Published in J Cell Biochem on January 01, 2002
A genome-wide analysis of CpG dinucleotides in the human genome distinguishes two distinct classes of promoters. Proc Natl Acad Sci U S A (2006) 10.63
Loss of methylation in CpG sites in the NF-κB enhancer elements of inducible nitric oxide synthase is responsible for gene induction in human articular chondrocytes. Arthritis Rheum (2013) 1.70
Epigenetic mechanism of rRNA gene silencing: temporal order of NoRC-mediated histone modification, chromatin remodeling, and DNA methylation. Mol Cell Biol (2005) 1.66
Identification of driver and passenger DNA methylation in cancer by epigenomic analysis. Adv Genet (2010) 1.44
DNA methyltransferase 3b regulates nerve growth factor-induced differentiation of PC12 cells by recruiting histone deacetylase 2. Mol Cell Biol (2005) 1.41
Epigenetics of cervical cancer. An overview and therapeutic perspectives. Mol Cancer (2005) 1.40
L1 retrotransposons in human cancers. J Biomed Biotechnol (2006) 1.34
Gene-environment interactions and epigenetic basis of human diseases. Curr Issues Mol Biol (2008) 1.31
MSRE-PCR for analysis of gene-specific DNA methylation. Nucleic Acids Res (2005) 1.21
ChromDB: the chromatin database. Nucleic Acids Res (2007) 1.15
Role of histone deacetylation in cell-specific expression of endothelial nitric-oxide synthase. J Biol Chem (2005) 1.06
Role of DNA methyltransferases in regulation of human ribosomal RNA gene transcription. J Biol Chem (2006) 1.06
Profiling genome-wide chromatin methylation with engineered posttranslation apparatus within living cells. J Am Chem Soc (2013) 1.04
PscanChIP: Finding over-represented transcription factor-binding site motifs and their correlations in sequences from ChIP-Seq experiments. Nucleic Acids Res (2013) 1.01
Comparison of genetic and cytogenetic maps of hexaploid wheat (Triticum aestivum L.) using SSR and DArT markers. Mol Genet Genomics (2008) 1.01
Environmental studies of schizophrenia through the prism of epigenetics. Schizophr Bull (2008) 0.99
Inhibition of histone deacetylase activity promotes invasion of human cancer cells through activation of urokinase plasminogen activator. J Biol Chem (2007) 0.99
Epigenetic regulation in RCC: opportunities for therapeutic intervention? Nat Rev Urol (2012) 0.99
Identification of T-cadherin as a novel target of DNA methyltransferase 3B and its role in the suppression of nerve growth factor-mediated neurite outgrowth in PC12 cells. J Biol Chem (2006) 0.99
Hydralazine target: from blood vessels to the epigenome. J Transl Med (2006) 0.98
Regulation of p110delta PI 3-kinase gene expression. PLoS One (2009) 0.95
Genome-wide DNA methylation analysis in cohesin mutant human cell lines. Nucleic Acids Res (2010) 0.95
Palate morphogenesis: current understanding and future directions. Birth Defects Res C Embryo Today (2010) 0.94
TIMP3 and CCNA1 hypermethylation in HNSCC is associated with an increased incidence of second primary tumors. J Transl Med (2013) 0.92
RTA promoter demethylation and histone acetylation regulation of murine gammaherpesvirus 68 reactivation. PLoS One (2009) 0.85
Mandatory fortification with folic acid in the United States is associated with increased expression of DNA methyltransferase-1 in the cervix. Nutrition (2008) 0.85
The histone methyltransferase ESET is required for the survival of spermatogonial stem/progenitor cells in mice. Cell Death Dis (2014) 0.85
Osteo-Promoter Database (OPD) -- promoter analysis in skeletal cells. BMC Genomics (2005) 0.84
Epigenetic upregulation of urokinase plasminogen activator promotes the tropism of mesenchymal stem cells for tumor cells. Mol Cancer Res (2010) 0.84
Mapping of lysine methylation and acetylation in core histones of Neurospora crassa. Biochemistry (2010) 0.84
Targeted therapies in the treatment of advanced hepatocellular carcinoma. Clin Med Insights Oncol (2013) 0.83
