Published in J Antibiot (Tokyo) on May 01, 2002
An alternative menaquinone biosynthetic pathway operating in microorganisms. Science (2008) 2.46
Effect on tumor cells of blocking survival response to glucose deprivation. J Natl Cancer Inst (2004) 2.30
Telomestatin, a potent telomerase inhibitor that interacts quite specifically with the human telomeric intramolecular g-quadruplex. J Am Chem Soc (2002) 1.82
Telomestatin-induced telomere uncapping is modulated by POT1 through G-overhang extension in HT1080 human tumor cells. J Biol Chem (2006) 1.74
Chemical genomics identifies the unfolded protein response as a target for selective cancer cell killing during glucose deprivation. Cancer Res (2009) 1.53
Functional analysis of eubacterial diterpene cyclases responsible for biosynthesis of a diterpene antibiotic, terpentecin. J Biol Chem (2002) 1.48
Design and synthesis of an expanded porphyrin that has selectivity for the c-MYC G-quadruplex structure. J Am Chem Soc (2005) 1.40
Massadine, a novel geranylgeranyltransferase type I inhibitor from the marine sponge Stylissa aff. massa. Org Lett (2003) 1.34
Reevaluation of telomerase inhibition by quadruplex ligands and their mechanisms of action. Proc Natl Acad Sci U S A (2007) 1.29
Interaction of telomestatin with the telomeric single-strand overhang. J Biol Chem (2004) 1.27
Activity of a novel G-quadruplex-interactive telomerase inhibitor, telomestatin (SOT-095), against human leukemia cells: involvement of ATM-dependent DNA damage response pathways. Oncogene (2003) 1.26
Mammalian DNA2 helicase/nuclease cleaves G-quadruplex DNA and is required for telomere integrity. EMBO J (2013) 1.25
Biosynthesis of a natural polyketide-isoprenoid hybrid compound, furaquinocin A: identification and heterologous expression of the gene cluster. J Bacteriol (2006) 1.22
Studies on a new biosynthetic pathway for menaquinone. J Am Chem Soc (2008) 1.12
Macrocyclic and helical oligoamides as a new class of G-quadruplex ligands. J Am Chem Soc (2007) 1.10
Fanconi anemia group J mutation abolishes its DNA repair function by uncoupling DNA translocation from helicase activity or disruption of protein-DNA complexes. Blood (2010) 1.02
Maklamicin, an antibacterial polyketide from an endophytic Micromonospora sp. J Nat Prod (2011) 1.02
Thioviridamide, a novel apoptosis inducer in transformed cells from Streptomyces olivoviridis. J Antibiot (Tokyo) (2006) 0.98
Structure of thioviridamide, a novel apoptosis inducer from Streptomyces olivoviridis. J Antibiot (Tokyo) (2006) 0.96
A relationship between the mevalonate pathway and isoprenoid production in actinomycetes. J Antibiot (Tokyo) (2003) 0.96
Insect cytokine growth-blocking peptide triggers a termination system of cellular immunity by inducing its binding protein. J Biol Chem (2003) 0.96
A prodigiosin from the roseophilin producer Streptomyces griseoviridis. J Nat Prod (2008) 0.94
A eukaryotic (insect) tricistronic mRNA encodes three proteins selected by context-dependent scanning. J Biol Chem (2010) 0.94
Novel in vitro protein fragment complementation assay applicable to high-throughput screening in a 1536-well format. J Biomol Screen (2009) 0.94
Presence of copalyl diphosphate synthase gene in an actinomycete possessing the mevalonate pathway. J Antibiot (Tokyo) (2004) 0.93
Structures of grixazone A and B, A-factor-dependent yellow pigments produced under phosphate depletion by Streptomyces griseus. J Antibiot (Tokyo) (2004) 0.92
Nerve growth factor attenuates 2-deoxy-d-glucose-triggered endoplasmic reticulum stress-mediated apoptosis via enhanced expression of GRP78. Neurosci Res (2009) 0.92
Terpenoids Produced by Actinomycetes: Napyradiomycins from Streptomyces antimycoticus NT17. J Nat Prod (2008) 0.91
Bacillus subtilis ypgA gene is fni, a nonessential gene encoding type 2 isopentenyl diphosphate isomerase. Biosci Biotechnol Biochem (2004) 0.91
Diversity of the early step of the futalosine pathway. Antimicrob Agents Chemother (2010) 0.91
Promomycin, a polyether promoting antibiotic production in Streptomyces spp. J Antibiot (Tokyo) (2010) 0.91
