Published in Carcinogenesis on July 01, 2002
Human Fanconi anemia monoubiquitination pathway promotes homologous DNA repair. Proc Natl Acad Sci U S A (2005) 3.93
Repair kinetics of genomic interstrand DNA cross-links: evidence for DNA double-strand break-dependent activation of the Fanconi anemia/BRCA pathway. Mol Cell Biol (2004) 2.20
Fanconi anemia FANCG protein in mitigating radiation- and enzyme-induced DNA double-strand breaks by homologous recombination in vertebrate cells. Mol Cell Biol (2003) 1.84
Cellular and molecular consequences of defective Fanconi anemia proteins in replication-coupled DNA repair: mechanistic insights. Mutat Res (2009) 1.80
Hypomorphic mutations in the gene encoding a key Fanconi anemia protein, FANCD2, sustain a significant group of FA-D2 patients with severe phenotype. Am J Hum Genet (2007) 1.67
DOG-1 is the Caenorhabditis elegans BRIP1/FANCJ homologue and functions in interstrand cross-link repair. Mol Cell Biol (2007) 1.53
XPF-ERCC1 participates in the Fanconi anemia pathway of cross-link repair. Mol Cell Biol (2009) 1.50
An ATR- and BRCA1-mediated Fanconi anemia pathway is required for activating the G2/M checkpoint and DNA damage repair upon rereplication. Mol Cell Biol (2006) 1.27
Pathways for repairing and tolerating the spectrum of oxidative DNA lesions. Cancer Lett (2012) 1.20
The Fanconi anemia pathway and ubiquitin. BMC Biochem (2007) 1.10
Fanconi anemia proteins, DNA interstrand crosslink repair pathways, and cancer therapy. Curr Cancer Drug Targets (2009) 1.00
Biomarkers and mechanisms of FANCD2 function. J Biomed Biotechnol (2008) 0.89
FANC pathway promotes UV-induced stalled replication forks recovery by acting both upstream and downstream Polη and Rev1. PLoS One (2013) 0.87
Impaired TIP60-mediated H4K16 acetylation accounts for the aberrant chromatin accumulation of 53BP1 and RAP80 in Fanconi anemia pathway-deficient cells. Nucleic Acids Res (2015) 0.85
FANCD2-deficient human fibroblasts are hypersensitive to ionising radiation at oxygen concentrations of 0% and 3% but not under normoxic conditions. Int J Radiat Biol (2009) 0.84
DNA Damage Response Assessments in Human Tumor Samples Provide Functional Biomarkers of Radiosensitivity. Semin Radiat Oncol (2015) 0.84
The phenotype of FancB-mutant mouse embryonic stem cells. Mutat Res (2011) 0.81
FANCD2 influences replication fork processes and genome stability in response to clustered DSBs. Cell Cycle (2015) 0.77
C. elegans ring finger protein RNF-113 is involved in interstrand DNA crosslink repair and interacts with a RAD51C homolog. PLoS One (2013) 0.77
Biallelic inactivation of BRCA2 in Fanconi anemia. Science (2002) 9.31
Cell fusion is the principal source of bone-marrow-derived hepatocytes. Nature (2003) 6.92
The Fanconi anaemia/BRCA pathway. Nat Rev Cancer (2003) 5.89
Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene. Nat Genet (2010) 5.48
Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N and predispose to childhood cancer. Nat Genet (2006) 5.12
Robust expansion of human hepatocytes in Fah-/-/Rag2-/-/Il2rg-/- mice. Nat Biotechnol (2007) 5.04
In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration. Nature (2013) 4.94
S-phase-specific interaction of the Fanconi anemia protein, FANCD2, with BRCA1 and RAD51. Blood (2002) 4.27
Generation and regeneration of cells of the liver and pancreas. Science (2008) 4.21
The BRCA1-interacting helicase BRIP1 is deficient in Fanconi anemia. Nat Genet (2005) 4.13
Mutations in the pericentrin (PCNT) gene cause primordial dwarfism. Science (2008) 4.04
Myelomonocytic cells are sufficient for therapeutic cell fusion in liver. Nat Med (2004) 3.77
SLX4, a coordinator of structure-specific endonucleases, is mutated in a new Fanconi anemia subtype. Nat Genet (2011) 3.74
Epithelial cancer in Fanconi anemia complementation group D2 (Fancd2) knockout mice. Genes Dev (2003) 3.58
Mutation of the RAD51C gene in a Fanconi anemia-like disorder. Nat Genet (2010) 3.57
Stem cells and liver regeneration. Gastroenterology (2009) 3.40
Intracytoplasmic sperm injection may increase the risk of imprinting defects. Am J Hum Genet (2002) 3.34
The ploidy conveyor of mature hepatocytes as a source of genetic variation. Nature (2010) 3.27
The origin and liver repopulating capacity of murine oval cells. Proc Natl Acad Sci U S A (2003) 2.99
AAV serotype 2 vectors preferentially integrate into active genes in mice. Nat Genet (2003) 2.81
