PubRank

Peter E Wright

Author PubWeight™ 173.44‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Intrinsically unstructured proteins and their functions. Nat Rev Mol Cell Biol 2005 17.63
2 The dynamic energy landscape of dihydrofolate reductase catalysis. Science 2006 7.55
3 The role of dynamic conformational ensembles in biomolecular recognition. Nat Chem Biol 2009 7.36
4 Coupling of folding and binding for unstructured proteins. Curr Opin Struct Biol 2002 6.53
5 Mechanism of coupled folding and binding of an intrinsically disordered protein. Nature 2007 6.26
6 PRAK is essential for ras-induced senescence and tumor suppression. Cell 2007 4.30
7 Structure, dynamics, and catalytic function of dihydrofolate reductase. Annu Rev Biophys Biomol Struct 2004 3.42
8 Recognition of the mRNA AU-rich element by the zinc finger domain of TIS11d. Nat Struct Mol Biol 2004 3.39
9 A dynamic knockout reveals that conformational fluctuations influence the chemical step of enzyme catalysis. Science 2011 3.19
10 An NMR perspective on enzyme dynamics. Chem Rev 2006 3.11
11 Structural basis for Hif-1 alpha /CBP recognition in the cellular hypoxic response. Proc Natl Acad Sci U S A 2002 2.97
12 Mutual synergistic folding in recruitment of CBP/p300 by p160 nuclear receptor coactivators. Nature 2002 2.78
13 Unfolded proteins and protein folding studied by NMR. Chem Rev 2004 2.71
14 Classification of intrinsically disordered regions and proteins. Chem Rev 2014 2.48
15 Defining the role of active-site loop fluctuations in dihydrofolate reductase catalysis. Proc Natl Acad Sci U S A 2005 2.21
16 Solution structure of the KIX domain of CBP bound to the transactivation domain of c-Myb. J Mol Biol 2004 1.83
17 Cooperativity in transcription factor binding to the coactivator CREB-binding protein (CBP). The mixed lineage leukemia protein (MLL) activation domain binds to an allosteric site on the KIX domain. J Biol Chem 2002 1.80
18 Structural basis for cooperative transcription factor binding to the CBP coactivator. J Mol Biol 2005 1.75
19 Structure of the Escherichia coli quorum sensing protein SdiA: activation of the folding switch by acyl homoserine lactones. J Mol Biol 2005 1.74
20 Conformational changes in the active site loops of dihydrofolate reductase during the catalytic cycle. Biochemistry 2004 1.72
21 Insights into the structure and dynamics of unfolded proteins from nuclear magnetic resonance. Adv Protein Chem 2002 1.71
22 Modulation of allostery by protein intrinsic disorder. Nature 2013 1.69
23 Structural characterization of unfolded states of apomyoglobin using residual dipolar couplings. J Mol Biol 2004 1.68
24 Roles of phosphorylation and helix propensity in the binding of the KIX domain of CREB-binding protein by constitutive (c-Myb) and inducible (CREB) activators. J Biol Chem 2002 1.61
25 Solution structure of the Hdm2 C2H2C4 RING, a domain critical for ubiquitination of p53. J Mol Biol 2006 1.61
26 Effect of cofactor binding and loop conformation on side chain methyl dynamics in dihydrofolate reductase. Biochemistry 2004 1.59
27 Biochemistry. How do proteins interact? Science 2008 1.58
28 Millisecond timescale fluctuations in dihydrofolate reductase are exquisitely sensitive to the bound ligands. Proc Natl Acad Sci U S A 2010 1.53
29 Mapping long-range contacts in a highly unfolded protein. J Mol Biol 2002 1.49
30 Cooperative regulation of p53 by modulation of ternary complex formation with CBP/p300 and HDM2. Proc Natl Acad Sci U S A 2009 1.48
31 The role of hydrophobic interactions in initiation and propagation of protein folding. Proc Natl Acad Sci U S A 2006 1.42
32 Interaction of the TAZ1 domain of the CREB-binding protein with the activation domain of CITED2: regulation by competition between intrinsically unstructured ligands for non-identical binding sites. J Biol Chem 2003 1.40
33 Graded enhancement of p53 binding to CREB-binding protein (CBP) by multisite phosphorylation. Proc Natl Acad Sci U S A 2010 1.39
34 Structure of the Wilms tumor suppressor protein zinc finger domain bound to DNA. J Mol Biol 2007 1.39
35 Mapping the interactions of the p53 transactivation domain with the KIX domain of CBP. Biochemistry 2009 1.35
36 Molecular hinges in protein folding: the urea-denatured state of apomyoglobin. Biochemistry 2002 1.35
