Published in J Cell Physiol on December 01, 2002
Endocytosis of epithelial apical junctional proteins by a clathrin-mediated pathway into a unique storage compartment. Mol Biol Cell (2003) 2.76
Caveolin-1-dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo. J Cell Biol (2010) 2.47
Cytokine regulation of tight junctions. Biochim Biophys Acta (2008) 2.16
Role for actin filament turnover and a myosin II motor in cytoskeleton-driven disassembly of the epithelial apical junctional complex. Mol Biol Cell (2004) 2.05
TNF-α signals through PKCζ/NF-κB to alter the tight junction complex and increase retinal endothelial cell permeability. Diabetes (2010) 1.60
The interaction of JRAB/MICAL-L2 with Rab8 and Rab13 coordinates the assembly of tight junctions and adherens junctions. Mol Biol Cell (2007) 1.49
Tyrosine phosphorylated Par3 regulates epithelial tight junction assembly promoted by EGFR signaling. EMBO J (2006) 1.22
JRAB/MICAL-L2 is a junctional Rab13-binding protein mediating the endocytic recycling of occludin. Mol Biol Cell (2006) 1.20
Monocyte chemoattractant protein-1 and the blood-brain barrier. Cell Mol Life Sci (2013) 1.02
Occludin independently regulates permeability under hydrostatic pressure and cell division in retinal pigment epithelial cells. Invest Ophthalmol Vis Sci (2008) 0.97
A detailed method for preparation of a functional and flexible blood-brain barrier model using porcine brain endothelial cells. Brain Res (2013) 0.93
Density-enhanced phosphatase 1 regulates phosphorylation of tight junction proteins and enhances barrier function of epithelial cells. J Biol Chem (2009) 0.90
Abnormal function of platelets and role of angelica sinensis in patients with ulcerative colitis. World J Gastroenterol (2004) 0.89
Resistin increases monolayer permeability of human coronary artery endothelial cells. PLoS One (2013) 0.87
Endocytosis and recycling of tight junction proteins in inflammation. J Biomed Biotechnol (2010) 0.86
Occludin localizes to centrosomes and modifies mitotic entry. J Biol Chem (2011) 0.84
Analysis of occludin trafficking, demonstrating continuous endocytosis, degradation, recycling and biosynthetic secretory trafficking. PLoS One (2014) 0.78
Reactive Oxygen Species/Hypoxia-Inducible Factor-1α/Platelet-Derived Growth Factor-BB Autocrine Loop Contributes to Cocaine-Mediated Alveolar Epithelial Barrier Damage. Am J Respir Cell Mol Biol (2016) 0.75
Platelet-Derived Growth Factor in the Ovarian Follicle Attracts the Stromal Cells of the Fallopian Tube Fimbriae. PLoS One (2016) 0.75
Occludin S490 Phosphorylation Regulates Vascular Endothelial Growth Factor-Induced Retinal Neovascularization. Am J Pathol (2016) 0.75
Sorbin and SH3 domain-containing protein 2 (SORBS2) is a component of the acto-myosin ring at the apical junctional complex in epithelial cells. PLoS One (2017) 0.75
Cell autonomous sonic hedgehog signaling contributes to maintenance of retinal endothelial tight junctions. Exp Eye Res (2017) 0.75
Diabetic retinopathy: seeing beyond glucose-induced microvascular disease. Diabetes (2006) 3.31
Diabetic retinopathy: more than meets the eye. Surv Ophthalmol (2002) 2.95
The Ins2Akita mouse as a model of early retinal complications in diabetes. Invest Ophthalmol Vis Sci (2005) 2.83
Regulation of tight junctions and loss of barrier function in pathophysiology. Int J Biochem Cell Biol (2004) 2.54
A diet-induced mouse model for glutaric aciduria type I. Brain (2006) 2.31
Retinal ganglion cells in diabetes. J Physiol (2008) 2.13
