Published in Biochem Biophys Res Commun on May 28, 2004
DNA methylation inhibitor 5-Aza-2'-deoxycytidine induces reversible genome-wide DNA damage that is distinctly influenced by DNA methyltransferases 1 and 3B. Mol Cell Biol (2007) 2.47
The role of epigenetics in the pathology of diabetic complications. Am J Physiol Renal Physiol (2010) 1.83
DNA methylation and its basic function. Neuropsychopharmacology (2012) 1.76
Cancer cells express aberrant DNMT3B transcripts encoding truncated proteins. Oncogene (2007) 1.70
Direct interaction between DNA methyltransferase DIM-2 and HP1 is required for DNA methylation in Neurospora crassa. Mol Cell Biol (2008) 1.58
Isolation and characterization of a novel DNA methyltransferase complex linking DNMT3B with components of the mitotic chromosome condensation machinery. Nucleic Acids Res (2004) 1.44
ICF, an immunodeficiency syndrome: DNA methyltransferase 3B involvement, chromosome anomalies, and gene dysregulation. Autoimmunity (2008) 1.43
LSH cooperates with DNA methyltransferases to repress transcription. Mol Cell Biol (2007) 1.36
Physical and functional interaction of DNA methyltransferase 3A with Mbd3 and Brg1 in mouse lymphosarcoma cells. Cancer Res (2005) 1.17
Nucleosomes protect DNA from DNA methylation in vivo and in vitro. Nucleic Acids Res (2011) 1.08
Role of DNA methyltransferases in regulation of human ribosomal RNA gene transcription. J Biol Chem (2006) 1.06
miR-100 induces epithelial-mesenchymal transition but suppresses tumorigenesis, migration and invasion. PLoS Genet (2014) 1.05
SALL3 interacts with DNMT3A and shows the ability to inhibit CpG island methylation in hepatocellular carcinoma. Mol Cell Biol (2009) 1.02
Global heterochromatin loss: a unifying theory of aging? Epigenetics (2012) 0.95
The promise and failures of epigenetic therapies for cancer treatment. Cancer Treat Rev (2013) 0.93
Expression of methylation-related genes is associated with overall survival in patients with non-small cell lung cancer. Br J Cancer (2008) 0.90
DNA methyltransferase 3b preferentially associates with condensed chromatin. Nucleic Acids Res (2010) 0.90
Osterix and NO66 histone demethylase control the chromatin of Osterix target genes during osteoblast differentiation. J Bone Miner Res (2014) 0.87
Dexamethasone induces a putative repressor complex and chromatin modifications in the CRH promoter. Mol Endocrinol (2013) 0.85
De novo DNA methyltransferase DNMT3b interacts with NEDD8-modified proteins. J Biol Chem (2010) 0.81
Ectopic ERK expression induces phenotypic conversion of C10 cells and alters DNA methyltransferase expression. BMC Res Notes (2012) 0.81
Epigenetics of diabetic complications. Expert Rev Endocrinol Metab (2010) 0.80
DNA methyltransferases and TETs in the regulation of differentiation and invasiveness of extra-villous trophoblasts. Front Genet (2013) 0.79
Quantitative proteomic analysis of histone modifications in decitabine sensitive and resistant leukemia cell lines. Clin Proteomics (2016) 0.76
Allosteric control of mammalian DNA methyltransferases - a new regulatory paradigm. Nucleic Acids Res (2016) 0.76
Identification of proteins related to epigenetic regulation in the malignant transformation of aberrant karyotypic human embryonic stem cells by quantitative proteomics. PLoS One (2014) 0.75
Epigenetic silencing of downstream genes mediated by tandem orientation in lung cancer. Sci Rep (2017) 0.75
Substrate and functional diversity of lysine acetylation revealed by a proteomics survey. Mol Cell (2006) 11.38
Acetylation is indispensable for p53 activation. Cell (2008) 5.70
Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification. Cell (2011) 5.27