37 Automated identification of functional dynamic contact networks from X-ray crystallography. Nat Methods 2013 1.35
38 Modeling transient collapsed states of an unfolded protein to provide insights into early folding events. Proc Natl Acad Sci U S A 2008 1.33
39 Model-free analysis of protein dynamics: assessment of accuracy and model selection protocols based on molecular dynamics simulation. J Biomol NMR 2004 1.32
40 Structural basis for subversion of cellular control mechanisms by the adenoviral E1A oncoprotein. Proc Natl Acad Sci U S A 2009 1.31
41 Identification of native and non-native structure in kinetic folding intermediates of apomyoglobin. J Mol Biol 2005 1.31
42 Comparison of protein solution structures refined by molecular dynamics simulation in vacuum, with a generalized Born model, and with explicit water. J Biomol NMR 2002 1.28
43 Integrated description of protein dynamics from room-temperature X-ray crystallography and NMR. Proc Natl Acad Sci U S A 2014 1.25
44 Monomeric complex of human orphan estrogen related receptor-2 with DNA: a pseudo-dimer interface mediates extended half-site recognition. J Mol Biol 2003 1.24
45 Structural basis for recruitment of CBP/p300 coactivators by STAT1 and STAT2 transactivation domains. EMBO J 2009 1.23
46 The apomyoglobin folding pathway revisited: structural heterogeneity in the kinetic burst phase intermediate. J Mol Biol 2002 1.23
47 Quantitative analysis of multisite protein-ligand interactions by NMR: binding of intrinsically disordered p53 transactivation subdomains with the TAZ2 domain of CBP. J Am Chem Soc 2012 1.22
48 Structure of the p53 transactivation domain in complex with the nuclear receptor coactivator binding domain of CREB binding protein. Biochemistry 2010 1.21
49 Packing, specificity, and mutability at the binding interface between the p160 coactivator and CREB-binding protein. Protein Sci 2004 1.20
50 Diagnostic chemical shift markers for loop conformation and substrate and cofactor binding in dihydrofolate reductase complexes. Protein Sci 2003 1.20
51 Conformational relaxation following hydride transfer plays a limiting role in dihydrofolate reductase catalysis. Biochemistry 2008 1.19
52 Molecular basis for recognition of methylated and specific DNA sequences by the zinc finger protein Kaiso. Proc Natl Acad Sci U S A 2012 1.18
53 Enhanced picture of protein-folding intermediates using organic solvents in H/D exchange and quench-flow experiments. Proc Natl Acad Sci U S A 2005 1.18
54 Hierarchical folding mechanism of apomyoglobin revealed by ultra-fast H/D exchange coupled with 2D NMR. Proc Natl Acad Sci U S A 2008 1.17
55 CBP/p300 TAZ1 domain forms a structured scaffold for ligand binding. Biochemistry 2005 1.16
56 Measurement of protein unfolding/refolding kinetics and structural characterization of hidden intermediates by NMR relaxation dispersion. Proc Natl Acad Sci U S A 2011 1.15
57 pE-DB: a database of structural ensembles of intrinsically disordered and of unfolded proteins. Nucleic Acids Res 2013 1.13
58 NMR relaxation study of the complex formed between CBP and the activation domain of the nuclear hormone receptor coactivator ACTR. Biochemistry 2008 1.12
59 Divergent evolution of protein conformational dynamics in dihydrofolate reductase. Nat Struct Mol Biol 2013 1.11
60 Elucidation of the protein folding landscape by NMR. Methods Enzymol 2005 1.10
61 The CBP/p300 TAZ1 domain in its native state is not a binding partner of MDM2. Biochem J 2004 1.10
62 Induced fit and "lock and key" recognition of 5S RNA by zinc fingers of transcription factor IIIA. J Mol Biol 2005 1.10
63 Fast and accurate fitting of relaxation dispersion data using the flexible software package GLOVE. J Biomol NMR 2013 1.09
64 ZZ domain of CBP: an unusual zinc finger fold in a protein interaction module. J Mol Biol 2004 1.09
65 Analysis of the RelA:CBP/p300 interaction reveals its involvement in NF-κB-driven transcription. PLoS Biol 2013 1.08
66 Sequence determinants of a protein folding pathway. J Mol Biol 2005 1.08
67 Tailoring relaxation dispersion experiments for fast-associating protein complexes. J Am Chem Soc 2007 1.06
68 Overexpression of post-translationally modified peptides in Escherichia coli by co-expression with modifying enzymes. Protein Expr Purif 2007 1.04