VEGF activation of protein kinase C stimulates occludin phosphorylation and contributes to endothelial permeability. Invest Ophthalmol Vis Sci (2006) 1.86
Occludin phosphorylation and ubiquitination regulate tight junction trafficking and vascular endothelial growth factor-induced permeability. J Biol Chem (2009) 1.81
TNF-α signals through PKCζ/NF-κB to alter the tight junction complex and increase retinal endothelial cell permeability. Diabetes (2010) 1.60
Diabetes reduces basal retinal insulin receptor signaling: reversal with systemic and local insulin. Diabetes (2006) 1.58
Loss of cholinergic and dopaminergic amacrine cells in streptozotocin-diabetic rat and Ins2Akita-diabetic mouse retinas. Invest Ophthalmol Vis Sci (2006) 1.47
Glucocorticoid induction of occludin expression and endothelial barrier requires transcription factor p54 NONO. Invest Ophthalmol Vis Sci (2013) 1.46
Mapping the blood vessels with paracellular permeability in the retinas of diabetic rats. Invest Ophthalmol Vis Sci (2003) 1.45
Dendrite remodeling and other abnormalities in the retinal ganglion cells of Ins2 Akita diabetic mice. Invest Ophthalmol Vis Sci (2008) 1.45
Vascular permeability in ocular disease and the role of tight junctions. Angiogenesis (2007) 1.44
Characterization of insulin signaling in rat retina in vivo and ex vivo. Am J Physiol Endocrinol Metab (2003) 1.29
Whole genome assessment of the retinal response to diabetes reveals a progressive neurovascular inflammatory response. BMC Med Genomics (2008) 1.23
Diabetes downregulates presynaptic proteins and reduces basal synapsin I phosphorylation in rat retina. Eur J Neurosci (2008) 1.20
The blood-retinal barrier: structure and functional significance. Methods Mol Biol (2011) 1.20
Glucocorticoid regulation of endothelial cell tight junction gene expression: novel treatments for diabetic retinopathy. Curr Eye Res (2005) 1.15
Protein kinase cβ phosphorylates occludin regulating tight junction trafficking in vascular endothelial growth factor-induced permeability in vivo. Diabetes (2012) 1.13
Alterations to the blood-retinal barrier in diabetes: cytokines and reactive oxygen species. Antioxid Redox Signal (2011) 1.11
Minocycline prevents retinal inflammation and vascular permeability following ischemia-reperfusion injury. J Neuroinflammation (2013) 1.08
An integrated approach to diabetic retinopathy research. Arch Ophthalmol (2011) 1.07
Ocular Anti-VEGF therapy for diabetic retinopathy: the role of VEGF in the pathogenesis of diabetic retinopathy. Diabetes Care (2014) 1.07
Evaluation of the role of P-glycoprotein in the uptake of paroxetine, clozapine, phenytoin and carbamazapine by bovine retinal endothelial cells. Neuropharmacology (2005) 1.07
NRF2 plays a protective role in diabetic retinopathy in mice. Diabetologia (2013) 1.06
Identification and analysis of occludin phosphosites: a combined mass spectrometry and bioinformatics approach. J Proteome Res (2009) 1.05
Efficacy of interleukin-13 receptor-targeted liposomal doxorubicin in the intracranial brain tumor model. Mol Cancer Ther (2009) 1.04
Effects of ischemic preconditioning and bevacizumab on apoptosis and vascular permeability following retinal ischemia-reperfusion injury. Invest Ophthalmol Vis Sci (2010) 1.02
A transmural pressure gradient induces mechanical and biological adaptive responses in endothelial cells. Am J Physiol Heart Circ Physiol (2003) 1.01
Visual dysfunction associated with diabetic retinopathy. Curr Diab Rep (2010) 1.01
Insulin promotes rat retinal neuronal cell survival in a p70S6K-dependent manner. J Biol Chem (2003) 1.00
