Published in J Biol Chem on September 12, 2002
Mechanisms of change in gene copy number. Nat Rev Genet (2009) 9.01
Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks. J Cell Biol (2006) 6.52
Requirement of the MRN complex for ATM activation by DNA damage. EMBO J (2003) 6.23
Independent and sequential recruitment of NHEJ and HR factors to DNA damage sites in mammalian cells. J Cell Biol (2005) 2.64
Human SMC5/6 complex promotes sister chromatid homologous recombination by recruiting the SMC1/3 cohesin complex to double-strand breaks. EMBO J (2006) 2.13
The annealing helicase HARP is recruited to DNA repair sites via an interaction with RPA. Genes Dev (2009) 1.96
S-phase checkpoint genes safeguard high-fidelity sister chromatid cohesion. Mol Biol Cell (2004) 1.88
Comparative analysis of different laser systems to study cellular responses to DNA damage in mammalian cells. Nucleic Acids Res (2009) 1.83
Pulsed laser microbeam-induced cell lysis: time-resolved imaging and analysis of hydrodynamic effects. Biophys J (2006) 1.81
Mre11 assembles linear DNA fragments into DNA damage signaling complexes. PLoS Biol (2004) 1.79
The yeast chromatin remodeler RSC complex facilitates end joining repair of DNA double-strand breaks. Mol Cell Biol (2005) 1.76
H2AX Phosphorylation: Its Role in DNA Damage Response and Cancer Therapy. J Nucleic Acids (2010) 1.69
Nse1, Nse2, and a novel subunit of the Smc5-Smc6 complex, Nse3, play a crucial role in meiosis. Mol Biol Cell (2004) 1.52
Double-strand breaks arising by replication through a nick are repaired by cohesin-dependent sister-chromatid exchange. EMBO Rep (2006) 1.51
The ancient and evolving roles of cohesin in gene expression and DNA repair. Curr Biol (2012) 1.49
A polycomb group protein, PHF1, is involved in the response to DNA double-strand breaks in human cell. Nucleic Acids Res (2008) 1.47
Imaging of protein movement induced by chromosomal breakage: tiny 'local' lesions pose great 'global' challenges. Chromosoma (2005) 1.34
Cohesin Is limiting for the suppression of DNA damage-induced recombination between homologous chromosomes. PLoS Genet (2010) 1.31
The Smc complexes in DNA damage response. Cell Biosci (2012) 1.31
H2AX chromatin structures and their response to DNA damage revealed by 4Pi microscopy. Proc Natl Acad Sci U S A (2006) 1.27
SMC1 coordinates DNA double-strand break repair pathways. Nucleic Acids Res (2004) 1.19
Structure and DNA binding activity of the mouse condensin hinge domain highlight common and diverse features of SMC proteins. Nucleic Acids Res (2010) 1.17
Cohesin protects genes against γH2AX Induced by DNA double-strand breaks. PLoS Genet (2012) 1.17
Cohesin promotes the repair of ionizing radiation-induced DNA double-strand breaks in replicated chromatin. Nucleic Acids Res (2009) 1.17
Molecular characterization of the Schizosaccharomyces pombe nbs1+ gene involved in DNA repair and telomere maintenance. Mol Cell Biol (2003) 1.09
Inhibition of transcription at radiation-induced nuclear foci of phosphorylated histone H2AX in mammalian cells. Chromosome Res (2007) 1.08
DNA damage response. Cold Spring Harb Perspect Biol (2011) 1.03
Scc1 sumoylation by Mms21 promotes sister chromatid recombination through counteracting Wapl. Genes Dev (2012) 1.02
Cohesin associates with spindle poles in a mitosis-specific manner and functions in spindle assembly in vertebrate cells. Mol Biol Cell (2008) 1.00
Shaping meiotic prophase chromosomes: cohesins and synaptonemal complex proteins. Chromosoma (2006) 1.00
Sister chromatids are often incompletely aligned in meristematic and endopolyploid interphase nuclei of Arabidopsis thaliana. Genetics (2005) 0.99
RSC facilitates Rad59-dependent homologous recombination between sister chromatids by promoting cohesin loading at DNA double-strand breaks. Mol Cell Biol (2011) 0.99
Recombination protein Tid1p controls resolution of cohesin-dependent linkages in meiosis in Saccharomyces cerevisiae. J Cell Biol (2005) 0.97
