Published in Int J Biochem Cell Biol on November 01, 2002
Transcriptomic changes in human breast cancer progression as determined by serial analysis of gene expression. Breast Cancer Res (2004) 1.71
Apoptosis and molecular targeting therapy in cancer. Biomed Res Int (2014) 1.47
Functional annotation of the human retinal pigment epithelium transcriptome. BMC Genomics (2009) 1.22
Clusterin, a haploinsufficient tumor suppressor gene in neuroblastomas. J Natl Cancer Inst (2009) 1.19
Intracellular clusterin inhibits mitochondrial apoptosis by suppressing p53-activating stress signals and stabilizing the cytosolic Ku70-Bax protein complex. Clin Cancer Res (2009) 1.16
Clusterin is a secreted marker for a hypoxia-inducible factor-independent function of the von Hippel-Lindau tumor suppressor protein. Am J Pathol (2006) 1.16
Clusterin as a biomarker in murine and human intestinal neoplasia. Proc Natl Acad Sci U S A (2003) 1.15
The role of complement in tumor growth. Adv Exp Med Biol (2014) 1.11
Loss of clusterin both in serum and tissue correlates with the tumorigenesis of esophageal squamous cell carcinoma via proteomics approaches. World J Gastroenterol (2003) 1.09
Cell cycle and aging, morphogenesis, and response to stimuli genes are individualized biomarkers of glioblastoma progression and survival. BMC Med Genomics (2011) 1.04
Update on options for treatment of metastatic castration-resistant prostate cancer. Onco Targets Ther (2010) 1.00
Clusterin and DNA repair: a new function in cancer for a key player in apoptosis and cell cycle control. J Mol Histol (2006) 1.00
Influenza A virus nucleoprotein induces apoptosis in human airway epithelial cells: implications of a novel interaction between nucleoprotein and host protein Clusterin. Cell Death Dis (2013) 0.93
Clusterin expression can be modulated by changes in TCF1-mediated Wnt signaling. J Mol Signal (2007) 0.92
Quantitative proteomics analysis of early recurrence/metastasis of huge hepatocellular carcinoma following radical resection. Proteome Sci (2014) 0.92
Heat shock proteins and amateur chaperones in amyloid-Beta accumulation and clearance in Alzheimer's disease. Mol Neurobiol (2007) 0.92
Regulation of complement and modulation of its activity in monoclonal antibody therapy of cancer. MAbs (2014) 0.91
Clusterin attenuates the development of renal fibrosis. J Am Soc Nephrol (2011) 0.90
Genetic and epigenetic factors: Role in male infertility. Indian J Urol (2011) 0.89
Clusterin and LRP2 are critical components of the hypothalamic feeding regulatory pathway. Nat Commun (2013) 0.89
Oncogenic role of clusterin overexpression in multistage colorectal tumorigenesis and progression. World J Gastroenterol (2005) 0.88
Identification of clusterin domain involved in NF-kappaB pathway regulation. J Biol Chem (2009) 0.88
Clusterin confers gemcitabine resistance in pancreatic cancer. World J Surg Oncol (2011) 0.88
Role of gene methylation in antitumor immune response: implication for tumor progression. Cancers (Basel) (2011) 0.87
Trichinella spiralis: nurse cell formation with emphasis on analogy to muscle cell repair. Parasit Vectors (2008) 0.86
ATM regulates insulin-like growth factor 1-secretory clusterin (IGF-1-sCLU) expression that protects cells against senescence. PLoS One (2014) 0.85
Multidimensional liquid chromatography platform for profiling alterations of clusterin N-glycosylation in the plasma of patients with renal cell carcinoma. J Chromatogr A (2012) 0.85
Vanadium-induced apoptosis of HaCaT cells is mediated by c-fos and involves nuclear accumulation of clusterin. FEBS J (2009) 0.84
Alterations in expression, proteolysis and intracellular localizations of clusterin in esophageal squamous cell carcinoma. World J Gastroenterol (2004) 0.84
Identification of increased amounts of eppin protein complex components in sperm cells of diabetic and obese individuals by difference gel electrophoresis. Mol Cell Proteomics (2011) 0.84