69 Role of a solvent-exposed tryptophan in the recognition and binding of antibiotic substrates for a metallo-beta-lactamase. Protein Sci 2003 1.01
70 Localization of sites of interaction between p23 and Hsp90 in solution. J Biol Chem 2006 1.01
71 Role of the B helix in early folding events in apomyoglobin: evidence from site-directed mutagenesis for native-like long range interactions. J Mol Biol 2003 1.00
72 High pressure NMR reveals that apomyoglobin is an equilibrium mixture from the native to the unfolded. J Mol Biol 2002 1.00
73 The LEF-1 high-mobility group domain undergoes a disorder-to-order transition upon formation of a complex with cognate DNA. Biochemistry 2004 0.99
74 Solution structure of the N-terminal zinc fingers of the Xenopus laevis double-stranded RNA-binding protein ZFa. J Mol Biol 2005 0.97
75 Prion proteins with pathogenic and protective mutations show similar structure and dynamics. Biochemistry 2009 0.97
76 Leu628 of the KIX domain of CBP is a key residue for the interaction with the MLL transactivation domain. FEBS Lett 2010 0.95
77 Prediction of the rotational tumbling time for proteins with disordered segments. J Am Chem Soc 2009 0.94
78 The intrinsically disordered RNR inhibitor Sml1 is a dynamic dimer. Biochemistry 2008 0.93
79 Inhibition of DNA binding by human estrogen-related receptor 2 and estrogen receptor alpha with minor groove binding polyamides. Biochemistry 2005 0.91
80 Mechanisms of transthyretin inhibition of β-amyloid aggregation in vitro. J Neurosci 2013 0.91
81 Structural characterization of partially folded intermediates of apomyoglobin H64F. Protein Sci 2008 0.89
82 Kaiso uses all three zinc fingers and adjacent sequence motifs for high affinity binding to sequence-specific and methyl-CpG DNA targets. FEBS Lett 2012 0.89
83 Localized structural fluctuations promote amyloidogenic conformations in transthyretin. J Mol Biol 2013 0.88
84 The kinetic and equilibrium molten globule intermediates of apoleghemoglobin differ in structure. J Mol Biol 2008 0.88
85 Embryonic neural inducing factor churchill is not a DNA-binding zinc finger protein: solution structure reveals a solvent-exposed beta-sheet and zinc binuclear cluster. J Mol Biol 2007 0.87
86 Identification of endogenous ligands bound to bacterially expressed human and E. coli dihydrofolate reductase by 2D NMR. FEBS Lett 2011 0.87
87 Duration of virus shedding after trivalent intranasal live attenuated influenza vaccination in adults. Infect Control Hosp Epidemiol 2005 0.87
88 Structure of the nuclear factor ALY: insights into post-transcriptional regulatory and mRNA nuclear export processes. Biochemistry 2003 0.85
89 Energetic frustration of apomyoglobin folding: role of the B helix. J Mol Biol 2010 0.83
90 According to current textbooks, a well-defined three-dimensional structure is a prerequisite for the function of a protein. Is this correct? IUBMB Life 2006 0.83
91 Side-chain conformational heterogeneity of intermediates in the Escherichia coli dihydrofolate reductase catalytic cycle. Biochemistry 2013 0.83
92 Folding of a beta-sheet protein monitored by real-time NMR spectroscopy. J Mol Biol 2003 0.81
93 The CH2 domain of CBP/p300 is a novel zinc finger. FEBS Lett 2013 0.80
94 Changes in structure and dynamics of the Fv fragment of a catalytic antibody upon binding of inhibitor. Protein Sci 2003 0.80
95 Consequences of stabilizing the natively disordered f helix for the folding pathway of apomyoglobin. J Mol Biol 2011 0.80
96 NMR solution structure of the peptide fragment 1-30, derived from unprocessed mouse Doppel protein, in DHPC micelles. Biochemistry 2006 0.80
97 Structural characterization of interactions between the double-stranded RNA-binding zinc finger protein JAZ and nucleic acids. Biochemistry 2014 0.79
98 Assignment of a 15 kDa protein complex formed between the p160 coactivator ACTR and CREB binding protein. J Biomol NMR 2002 0.77
99 Probing the non-native H helix translocation in apomyoglobin folding intermediates. Biochemistry 2014 0.76
100 Side chain conformational averaging in human dihydrofolate reductase. Biochemistry 2014 0.75
101 Solid-State NMR Studies Reveal Native-like β-Sheet Structures in Transthyretin Amyloid. Biochemistry 2016 0.75
102 50th anniversary of the Journal of Molecular Biology. J Mol Biol 2009 0.75