The multiple sulfatase deficiency gene encodes an essential and limiting factor for the activity of sulfatases. Cell (2003) 2.71
Foxl1-Cre-marked adult hepatic progenitors have clonogenic and bilineage differentiation potential. Genes Dev (2011) 2.53
Identification of the Fanconi anemia complementation group I gene, FANCI. Cell Oncol (2007) 2.50
Epigenomic plasticity enables human pancreatic α to β cell reprogramming. J Clin Invest (2013) 2.38
A histone-fold complex and FANCM form a conserved DNA-remodeling complex to maintain genome stability. Mol Cell (2010) 2.36
Clinical applications of magnetic nanoparticles for hyperthermia. Int J Hyperthermia (2008) 2.32
Bone marrow failure in Fanconi anemia is triggered by an exacerbated p53/p21 DNA damage response that impairs hematopoietic stem and progenitor cells. Cell Stem Cell (2012) 2.26
Intracranial thermotherapy using magnetic nanoparticles combined with external beam radiotherapy: results of a feasibility study on patients with glioblastoma multiforme. J Neurooncol (2006) 2.22
Repair kinetics of genomic interstrand DNA cross-links: evidence for DNA double-strand break-dependent activation of the Fanconi anemia/BRCA pathway. Mol Cell Biol (2004) 2.20
Prospective isolation of a bipotential clonogenic liver progenitor cell in adult mice. Genes Dev (2011) 2.17
Mutations in ERCC4, encoding the DNA-repair endonuclease XPF, cause Fanconi anemia. Am J Hum Genet (2013) 2.15
Myeloid lineage progenitors give rise to vascular endothelium. Proc Natl Acad Sci U S A (2006) 2.13
Large-scale molecular characterization of adeno-associated virus vector integration in mouse liver. J Virol (2005) 2.09
Regulated interaction of the Fanconi anemia protein, FANCD2, with chromatin. Blood (2004) 2.08
An essential function for NBS1 in the prevention of ataxia and cerebellar defects. Nat Med (2005) 2.06
Efficacy and safety of intratumoral thermotherapy using magnetic iron-oxide nanoparticles combined with external beam radiotherapy on patients with recurrent glioblastoma multiforme. J Neurooncol (2010) 2.02
FAAP100 is essential for activation of the Fanconi anemia-associated DNA damage response pathway. EMBO J (2007) 2.00
Thermotherapy of prostate cancer using magnetic nanoparticles: feasibility, imaging, and three-dimensional temperature distribution. Eur Urol (2006) 2.00
Mutations in the gene encoding the lamin B receptor produce an altered nuclear morphology in granulocytes (Pelger-Huët anomaly). Nat Genet (2002) 1.99
The effect of thermotherapy using magnetic nanoparticles on rat malignant glioma. J Neurooncol (2005) 1.89
Kinetics of liver repopulation after bone marrow transplantation. Am J Pathol (2002) 1.85
Anthracyclines induce DNA damage response-mediated protection against severe sepsis. Immunity (2013) 1.83
Bone marrow-derived cells fuse with normal and transformed intestinal stem cells. Proc Natl Acad Sci U S A (2006) 1.82
Therapeutic liver reconstitution with murine cells isolated long after death. Gastroenterology (2010) 1.78
Loss of p21 permits carcinogenesis from chronically damaged liver and kidney epithelial cells despite unchecked apoptosis. Cancer Cell (2008) 1.75
Notch signaling inhibits hepatocellular carcinoma following inactivation of the RB pathway. J Exp Med (2011) 1.74
Hypomorphic mutations in the gene encoding a key Fanconi anemia protein, FANCD2, sustain a significant group of FA-D2 patients with severe phenotype. Am J Hum Genet (2007) 1.67
Histone H2AX and Fanconi anemia FANCD2 function in the same pathway to maintain chromosome stability. EMBO J (2007) 1.65
Genotype-phenotype correlations in Fanconi anemia. Mutat Res (2009) 1.65
Surface markers for the murine oval cell response. Hepatology (2008) 1.65
Mutations in microcephalin cause aberrant regulation of chromosome condensation. Am J Hum Genet (2004) 1.62
In vivo correction of murine hereditary tyrosinemia type I by phiC31 integrase-mediated gene delivery. Mol Ther (2005) 1.59
Production of pluripotent stem cells by oocyte-assisted reprogramming: joint statement with signatories. Natl Cathol Bioeth Q (2005) 1.57
Small supernumerary marker chromosomes (SMCs): genotype-phenotype correlation and classification. Hum Genet (2003) 1.57
Mutations in PHF6 are associated with Börjeson-Forssman-Lehmann syndrome. Nat Genet (2002) 1.57
Human RAD50 deficiency in a Nijmegen breakage syndrome-like disorder. Am J Hum Genet (2009) 1.54
Gene therapy of metachromatic leukodystrophy reverses neurological damage and deficits in mice. J Clin Invest (2006) 1.54
