Published in J Comp Neurol on November 04, 2002
CD81 gene defect in humans disrupts CD19 complex formation and leads to antibody deficiency. J Clin Invest (2010) 1.79
Characterization of mice lacking the tetraspanin superfamily member CD151. Mol Cell Biol (2004) 1.57
Beta 1-integrins are required for hippocampal AMPA receptor-dependent synaptic transmission, synaptic plasticity, and working memory. J Neurosci (2006) 1.42
Dynamic regulation of a GPCR-tetraspanin-G protein complex on intact cells: central role of CD81 in facilitating GPR56-Galpha q/11 association. Mol Biol Cell (2004) 1.36
DHHC2 affects palmitoylation, stability, and functions of tetraspanins CD9 and CD151. Mol Biol Cell (2008) 1.19
Building of the tetraspanin web: distinct structural domains of CD81 function in different cellular compartments. Mol Cell Biol (2006) 1.17
Tetraspanins in viral infections: a fundamental role in viral biology? J Virol (2005) 1.16
Deletion or Inhibition of the Oxygen Sensor PHD1 Protects against Ischemic Stroke via Reprogramming of Neuronal Metabolism. Cell Metab (2016) 1.05
Deficiency of the tetraspanin CD63 associated with kidney pathology but normal lysosomal function. Mol Cell Biol (2008) 1.04
Progesterone synthesis in the nervous system: implications for myelination and myelin repair. Front Neurosci (2012) 0.95
Aggrecan is expressed by embryonic brain glia and regulates astrocyte development. Dev Biol (2008) 0.95
Glioblastoma inhibition by cell surface immunoglobulin protein EWI-2, in vitro and in vivo. Neoplasia (2009) 0.90
Structural basis of ligand interactions of the large extracellular domain of tetraspanin CD81. J Virol (2012) 0.90
Identification of novel cell-adhesion molecules in peripheral nerves using a signal-sequence trap. Neuron Glia Biol (2006) 0.88
Identification of proteins involved in neural progenitor cell targeting of gliomas. BMC Cancer (2009) 0.87
Exosomes function in cell-cell communication during brain circuit development. Curr Opin Neurobiol (2013) 0.86
The tetraspanin CD81 protein increases melanoma cell motility by up-regulating metalloproteinase MT1-MMP expression through the pro-oncogenic Akt-dependent Sp1 activation signaling pathways. J Biol Chem (2014) 0.85
The tetraspanin KAI1/CD82 is expressed by late-lineage oligodendrocyte precursors and may function to restrict precursor migration and promote oligodendrocyte differentiation and myelination. J Neurosci (2009) 0.85
The extracellular δ-domain is essential for the formation of CD81 tetraspanin webs. Biophys J (2014) 0.84
Increased density of retinal pigment epithelium in cd81-/- mice. J Cell Biochem (2004) 0.83
Kv1.1-dependent control of hippocampal neuron number as revealed by mosaic analysis with double markers. J Physiol (2012) 0.80
Tetraspanins and Transmembrane Adaptor Proteins As Plasma Membrane Organizers-Mast Cell Case. Front Cell Dev Biol (2016) 0.78
Age dependent forebrain structural changes in mice deficient in the autism associated gene Met tyrosine kinase. Neuroimage Clin (2012) 0.78
Imaging whole-brain cytoarchitecture of mouse with MRI-based quantitative susceptibility mapping. Neuroimage (2016) 0.77
The effects of a CD81 null mutation on retinal pigment epithelium in mice. Neurochem Res (2010) 0.77
Tspan2: a tetraspanin protein involved in oligodendrogenesis and cancer metastasis. Biochem Soc Trans (2017) 0.75
The Emerging Role of Tetraspanins in the Proteolytic Processing of the Amyloid Precursor Protein. Front Mol Neurosci (2016) 0.75
Complex trait analysis of gene expression uncovers polygenic and pleiotropic networks that modulate nervous system function. Nat Genet (2005) 10.03
Computational identification of Drosophila microRNA genes. Genome Biol (2003) 9.86
The Collaborative Cross, a community resource for the genetic analysis of complex traits. Nat Genet (2004) 9.37
Uncovering regulatory pathways that affect hematopoietic stem cell function using 'genetical genomics'. Nat Genet (2005) 6.91
Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice. Nat Immunol (2007) 6.67
The neuroscience information framework: a data and knowledge environment for neuroscience. Neuroinformatics (2008) 4.60
A high-resolution single nucleotide polymorphism genetic map of the mouse genome. PLoS Biol (2006) 4.57
Mitonuclear protein imbalance as a conserved longevity mechanism. Nature (2013) 4.18
WebQTL: web-based complex trait analysis. Neuroinformatics (2003) 4.10
The nature and identification of quantitative trait loci: a community's view. Nat Rev Genet (2003) 3.96
A new set of BXD recombinant inbred lines from advanced intercross populations in mice. BMC Genet (2004) 3.74
PONDR-FIT: a meta-predictor of intrinsically disordered amino acids. Biochim Biophys Acta (2010) 3.62
The Collaborative Cross at Oak Ridge National Laboratory: developing a powerful resource for systems genetics. Mamm Genome (2008) 3.52
Results and harmonization guidelines from two large-scale international Elispot proficiency panels conducted by the Cancer Vaccine Consortium (CVC/SVI). Cancer Immunol Immunother (2007) 3.16
Genetic dissection of complex and quantitative traits: from fantasy to reality via a community effort. Mamm Genome (2002) 3.02
"MIATA"-minimal information about T cell assays. Immunity (2009) 2.90
WebQTL: rapid exploratory analysis of gene expression and genetic networks for brain and behavior. Nat Neurosci (2004) 2.86
Hepatocyte CD81 is required for Plasmodium falciparum and Plasmodium yoelii sporozoite infectivity. Nat Med (2002) 2.46
Recommendations from the iSBTc-SITC/FDA/NCI Workshop on Immunotherapy Biomarkers. Clin Cancer Res (2011) 2.44
Mapping the genetic architecture of complex traits in experimental populations. Bioinformatics (2007) 2.27
Towards effective and rewarding data sharing. Neuroinformatics (2003) 2.24
Maximizing the retention of antigen specific lymphocyte function after cryopreservation. J Immunol Methods (2005) 2.16
Genetic correlates of gene expression in recombinant inbred strains: a relational model system to explore neurobehavioral phenotypes. Neuroinformatics (2003) 2.09
Host genetic variation affects resistance to infection with a highly pathogenic H5N1 influenza A virus in mice. J Virol (2009) 2.08
Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. J Neurosci (2005) 2.05
The perplexing paradox of paraquat: the case for host-based susceptibility and postulated neurodegenerative effects. J Biochem Mol Toxicol (2014) 2.03
Expression of the human germinal center-associated lymphoma (HGAL) protein, a new marker of germinal center B-cell derivation. Blood (2005) 1.99
PolymiRTS Database: linking polymorphisms in microRNA target sites with complex traits. Nucleic Acids Res (2006) 1.96
Combined expression trait correlations and expression quantitative trait locus mapping. PLoS Genet (2006) 1.93
The CD81 partner EWI-2wint inhibits hepatitis C virus entry. PLoS One (2008) 1.86
Natural variation and genetic covariance in adult hippocampal neurogenesis. Proc Natl Acad Sci U S A (2006) 1.81
Quantitative trait locus analysis using recombinant inbred intercrosses: theoretical and empirical considerations. Genetics (2005) 1.80
CD81 gene defect in humans disrupts CD19 complex formation and leads to antibody deficiency. J Clin Invest (2010) 1.79
Metabolic networks of longevity. Cell (2010) 1.79
Apoptosis and other immune biomarkers predict influenza vaccine responsiveness. Mol Syst Biol (2013) 1.75
Phenotypic and molecular characterization of Madurella pseudomycetomatis sp. nov., a novel opportunistic fungus possibly causing black-grain mycetoma. J Clin Microbiol (2009) 1.71
How replicable are mRNA expression QTL? Mamm Genome (2006) 1.71
Performance of plate-based cytokine flow cytometry with automated data analysis. BMC Immunol (2003) 1.66
Dissection of a QTL hotspot on mouse distal chromosome 1 that modulates neurobehavioral phenotypes and gene expression. PLoS Genet (2008) 1.64