Jarid2/Jumonji coordinates control of PRC2 enzymatic activity and target gene occupancy in pluripotent cells. Cell (2009) 5.26
RalB GTPase-mediated activation of the IkappaB family kinase TBK1 couples innate immune signaling to tumor cell survival. Cell (2006) 5.08
Tumor suppression in the absence of p53-mediated cell-cycle arrest, apoptosis, and senescence. Cell (2012) 4.96
Lysine acetylation is a highly abundant and evolutionarily conserved modification in Escherichia coli. Mol Cell Proteomics (2008) 4.36
Chinese hamster ovary K2 cell lipid droplets appear to be metabolic organelles involved in membrane traffic. J Biol Chem (2003) 3.90
Distinctive roles of PHAP proteins and prothymosin-alpha in a death regulatory pathway. Science (2003) 3.59
JMJD6 is a histone arginine demethylase. Science (2007) 3.48
Lysine propionylation and butyrylation are novel post-translational modifications in histones. Mol Cell Proteomics (2007) 3.09
Protein acetylation microarray reveals that NuA4 controls key metabolic target regulating gluconeogenesis. Cell (2009) 2.99
Specific loss of histone H3 lysine 9 trimethylation and HP1gamma/cohesin binding at D4Z4 repeats is associated with facioscapulohumeral dystrophy (FSHD). PLoS Genet (2009) 2.90
CHD7 cooperates with PBAF to control multipotent neural crest formation. Nature (2010) 2.88
Identification of lysine succinylation as a new post-translational modification. Nat Chem Biol (2010) 2.87
The first identification of lysine malonylation substrates and its regulatory enzyme. Mol Cell Proteomics (2011) 2.83
Dynamic activity of lipid droplets: protein phosphorylation and GTP-mediated protein translocation. J Proteome Res (2007) 2.76
A tagging-via-substrate technology for detection and proteomics of farnesylated proteins. Proc Natl Acad Sci U S A (2004) 2.74
DNA methylation inhibitor 5-Aza-2'-deoxycytidine induces reversible genome-wide DNA damage that is distinctly influenced by DNA methyltransferases 1 and 3B. Mol Cell Biol (2007) 2.47
Brown remodeling of white adipose tissue by SirT1-dependent deacetylation of Pparγ. Cell (2012) 2.46
Integrated approach for manual evaluation of peptides identified by searching protein sequence databases with tandem mass spectra. J Proteome Res (2005) 2.27
SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell (2013) 2.17
Overview of the Alliance for Cellular Signaling. Nature (2002) 2.15
Acetylation of yeast AMPK controls intrinsic aging independently of caloric restriction. Cell (2011) 2.10
An intimate collaboration between peroxisomes and lipid bodies. J Cell Biol (2006) 2.04
A comprehensive synthetic genetic interaction network governing yeast histone acetylation and deacetylation. Genes Dev (2008) 2.01
Epigenomic profiling reveals novel and frequent targets of aberrant DNA methylation-mediated silencing in malignant glioma. Cancer Res (2006) 2.00
Lysine succinylation and lysine malonylation in histones. Mol Cell Proteomics (2012) 1.95
WNK1 and OSR1 regulate the Na+, K+, 2Cl- cotransporter in HeLa cells. Proc Natl Acad Sci U S A (2006) 1.90
Prevalence of prehypertension and hypertension in a Chinese rural area from 1991 to 2007. Hypertens Res (2010) 1.90
2D differential in-gel electrophoresis for the identification of esophageal scans cell cancer-specific protein markers. Mol Cell Proteomics (2002) 1.85
Proteome-wide prediction of acetylation substrates. Proc Natl Acad Sci U S A (2009) 1.81
Proteomic analysis of integral plasma membrane proteins. Anal Chem (2004) 1.78
DNA methylation in development and human disease. Mutat Res (2008) 1.74
Chromatin remodeling, histone modifications, and DNA methylation-how does it all fit together? J Cell Biochem (2002) 1.67