Novel atypical PKC inhibitors prevent vascular endothelial growth factor-induced blood-retinal barrier dysfunction. Biochem J (2012) 1.00
Pharmacologic manipulation of sphingosine kinase in retinal endothelial cells: implications for angiogenic ocular diseases. Invest Ophthalmol Vis Sci (2006) 0.99
Occludin is a direct target of thyroid transcription factor-1 (TTF-1/NKX2-1). J Biol Chem (2012) 0.99
Glucocorticoids induce transactivation of tight junction genes occludin and claudin-5 in retinal endothelial cells via a novel cis-element. Exp Eye Res (2008) 0.98
Occludin independently regulates permeability under hydrostatic pressure and cell division in retinal pigment epithelial cells. Invest Ophthalmol Vis Sci (2008) 0.97
Novel potential mechanisms for diabetic macular edema: leveraging new investigational approaches. Curr Diab Rep (2008) 0.96
Differential roles of hyperglycemia and hypoinsulinemia in diabetes induced retinal cell death: evidence for retinal insulin resistance. PLoS One (2011) 0.94
Using the past to inform the future: anti-VEGF therapy as a road map to develop novel therapies for diabetic retinopathy. Diabetes (2013) 0.94
Alterations in expression of angiopoietins and the Tie-2 receptor in the retina of streptozotocin induced diabetic rats. Mol Vis (2004) 0.94
Ablation of 4E-BP1/2 prevents hyperglycemia-mediated induction of VEGF expression in the rodent retina and in Muller cells in culture. Diabetes (2010) 0.93
The occludin and ZO-1 complex, defined by small angle X-ray scattering and NMR, has implications for modulating tight junction permeability. Proc Natl Acad Sci U S A (2012) 0.93
A prize catch for diabetic retinopathy. Nat Med (2007) 0.92
Elevated glucose changes the expression of ionotropic glutamate receptor subunits and impairs calcium homeostasis in retinal neural cells. Invest Ophthalmol Vis Sci (2006) 0.91
Histamine receptors in mammalian retinas. J Comp Neurol (2006) 0.88
Shear stress regulates HUVEC hydraulic conductivity by occludin phosphorylation. Ann Biomed Eng (2005) 0.86
TRPC3 activation by erythropoietin is modulated by TRPC6. J Biol Chem (2008) 0.85
Effect of IL-1beta on survival and energy metabolism of R28 and RGC-5 retinal neurons. Invest Ophthalmol Vis Sci (2008) 0.85
Occludin localizes to centrosomes and modifies mitotic entry. J Biol Chem (2011) 0.84
VEGF increases paracellular transport without altering the solvent-drag reflection coefficient. Microvasc Res (2004) 0.84
Polychromatic angiography for the assessment of VEGF-induced BRB dysfunction in the rabbit retina. Invest Ophthalmol Vis Sci (2013) 0.80
Mechanism of metabolic stroke and spontaneous cerebral hemorrhage in glutaric aciduria type I. Acta Neuropathol Commun (2014) 0.80
Phosphorylation site mapping of endogenous proteins: a combined MS and bioinformatics approach. J Proteome Res (2009) 0.79
Post-translational processing of synaptophysin in the rat retina is disrupted by diabetes. PLoS One (2012) 0.78
A three-pore model describes transport properties of bovine retinal endothelial cells in normal and elevated glucose. Invest Ophthalmol Vis Sci (2011) 0.78
A role for systemic inflammation in diabetic retinopathy. Invest Ophthalmol Vis Sci (2013) 0.77
Ruboxistaurin for diabetic retinopathy. Ophthalmology (2006) 0.75
New insights for glutaric aciduria type I. Brain (2006) 0.75
Synthesis and structure-activity relationships of 2-amino-3-carboxy-4-phenylthiophenes as novel atypical protein kinase C inhibitors. Bioorg Med Chem Lett (2013) 0.75