Transcriptional regulation of human small nuclear RNA genes.

Defining the RNA polymerase III transcriptome: Genome-wide localization of the RNA polymerase III transcription machinery in human cells. Genome Res (2010) 1.57

Chromatin structure is implicated in "late" elongation checkpoints on the U2 snRNA and beta-actin genes. Mol Cell Biol (2009) 1.23

Genomic study of RNA polymerase II and III SNAPc-bound promoters reveals a gene transcribed by both enzymes and a broad use of common activators. PLoS Genet (2012) 1.06

The little elongation complex regulates small nuclear RNA transcription. Mol Cell (2011) 1.06

Fast homozygosity mapping and identification of a zebrafish ENU-induced mutation by whole-genome sequencing. PLoS One (2012) 1.04

ATAC and Mediator coactivators form a stable complex and regulate a set of non-coding RNA genes. EMBO Rep (2010) 1.00

Negative regulation of human U6 snRNA promoter by p38 kinase through Oct-1. Gene (2012) 0.99

Promoter-proximal polyadenylation sites reduce transcription activity. Genes Dev (2012) 0.98

Identification of SNAPc subunit domains that interact with specific nucleotide positions in the U1 and U6 gene promoters. Mol Cell Biol (2010) 0.93

Regulation of human RNA polymerase III transcription by DNMT1 and DNMT3a DNA methyltransferases. J Biol Chem (2012) 0.90

RNA polymerase III repression by the retinoblastoma tumor suppressor protein. Biochim Biophys Acta (2012) 0.89

Gene duplication and neofunctionalization: POLR3G and POLR3GL. Genome Res (2013) 0.87

The little elongation complex functions at initiation and elongation phases of snRNA gene transcription. Mol Cell (2013) 0.86

Integrator: surprisingly diverse functions in gene expression. Trends Biochem Sci (2015) 0.86

Non-mRNA 3' end formation: how the other half lives. Wiley Interdiscip Rev RNA (2013) 0.84

Genome-wide evolutionary analysis of the noncoding RNA genes and noncoding DNA of Paramecium tetraurelia. RNA (2009) 0.83

Human U2 snRNA genes exhibit a persistently open transcriptional state and promoter disassembly at metaphase. Mol Cell Biol (2008) 0.83

A role for the Cajal-body-associated SUMO isopeptidase USPL1 in snRNA transcription mediated by RNA polymerase II. J Cell Sci (2014) 0.82

Differential utilization of TATA box-binding protein (TBP) and TBP-related factor 1 (TRF1) at different classes of RNA polymerase III promoters. J Biol Chem (2013) 0.82

From Glacier to Sauna: RNA-Seq of the Human Pathogen Black Fungus Exophiala dermatitidis under Varying Temperature Conditions Exhibits Common and Novel Fungal Response. PLoS One (2015) 0.81

Mutation of zebrafish Snapc4 is associated with loss of the intrahepatic biliary network. Dev Biol (2011) 0.80

tRNASec is transcribed by RNA polymerase II in Trypanosoma brucei but not in humans. Nucleic Acids Res (2010) 0.80

Transcriptional regulation of snRNAs and its significance for plant development. J Plant Res (2016) 0.79

The C. elegans SNAPc component SNPC-4 coats piRNA domains and is globally required for piRNA abundance. Dev Cell (2014) 0.78

A membrane-type-1 matrix metalloproteinase (MT1-MMP)-discoidin domain receptor 1 axis regulates collagen-induced apoptosis in breast cancer cells. PLoS One (2015) 0.78

Human RNase P ribonucleoprotein is required for formation of initiation complexes of RNA polymerase III. Nucleic Acids Res (2015) 0.76

MED26 regulates the transcription of snRNA genes through the recruitment of little elongation complex. Nat Commun (2015) 0.76

The Myb domain of the largest subunit of SNAPc adopts different architectural configurations on U1 and U6 snRNA gene promoter sequences. Nucleic Acids Res (2014) 0.75

