Published in Proc Natl Acad Sci U S A on June 12, 2006
The exosome contains domains with specific endoribonuclease, exoribonuclease and cytoplasmic mRNA decay activities. Nat Struct Mol Biol (2008) 2.81
Ribosome biogenesis in the yeast Saccharomyces cerevisiae. Genetics (2013) 2.70
Toward a comprehensive temperature-sensitive mutant repository of the essential genes of Saccharomyces cerevisiae. Mol Cell (2008) 2.39
Powering through ribosome assembly. RNA (2009) 2.19
When ribosomes go bad: diseases of ribosome biogenesis. Mol Biosyst (2010) 1.76
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Nob1 binds the single-stranded cleavage site D at the 3'-end of 18S rRNA with its PIN domain. Proc Natl Acad Sci U S A (2009) 1.53
A direct interaction between the Utp6 half-a-tetratricopeptide repeat domain and a specific peptide in Utp21 is essential for efficient pre-rRNA processing. Mol Cell Biol (2008) 1.30
The initial U3 snoRNA:pre-rRNA base pairing interaction required for pre-18S rRNA folding revealed by in vivo chemical probing. Nucleic Acids Res (2011) 1.23
Novel endoribonucleases as central players in various pathways of eukaryotic RNA metabolism. RNA (2010) 1.20
An endoribonuclease functionally linked to perinuclear mRNP quality control associates with the nuclear pore complexes. PLoS Biol (2009) 1.10
The DEAD-box RNA helicase-like Utp25 is an SSU processome component. RNA (2010) 1.04
Rcl1 protein, a novel nuclease for 18 S ribosomal RNA production. J Biol Chem (2011) 0.99
Mrd1p binds to pre-rRNA early during transcription independent of U3 snoRNA and is required for compaction of the pre-rRNA into small subunit processomes. Nucleic Acids Res (2008) 0.96
Stepwise and dynamic assembly of the earliest precursors of small ribosomal subunits in yeast. Genes Dev (2016) 0.92
An RNA-binding complex involved in ribosome biogenesis contains a protein with homology to tRNA CCA-adding enzyme. PLoS Biol (2013) 0.90
Nuclear export competence of pre-40S subunits in fission yeast requires the ribosomal protein Rps2. Nucleic Acids Res (2008) 0.88
Utp23p is required for dissociation of snR30 small nucleolar RNP from preribosomal particles. Nucleic Acids Res (2011) 0.87
Two orthogonal cleavages separate subunit RNAs in mouse ribosome biogenesis. Nucleic Acids Res (2014) 0.87
Structural and functional analysis of Utp23, a yeast ribosome synthesis factor with degenerate PIN domain. RNA (2013) 0.83
hUTP24 is essential for processing of the human rRNA precursor at site A1, but not at site A0. RNA Biol (2015) 0.81
atBRX1-1 and atBRX1-2 are involved in an alternative rRNA processing pathway in Arabidopsis thaliana. RNA (2015) 0.79
RNA stability: is it the endo' the world as we know it? Nat Struct Mol Biol (2009) 0.79
The PIN domain endonuclease Utp24 cleaves pre-ribosomal RNA at two coupled sites in yeast and humans. Nucleic Acids Res (2016) 0.79
Molecular architecture of the 90S small subunit pre-ribosome. Elife (2017) 0.78
Analysis of non-typeable Haemophilous influenzae VapC1 mutations reveals structural features required for toxicity and flexibility in the active site. PLoS One (2014) 0.77
Yeast hEST1A/B (SMG5/6)-like proteins contribute to environment-sensing adaptive gene expression responses. G3 (Bethesda) (2013) 0.77
Colorectal cancer risk variants at 8q23.3 and 11q23.1 are associated with disease phenotype in APC mutation carriers. Fam Cancer (2016) 0.76
A PilT N-terminus domain protein SSO1118 from hyperthemophilic archaeon Sulfolobus solfataricus P2. J Biomol NMR (2013) 0.76
"PP2C7s", Genes Most Highly Elaborated in Photosynthetic Organisms, Reveal the Bacterial Origin and Stepwise Evolution of PPM/PP2C Protein Phosphatases. PLoS One (2015) 0.75
The ribosome biogenesis factor yUtp23/hUTP23 coordinates key interactions in the yeast and human pre-40S particle and hUTP23 contains an essential PIN domain. Nucleic Acids Res (2017) 0.75
Structural conservation of the PIN domain active site across all domains of life. Protein Sci (2017) 0.75
Comprehensive classification of the PIN domain-like superfamily. Nucleic Acids Res (2017) 0.75
Functional organization of the yeast proteome by systematic analysis of protein complexes. Nature (2002) 45.19
Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature (2002) 37.66