Cohesin gene defects may impair sister chromatid alignment and genome stability in Arabidopsis thaliana. Chromosoma (2009) 0.93
Mechanisms of ectopic gene conversion. Genes (Basel) (2010) 0.92
A novel mechanism for the establishment of sister chromatid cohesion by the ECO1 acetyltransferase. Mol Biol Cell (2014) 0.92
Damage site chromatin: open or closed? Curr Opin Cell Biol (2011) 0.92
Cohesin regulates MHC class II genes through interactions with MHC class II insulators. J Immunol (2011) 0.91
Chromatin remodeling and repair of DNA double-strand breaks. J Mol Histol (2006) 0.89
Analysis of DNA double-strand break response and chromatin structure in mitosis using laser microirradiation. Nucleic Acids Res (2010) 0.88
The sister chromatid cohesion pathway suppresses multiple chromosome gain and chromosome amplification. Genetics (2013) 0.87
Nuclear dynamics of radiation-induced foci in euchromatin and heterochromatin. Mutat Res (2013) 0.87
The control of DNA repair by the cell cycle. Nat Cell Biol (2016) 0.86
Resolving RAD51C function in late stages of homologous recombination. Cell Div (2007) 0.85
SMC complexes in bacterial chromosome condensation and segregation. Plasmid (2005) 0.85
Cohesin: a critical chromatin organizer in mammalian gene regulation. Biochem Cell Biol (2011) 0.84
Ionizing radiation-induced DNA injury and damage detection in patients with breast cancer. Genet Mol Biol (2015) 0.84
SepBCTF4 is required for the formation of DNA-damage-induced UvsCRAD51 foci in Aspergillus nidulans. Genetics (2005) 0.82
Distinct functions of human cohesin-SA1 and cohesin-SA2 in double-strand break repair. Mol Cell Biol (2013) 0.82
A novel and simple micro-irradiation technique for creating localized DNA double-strand breaks. Nucleic Acids Res (2010) 0.82
Condensin I recruitment to base damage-enriched DNA lesions is modulated by PARP1. PLoS One (2011) 0.82
Increased sister chromatid cohesion and DNA damage response factor localization at an enzyme-induced DNA double-strand break in vertebrate cells. Nucleic Acids Res (2009) 0.82
Creating localized DNA double-strand breaks with microirradiation. Nat Protoc (2011) 0.81
Radiation microbeams as spatial and temporal probes of subcellular and tissue response. Mutat Res (2010) 0.81
Loss of Caenorhabditis elegans BRCA1 promotes genome stability during replication in smc-5 mutants. Genetics (2014) 0.81
Spatially sculpted laser scissors for study of DNA damage and repair. J Biomed Opt (2009) 0.80
Histone tail-independent chromatin binding activity of recombinant cohesin holocomplex. J Biol Chem (2003) 0.79
Arabidopsis sister chromatids often show complete alignment or separation along a 1.2-Mb euchromatic region but no cohesion "hot spots". Chromosoma (2008) 0.78
Damage-induced reactivation of cohesin in postreplicative DNA repair. Bioessays (2008) 0.78
And yet, it moves: nuclear and chromatin dynamics of a heterochromatic double-strand break. Philos Trans R Soc Lond B Biol Sci (2017) 0.78
Disruption of CHTF18 causes defective meiotic recombination in male mice. PLoS Genet (2012) 0.77
Condensin suppresses recombination and regulates double-strand break processing at the repetitive ribosomal DNA array to ensure proper chromosome segregation during meiosis in budding yeast. Mol Biol Cell (2014) 0.77
Targeting telomere-containing chromosome ends with a near-infrared femtosecond laser to study the activation of the DNA damage response and DNA damage repair pathways. J Biomed Opt (2013) 0.76
Generation of cell-based systems to visualize chromosome damage and translocations in living cells. Nat Protoc (2014) 0.76
Variations in dysfunction of sister chromatid cohesion in esco2 mutant zebrafish reflect the phenotypic diversity of Roberts syndrome. Dis Model Mech (2015) 0.76
Roles for APRIN (PDS5B) in homologous recombination and in ovarian cancer prediction. Nucleic Acids Res (2016) 0.76