The 7SK snRNP associates with the little elongation complex to promote snRNA gene expression. EMBO J (2017) 0.75

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature (2007) 75.09

Retinoblastoma protein recruits histone deacetylase to repress transcription. Nature (1998) 8.75

The role of small nuclear ribonucleoprotein particles in pre-mRNA splicing. Nature (1987) 8.28

Splicing of messenger RNA precursors. Science (1987) 7.61

Rb interacts with histone deacetylase to repress transcription. Cell (1998) 7.22

Retinoblastoma protein represses transcription by recruiting a histone deacetylase. Nature (1998) 6.87

RNA polymerase III transcribes human microRNAs. Nat Struct Mol Biol (2006) 6.81

Two novel classes of small ribonucleoproteins detected by antibodies associated with lupus erythematosus. Science (1981) 6.34

Spliceosomal RNA U6 is remarkably conserved from yeast to mammals. Nature (1988) 5.48

Retinoblastoma protein switches the E2F site from positive to negative element. Nature (1992) 5.47

Making ribosomes. Curr Opin Cell Biol (2002) 5.20

The 7SK small nuclear RNA inhibits the CDK9/cyclin T1 kinase to control transcription. Nature (2001) 5.14

7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexes. Nature (2001) 5.11

90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors. Mol Cell (2002) 4.78

Identification of a growth suppression domain within the retinoblastoma gene product. Genes Dev (1992) 4.56

Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF. Cell (2000) 4.48

Recruitment of RNA polymerase III to its target promoters. Genes Dev (2002) 4.36

Crystal structure of the Oct-1 POU domain bound to an octamer site: DNA recognition with tethered DNA-binding modules. Cell (1994) 3.98

Survey and summary: transcription by RNA polymerases I and III. Nucleic Acids Res (2000) 3.71

Formation of the 3' end of U1 snRNA requires compatible snRNA promoter elements. Cell (1986) 3.69

Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II. Cell (2005) 3.66

Serine-7 of the RNA polymerase II CTD is specifically required for snRNA gene expression. Science (2007) 3.36

Direct activation of RNA polymerase III transcription by c-Myc. Nature (2003) 3.32

A 7 bp mutation converts a human RNA polymerase II snRNA promoter into an RNA polymerase III promoter. Cell (1989) 3.28

U1 snRNA associates with TFIIH and regulates transcriptional initiation. Nat Struct Biol (2002) 3.25

Identification and characterization of an RNA molecule that copurifies with RNase P activity from HeLa cells. Genes Dev (1989) 3.16

U6 small nuclear RNA is transcribed by RNA polymerase III. Proc Natl Acad Sci U S A (1986) 3.14

Repression of RNA polymerase III transcription by the retinoblastoma protein. Nature (1996) 3.04

A common octamer motif binding protein is involved in the transcription of U6 snRNA by RNA polymerase III and U2 snRNA by RNA polymerase II. Cell (1987) 2.99

Changing the RNA polymerase specificity of U snRNA gene promoters. Cell (1988) 2.85

Mechanism of transcription through the nucleosome by eukaryotic RNA polymerase. Science (1997) 2.81

RNA polymerases I and III, growth control and cancer. Nat Rev Mol Cell Biol (2005) 2.77

Stimulatory effect of splicing factors on transcriptional elongation. Nature (2002) 2.76

Formation of the 3' end of U1 snRNA is directed by a conserved sequence located downstream of the coding region. EMBO J (1985) 2.69

The RNA of RNase MRP is required for normal processing of ribosomal RNA. Proc Natl Acad Sci U S A (1994) 2.68

Mammalian microRNAs: a small world for fine-tuning gene expression. Mamm Genome (2006) 2.64

Retinoblastoma protein partners. Adv Cancer Res (2001) 2.53

Human genes for U2 small nuclear RNA are tandemly repeated. Mol Cell Biol (1984) 2.52

Human U1 loci: genes for human U1 RNA have dramatically similar genomic environments. Cell (1982) 2.51