HDAC1 acetylation is linked to progressive modulation of steroid receptor-induced gene transcription. Mol Cell (2006) 1.67
DNA methyltransferase 3B (DNMT3B) mutations in ICF syndrome lead to altered epigenetic modifications and aberrant expression of genes regulating development, neurogenesis and immune function. Hum Mol Genet (2007) 1.65
Azacitidine induces demethylation of the Epstein-Barr virus genome in tumors. J Clin Oncol (2004) 1.65
Human DNA methyltransferase 1 is required for maintenance of the histone H3 modification pattern. J Biol Chem (2004) 1.64
Proteomics of human breast ductal carcinoma in situ. Cancer Res (2002) 1.62
Myosin light chain kinase and myosin phosphorylation effect frequency-dependent potentiation of skeletal muscle contraction. Proc Natl Acad Sci U S A (2005) 1.59
TAO kinases mediate activation of p38 in response to DNA damage. EMBO J (2007) 1.59
DNA methyltransferases, DNA damage repair, and cancer. Adv Exp Med Biol (2013) 1.57
Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways. Mol Cell Proteomics (2012) 1.54
Modification of de novo DNA methyltransferase 3a (Dnmt3a) by SUMO-1 modulates its interaction with histone deacetylases (HDACs) and its capacity to repress transcription. Nucleic Acids Res (2004) 1.52
Evaluation of ethanol-fixed, paraffin-embedded tissues for proteomic applications. Proteomics (2003) 1.50
An aPKC-exocyst complex controls paxillin phosphorylation and migration through localised JNK1 activation. PLoS Biol (2009) 1.48
Inactivation of Wnt inhibitory factor-1 (WIF1) expression by epigenetic silencing is a common event in breast cancer. Carcinogenesis (2006) 1.47
PTMap--a sequence alignment software for unrestricted, accurate, and full-spectrum identification of post-translational modification sites. Proc Natl Acad Sci U S A (2009) 1.46
DNA methylation: superior or subordinate in the epigenetic hierarchy? Genes Cancer (2011) 1.45
Isolation and characterization of a novel DNA methyltransferase complex linking DNMT3B with components of the mitotic chromosome condensation machinery. Nucleic Acids Res (2004) 1.44
DNMT3B interacts with constitutive centromere protein CENP-C to modulate DNA methylation and the histone code at centromeric regions. Hum Mol Genet (2009) 1.41
Impact of transradial coronary procedures on radial artery function. Angiology (2013) 1.41
Tetrandrine inhibits Wnt/β-catenin signaling and suppresses tumor growth of human colorectal cancer. Mol Pharmacol (2010) 1.40
14-3-3gamma binds to MDMX that is phosphorylated by UV-activated Chk1, resulting in p53 activation. EMBO J (2006) 1.40
Global identification of O-GlcNAc-modified proteins. Anal Chem (2006) 1.40
Contributions of the two accessory subunits, RNASEH2B and RNASEH2C, to the activity and properties of the human RNase H2 complex. Nucleic Acids Res (2008) 1.39
Autophosphorylation-dependent activation of human Mps1 is required for the spindle checkpoint. Proc Natl Acad Sci U S A (2007) 1.39
Phosphorylation-dependent 14-3-3 binding to LRRK2 is impaired by common mutations of familial Parkinson's disease. PLoS One (2011) 1.38
Molecular characterization of propionyllysines in non-histone proteins. Mol Cell Proteomics (2008) 1.33
A clean, more efficient method for in-solution digestion of protein mixtures without detergent or urea. J Proteome Res (2006) 1.33
Defective de novo methylation of viral and cellular DNA sequences in ICF syndrome cells. Hum Mol Genet (2002) 1.32
Proteomic analysis and identification of new biomarkers and therapeutic targets for invasive ovarian cancer. Proteomics (2002) 1.31
Preferential methylation of unmethylated DNA by Mammalian de novo DNA methyltransferase Dnmt3a. J Biol Chem (2002) 1.30