Independent mechanisms recruit the cohesin loader protein NIPBL to sites of DNA damage. J Cell Sci (2017) 0.75
Involvement of the Cohesin Cofactor PDS5 (SPO76) During Meiosis and DNA Repair in Arabidopsis thaliana. Front Plant Sci (2015) 0.75
Functions of the MRE11 complex in the development and maintenance of oocytes. Chromosoma (2015) 0.75
SGO1 is involved in the DNA damage response in MYCN-amplified neuroblastoma cells. Sci Rep (2016) 0.75
Nuclear Dynamics of Heterochromatin Repair. Trends Genet (2017) 0.75
Real-time imaging of DNA damage in yeast cells using ultra-short near-infrared pulsed laser irradiation. PLoS One (2014) 0.75
Structural Maintenance of Chromosomes protein 1: Role in Genome Stability and Tumorigenesis. Int J Biol Sci (2017) 0.75
Cohesins functionally associate with CTCF on mammalian chromosome arms. Cell (2008) 7.80
MDC1 is a mediator of the mammalian DNA damage checkpoint. Nature (2003) 6.81
The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage. Cell (2009) 5.96
Specific loss of histone H3 lysine 9 trimethylation and HP1gamma/cohesin binding at D4Z4 repeats is associated with facioscapulohumeral dystrophy (FSHD). PLoS Genet (2009) 2.90
Independent and sequential recruitment of NHEJ and HR factors to DNA damage sites in mammalian cells. J Cell Biol (2005) 2.64
A chromatin remodelling complex that loads cohesin onto human chromosomes. Nature (2002) 2.53
Multiple organ system defects and transcriptional dysregulation in the Nipbl(+/-) mouse, a model of Cornelia de Lange Syndrome. PLoS Genet (2009) 2.14
The PARP inhibitor olaparib induces significant killing of ATM-deficient lymphoid tumor cells in vitro and in vivo. Blood (2010) 2.09
The annealing helicase HARP is recruited to DNA repair sites via an interaction with RPA. Genes Dev (2009) 1.96
The ataxia-oculomotor apraxia 1 gene product has a role distinct from ATM and interacts with the DNA strand break repair proteins XRCC1 and XRCC4. DNA Repair (Amst) (2004) 1.86
Comparative analysis of different laser systems to study cellular responses to DNA damage in mammalian cells. Nucleic Acids Res (2009) 1.83
Mutations in the ATM gene lead to impaired overall and treatment-free survival that is independent of IGVH mutation status in patients with B-CLL. Blood (2005) 1.81
RIDDLE immunodeficiency syndrome is linked to defects in 53BP1-mediated DNA damage signaling. Proc Natl Acad Sci U S A (2007) 1.79
Noninvasive imaging of angiotensin receptors after myocardial infarction. JACC Cardiovasc Imaging (2008) 1.67
The alternative Ctf18-Dcc1-Ctf8-replication factor C complex required for sister chromatid cohesion loads proliferating cell nuclear antigen onto DNA. Proc Natl Acad Sci U S A (2003) 1.62
Combined multiphoton microscopy and optical coherence tomography using a 12-fs broadband source. J Biomed Opt (2006) 1.61
Effect of excitation wavelength on penetration depth in nonlinear optical microscopy of turbid media. J Biomed Opt (2009) 1.54
Condensin I interacts with the PARP-1-XRCC1 complex and functions in DNA single-strand break repair. Mol Cell (2006) 1.54
Regulation of DNA-end resection by hnRNPU-like proteins promotes DNA double-strand break signaling and repair. Mol Cell (2012) 1.50
Inhibitors of the proteasome suppress homologous DNA recombination in mammalian cells. Cancer Res (2007) 1.48
Isolation and characterization of a novel DNA methyltransferase complex linking DNMT3B with components of the mitotic chromosome condensation machinery. Nucleic Acids Res (2004) 1.44
RAD18 and poly(ADP-ribose) polymerase independently suppress the access of nonhomologous end joining to double-strand breaks and facilitate homologous recombination-mediated repair. Mol Cell Biol (2007) 1.41
UNC-51/ATG1 kinase regulates axonal transport by mediating motor-cargo assembly. Genes Dev (2008) 1.40
Miniaturized probe based on a microelectromechanical system mirror for multiphoton microscopy. Opt Lett (2008) 1.39
