Published in Prog Brain Res on January 01, 2004
A C. elegans model of nicotine-dependent behavior: regulation by TRP-family channels. Cell (2006) 2.68
Genetic variability in nicotinic acetylcholine receptors and nicotine addiction: converging evidence from human and animal research. Behav Brain Res (2008) 1.14
The nicotinic acetylcholine receptor CHRNA5/A3/B4 gene cluster: dual role in nicotine addiction and lung cancer. Prog Neurobiol (2010) 1.09
Activation and inhibition of mouse muscle and neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes. J Pharmacol Exp Ther (2010) 1.08
Regulation of synaptic transmission and plasticity by neuronal nicotinic acetylcholine receptors. Biochem Pharmacol (2007) 1.08
An autoradiographic survey of mouse brain nicotinic acetylcholine receptors defined by null mutants. Biochem Pharmacol (2011) 1.02
Alpha7 nicotinic acetylcholine receptors modulate motivation to self-administer nicotine: implications for smoking and schizophrenia. Neuropsychopharmacology (2011) 1.01
Alpha4* nicotinic receptors in preBotzinger complex mediate cholinergic/nicotinic modulation of respiratory rhythm. J Neurosci (2008) 1.00
α7 Nicotinic Receptor Agonists: Potential Therapeutic Drugs for Treatment of Cognitive Impairments in Schizophrenia and Alzheimer's Disease. Open Med Chem J (2010) 1.00
Biochemical and functional properties of distinct nicotinic acetylcholine receptors in the superior cervical ganglion of mice with targeted deletions of nAChR subunit genes. Eur J Neurosci (2010) 0.96
Selective deletion of the alpha5 subunit differentially affects somatic-dendritic versus axonally targeted nicotinic ACh receptors in mouse. J Physiol (2004) 0.94
Selectivity of ABT-089 for alpha4beta2* and alpha6beta2* nicotinic acetylcholine receptors in brain. Biochem Pharmacol (2009) 0.91
Modulation of the Ca2+ conductance of nicotinic acetylcholine receptors by Lypd6. Eur Neuropsychopharmacol (2009) 0.90
Multiple CNS nicotinic receptors mediate L-dopa-induced dyskinesias: studies with parkinsonian nicotinic receptor knockout mice. Biochem Pharmacol (2013) 0.90
Trace eyeblink conditioning is impaired in α7 but not in β2 nicotinic acetylcholine receptor knockout mice. Front Behav Neurosci (2010) 0.89
The Ferrier Lecture 1998. The molecular biology of consciousness investigated with genetically modified mice. Philos Trans R Soc Lond B Biol Sci (2006) 0.86
Brain activation by short-term nicotine exposure in anesthetized wild-type and beta2-nicotinic receptors knockout mice: a BOLD fMRI study. Psychopharmacology (Berl) (2008) 0.79
Activities of nicotinic acetylcholine receptors modulate neurotransmission and synaptic architecture. Neural Regen Res (2014) 0.76
The detrimental danger of Water-Pipe (Hookah) transcends the hazardous consequences of general health to the driving behavior. J Transl Med (2012) 0.76
α4β2 nicotinic acetylcholine receptors in the early postnatal mouse superior cervical ganglion. Dev Neurobiol (2011) 0.75
X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation. Nature (2008) 5.77
Conscious, preconscious, and subliminal processing: a testable taxonomy. Trends Cogn Sci (2006) 4.66
Experimental and theoretical approaches to conscious processing. Neuron (2011) 4.28
Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system. Nat Rev Drug Discov (2009) 3.26
A prokaryotic proton-gated ion channel from the nicotinic acetylcholine receptor family. Nature (2006) 3.04
X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel. Nature (2011) 3.00
Subunit composition of functional nicotinic receptors in dopaminergic neurons investigated with knock-out mice. J Neurosci (2003) 2.85
A neuronal network model linking subjective reports and objective physiological data during conscious perception. Proc Natl Acad Sci U S A (2003) 2.79
Hierarchical control of dopamine neuron-firing patterns by nicotinic receptors. Neuron (2006) 2.69
Normal mode analysis suggests a quaternary twist model for the nicotinic receptor gating mechanism. Biophys J (2005) 2.33