Functional profiling of the Saccharomyces cerevisiae genome. Nature (2002) 36.10
Global analysis of protein localization in budding yeast. Nature (2003) 33.22
Proteome survey reveals modularity of the yeast cell machinery. Nature (2006) 20.77
The exosome: a conserved eukaryotic RNA processing complex containing multiple 3'-->5' exoribonucleases. Cell (1997) 8.94
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A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis. Nature (2002) 6.19
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90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors. Mol Cell (2002) 4.78
Large-scale prediction of Saccharomyces cerevisiae gene function using overlapping transcriptional clusters. Nat Genet (2002) 4.68
High-definition macromolecular composition of yeast RNA-processing complexes. Mol Cell (2004) 4.18
The path from nucleolar 90S to cytoplasmic 40S pre-ribosomes. EMBO J (2003) 3.38
Pre-18S ribosomal RNA is structurally compacted into the SSU processome prior to being cleaved from nascent transcripts in Saccharomyces cerevisiae. Mol Cell (2004) 2.81
Predicting protein functions from redundancies in large-scale protein interaction networks. Proc Natl Acad Sci U S A (2003) 2.63
PIN domains in nonsense-mediated mRNA decay and RNAi. Curr Biol (2001) 2.26
Mpp10p, a U3 small nucleolar ribonucleoprotein component required for pre-18S rRNA processing in yeast. Mol Cell Biol (1997) 2.17
Imp3p and Imp4p, two specific components of the U3 small nucleolar ribonucleoprotein that are essential for pre-18S rRNA processing. Mol Cell Biol (1999) 2.06
Nob1p is required for cleavage of the 3' end of 18S rRNA. Mol Cell Biol (2003) 1.99
PIN domain of Nob1p is required for D-site cleavage in 20S pre-rRNA. RNA (2004) 1.94
Identification of residues in the Mu transposase essential for catalysis. Proc Natl Acad Sci U S A (1994) 1.94
The small-subunit processome is a ribosome assembly intermediate. Eukaryot Cell (2004) 1.84
The splicing ATPase prp43p is a component of multiple preribosomal particles. Mol Cell Biol (2005) 1.82
Distant structural homology leads to the functional characterization of an archaeal PIN domain as an exonuclease. J Biol Chem (2004) 1.74
The splicing factor Prp43p, a DEAH box ATPase, functions in ribosome biogenesis. Mol Cell Biol (2006) 1.70
Prp43p is a DEAH-box spliceosome disassembly factor essential for ribosome biogenesis. Mol Cell Biol (2006) 1.64
The sigma(70)-like motif: a eukaryotic RNA binding domain unique to a superfamily of proteins required for ribosome biogenesis. Mol Cell (2002) 1.53
Components of an interdependent unit within the SSU processome regulate and mediate its activity. Mol Cell Biol (2002) 1.45
A nucleolar protein related to ribosomal protein L7 is required for an early step in large ribosomal subunit biogenesis. Proc Natl Acad Sci U S A (2000) 1.33
Structure-specific DNA cleavage by 5' nucleases. Trends Biochem Sci (1998) 1.10
Mrd1p is required for processing of pre-rRNA and for maintenance of steady-state levels of 40 S ribosomal subunits in yeast. J Biol Chem (2002) 1.06
Esf2p, a U3-associated factor required for small-subunit processome assembly and compaction. Mol Cell Biol (2005) 1.04
ESF1 is required for 18S rRNA synthesis in Saccharomyces cerevisiae. Nucleic Acids Res (2004) 0.87
A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis. Nature (2002) 6.19
In exponentially growing Saccharomyces cerevisiae cells, rRNA synthesis is determined by the summed RNA polymerase I loading rate rather than by the number of active genes. Mol Cell Biol (2003) 2.88
Pre-18S ribosomal RNA is structurally compacted into the SSU processome prior to being cleaved from nascent transcripts in Saccharomyces cerevisiae. Mol Cell (2004) 2.81
Ribosome biogenesis in the yeast Saccharomyces cerevisiae. Genetics (2013) 2.70
Ribosome biogenesis: of knobs and RNA processing. Exp Cell Res (2004) 2.70
RNA polymerase I transcription and pre-rRNA processing are linked by specific SSU processome components. Genes Dev (2004) 2.48
Loss of Topoisomerase I leads to R-loop-mediated transcriptional blocks during ribosomal RNA synthesis. Genes Dev (2010) 2.44
Prp43 bound at different sites on the pre-rRNA performs distinct functions in ribosome synthesis. Mol Cell (2009) 2.36