Dynamic regulation of the PR-Set7 histone methyltransferase is required for normal cell cycle progression. Genes Dev (2010) 1.38
Biallelic ATM inactivation significantly reduces survival in patients treated on the United Kingdom Leukemia Research Fund Chronic Lymphocytic Leukemia 4 trial. J Clin Oncol (2012) 1.36
Effect of pulse duration on two-photon excited fluorescence and second harmonic generation in nonlinear optical microscopy. J Biomed Opt (2006) 1.36
Cohesin mediates chromatin interactions that regulate mammalian β-globin expression. J Biol Chem (2011) 1.29
Epithelial-derived TGF-beta2 modulates basal and wound-healing subepithelial matrix homeostasis. Am J Physiol Lung Cell Mol Physiol (2006) 1.25
Detection and diagnosis of oral cancer by light-induced fluorescence. Lasers Surg Med (2003) 1.18
Adenovirus 12 E4orf6 inhibits ATR activation by promoting TOPBP1 degradation. Proc Natl Acad Sci U S A (2010) 1.17
Imaging subcellular scattering contrast by using combined optical coherence and multiphoton microscopy. Opt Lett (2007) 1.16
HP1: heterochromatin binding proteins working the genome. Epigenetics (2010) 1.16
Delineation of the role of the Mre11 complex in class switch recombination. J Biol Chem (2004) 1.16
Developing compact multiphoton systems using femtosecond fiber lasers. J Biomed Opt (2009) 1.14
In vivo multiphoton NADH fluorescence reveals depth-dependent keratinocyte metabolism in human skin. Biophys J (2013) 1.13
Three-dimensional spheroid culture of human gingiva-derived mesenchymal stem cells enhances mitigation of chemotherapy-induced oral mucositis. Stem Cells Dev (2011) 1.12
The acetyltransferase activity of San stabilizes the mitotic cohesin at the centromeres in a shugoshin-independent manner. J Cell Biol (2007) 1.12
A role for E1B-AP5 in ATR signaling pathways during adenovirus infection. J Virol (2008) 1.11
In-depth activation of channelrhodopsin 2-sensitized excitable cells with high spatial resolution using two-photon excitation with a near-infrared laser microbeam. Biophys J (2008) 1.10
Hypomorphic PCNA mutation underlies a human DNA repair disorder. J Clin Invest (2014) 1.07
Immunostaining of modified histones defines high-level features of the human metaphase epigenome. Genome Biol (2010) 1.07
Identification of the first ATRIP-deficient patient and novel mutations in ATR define a clinical spectrum for ATR-ATRIP Seckel Syndrome. PLoS Genet (2012) 1.06
Correlation analysis of clinical parameters with epigenetic modifications in the DUX4 promoter in FSHD. Epigenetics (2012) 1.06
AREM: aligning short reads from ChIP-sequencing by expectation maximization. J Comput Biol (2011) 1.05
Variations in ATM protein expression during normal lymphoid differentiation and among B-cell-derived neoplasias. Am J Pathol (2003) 1.05
Scc1 sumoylation by Mms21 promotes sister chromatid recombination through counteracting Wapl. Genes Dev (2012) 1.02
Imaging corneal pathology in a transgenic mouse model using nonlinear microscopy. J Biomed Opt (2006) 1.02
Cohesin associates with spindle poles in a mitosis-specific manner and functions in spindle assembly in vertebrate cells. Mol Biol Cell (2008) 1.00
Condensin I reveals new insights on mouse meiotic chromosome structure and dynamics. PLoS One (2007) 0.95
Bmi-1 is induced by the Epstein-Barr virus oncogene LMP1 and regulates the expression of viral target genes in Hodgkin lymphoma cells. Blood (2006) 0.93
In situ analysis of DNA damage response and repair using laser microirradiation. Methods Cell Biol (2007) 0.93
Modeling ATM mutant proteins from missense changes confirms retained kinase activity. Hum Mutat (2009) 0.92
Damage site chromatin: open or closed? Curr Opin Cell Biol (2011) 0.92
Recruitment of DNA damage recognition and repair pathway proteins following near-IR femtosecond laser irradiation of cells. J Biomed Opt (2007) 0.90