Studies on terpenoids produced by actinomycetes. 5-dimethylallylindole-3-carboxylic Acid and A80915G-8"-acid produced by marine-derived Streptomyces sp. MS239. J Antibiot (Tokyo) (2008) 0.90
Streptomyces tateyamensis sp. nov., Streptomyces marinus sp. nov. and Streptomyces haliclonae sp. nov., isolated from the marine sponge Haliclona sp. Int J Syst Evol Microbiol (2010) 0.90
Roasting process of coffee beans as studied by nuclear magnetic resonance: time course of changes in composition. J Agric Food Chem (2012) 0.90
Complex mixture analysis of organic compounds in green coffee bean extract by two-dimensional NMR spectroscopy. Magn Reson Chem (2010) 0.90
Cloning and heterologous expression of the thioviridamide biosynthesis gene cluster from Streptomyces olivoviridis. Appl Environ Microbiol (2013) 0.89
Glucose-deprived HT-29 human colon carcinoma cells are sensitive to verrucosidin as a GRP78 down-regulator. Toxicology (2006) 0.89
Structure of tyroscherin, an antitumor antibiotic against IGF-1-dependent cells from Pseudallescheria sp. J Antibiot (Tokyo) (2004) 0.89
Koshikamide B, a cytotoxic peptide lactone from a marine sponge Theonella sp. J Org Chem (2008) 0.89
Metabolic discrimination of mango juice from various cultivars by band-selective NMR spectroscopy. J Agric Food Chem (2012) 0.89
Distribution of the 3-hydroxyl-3-methylglutaryl coenzyme A reductase gene and isoprenoid production in marine-derived Actinobacteria. FEMS Microbiol Lett (2009) 0.89
Glycolytic intermediates induce amorphous calcium carbonate formation in crustaceans. Nat Chem Biol (2011) 0.88
Urukthapelstatin A, a novel cytotoxic substance from marine-derived Mechercharimyces asporophorigenens YM11-542. I. Fermentation, isolation and biological activities. J Antibiot (Tokyo) (2007) 0.88
Gracilioethers A-C, antimalarial metabolites from the marine sponge Agelas gracilis. J Org Chem (2009) 0.88
Prodigiosin biosynthesis gene cluster in the roseophilin producer Streptomyces griseoviridis. J Antibiot (Tokyo) (2009) 0.88
JBIR-83 and JBIR-84, new promothiocin derivatives, isolated from Streptomyces sp. RI19. J Antibiot (Tokyo) (2010) 0.88
Relative and absolute configuration of versipelostatin, a down-regulator of molecular chaperone GRP78 expression. Org Lett (2007) 0.87
Drosophila growth-blocking peptide-like factor mediates acute immune reactions during infectious and non-infectious stress. Sci Rep (2012) 0.86
Tetracenoquinocin and 5-iminoaranciamycin from a sponge-derived Streptomyces sp. Sp080513GE-26. J Nat Prod (2010) 0.86
Structures of two monomeric units of teichoic acid prepared from the cell wall of Lactobacillus plantarum NRIC 1068. Biosci Biotechnol Biochem (2009) 0.86
Peptide mimics of epidermal growth factor (EGF) with antagonistic activity. J Biotechnol (2005) 0.86
JBIR-31, a new teleocidin analog, produced by salt-requiring Streptomyces sp. NBRC 105896 isolated from a marine sponge. J Antibiot (Tokyo) (2009) 0.86
A novel peptide mediates aggregation and migration of hemocytes from an insect. Curr Biol (2009) 0.86
Structure of aspochalasin H, a new member of the aspochalasin family. J Antibiot (Tokyo) (2002) 0.85
Studies on terpenoids produced by actinomycetes: oxaloterpins A, B, C, D, and E, diterpenes from Streptomyces sp. KO-3988. J Nat Prod (2007) 0.85
Three new depsipeptides, JBIR-113, JBIR-114 and JBIR-115, isolated from a marine sponge-derived Penicillium sp. fS36. J Antibiot (Tokyo) (2011) 0.85
A cryptic antibiotic triggered by monensin. J Antibiot (Tokyo) (2011) 0.84
Oximidines I and II: Novel Antitumor Macrolides from Pseudomonas sp. J Org Chem (1999) 0.84
Mechanisms of black and white stripe pattern formation in the cuticles of insect larvae. J Insect Physiol (2006) 0.84
A gene involved in the food preferences of larval Drosophila melanogaster. J Insect Physiol (2008) 0.84
Adaptor protein is essential for insect cytokine signaling in hemocytes. Proc Natl Acad Sci U S A (2010) 0.84
Selective cytotoxic activity of valinomycin against HT-29 Human colon carcinoma cells via down-regulation of GRP78. Biol Pharm Bull (2006) 0.84