The nuclear RNA polymerase II surveillance system targets polymerase III transcripts. EMBO J (2011) 1.99
The long unwinding road of RNA helicases. Mol Cell (2007) 1.97
Tor pathway regulates Rrn3p-dependent recruitment of yeast RNA polymerase I to the promoter but does not participate in alteration of the number of active genes. Mol Biol Cell (2003) 1.89
Cross-linking, ligation, and sequencing of hybrids reveals RNA-RNA interactions in yeast. Proc Natl Acad Sci U S A (2011) 1.85
The small-subunit processome is a ribosome assembly intermediate. Eukaryot Cell (2004) 1.84
RPD3 is required for the inactivation of yeast ribosomal DNA genes in stationary phase. EMBO J (2002) 1.79
When ribosomes go bad: diseases of ribosome biogenesis. Mol Biosyst (2010) 1.76
The small subunit processome in ribosome biogenesis—progress and prospects. Wiley Interdiscip Rev RNA (2011) 1.66
Proofreading of pre-40S ribosome maturation by a translation initiation factor and 60S subunits. Nat Struct Mol Biol (2012) 1.62
Transcription elongation by RNA polymerase I is linked to efficient rRNA processing and ribosome assembly. Mol Cell (2007) 1.59
The sigma(70)-like motif: a eukaryotic RNA binding domain unique to a superfamily of proteins required for ribosome biogenesis. Mol Cell (2002) 1.53
The putative NTPase Fap7 mediates cytoplasmic 20S pre-rRNA processing through a direct interaction with Rps14. Mol Cell Biol (2005) 1.46
Components of an interdependent unit within the SSU processome regulate and mediate its activity. Mol Cell Biol (2002) 1.45
Genetics. Mysterious ribosomopathies. Science (2013) 1.44
Ribosome biogenesis is sensed at the Start cell cycle checkpoint. Mol Biol Cell (2006) 1.43
The human Imp3 and Imp4 proteins form a ternary complex with hMpp10, which only interacts with the U3 snoRNA in 60-80S ribonucleoprotein complexes. Nucleic Acids Res (2003) 1.41
Sch9 regulates ribosome biogenesis via Stb3, Dot6 and Tod6 and the histone deacetylase complex RPD3L. EMBO J (2011) 1.40
Crosstalk in gene expression: coupling and co-regulation of rDNA transcription, pre-ribosome assembly and pre-rRNA processing. Curr Opin Cell Biol (2005) 1.35
Structure of the pre-60S ribosomal subunit with nuclear export factor Arx1 bound at the exit tunnel. Nat Struct Mol Biol (2012) 1.34
A direct interaction between the Utp6 half-a-tetratricopeptide repeat domain and a specific peptide in Utp21 is essential for efficient pre-rRNA processing. Mol Cell Biol (2008) 1.30
PAR-CLIP data indicate that Nrd1-Nab3-dependent transcription termination regulates expression of hundreds of protein coding genes in yeast. Genome Biol (2014) 1.30
The small subunit processome is required for cell cycle progression at G1. Mol Biol Cell (2004) 1.26
The initial U3 snoRNA:pre-rRNA base pairing interaction required for pre-18S rRNA folding revealed by in vivo chemical probing. Nucleic Acids Res (2011) 1.23
Distinguishing the roles of Topoisomerases I and II in relief of transcription-induced torsional stress in yeast rRNA genes. Mol Cell Biol (2010) 1.21
Transcriptional termination by RNA polymerase I requires the small subunit Rpa12p. Proc Natl Acad Sci U S A (2004) 1.20
The Paf1 complex is required for efficient transcription elongation by RNA polymerase I. Proc Natl Acad Sci U S A (2009) 1.16
Comprehensive mutational analysis of yeast DEXD/H box RNA helicases involved in large ribosomal subunit biogenesis. Mol Cell Biol (2006) 1.15
A dimeric structure for archaeal box C/D small ribonucleoproteins. Science (2009) 1.14
The nucleolar protein Esf2 interacts directly with the DExD/H box RNA helicase, Dbp8, to stimulate ATP hydrolysis. Nucleic Acids Res (2006) 1.13
Comprehensive mutational analysis of yeast DEXD/H box RNA helicases required for small ribosomal subunit synthesis. Mol Cell Biol (2006) 1.11
Transcription and translation are coupled in Archaea. Mol Biol Evol (2007) 1.10
The C-terminus of Utp4, mutated in childhood cirrhosis, is essential for ribosome biogenesis. Nucleic Acids Res (2010) 1.10
NOL11, implicated in the pathogenesis of North American Indian childhood cirrhosis, is required for pre-rRNA transcription and processing. PLoS Genet (2012) 1.07
