IA-1, a new marker for neuroendocrine differentiation in human lung cancer cell lines.

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Published in Cancer Res on September 15, 1993

Authors

M S Lan1, E K Russell, J Lu, B E Johnson, A L Notkins

Author Affiliations

1: Laboratory of Oral Medicine, National Institute of Dental Research, NIH, Bethesda 20892.

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Rapid micro-radioimmunoassay for the measurement of antiviral antibody. J Immunol (1972) 1.79

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Multiple interferons in the circulation of patients with systemic lupus erythematosus and vasculitis. Arthritis Rheum (1982) 1.73

Antibodies against autologous tumor cell proteins in patients with small-cell lung cancer: association with improved survival. J Natl Cancer Inst (1993) 1.73