Insect cytokine, growth-blocking peptide, is a primary regulator of melanin-synthesis enzymes in armyworm larval cuticle. FEBS J (2007) 0.84
Nomimicin, a new spirotetronate-class polyketide from an actinomycete of the genus Actinomadura. J Antibiot (Tokyo) (2012) 0.84
Ammocidins B, C and D, new cytotoxic 20-membered macrolides from Saccharothrix sp. AJ9571. J Antibiot (Tokyo) (2009) 0.83
JBIR-22, an inhibitor for protein-protein interaction of the homodimer of proteasome assembly factor 3. J Nat Prod (2010) 0.83
Nondestructive observation of bovine milk by NMR spectroscopy: analysis of existing States of compounds and detection of new compounds. J Agric Food Chem (2004) 0.83
Prunustatin A, a novel GRP78 molecular chaperone down-regulator isolated from Streptomyces violaceoniger. J Antibiot (Tokyo) (2005) 0.83
Analysis of the biological activity of a novel 24-membered macrolide JBIR-19 in Saccharomyces cerevisiae by the morphological imaging program CalMorph. FEMS Yeast Res (2012) 0.83
Identification and biosynthesis of new acyloins from the thermophilic bacterium Thermosporothrix hazakensis SK20-1(T). Chembiochem (2014) 0.83
New tensidols, JBIR-86 and JBIR-87, isolated from Aspergillus sp. fJ80. J Antibiot (Tokyo) (2010) 0.82
Rhodococcus kyotonensis sp. nov., a novel actinomycete isolated from soil. Int J Syst Evol Microbiol (2007) 0.82
Expression and purification of a small cytokine growth-blocking peptide from armyworm Pseudaletia separata by an optimized fermentation method using the methylotrophic yeast Pichia pastoris. Protein Expr Purif (2002) 0.82
Absolute structure of prunustatin A, a novel GRP78 molecular chaperone down-regulator. Org Lett (2007) 0.82
Aogacillins A and B produced by Simplicillium sp. FKI-5985: new circumventors of arbekacin resistance in MRSA. Org Lett (2013) 0.82
Nondestructive quantification of organic compounds in whole milk without pretreatment by two-dimensional NMR spectroscopy. J Agric Food Chem (2007) 0.81
Two-dimensional 1H-13C nuclear magnetic resonance (NMR)-based comprehensive analysis of roasted coffee bean extract. J Agric Food Chem (2011) 0.81
Identification of a gene, Desiccate, contributing to desiccation resistance in Drosophila melanogaster. J Biol Chem (2010) 0.81
JBIR-52, a new antimycin-like compound, from Streptomyces sp. ML55. J Antibiot (Tokyo) (2009) 0.81
Etoposide-resistant HT-29 human colon carcinoma cells during glucose deprivation are sensitive to piericidin A, a GRP78 down-regulator. J Cell Physiol (2008) 0.81
Resistance to senescence induction and telomere shortening by a G-quadruplex ligand inhibitor of telomerase. Cancer Res (2003) 0.81
(13)C NMR-based metabolomics for the classification of green coffee beans according to variety and origin. J Agric Food Chem (2012) 0.81
Cause of mortality in insects under severe stress. Eur J Biochem (2003) 0.81
Solution structure of paralytic peptide of silkworm, Bombyx mori. Peptides (2002) 0.80
Venom components of Asobara japonica impair cellular immune responses of host Drosophila melanogaster. Arch Insect Biochem Physiol (2013) 0.80
Isolation of a novel macrocyclic dilactone-JBIR-101-from Promicromonospora sp. RL26. J Antibiot (Tokyo) (2011) 0.80
Enhanced expression of stress-responsive cytokine-like gene retards insect larval growth. Insect Biochem Mol Biol (2011) 0.80
A cytokine secreted from the suboesophageal body is essential for morphogenesis of the insect head. Mech Dev (2005) 0.80
Isolation and tyrosinase inhibitory effects of polyphenols from the leaves of persimmon, Diospyros kaki. J Agric Food Chem (2011) 0.80
Relative and absolute stereochemistry of quinadoline B, an inhibitor of lipid droplet synthesis in macrophages. Org Lett (2008) 0.79
A novel versipelostatin analogue, versipelostatin F isolated from Streptomyces versipellis 4083-SVS6. J Antibiot (Tokyo) (2008) 0.79
Analysis of hunger-driven gene expression in the Drosophila melanogaster larval central nervous system. Zoolog Sci (2008) 0.79
Legioliulin, a new isocoumarin compound responsible for blue-white autofluorescence in Legionella (Fluoribacter) dumoffii under long-wavelength UV light. Biochem Biophys Res Commun (2004) 0.79