Delayed rRNA processing results in significant ribosome biogenesis and functional defects. Mol Cell Biol (2003) 1.05
The DEAD-box RNA helicase-like Utp25 is an SSU processome component. RNA (2010) 1.04
Esf2p, a U3-associated factor required for small-subunit processome assembly and compaction. Mol Cell Biol (2005) 1.04
Electron microscope visualization of RNA transcription and processing in Saccharomyces cerevisiae by Miller chromatin spreading. Methods Mol Biol (2009) 1.02
Box C/D snoRNP catalysed methylation is aided by additional pre-rRNA base-pairing. EMBO J (2011) 1.02
Spliceosome-mediated decay (SMD) regulates expression of nonintronic genes in budding yeast. Genes Dev (2013) 1.00
EM visualization of Pol II genes in Drosophila: most genes terminate without prior 3' end cleavage of nascent transcripts. Chromosoma (2002) 0.99
Adenovirus protein VII condenses DNA, represses transcription, and associates with transcriptional activator E1A. J Virol (2004) 0.98
Mrd1p binds to pre-rRNA early during transcription independent of U3 snoRNA and is required for compaction of the pre-rRNA into small subunit processomes. Nucleic Acids Res (2008) 0.96
Role of histone deacetylase Rpd3 in regulating rRNA gene transcription and nucleolar structure in yeast. Mol Cell Biol (2006) 0.92
Multiple RNA interactions position Mrd1 at the site of the small subunit pseudoknot within the 90S pre-ribosome. Nucleic Acids Res (2012) 0.92
A conserved deubiquitinating enzyme controls cell growth by regulating RNA polymerase I stability. Cell Rep (2012) 0.92
Transcription of multiple yeast ribosomal DNA genes requires targeting of UAF to the promoter by Uaf30. Mol Cell Biol (2008) 0.91
The transcription elongation factor Spt5 influences transcription by RNA polymerase I positively and negatively. J Biol Chem (2011) 0.91
Assembling a protein-protein interaction map of the SSU processome from existing datasets. PLoS One (2011) 0.90
Histones are required for transcription of yeast rRNA genes by RNA polymerase I. Proc Natl Acad Sci U S A (2005) 0.90
Visual analysis of the yeast 5S rRNA gene transcriptome: regulation and role of La protein. Mol Cell Biol (2008) 0.90
Identification of RNA helicase target sites by UV cross-linking and analysis of cDNA. Methods Enzymol (2012) 0.89
The box C/D sRNP dimeric architecture is conserved across domain Archaea. RNA (2012) 0.89
Divergent contributions of conserved active site residues to transcription by eukaryotic RNA polymerases I and II. Cell Rep (2013) 0.88
Two-hybrid Mpp10p interaction-defective Imp4 proteins are not interaction defective in vivo but do confer specific pre-rRNA processing defects in Saccharomyces cerevisiae. Nucleic Acids Res (2004) 0.86
Cohesion promotes nucleolar structure and function. Mol Biol Cell (2013) 0.85
A structural model for the HAT domain of Utp6 incorporating bioinformatics and genetics. Protein Eng Des Sel (2009) 0.84
The SWI/SNF chromatin remodeling complex influences transcription by RNA polymerase I in Saccharomyces cerevisiae. PLoS One (2013) 0.84
Identification of novel proteins associated with yeast snR30 small nucleolar RNA. Nucleic Acids Res (2011) 0.83
Dissecting the role of conserved box C/D sRNA sequences in di-sRNP assembly and function. Nucleic Acids Res (2010) 0.82
Mrd1p is required for release of base-paired U3 snoRNA within the preribosomal complex. Mol Cell Biol (2009) 0.82
Survival motor neuron protein in the nucleolus of mammalian neurons. Brain Res (2002) 0.81
Probing the yeast proteome for RNA-processing factors. Genome Biol (2003) 0.81
Regulation of rRNA synthesis by TATA-binding protein-associated factor Mot1. Mol Cell Biol (2007) 0.81
Rpd3- and spt16-mediated nucleosome assembly and transcriptional regulation on yeast ribosomal DNA genes. Mol Cell Biol (2013) 0.80
Ribonucleoproteins in archaeal pre-rRNA processing and modification. Archaea (2013) 0.79
Ribonucleoprotein multimers and their functions. Crit Rev Biochem Mol Biol (2010) 0.78
Determinants of mammalian nucleolar architecture. Chromosoma (2015) 0.77
Driving nucleolar assembly. Genes Dev (2014) 0.76
Long noncoding RNAs as sinks in Prader-Willi syndrome. Mol Cell (2012) 0.75
In vivo approaches to dissecting the function of RNA helicases in eukaryotic ribosome assembly. Methods Enzymol (2012) 0.75