Oct-1 and Oct-2 potentiate functional interactions of a transcription factor with the proximal sequence element of small nuclear RNA genes. Mol Cell Biol (1992) 2.47

p53 modulation of TFIIH-associated nucleotide excision repair activity. Nat Genet (1995) 2.47

Structural insights into RNA quality control: the Ro autoantigen binds misfolded RNAs via its central cavity. Cell (2005) 2.40

True genes for human U1 small nuclear RNA. Copy number, polymorphism, and methylation. J Biol Chem (1984) 2.35

Proximal sequence element-binding transcription factor (PTF) is a multisubunit complex required for transcription of both RNA polymerase II- and RNA polymerase III-dependent small nuclear RNA genes. Mol Cell Biol (1995) 2.33

A role for the yeast La protein in U6 snRNP assembly: evidence that the La protein is a molecular chaperone for RNA polymerase III transcripts. EMBO J (1998) 2.31

Targeting TBP to a non-TATA box cis-regulatory element: a TBP-containing complex activates transcription from snRNA promoters through the PSE. Genes Dev (1993) 2.27

A TBP-TAF complex required for transcription of human snRNA genes by RNA polymerase II and III. Nature (1995) 2.20

Induction of specific chromosomal aberrations by adenovirus type 12 in human embryonic kidney cells. J Virol (1967) 2.20

Structure and transcription of a human gene for H1 RNA, the RNA component of human RNase P. Nucleic Acids Res (1990) 2.18

RNA polymerase III transcription and cancer. Oncogene (2004) 2.13

Association of human TFIID-promoter complexes with silenced mitotic chromatin in vivo. Nat Cell Biol (2002) 2.10

Human U2 and U1 RNA genes use similar transcription signals. EMBO J (1984) 2.01

Elements required for transcription initiation of the human U2 snRNA gene coincide with elements required for snRNA 3' end formation. EMBO J (1988) 1.97

Identification of transcription factors required for the expression of mammalian U6 genes in vitro. EMBO J (1991) 1.95

CSB is a component of RNA pol I transcription. Mol Cell (2002) 1.93

Distinct factors with Sp1 and NF-A specificities bind to adjacent functional elements of the human U2 snRNA gene enhancer. Genes Dev (1987) 1.85

A role for beta-actin in RNA polymerase III transcription. Genes Dev (2004) 1.82

RNase MRP cleaves the CLB2 mRNA to promote cell cycle progression: novel method of mRNA degradation. Mol Cell Biol (2004) 1.81

Identification of novel functional TBP-binding sites and general factor repertoires. EMBO J (2007) 1.77

Mitotic repression of RNA polymerase III transcription in vitro mediated by phosphorylation of a TFIIIB component. Science (1994) 1.75

Protein kinase A regulates RNA polymerase III transcription through the nuclear localization of Maf1. Proc Natl Acad Sci U S A (2006) 1.74

Vaults are up-regulated in multidrug-resistant cancer cell lines. J Biol Chem (1998) 1.74

p53 is a general repressor of RNA polymerase III transcription. EMBO J (1998) 1.72

Cloning of two proximal sequence element-binding transcription factor subunits (gamma and delta) that are required for transcription of small nuclear RNA genes by RNA polymerases II and III and interact with the TATA-binding protein. Mol Cell Biol (1996) 1.70

Mechanism of transcriptional repression of E2F by the retinoblastoma tumor suppressor protein. Mol Cell (1999) 1.69

Basal promoter elements as a selective determinant of transcriptional activator function. Nature (1995) 1.69

p53 represses RNA polymerase III transcription by targeting TBP and inhibiting promoter occupancy by TFIIIB. EMBO J (2003) 1.68

Different human TFIIIB activities direct RNA polymerase III transcription from TATA-containing and TATA-less promoters. Genes Dev (2000) 1.61

Characterization of a multisubunit transcription factor complex essential for spliced-leader RNA gene transcription in Trypanosoma brucei. Mol Cell Biol (2005) 1.59