SIRT1 collaborates with ATM and HDAC1 to maintain genomic stability in neurons. Nat Neurosci (2013) 1.30
Coexpression of VEGF and angiopoietin-1 promotes angiogenesis and cardiomyocyte proliferation reduces apoptosis in porcine myocardial infarction (MI) heart. Proc Natl Acad Sci U S A (2011) 1.29
Mitochondrial phosphoproteome revealed by an improved IMAC method and MS/MS/MS. Mol Cell Proteomics (2007) 1.27
Linking DNA methyltransferases to epigenetic marks and nucleosome structure genome-wide in human tumor cells. Cell Rep (2012) 1.27
DNMT1 and DNMT3B modulate distinct polycomb-mediated histone modifications in colon cancer. Cancer Res (2009) 1.26
Role of KCNMA1 gene in breast cancer invasion and metastasis to brain. BMC Cancer (2009) 1.26
Identification and verification of lysine propionylation and butyrylation in yeast core histones using PTMap software. J Proteome Res (2009) 1.25
Chromatin-to-nucleoprotamine transition is controlled by the histone H2B variant TH2B. Genes Dev (2013) 1.24
ARD1 stabilization of TSC2 suppresses tumorigenesis through the mTOR signaling pathway. Sci Signal (2010) 1.22
Histone crotonylation specifically marks the haploid male germ cell gene expression program: post-meiotic male-specific gene expression. Bioessays (2011) 1.22
Epigenetic silencing of the tumor suppressor cystatin M occurs during breast cancer progression. Cancer Res (2006) 1.20
Complications in the assignment of 14 and 28 Da mass shift detected by mass spectrometry as in vivo methylation from endogenous proteins. Anal Chem (2008) 1.19
The tumor suppressor Wnt inhibitory factor 1 is frequently methylated in nasopharyngeal and esophageal carcinomas. Lab Invest (2007) 1.19
Mip1, an MEKK2-interacting protein, controls MEKK2 dimerization and activation. Mol Cell Biol (2005) 1.19
Butyrate suppresses colonic inflammation through HDAC1-dependent Fas upregulation and Fas-mediated apoptosis of T cells. Am J Physiol Gastrointest Liver Physiol (2012) 1.18
Identification of lysine succinylation substrates and the succinylation regulatory enzyme CobB in Escherichia coli. Mol Cell Proteomics (2013) 1.17
Identification and validation of eukaryotic aspartate and glutamate methylation in proteins. J Proteome Res (2008) 1.16
Targeted bisulfite sequencing by solution hybrid selection and massively parallel sequencing. Nucleic Acids Res (2011) 1.15
Tagging-via-substrate strategy for probing O-GlcNAc modified proteins. J Proteome Res (2005) 1.14
Diabetes-induced changes in the renal cortical proteome assessed with two-dimensional gel electrophoresis and mass spectrometry. Proteomics (2007) 1.13
DNMT1 knockout delivers a strong blow to genome stability and cell viability. Nat Genet (2007) 1.12
Stk40 links the pluripotency factor Oct4 to the Erk/MAPK pathway and controls extraembryonic endoderm differentiation. Proc Natl Acad Sci U S A (2010) 1.12
Selective enrichment of thiophosphorylated polypeptides as a tool for the analysis of protein phosphorylation. Mol Cell Proteomics (2003) 1.11
A novel DNMT3B splice variant expressed in tumor and pluripotent cells modulates genomic DNA methylation patterns and displays altered DNA binding. Mol Cancer Res (2009) 1.10
Detergent-free caveolae proteome suggests an interaction with ER and mitochondria. Proteomics (2006) 1.10
Stealth technology: how Epstein-Barr virus utilizes DNA methylation to cloak itself from immune detection. Clin Immunol (2003) 1.09
Strategic plan for lung vascular research: An NHLBI-ORDR Workshop Report. Am J Respir Crit Care Med (2010) 1.09
Wwp2-mediated ubiquitination of the RNA polymerase II large subunit in mouse embryonic pluripotent stem cells. Mol Cell Biol (2007) 1.08