The application of a three-step serum proteome analysis for the discovery and identification of novel biomarkers of hepatocellular carcinoma. Int J Proteomics (2012) 0.84
Tumor biomarker glycoproteins in the seminal plasma of healthy human males are endogenous ligands for DC-SIGN. Mol Cell Proteomics (2011) 0.83
Global analysis of gene expression in mammalian kidney. Pflugers Arch (2004) 0.83
The effects of ACE inhibitor and angiotensin receptor blocker on clusterin and apoptosis in the kidney tissue of streptozotocin-diabetic rats. J Mol Histol (2008) 0.83
Multiple pathways regulating the anti-apoptotic protein clusterin in breast cancer. Biochim Biophys Acta (2007) 0.82
Clusterin/apolipoprotein J attenuates angiotensin II-induced renal fibrosis. PLoS One (2014) 0.81
Dietary oil modifies the plasma proteome during aging in the rat. Age (Dordr) (2011) 0.80
Central Nervous System Lipoproteins: ApoE and Regulation of Cholesterol Metabolism. Arterioscler Thromb Vasc Biol (2016) 0.80
Clusterin associates with altered elastic fibers in human photoaged skin and prevents elastin from ultraviolet-induced aggregation in vitro. Am J Pathol (2007) 0.80
Mouse mammary tumor virus suppresses apoptosis of mammary epithelial cells through ITAM-mediated signaling. J Virol (2012) 0.79
Plasma Clusterin and Lipid Profile: A Link with Aging and Cardiovascular Diseases in a Population with a Consistent Number of Centenarians. PLoS One (2015) 0.79
Biological monitoring of hexavalent chromium and serum levels of the senescence biomarker apolipoprotein J/Clusterin in welders. Bioinorg Chem Appl (2008) 0.79
Centenarians and supercentenarians: a black swan. Emerging social, medical and surgical problems. BMC Surg (2012) 0.79
Direct Interaction of Selenoprotein R with Clusterin and Its Possible Role in Alzheimer's Disease. PLoS One (2013) 0.78
When the brain goes diving: transcriptome analysis reveals a reduced aerobic energy metabolism and increased stress proteins in the seal brain. BMC Genomics (2016) 0.78
Ocular clusterin expression in von Hippel-Lindau disease. Mol Vis (2007) 0.77
Serum proteomics analysis and comparisons using iTRAQ in the progression of hepatitis B. Exp Ther Med (2013) 0.77
Serum clusterin as a tumor marker and prognostic factor for patients with esophageal cancer. Dis Markers (2014) 0.77
Clusterin induced by N,N'-Dinitrosopiperazine is involved in nasopharyngeal carcinoma metastasis. Oncotarget (2016) 0.76
Hypoxia inducible factor-1α directly regulates nuclear clusterin transcription by interacting with hypoxia response elements in the clusterin promoter. Mol Cells (2014) 0.76
Exposure to acoustic stimuli promotes the development and differentiation of neural stem cells from the cochlear nuclei through the clusterin pathway. Int J Mol Med (2015) 0.76
Clusterin Seals the Ocular Surface Barrier in Mouse Dry Eye. PLoS One (2015) 0.76
Plasma clusterin as a candidate pre-diagnosis marker of colorectal cancer risk in the Florence cohort of the European Prospective Investigation into Cancer and Nutrition: a pilot study. BMC Cancer (2015) 0.76
Presence, localization, and origin of clusterin in normal human spermatozoa. J Assist Reprod Genet (2012) 0.76
Association between clusterin polymorphisms and esophageal squamous cell carcinoma risk in Han Chinese population. Int J Clin Exp Med (2015) 0.75
Prognostic Role of Secretory Clusterin in Multiple Human Malignant Neoplasms: A Meta-Analysis of 26 Immunohistochemistry Studies. PLoS One (2016) 0.75
Clusterin facilitates apoptotic cell clearance and prevents apoptotic cell-induced autoimmune responses. Cell Death Dis (2016) 0.75
The tumor suppressor von Hippel-Lindau gene product and metastasis: new thoughts on an old molecule. Am J Pathol (2006) 0.75
Magnetic Bead-Based Serum Peptidome Profiling in Patients with Gestational Diabetes Mellitus. Biomed Res Int (2015) 0.75
Effects of down-regulation of clusterin by small interference RNA on human acute myeloid leukemia cells. Int J Clin Exp Med (2015) 0.75
Apolipoprotein J: A New Predictor and Therapeutic Target in Cardiovascular Disease? Chin Med J (Engl) (2015) 0.75