Strong cell-mediated immune responses are associated with the maintenance of low-level viremia in antiretroviral-treated individuals with drug-resistant human immunodeficiency virus type 1. J Infect Dis (2004) 1.58
Dynamics of CD4 and CD8 T cell responses to cytomegalovirus in healthy human donors. J Infect Dis (2002) 1.58
Murine gut microbiota is defined by host genetics and modulates variation of metabolic traits. PLoS One (2012) 1.58
Standardization and optimization of multiparameter intracellular cytokine staining. Cytometry A (2008) 1.53
Persistent and selective deficiency of CD4+ T cell immunity to cytomegalovirus in immunocompetent young children. J Immunol (2004) 1.52
Strain differences in stress responsivity are associated with divergent amygdala gene expression and glutamate-mediated neuronal excitability. J Neurosci (2010) 1.49
Systems genetics of metabolism: the use of the BXD murine reference panel for multiscalar integration of traits. Cell (2012) 1.48
Integrative genetic analysis of transcription modules: towards filling the gap between genetic loci and inherited traits. Hum Mol Genet (2005) 1.46
Gene expression in the mouse eye: an online resource for genetics using 103 strains of mice. Mol Vis (2009) 1.44
Inferring gene transcriptional modulatory relations: a genetical genomics approach. Hum Mol Genet (2005) 1.43
Variation in mouse basolateral amygdala volume is associated with differences in stress reactivity and fear learning. Neuropsychopharmacology (2008) 1.43
Identification of a Chr 11 quantitative trait locus that modulates proliferation in the rostral migratory stream of the adult mouse brain. Eur J Neurosci (2010) 1.42
Reduced fertility of female mice lacking CD81. Dev Biol (2005) 1.41
The p47 GTPases Iigp2 and Irgb10 regulate innate immunity and inflammation to murine Chlamydia psittaci infection. J Immunol (2007) 1.40
A strategy for the integration of QTL, gene expression, and sequence analyses. Mamm Genome (2003) 1.38
CD81-dependent binding of hepatitis C virus E1E2 heterodimers. J Virol (2003) 1.38
The Diasporin Pathway: a tumor progression-related transcriptional network that predicts breast cancer survival. Clin Exp Metastasis (2008) 1.36
Genetics of the hippocampal transcriptome in mouse: a systematic survey and online neurogenomics resource. Front Neurosci (2009) 1.36
Informatics center for mouse genomics: the dissection of complex traits of the nervous system. Neuroinformatics (2003) 1.34
Development and dynamics of robust T-cell responses to CML under imatinib treatment. Blood (2008) 1.34
Genome Reshuffling for Advanced Intercross Permutation (GRAIP): simulation and permutation for advanced intercross population analysis. PLoS One (2008) 1.33
Genome-level analysis of genetic regulation of liver gene expression networks. Hepatology (2007) 1.29
Dysfunction of simian immunodeficiency virus/simian human immunodeficiency virus-induced IL-2 expression by central memory CD4+ T lymphocytes. J Immunol (2005) 1.29
Genetic dissection of acute ethanol responsive gene networks in prefrontal cortex: functional and mechanistic implications. PLoS One (2012) 1.29
Measurement of refractive state and deprivation myopia in two strains of mice. Optom Vis Sci (2004) 1.27
The PhenoGen informatics website: tools for analyses of complex traits. BMC Genet (2007) 1.25
Expression of human CD81 differently affects host cell susceptibility to malaria sporozoites depending on the Plasmodium species. Cell Microbiol (2006) 1.25
Quality assurance of intracellular cytokine staining assays: analysis of multiple rounds of proficiency testing. J Immunol Methods (2010) 1.24
The tetraspanin CD81 is necessary for partitioning of coligated CD19/CD21-B cell antigen receptor complexes into signaling-active lipid rafts. J Immunol (2004) 1.23
High susceptibility to experimental myopia in a mouse model with a retinal on pathway defect. Invest Ophthalmol Vis Sci (2008) 1.22
The tetraspanin CD81 regulates the expression of CD19 during B cell development in a postendoplasmic reticulum compartment. J Immunol (2003) 1.21