The diversity of subunit composition in nAChRs: evolutionary origins, physiologic and pharmacologic consequences. J Neurobiol (2002) 2.20
Distribution and pharmacology of alpha 6-containing nicotinic acetylcholine receptors analyzed with mutant mice. J Neurosci (2002) 2.05
Nicotine upregulates its own receptors through enhanced intracellular maturation. Neuron (2005) 1.89
One-microsecond molecular dynamics simulation of channel gating in a nicotinic receptor homologue. Proc Natl Acad Sci U S A (2010) 1.81
Models of the extracellular domain of the nicotinic receptors and of agonist- and Ca2+-binding sites. Proc Natl Acad Sci U S A (2002) 1.78
The beta2 but not alpha7 subunit of the nicotinic acetylcholine receptor is required for nicotine-conditioned place preference in mice. Psychopharmacology (Berl) (2006) 1.76
Structure and pharmacology of pentameric receptor channels: from bacteria to brain. Structure (2012) 1.69
Molecular tuning of fast gating in pentameric ligand-gated ion channels. Proc Natl Acad Sci U S A (2005) 1.58
A neuronal model of predictive coding accounting for the mismatch negativity. J Neurosci (2012) 1.48
Ongoing spontaneous activity controls access to consciousness: a neuronal model for inattentional blindness. PLoS Biol (2005) 1.47
Distinct contributions of nicotinic acetylcholine receptor subunit alpha4 and subunit alpha6 to the reinforcing effects of nicotine. Proc Natl Acad Sci U S A (2011) 1.44
Executive and social behaviors under nicotinic receptor regulation. Proc Natl Acad Sci U S A (2003) 1.44
Altered map of visual space in the superior colliculus of mice lacking early retinal waves. J Neurosci (2005) 1.38
Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation. Proc Natl Acad Sci U S A (2013) 1.32
Implications of the quaternary twist allosteric model for the physiology and pathology of nicotinic acetylcholine receptors. Proc Natl Acad Sci U S A (2006) 1.32
Experimentally based model of a complex between a snake toxin and the alpha 7 nicotinic receptor. Proc Natl Acad Sci U S A (2002) 1.32
Conformational selection or induced fit? 50 years of debate resolved. F1000 Biol Rep (2011) 1.31
Pore conformations and gating mechanism of a Cys-loop receptor. Proc Natl Acad Sci U S A (2005) 1.31
Nicotine and serotonin in immune regulation and inflammatory processes: a perspective. J Leukoc Biol (2006) 1.22
An H-bond between two residues from different loops of the acetylcholine binding site contributes to the activation mechanism of nicotinic receptors. EMBO J (2003) 1.19
Localization of [3H]nicotine, [3H]cytisine, [3H]epibatidine, and [125I]alpha-bungarotoxin binding sites in the brain of Macaca mulatta. J Comp Neurol (2003) 1.18
Monitoring protein interactions in the living cell through the fluorescence decays of the cyan fluorescent protein. Chemphyschem (2006) 1.18
Rapsyn escorts the nicotinic acetylcholine receptor along the exocytic pathway via association with lipid rafts. J Neurosci (2002) 1.17
Nicotine activates immature "silent" connections in the developing hippocampus. Proc Natl Acad Sci U S A (2003) 1.17
An extracellular protein microdomain controls up-regulation of neuronal nicotinic acetylcholine receptors by nicotine. J Biol Chem (2004) 1.15
A gating mechanism of pentameric ligand-gated ion channels. Proc Natl Acad Sci U S A (2013) 1.15
Intracellular complexes of the beta2 subunit of the nicotinic acetylcholine receptor in brain identified by proteomics. Proc Natl Acad Sci U S A (2007) 1.15
α-Conotoxin BuIA[T5A;P6O]: a novel ligand that discriminates between α6ß4 and α6ß2 nicotinic acetylcholine receptors and blocks nicotine-stimulated norepinephrine release. FASEB J (2010) 1.12
Nicotinic modulation of network and synaptic transmission in the immature hippocampus investigated with genetically modified mice. J Physiol (2006) 1.12
Prefrontal nicotinic receptors control novel social interaction between mice. FASEB J (2011) 1.11