Two steps in Maf1-dependent repression of transcription by RNA polymerase III. J Biol Chem (2004) 1.58

Maf1, a new player in the regulation of human RNA polymerase III transcription. PLoS One (2006) 1.54

Multiple cis-acting elements are required for RNA polymerase III transcription of the gene encoding H1 RNA, the RNA component of human RNase P. J Biol Chem (1991) 1.52

The large subunit of basal transcription factor SNAPc is a Myb domain protein that interacts with Oct-1. Mol Cell Biol (1998) 1.50

Metabolism of small molecular weight monodisperse nuclear RNA. Biochim Biophys Acta (1969) 1.47

Activation of p53 or loss of the Cockayne syndrome group B repair protein causes metaphase fragility of human U1, U2, and 5S genes. Mol Cell (2000) 1.46

Cell cycle regulation of RNA polymerase III transcription. Mol Cell Biol (1995) 1.44

Characterization of human MRP/Th RNA and its nuclear gene: full length MRP/Th RNA is an active endoribonuclease when assembled as an RNP. Nucleic Acids Res (1990) 1.42

Mechanistic analysis of RNA polymerase III regulation by the retinoblastoma protein. EMBO J (1997) 1.41

The SNAP45 subunit of the small nuclear RNA (snRNA) activating protein complex is required for RNA polymerase II and III snRNA gene transcription and interacts with the TATA box binding protein. Proc Natl Acad Sci U S A (1996) 1.41

Cloning and characterization of SNAP50, a subunit of the snRNA-activating protein complex SNAPc. EMBO J (1996) 1.40

Vaults: a ribonucleoprotein particle involved in drug resistance? Oncogene (2003) 1.39

TFIIIB is phosphorylated, disrupted and selectively released from tRNA promoters during mitosis in vivo. EMBO J (2003) 1.36

Role for the amino-terminal region of human TBP in U6 snRNA transcription. Science (1997) 1.36

A nucleosome positioned in the distal promoter region activates transcription of the human U6 gene. Mol Cell Biol (1997) 1.35

Trypanosomal TBP functions with the multisubunit transcription factor tSNAP to direct spliced-leader RNA gene expression. Mol Cell Biol (2005) 1.35

The Saccharomyces cerevisiae RNase mitochondrial RNA processing is critical for cell cycle progression at the end of mitosis. Genetics (2002) 1.34

Retinoblastoma protein disrupts interactions required for RNA polymerase III transcription. Mol Cell Biol (2000) 1.34

The Ro autoantigen binds misfolded U2 small nuclear RNAs and assists mammalian cell survival after UV irradiation. Curr Biol (2003) 1.32

SNAP19 mediates the assembly of a functional core promoter complex (SNAPc) shared by RNA polymerases II and III. Genes Dev (1998) 1.31

Functional requirement of noncoding Y RNAs for human chromosomal DNA replication. Mol Cell Biol (2006) 1.31

Human genes for U2 small nuclear RNA map to a major adenovirus 12 modification site on chromosome 17. Nature (1985) 1.30

Chromatin remodeling and Rb activity. Curr Opin Cell Biol (2000) 1.30

Staf, a promiscuous activator for enhanced transcription by RNA polymerases II and III. EMBO J (1997) 1.29

Human U1 small nuclear RNA genes: extensive conservation of flanking sequences suggests cycles of gene amplification and transposition. Mol Cell Biol (1985) 1.27

A role for RNAase MRP in mitochondrial RNA processing. Cell (1992) 1.27

A misfolded form of 5S rRNA is complexed with the Ro and La autoantigens. RNA (1996) 1.27

Repression of RNA polymerase II and III transcription during M phase of the cell cycle. Exp Cell Res (1996) 1.26

A stable complex of a novel transcription factor IIB- related factor, human TFIIIB50, and associated proteins mediate selective transcription by RNA polymerase III of genes with upstream promoter elements. Proc Natl Acad Sci U S A (2000) 1.26