Identification of a chromosome-targeting domain in the human condensin subunit CNAP1/hCAP-D2/Eg7. Mol Cell Biol (2002) 0.89
Analysis of DNA double-strand break response and chromatin structure in mitosis using laser microirradiation. Nucleic Acids Res (2010) 0.88
Adult-onset ataxia telangiectasia due to ATM 5762ins137 mutation homozygosity. Ann Neurol (2004) 0.88
Revisiting the role of heterochromatin protein 1 in DNA repair. J Cell Biol (2009) 0.88
Premature ageing of the immune system underlies immunodeficiency in ataxia telangiectasia. Clin Immunol (2011) 0.87
Rhabdomyosarcoma in Nijmegen breakage syndrome: strong association with perianal primary site. Cancer Genet Cytogenet (2004) 0.87
Mre11 modulates the fidelity of fusion between short telomeres in human cells. Nucleic Acids Res (2011) 0.86
Prominent oromandibular dystonia and pharyngeal telangiectasia in atypical ataxia telangiectasia. Cerebellum (2009) 0.85
Genetic and epigenetic characteristics of FSHD-associated 4q and 10q D4Z4 that are distinct from non-4q/10q D4Z4 homologs. Hum Mutat (2014) 0.84
Cohesin: a critical chromatin organizer in mammalian gene regulation. Biochem Cell Biol (2011) 0.84
Atypical presentation of ataxia-oculomotor apraxia type 1. Dev Med Child Neurol (2006) 0.84
Localization of human SMC1 protein at kinetochores. Chromosome Res (2002) 0.83
Distinct functions of human cohesin-SA1 and cohesin-SA2 in double-strand break repair. Mol Cell Biol (2013) 0.82
Pathogenic ATM mutations occur rarely in a subset of multiple myeloma patients. Br J Haematol (2008) 0.82
Autosomal recessive spinocerebellar ataxia and peripheral neuropathy with raised alpha-fetoprotein. J Neurol (2004) 0.82
Condensin I recruitment to base damage-enriched DNA lesions is modulated by PARP1. PLoS One (2011) 0.82
Differential association of SMC1alpha and SMC3 proteins with meiotic chromosomes in wild-type and SPO11-deficient male mice. Chromosome Res (2002) 0.81
Effect of genipin crosslinking on the optical spectral properties and structures of collagen hydrogels. ACS Appl Mater Interfaces (2011) 0.81
Treatment of hypertrophic scars and keloids with a radiofrequency device: a study of collagen effects. Lasers Surg Med (2005) 0.81
Nitrosyl-cobinamide (NO-Cbi), a new nitric oxide donor, improves wound healing through cGMP/cGMP-dependent protein kinase. Cell Signal (2013) 0.80
Multiscale analysis of collagen microstructure with generalized image correlation spectroscopy and the detection of tissue prestress. Biomaterials (2013) 0.80
Spatially sculpted laser scissors for study of DNA damage and repair. J Biomed Opt (2009) 0.80
Cornelia de Lange syndrome: further delineation of phenotype, cohesin biology and educational focus, 5th Biennial Scientific and Educational Symposium abstracts. Am J Med Genet A (2014) 0.79
Variant ataxia telangiectasia: clinical and molecular findings and evaluation of radiosensitive phenotypes in a patient and relatives. Neuromolecular Med (2013) 0.79
Association between promyelocyte protein and small ubiquitin-like modifier protein and the progression of cervical neoplasia. Obstet Gynecol (2003) 0.79
Very mild presentation in adult with classical cellular phenotype of ataxia telangiectasia. Mov Disord (2012) 0.78
Damage-induced reactivation of cohesin in postreplicative DNA repair. Bioessays (2008) 0.78
A regulatory role for NBS1 in strand-specific mutagenesis during somatic hypermutation. PLoS One (2008) 0.78
In situ multiphoton optical tomography of hair follicles in mice. J Biomed Opt (2007) 0.78
Multiphoton imaging of actin filament formation and mitochondrial energetics of human ACBT gliomas. Photochem Photobiol (2011) 0.77
Separation of a disulfide-linked phosphoprotein by diagonal SDS-PAGE with optimized gel crosslinking. Anal Biochem (2007) 0.76
Imaging of normal and pathologic joint synovium using nonlinear optical microscopy as a potential diagnostic tool. J Biomed Opt (2010) 0.75
Ataxia in a young patient. Pract Neurol (2011) 0.75