Alterations of cortical pyramidal neurons in mice lacking high-affinity nicotinic receptors. Proc Natl Acad Sci U S A (2010) 1.10
Interplay of beta2* nicotinic receptors and dopamine pathways in the control of spontaneous locomotion. Proc Natl Acad Sci U S A (2008) 1.08
Reinforcing effects of nicotine microinjections into the ventral tegmental area of mice: dependence on cholinergic nicotinic and dopaminergic D1 receptors. Neuropharmacology (2006) 1.08
Long-term effects of chronic nicotine exposure on brain nicotinic receptors. Proc Natl Acad Sci U S A (2007) 1.08
Perinatal exposure to nicotine causes deficits associated with a loss of nicotinic receptor function. Proc Natl Acad Sci U S A (2005) 1.08
The emergence of human consciousness: from fetal to neonatal life. Pediatr Res (2009) 1.04
Electron microscopic evidence for nucleation and growth of 3D acetylcholine receptor microcrystals in structured lipid-detergent matrices. Proc Natl Acad Sci U S A (2003) 1.03
Beta2-containing nicotinic receptors contribute to the organization of sleep and regulate putative micro-arousals in mice. J Neurosci (2004) 1.02
Nicotinic receptors regulate the survival of newborn neurons in the adult olfactory bulb. Proc Natl Acad Sci U S A (2004) 1.01
Nicotine enhances intracellular nicotinic receptor maturation: a novel mechanism of neural plasticity? J Physiol Paris (2006) 1.01
A chimera encoding the fusion of an acetylcholine-binding protein to an ion channel is stabilized in a state close to the desensitized form of ligand-gated ion channels. C R Biol (2005) 1.01
Monoamine oxidase inhibitors allow locomotor and rewarding responses to nicotine. Neuropsychopharmacology (2005) 1.00
{alpha}7 nicotinic acetylcholine receptor regulates airway epithelium differentiation by controlling basal cell proliferation. Am J Pathol (2009) 0.97
Live imaging of neural structure and function by fibred fluorescence microscopy. EMBO Rep (2006) 0.96
Analysis of the cellular expression pattern of beta-CGRP in alpha-CGRP-deficient mice. J Comp Neurol (2004) 0.96
Nicotine differentially activates inhibitory and excitatory neurons in the dorsal spinal cord. Pain (2004) 0.96
Allosteric transitions of Torpedo acetylcholine receptor in lipids, detergent and amphipols: molecular interactions vs. physical constraints. FEBS Lett (2002) 0.96
Behavioral sequence analysis reveals a novel role for beta2* nicotinic receptors in exploration. PLoS Comput Biol (2008) 0.95
Expression of mutant Ets protein at the neuromuscular synapse causes alterations in morphology and gene expression. EMBO Rep (2002) 0.95
Nicotinic receptors regulate B lymphocyte activation and immune response. Eur J Pharmacol (2005) 0.93
Inhibition of both alpha7* and beta2* nicotinic acetylcholine receptors is necessary to prevent development of sensitization to cocaine-elicited increases in extracellular dopamine levels in the ventral striatum. Psychopharmacology (Berl) (2006) 0.93
A neurocomputational hypothesis for nicotine addiction. Proc Natl Acad Sci U S A (2006) 0.92
beta 2 nicotinic acetylcholine receptor subunit modulates protective responses to stress: A receptor basis for sleep-disordered breathing after nicotine exposure. Proc Natl Acad Sci U S A (2002) 0.92
14-3-3 gamma associates with muscle specific kinase and regulates synaptic gene transcription at vertebrate neuromuscular synapse. Proc Natl Acad Sci U S A (2004) 0.92
Biosynthesis of riboflavin: 6,7-dimethyl-8-ribityllumazine synthase of Schizosaccharomyces pombe. Eur J Biochem (2002) 0.91
Alpha7-nicotinic receptors modulate nicotine-induced reinforcement and extracellular dopamine outflow in the mesolimbic system in mice. Psychopharmacology (Berl) (2011) 0.91
Attention-deficit/hyperactivity disorder: a plausible mouse model? Acta Paediatr (2006) 0.91
Mechanism of Cl- selection by a glutamate-gated chloride (GluCl) receptor revealed through mutations in the selectivity filter. J Biol Chem (2006) 0.90
Functional nicotinic acetylcholine receptors are expressed in B lymphocyte-derived cell lines. Mol Pharmacol (2003) 0.89