Clusterin/Apolipoprotein J immunoreactivity is associated with white matter damage in cerebral small vessel diseases. Neuropathol Appl Neurobiol (2015) 0.75
Hepatitis D and hepatocellular carcinoma. World J Hepatol (2015) 0.75
Urine clusterin/apolipoprotein J is linked to tubular damage and renal outcomes in patients with type 2 diabetes mellitus. Clin Endocrinol (Oxf) (2017) 0.75
Quantitative proteomics reveal the anti-tumour mechanism of the carbohydrate recognition domain of Galectin-3 in Hepatocellular carcinoma. Sci Rep (2017) 0.75
Novel panel of protein biomarkers to predict response to bortezomib-containing induction regimens in multiple myeloma patients. BBA Clin (2017) 0.75
Protective effect of clusterin on rod photoreceptor in rat model of retinitis pigmentosa. PLoS One (2017) 0.75
The co-occurrence of mtDNA mutations on different oxidative phosphorylation subunits, not detected by haplogroup analysis, affects human longevity and is population specific. Aging Cell (2013) 1.56
Central role of the proteasome in senescence and survival of human fibroblasts: induction of a senescence-like phenotype upon its inhibition and resistance to stress upon its activation. J Biol Chem (2003) 1.51
Overexpression of proteasome beta5 assembled subunit increases the amount of proteasome and confers ameliorated response to oxidative stress and higher survival rates. J Biol Chem (2005) 1.43
Regulation of clusterin/apolipoprotein J, a functional homologue to the small heat shock proteins, by oxidative stress in ageing and age-related diseases. Free Radic Res (2006) 1.40
Postmitotic neurons develop a p21-dependent senescence-like phenotype driven by a DNA damage response. Aging Cell (2012) 1.35
Genome-wide linkage analysis for human longevity: Genetics of Healthy Aging Study. Aging Cell (2013) 1.33
The genetics of human longevity. Ann N Y Acad Sci (2006) 1.30
Development of resistance to chemotherapeutic drugs in human osteosarcoma cell lines largely depends on up-regulation of Clusterin/Apolipoprotein J. Int J Cancer (2007) 1.27
Proteasome dysfunction in mammalian aging: steps and factors involved. Exp Gerontol (2005) 1.27
Advances and challenges in basic and translational research on clusterin. Cancer Res (2009) 1.20
Intracellular clusterin inhibits mitochondrial apoptosis by suppressing p53-activating stress signals and stabilizing the cytosolic Ku70-Bax protein complex. Clin Cancer Res (2009) 1.16
Nuclear erythroid factor 2-mediated proteasome activation delays senescence in human fibroblasts. J Biol Chem (2010) 1.16
Serum levels of the senescence biomarker clusterin/apolipoprotein J increase significantly in diabetes type II and during development of coronary heart disease or at myocardial infarction. Exp Gerontol (2002) 1.09
What evidence is there for the existence of individual genes with antagonistic pleiotropic effects? Mech Ageing Dev (2005) 1.03
The olive constituent oleuropein exhibits proteasome stimulatory properties in vitro and confers life span extension of human embryonic fibroblasts. Rejuvenation Res (2007) 1.01
Differential effects of clusterin/apolipoprotein J on cellular growth and survival. Free Radic Biol Med (2005) 1.01
What studies on human longevity tell us about the risk for cancer in the oldest old: data and hypotheses on the genetics and immunology of centenarians. Exp Gerontol (2002) 0.97
Overexpression of apolipoprotein J in human fibroblasts protects against cytotoxicity and premature senescence induced by ethanol and tert-butylhydroperoxide. Cell Stress Chaperones (2002) 0.96
Identification of a candidate tumor-suppressor gene specifically activated during Ras-induced senescence. Exp Cell Res (2002) 0.95
Identification of differentially expressed proteins in senescent human embryonic fibroblasts. Mech Ageing Dev (2005) 0.95
Proteasome inhibition induces a senescence-like phenotype in primary human fibroblasts cultures. Biogerontology (2004) 0.92
Anti-ageing and rejuvenating effects of quercetin. Exp Gerontol (2010) 0.91
