T-cell receptor. Biochem J (2004) 0.86

Diffusion tensor imaging detects treatment effects of FTY720 in experimental autoimmune encephalomyelitis mice. NMR Biomed (2013) 0.85

An enzyme-linked immunosorbent assay (ELISA) for the determination of mucin levels in bronchoalveolar lavage fluid. J Pharmacol Toxicol Methods (2005) 0.85

Differential regulation of lymphoproliferative responses to Trypanosoma cruzi antigen in patients with the cardiac or indeterminate form of Chagas disease. Clin Immunol (2004) 0.85

Influenza virus and poly(I:C) inhibit MHC class I-restricted presentation of cell-associated antigens derived from infected dead cells captured by human dendritic cells. J Immunol (2009) 0.84

Non-viral delivery of nuclear factor-kappaB decoy ameliorates murine inflammatory bowel disease and restores tissue homeostasis. Gut (2006) 0.84

Blockade of experimental atopic dermatitis via topical NF-kappaB decoy oligonucleotide. J Invest Dermatol (2006) 0.84

CD34-derived dendritic cells transfected ex vivo with HIV-Gag mRNA induce polyfunctional T-cell responses in nonhuman primates. Eur J Immunol (2012) 0.83

A minimal human immunostimulatory CpG motif that potently induces IFN-gamma and IFN-alpha production. Eur J Immunol (2003) 0.83