Complete Plasmodium falciparum liver-stage development in liver-chimeric mice. J Clin Invest (2012) 1.52
Magnetic nanoparticles for interstitial thermotherapy--feasibility, tolerance and achieved temperatures. Int J Hyperthermia (2006) 1.50
Magnetic nanoparticle hyperthermia for prostate cancer. Int J Hyperthermia (2010) 1.50
A rapid method for retrovirus-mediated identification of complementation groups in Fanconi anemia patients. Mol Ther (2005) 1.48
Delayed diagnosis and complications of Fanconi anaemia at advanced age--a paradigm. Br J Haematol (2006) 1.48
Isolation of major pancreatic cell types and long-term culture-initiating cells using novel human surface markers. Stem Cell Res (2008) 1.45
Generation of monoclonal antibodies specific for cell surface molecules expressed on early mouse endoderm. Stem Cells (2009) 1.43
Warsaw breakage syndrome, a cohesinopathy associated with mutations in the XPD helicase family member DDX11/ChlR1. Am J Hum Genet (2010) 1.42
Mutational spectrum of the succinate semialdehyde dehydrogenase (ALDH5A1) gene and functional analysis of 27 novel disease-causing mutations in patients with SSADH deficiency. Hum Mutat (2003) 1.42
Nibrin functions in Ig class-switch recombination. Proc Natl Acad Sci U S A (2005) 1.41
Adeno-associated virus gene repair corrects a mouse model of hereditary tyrosinemia in vivo. Hepatology (2010) 1.41
In vivo correction of murine tyrosinemia type I by DNA-mediated transposition. Mol Ther (2002) 1.39
Seeking consensus: a clarification and defense of altered nuclear transfer. Hastings Cent Rep (2006) 1.39
A novel approach to describe a U1 snRNA binding site. Nucleic Acids Res (2003) 1.35
A novel mutation in GJA8 associated with jellyfish-like cataract in a family of Indian origin. Mol Vis (2008) 1.34
A novel mutation in the DNA-binding domain of MAF at 16q23.1 associated with autosomal dominant "cerulean cataract" in an Indian family. Am J Med Genet A (2006) 1.34
Nijmegen breakage syndrome: clinical manifestation of defective response to DNA double-strand breaks. DNA Repair (Amst) (2004) 1.33
Clonal tracing of Sox9+ liver progenitors in mouse oval cell injury. Hepatology (2014) 1.32
A severe form of human combined immunodeficiency due to mutations in DNA ligase IV. J Immunol (2006) 1.31
Frequent aneuploidy among normal human hepatocytes. Gastroenterology (2011) 1.30
A comprehensive strategy for the subtyping of patients with Fanconi anaemia: conclusions from the Spanish Fanconi Anemia Research Network. J Med Genet (2006) 1.30
Fancd2-/- mice have hematopoietic defects that can be partially corrected by resveratrol. Blood (2010) 1.29
Ploidy reductions in murine fusion-derived hepatocytes. PLoS Genet (2009) 1.28
Description and characterization of the novel hyperthermia- and thermoablation-system MFH 300F for clinical magnetic fluid hyperthermia. Med Phys (2004) 1.26
Deficiencies in the Fanconi anemia DNA damage response pathway increase sensitivity to HPV-associated head and neck cancer. Cancer Res (2010) 1.26
Genetic heterogeneity among Fanconi anemia heterozygotes and risk of cancer. Cancer Res (2007) 1.24
Aneuploidy as a mechanism for stress-induced liver adaptation. J Clin Invest (2012) 1.23
Mutations at the mouse ichthyosis locus are within the lamin B receptor gene: a single gene model for human Pelger-Huët anomaly. Hum Mol Genet (2003) 1.22
Roles of brca2 (fancd1) in oocyte nuclear architecture, gametogenesis, gonad tumors, and genome stability in zebrafish. PLoS Genet (2011) 1.22
Tempol protects against oxidative damage and delays epithelial tumor onset in Fanconi anemia mice. Cancer Res (2008) 1.22
The granulocyte nucleus and lamin B receptor: avoiding the ovoid. Chromosoma (2007) 1.21
The Fanconi anemia group A protein modulates homologous repair of DNA double-strand breaks in mammalian cells. Carcinogenesis (2005) 1.21
Misregulated chromosome condensation in MCPH1 primary microcephaly is mediated by condensin II. Cell Cycle (2006) 1.20
A novel mutation in GJA8 associated with autosomal dominant congenital cataract in a family of Indian origin. Mol Vis (2006) 1.20
Natural gene therapy in monozygotic twins with Fanconi anemia. Blood (2006) 1.20
Homologous sequences at human chromosome 9 bands p12 and q13-21.1 are involved in different patterns of pericentric rearrangements. Eur J Hum Genet (2002) 1.19
A ubiquitin-binding protein, FAAP20, links RNF8-mediated ubiquitination to the Fanconi anemia DNA repair network. Mol Cell (2012) 1.19