Chapter 9: Oxidative stress in malignant progression: The role of Clusterin, a sensitive cellular biosensor of free radicals. Adv Cancer Res (2009) 0.89
Overexpression of hUMP1/POMP proteasome accessory protein enhances proteasome-mediated antioxidant defence. Exp Gerontol (2007) 0.89
The proteasome is an integral part of solar ultraviolet a radiation-induced gene expression. J Biol Chem (2009) 0.87
CHIP-dependent p53 regulation occurs specifically during cellular senescence. Free Radic Biol Med (2010) 0.87
Protein degradation during aging: the lysosome-, the calpain- and the proteasome-dependent cellular proteolytic systems. Biogerontology (2002) 0.87
Cloning of differentially expressed genes in skin fibroblasts from centenarians. Biogerontology (2004) 0.87
Proteasome response to interferon-gamma is altered in senescent human fibroblasts. FEBS Lett (2006) 0.87
Comparative effects of hypoxia on normal and immortalized human diploid fibroblasts. Anticancer Res (2006) 0.86
Proteasome activation as a novel antiaging strategy. IUBMB Life (2008) 0.86
Functional analysis of clusterin/apolipoprotein J in cellular death induced by severe genotoxic stress. Ann N Y Acad Sci (2004) 0.85
Proteasome function determines cellular homeostasis and the rate of aging. Adv Exp Med Biol (2010) 0.84
Vanadium-induced apoptosis of HaCaT cells is mediated by c-fos and involves nuclear accumulation of clusterin. FEBS J (2009) 0.84
Partial proteasome inhibition in human fibroblasts triggers accelerated M1 senescence or M2 crisis depending on p53 and Rb status. Aging Cell (2008) 0.83
A novel mitochondrial DNA-like sequence insertion polymorphism in Intron I of the FOXO1A gene. Gene (2004) 0.82
Exposure of human diploid fibroblasts to hypoxia extends proliferative life span. Ann N Y Acad Sci (2007) 0.82
CHIP E3 ligase regulates mammalian senescence by modulating the levels of oxidized proteins. Mech Ageing Dev (2011) 0.82
Clusterin/Apolipoprotein J up-regulation after zinc exposure, replicative senescence or differentiation of human haematopoietic cells. Biogerontology (2006) 0.82
Reduced expression levels of the senescence biomarker clusterin/apolipoprotein j in lymphocytes from healthy centenarians. Ann N Y Acad Sci (2006) 0.81
CRM1 protein-mediated regulation of nuclear clusterin (nCLU), an ionizing radiation-stimulated, Bax-dependent pro-death factor. J Biol Chem (2011) 0.81
Structure and function of the ubiquitin-proteasome system: modulation of components. Prog Mol Biol Transl Sci (2012) 0.80
Bcl-2 but not clusterin/apolipoprotein J protected human diploid fibroblasts and immortalized keratinocytes from ceramide-induced apoptosis: role of p53 in the ceramide response. Arch Biochem Biophys (2005) 0.80
Transcriptional and posttranslational regulation of clusterin by the two main cellular proteolytic pathways. Free Radic Biol Med (2009) 0.79
Biological monitoring of hexavalent chromium and serum levels of the senescence biomarker apolipoprotein J/Clusterin in welders. Bioinorg Chem Appl (2008) 0.79
Alterations of senescence biomarkers in human cells by exposure to CrVI in vivo and in vitro. Exp Gerontol (2004) 0.79
High-resolution quantitative metabolome analysis of urine by automated flow injection NMR. Anal Chem (2013) 0.78
The 19S proteasome subunit Rpn7 stabilizes DNA damage foci upon genotoxic insult. IUBMB Life (2012) 0.78
Ectopic expression of clusterin/apolipoprotein J or Bcl-2 decreases the sensitivity of HaCaT cells to toxic effects of ropivacaine. Cell Res (2004) 0.78
Genome-wide transcriptome profile of the human osteosarcoma Sa OS and U-2 OS cell lines. Cancer Genet Cytogenet (2010) 0.77
Zinc, metallothioneins, and longevity--effect of zinc supplementation: zincage study. Ann N Y Acad Sci (2007) 0.77
Mediterranean diet and inflammaging in the elderly: the European project NU-AGE. Preface. Mech Ageing Dev (2014) 0.76
Cloning approaches for identifying aging and longevity-related genes in mammals. ScientificWorldJournal (2002) 0.75