Chromatin physics: Replacing multiple, representation-centered descriptions at discrete scales by a continuous, function-dependent self-scaled model. Eur Phys J E Soft Matter (2006) 0.82
Paramutation: the chromatin connection. Plant Cell (2004) 0.81
Developmental epigenetics of the murine secondary palate. ILAR J (2012) 0.81
Reversible post-translational carboxylation modulates the enzymatic activity of N-acetyl-L-ornithine transcarbamylase. Biochemistry (2010) 0.81
Nuclear respiratory factor 1 mediates the transcription initiation of insulin-degrading enzyme in a TATA box-binding protein-independent manner. PLoS One (2012) 0.80
Interconnection between flowering time control and activation of systemic acquired resistance. Front Plant Sci (2015) 0.78
Scriptaid Treatment Decreases DNA Methyltransferase 1 Expression by Induction of MicroRNA-152 Expression in Porcine Somatic Cell Nuclear Transfer Embryos. PLoS One (2015) 0.78
Aberrant DNA methylation of ESR1 and p14ARF genes could be useful as prognostic indicators in osteosarcoma. Onco Targets Ther (2013) 0.77
Histone modification of embryonic stem cells produced by somatic cell nuclear transfer and fertilized blastocysts. Cell J (2013) 0.77
Genome-wide analysis of DNA methylation in hepatoblastoma tissues. Oncol Lett (2016) 0.76
Conserved and divergent patterns of DNA methylation in higher vertebrates. Genome Biol Evol (2014) 0.76
The transposon-driven evolutionary origin and basis of histone deacetylase functions and limitations in disease prevention. Clin Epigenetics (2011) 0.75
Epigenetics: A key paradigm in reproductive health. Clin Exp Reprod Med (2016) 0.75
Aberrant KLK4 gene promoter hypomethylation in pediatric hepatoblastomas. Oncol Lett (2017) 0.75
No Evidence for a Parent-of-Origin Specific Differentially Methylated Region Linked to RASGRF1. Front Genet (2012) 0.75
Ultrastructural localization of 5-methylcytosine on DNA and RNA. Cell Mol Life Sci (2017) 0.75
A higher degree of expression of DNA methyl transferase 1 in cervical cancer is associated with poor survival outcome. Int J Womens Health (2017) 0.75
Specific loss of histone H3 lysine 9 trimethylation and HP1gamma/cohesin binding at D4Z4 repeats is associated with facioscapulohumeral dystrophy (FSHD). PLoS Genet (2009) 2.90
DNA methylation inhibitor 5-Aza-2'-deoxycytidine induces reversible genome-wide DNA damage that is distinctly influenced by DNA methyltransferases 1 and 3B. Mol Cell Biol (2007) 2.47
Epigenomic profiling reveals novel and frequent targets of aberrant DNA methylation-mediated silencing in malignant glioma. Cancer Res (2006) 2.00
DNA methylation in development and human disease. Mutat Res (2008) 1.74
DNA methyltransferase 3B (DNMT3B) mutations in ICF syndrome lead to altered epigenetic modifications and aberrant expression of genes regulating development, neurogenesis and immune function. Hum Mol Genet (2007) 1.65
Azacitidine induces demethylation of the Epstein-Barr virus genome in tumors. J Clin Oncol (2004) 1.65
Human DNA methyltransferase 1 is required for maintenance of the histone H3 modification pattern. J Biol Chem (2004) 1.64
DNA methyltransferases, DNA damage repair, and cancer. Adv Exp Med Biol (2013) 1.57
Modification of de novo DNA methyltransferase 3a (Dnmt3a) by SUMO-1 modulates its interaction with histone deacetylases (HDACs) and its capacity to repress transcription. Nucleic Acids Res (2004) 1.52
Inactivation of Wnt inhibitory factor-1 (WIF1) expression by epigenetic silencing is a common event in breast cancer. Carcinogenesis (2006) 1.47
DNA methylation: superior or subordinate in the epigenetic hierarchy? Genes Cancer (2011) 1.45
Isolation and characterization of a novel DNA methyltransferase complex linking DNMT3B with components of the mitotic chromosome condensation machinery. Nucleic Acids Res (2004) 1.44