Selective activation of central subtypes of the nicotinic acetylcholine receptor has opposite effects on neonatal excitotoxic brain injuries. FASEB J (2002) 0.89
A versatile system for the neuronal subtype specific expression of lentiviral vectors. FASEB J (2009) 0.89
Object memory in young and aged mice after sevoflurane anaesthesia. Neuroreport (2009) 0.88
Phosphorylation-elicited quaternary changes of GA binding protein in transcriptional activation. Mol Cell Biol (2003) 0.86
Transcription in neuromuscular junction formation: who turns on whom? J Neurocytol (2004) 0.86
A non-radioactive ligand-binding assay for detection of cyanobacterial anatoxins using Torpedo electrocyte membranes. Toxicon (2008) 0.86
The concept of allosteric modulation: an overview. Drug Discov Today Technol (2013) 0.85
The role of nicotinic acetylcholine receptors in lymphocyte development. J Neuroimmunol (2005) 0.84
Distinct subcellular targeting of fluorescent nicotinic alpha 3 beta 4 and serotoninergic 5-HT3A receptors in hippocampal neurons. Eur J Neurosci (2004) 0.84
Relationships between structural dynamics and functional kinetics in oligomeric membrane receptors. Biophys J (2010) 0.84
Rational understanding of nicotinic receptors drug binding. Curr Top Med Chem (2004) 0.84
Altered paralimbic interaction in behavioral addiction. Proc Natl Acad Sci U S A (2013) 0.83
Reduction of withdrawal signs after chronic nicotine exposure of alpha-calcitonin gene-related peptide knock-out mice. Neurosci Lett (2004) 0.82
Deciding between conflicting motivations: what mice make of their prefrontal cortex. Behav Brain Res (2011) 0.82
Long-term exposure to nicotine modulates the level and activity of acetylcholine receptors in white blood cells of smokers and model mice. Mol Pharmacol (2004) 0.81
Modulation of the mouse prefrontal cortex activation by neuronal nicotinic receptors during novelty exploration but not by exploration of a familiar environment. Cereb Cortex (2011) 0.80
Basic consciousness of the newborn. Semin Perinatol (2010) 0.80
Allosteric regulation of pentameric ligand-gated ion channels: an emerging mechanistic perspective. Channels (Austin) (2014) 0.80
Chronic nicotine exposure has dissociable behavioural effects on control and beta2-/- mice. Behav Genet (2008) 0.79
Antibodies against extracellular domains of α4 and α7 subunits alter the levels of nicotinic receptors in the mouse brain and affect memory: possible relevance to Alzheimer's pathology. J Alzheimers Dis (2011) 0.79
Functional organization and conformational dynamics of the nicotinic receptor: a plausible structural interpretation of myasthenic mutations. Ann N Y Acad Sci (2008) 0.79
Docking of alpha-cobratoxin suggests a basal conformation of the nicotinic receptor. Biochem Biophys Res Commun (2007) 0.79
Acquisition and performance of delayed-response tasks: a neural network model. Cereb Cortex (2004) 0.78
Loss of high-affinity nicotinic receptors increases the vulnerability to excitotoxic lesion and decreases the positive effects of an enriched environment. FASEB J (2007) 0.78
Intermediate closed state for glycine receptor function revealed by cysteine cross-linking. Proc Natl Acad Sci U S A (2013) 0.78
Regional differential effects of chronic nicotine on brain alpha 4-containing and alpha 6-containing receptors. Neuroreport (2008) 0.77
Abnormal response of dopaminergic neurons to nicotine without perturbation of nicotinic receptors in alphaCGRP knock-out mice. Brain Res (2008) 0.77
Identification of two critical residues within the Cys-loop sequence that determine fast-gating kinetics in a pentameric ligand-gated ion channel. J Mol Neurosci (2006) 0.76
Sevoflurane anesthesia alters exploratory and anxiety-like behavior in mice lacking the beta2 nicotinic acetylcholine receptor subunit. Anesthesiology (2008) 0.75
Immunoreactive Calcitonin Gene-Related Peptide, Vasoactive Intestinal Polypeptide, and Somatostatin in Developing Chicken Spinal Cord Motoneurons. Eur J Neurosci (1989) 0.75