ZNF76 and ZNF143 are two human homologs of the transcriptional activator Staf. J Biol Chem (1998) 1.26

p53 inhibits RNA polymerase III-directed transcription in a promoter-dependent manner. Mol Cell Biol (1996) 1.26

TBP dynamics in living human cells: constitutive association of TBP with mitotic chromosomes. Mol Biol Cell (2002) 1.78

Distinct mechanisms for repression of RNA polymerase III transcription by the retinoblastoma tumor suppressor protein. Mol Cell Biol (2004) 1.13

High-impact conservation: invasive mammal eradications from the islands of western México. Ambio (2008) 1.13

Brg1 is required for Cdx2-mediated repression of Oct4 expression in mouse blastocysts. PLoS One (2010) 1.11

The p53 tumor suppressor protein represses human snRNA gene transcription by RNA polymerases II and III independently of sequence-specific DNA binding. Mol Cell Biol (2005) 1.10

Retinoblastoma protein regulation by the COP9 signalosome. Mol Biol Cell (2007) 1.02

The perinucleolar compartment is directly associated with DNA. J Biol Chem (2008) 0.96

The small nuclear RNA-activating protein 190 Myb DNA binding domain stimulates TATA box-binding protein-TATA box recognition. J Biol Chem (2003) 0.96

The unorthodox SNAP50 zinc finger domain contributes to cooperative promoter recognition by human SNAPC. J Biol Chem (2006) 0.90

Regulation of human RNA polymerase III transcription by DNMT1 and DNMT3a DNA methyltransferases. J Biol Chem (2012) 0.90

RNA polymerase III repression by the retinoblastoma tumor suppressor protein. Biochim Biophys Acta (2012) 0.89

Distinct developmental expression of Drosophila retinoblastoma factors. Gene Expr Patterns (2005) 0.89

Evidence for autoregulation and cell signaling pathway regulation from genome-wide binding of the Drosophila retinoblastoma protein. G3 (Bethesda) (2012) 0.86

Paradoxical instability-activity relationship defines a novel regulatory pathway for retinoblastoma proteins. Mol Biol Cell (2010) 0.85

Nuclear factor-kappaB mediated inhibition of cytokine production by imidazoline scaffolds. J Med Chem (2009) 0.85

Ubiquitination of retinoblastoma family protein 1 potentiates gene-specific repression function. J Biol Chem (2012) 0.82

Radioprotection by hymenialdisine-derived checkpoint kinase 2 inhibitors. ACS Chem Biol (2011) 0.82

Activator recruitment by the general transcription machinery: X-ray structural analysis of the Oct-1 POU domain/human U1 octamer/SNAP190 peptide ternary complex. Genes Dev (2002) 0.81

Co-expression of multiple subunits enables recombinant SNAPC assembly and function for transcription by human RNA polymerases II and III. Protein Expr Purif (2006) 0.81

The protein kinase CK2 phosphorylates SNAP190 to negatively regulate SNAPC DNA binding and human U6 transcription by RNA polymerase III. J Biol Chem (2007) 0.81

Noncompetitive modulation of the proteasome by imidazoline scaffolds overcomes bortezomib resistance and delays MM tumor growth in vivo. ACS Chem Biol (2012) 0.80

Rbf1 degron dysfunction enhances cellular DNA replication. Cell Cycle (2012) 0.80

Attenuation of collagen-induced arthritis by orally available imidazoline-based NF-κB inhibitors. Bioorg Med Chem Lett (2012) 0.78

Role of Drosophila retinoblastoma protein instability element in cell growth and proliferation. Cell Cycle (2015) 0.78

Cooperation between small nuclear RNA-activating protein complex (SNAPC) and TATA-box-binding protein antagonizes protein kinase CK2 inhibition of DNA binding by SNAPC. J Biol Chem (2005) 0.78

Reprint of BMCL_19101. Bioorg Med Chem Lett (2012) 0.75