DNMT3B interacts with constitutive centromere protein CENP-C to modulate DNA methylation and the histone code at centromeric regions. Hum Mol Genet (2009) 1.41
Defective de novo methylation of viral and cellular DNA sequences in ICF syndrome cells. Hum Mol Genet (2002) 1.32
Preferential methylation of unmethylated DNA by Mammalian de novo DNA methyltransferase Dnmt3a. J Biol Chem (2002) 1.30
Linking DNA methyltransferases to epigenetic marks and nucleosome structure genome-wide in human tumor cells. Cell Rep (2012) 1.27
DNMT1 and DNMT3B modulate distinct polycomb-mediated histone modifications in colon cancer. Cancer Res (2009) 1.26
Epigenetic silencing of the tumor suppressor cystatin M occurs during breast cancer progression. Cancer Res (2006) 1.20
The tumor suppressor Wnt inhibitory factor 1 is frequently methylated in nasopharyngeal and esophageal carcinomas. Lab Invest (2007) 1.19
Butyrate suppresses colonic inflammation through HDAC1-dependent Fas upregulation and Fas-mediated apoptosis of T cells. Am J Physiol Gastrointest Liver Physiol (2012) 1.18
Targeted bisulfite sequencing by solution hybrid selection and massively parallel sequencing. Nucleic Acids Res (2011) 1.15
DNMT1 knockout delivers a strong blow to genome stability and cell viability. Nat Genet (2007) 1.12
DNMT3B interacts with hSNF2H chromatin remodeling enzyme, HDACs 1 and 2, and components of the histone methylation system. Biochem Biophys Res Commun (2004) 1.11
A novel DNMT3B splice variant expressed in tumor and pluripotent cells modulates genomic DNA methylation patterns and displays altered DNA binding. Mol Cancer Res (2009) 1.10
Stealth technology: how Epstein-Barr virus utilizes DNA methylation to cloak itself from immune detection. Clin Immunol (2003) 1.09
An EBF3-mediated transcriptional program that induces cell cycle arrest and apoptosis. Cancer Res (2006) 1.08
Effects of chromatin structure on the enzymatic and DNA binding functions of DNA methyltransferases DNMT1 and Dnmt3a in vitro. Biochem Biophys Res Commun (2004) 1.08
Slow progressive conduction and contraction defects in loss of Nkx2-5 mice after cardiomyocyte terminal differentiation. Lab Invest (2009) 1.07
Comparative epigenomics of human and mouse mammary tumors. Genes Chromosomes Cancer (2009) 1.07
Invasion suppressor cystatin E/M (CST6): high-level cell type-specific expression in normal brain and epigenetic silencing in gliomas. Lab Invest (2008) 1.06
Rapid and transient recruitment of DNMT1 to DNA double-strand breaks is mediated by its interaction with multiple components of the DNA damage response machinery. Hum Mol Genet (2010) 1.06
Modulation of Dnmt3b function in vitro by interactions with Dnmt3L, Dnmt3a and Dnmt3b splice variants. Nucleic Acids Res (2011) 1.05
Potential advantages of DNA methyltransferase 1 (DNMT1)-targeted inhibition for cancer therapy. J Mol Med (Berl) (2007) 1.03
Doxorubicin inhibits DNMT1, resulting in conditional apoptosis. Mol Pharmacol (2004) 1.01
Histone deacetylase inhibitors for cancer therapy. Epigenetics (2006) 0.98
Distinct and overlapping control of 5-methylcytosine and 5-hydroxymethylcytosine by the TET proteins in human cancer cells. Genome Biol (2014) 0.93
Molecular modeling of inhibitors of human DNA methyltransferase with a crystal structure: discovery of a novel DNMT1 inhibitor. Adv Protein Chem Struct Biol (2012) 0.91
Epigenetic mechanisms and genome stability. Clin Epigenetics (2011) 0.89
The transglutaminase 2 gene is aberrantly hypermethylated in glioma. J Neurooncol (2010) 0.87
DMB (DNMT-magnetic beads) assay: measuring DNA methyltransferase activity in vitro. Methods Mol Biol (2004) 0.87
Epigenetic control of tumor suppression. Crit Rev Eukaryot Gene Expr (2007) 0.86
Dimethyl sulfoxide stimulates the catalytic activity of de novo DNA methyltransferase 3a (Dnmt3a) in vitro. Bioorg Chem (2004) 0.80