Female-biased expression of long non-coding RNAs in domains that escape X-inactivation in mouse. BMC Genomics (2010) 1.19
Analysis of the frequencies and of the memory T cell phenotypes of human CD8+ T cells specific for influenza A viruses. J Infect Dis (2003) 1.19
Protective immunity to cytomegalovirus (CMV) retinitis in AIDS is associated with CMV-specific T cells that express interferon- gamma and interleukin-2 and have a CD8+ cell early maturational phenotype. J Infect Dis (2006) 1.19
Building of the tetraspanin web: distinct structural domains of CD81 function in different cellular compartments. Mol Cell Biol (2006) 1.17
Genetic control of sensitivity to hippocampal cell death induced by kainic acid: a quantitative trait loci analysis. J Comp Neurol (2004) 1.15
Multiple genes on chromosome 7 regulate dopaminergic amacrine cell number in the mouse retina. Invest Ophthalmol Vis Sci (2009) 1.15
Functional T cell responses to tumor antigens in breast cancer patients have a distinct phenotype and cytokine signature. J Immunol (2007) 1.14
Multicolor flow cytometric analysis in SIV-infected rhesus macaque. Methods Cell Biol (2004) 1.13
Genetic dissection of behavioral flexibility: reversal learning in mice. Biol Psychiatry (2011) 1.12
Multiparameter flow cytometry monitoring of T cell responses. Methods Mol Biol (2009) 1.11
Cell-free production of scFv fusion proteins: an efficient approach for personalized lymphoma vaccines. Blood (2006) 1.11
Immune responses in the draining lymph nodes against cancer: implications for immunotherapy. Cancer Metastasis Rev (2006) 1.11
Primary hepatocytes of Tupaia belangeri as a potential model for hepatitis C virus infection. J Clin Invest (2002) 1.11
Detection, validation, and downstream analysis of allelic variation in gene expression. Genetics (2009) 1.10
Recognition of native hepatitis C virus E1E2 heterodimers by a human monoclonal antibody. J Virol (2003) 1.09
IL-10-producing regulatory B10 cells ameliorate collagen-induced arthritis via suppressing Th17 cell generation. Am J Pathol (2012) 1.09
The genetic control of neocortex volume and covariation with neocortical gene expression in mice. BMC Neurosci (2009) 1.07
Epigenetic changes in tumor Fas levels determine immune escape and response to therapy. Cancer Cell (2002) 1.06
Engagement of CD81 induces ezrin tyrosine phosphorylation and its cellular redistribution with filamentous actin. J Cell Sci (2009) 1.05
Critical role of CD81 in cognate T-B cell interactions leading to Th2 responses. Int Immunol (2002) 1.05
Weighting by heritability for detection of quantitative trait loci with microarray estimates of gene expression. Genome Biol (2005) 1.05
Genetic modulation of horizontal cell number in the mouse retina. Proc Natl Acad Sci U S A (2011) 1.05
Archaic chaos: intrinsically disordered proteins in Archaea. BMC Syst Biol (2010) 1.05
Dopamine D2 receptor binding, Drd2 expression and the number of dopamine neurons in the BXD recombinant inbred series: genetic relationships to alcohol and other drug associated phenotypes. Alcohol Clin Exp Res (2003) 1.05
Differential response of C57BL/6J mouse and DBA/2J mouse to optic nerve crush. BMC Neurosci (2009) 1.04
Combining gene expression QTL mapping and phenotypic spectrum analysis to uncover gene regulatory relationships. Mamm Genome (2006) 1.04
An unbiased systems genetics approach to mapping genetic loci modulating susceptibility to severe streptococcal sepsis. PLoS Pathog (2008) 1.04
Complex control of GABA(A) receptor subunit mRNA expression: variation, covariation, and genetic regulation. PLoS One (2012) 1.04
An integrative genomics strategy for systematic characterization of genetic loci modulating phenotypes. Hum Mol Genet (2007) 1.03
Deconvoluting post-transplant immunity: cell subset-specific mapping reveals pathways for activation and expansion of memory T, monocytes and B cells. PLoS One (2010) 1.03