Published in Angiogenesis on March 06, 2007
Endogenous VEGF is required for visual function: evidence for a survival role on müller cells and photoreceptors. PLoS One (2008) 3.46
Inflammation in diabetic retinopathy. Prog Retin Eye Res (2011) 3.29
The retinal pigment epithelium: something more than a constituent of the blood-retinal barrier--implications for the pathogenesis of diabetic retinopathy. J Biomed Biotechnol (2010) 1.52
Antioxidant or neurotrophic factor treatment preserves function in a mouse model of neovascularization-associated oxidative stress. J Clin Invest (2009) 1.51
A novel transgenic zebrafish model for blood-brain and blood-retinal barrier development. BMC Dev Biol (2010) 1.44
Conditional Müllercell ablation causes independent neuronal and vascular pathologies in a novel transgenic model. J Neurosci (2012) 1.35
Intravenous transferrin, RGD peptide and dual-targeted nanoparticles enhance anti-VEGF intraceptor gene delivery to laser-induced CNV. Gene Ther (2009) 1.34
Mechanisms of leukocyte migration across the blood-retina barrier. Semin Immunopathol (2008) 1.09
An integrated approach to diabetic retinopathy research. Arch Ophthalmol (2011) 1.07
Dietary hyperglycemia, glycemic index and metabolic retinal diseases. Prog Retin Eye Res (2010) 1.06
Identification and analysis of occludin phosphosites: a combined mass spectrometry and bioinformatics approach. J Proteome Res (2009) 1.05
PEDF regulates vascular permeability by a γ-secretase-mediated pathway. PLoS One (2011) 1.05
Placenta growth factor-1 exerts time-dependent stabilization of adherens junctions following VEGF-induced vascular permeability. PLoS One (2011) 1.00
Free insulin-like growth factor binding protein-3 (IGFBP-3) reduces retinal vascular permeability in association with a reduction of acid sphingomyelinase (ASMase). Invest Ophthalmol Vis Sci (2011) 1.00
Glucocorticoids induce transactivation of tight junction genes occludin and claudin-5 in retinal endothelial cells via a novel cis-element. Exp Eye Res (2008) 0.98
Alterations of retinal vasculature in cystathionine-Beta-synthase mutant mice, a model of hyperhomocysteinemia. Invest Ophthalmol Vis Sci (2013) 0.97
Efficient downregulation of VEGF in retinal pigment epithelial cells by integrin ligand-labeled liposome-mediated siRNA delivery. Int J Nanomedicine (2013) 0.91
Ischemia-reperfusion injury induces occludin phosphorylation/ubiquitination and retinal vascular permeability in a VEGFR-2-dependent manner. J Cereb Blood Flow Metab (2014) 0.90
Transcriptome analysis of the Octopus vulgaris central nervous system. PLoS One (2012) 0.86
Alterations of retinal vasculature in cystathionine-β-synthase heterozygous mice: a model of mild to moderate hyperhomocysteinemia. Am J Pathol (2014) 0.86
Inhibition of EGF signaling protects the diabetic retina from insulin-induced vascular leakage. Am J Pathol (2013) 0.86
Potential of the bioflavonoids in the prevention/treatment of ocular disorders. J Pharm Pharmacol (2010) 0.86
Dendrobium chrysotoxum Lindl. alleviates diabetic retinopathy by preventing retinal inflammation and tight junction protein decrease. J Diabetes Res (2015) 0.82
The multifactorial nature of retinal vascular disease. Ophthalmologica (2010) 0.82
Rk1, a ginsenoside, is a new blocker of vascular leakage acting through actin structure remodeling. PLoS One (2013) 0.81
Dexamethasone intravitreal implant in previously treated patients with diabetic macular edema: subgroup analysis of the MEAD study. BMC Ophthalmol (2015) 0.81
Specific role of lymphatic marker podoplanin in retinal pigment epithelial cells. Lymphology (2010) 0.78
MicroRNA-126 contributes to Niaspan treatment induced vascular restoration after diabetic retinopathy. Sci Rep (2016) 0.78
Mechanism of blood-retinal barrier breakdown induced by HIV-1 (Review). Exp Ther Med (2014) 0.77
Intravenously administered anti-recoverin antibody alone does not pass through the blood-retinal barrier. Korean J Ophthalmol (2011) 0.77
Compound 49b Regulates ZO-1 and Occludin Levels in Human Retinal Endothelial Cells and in Mouse Retinal Vasculature. Invest Ophthalmol Vis Sci (2017) 0.77
Deletion of hemojuvelin, an iron-regulatory protein, in mice results in abnormal angiogenesis and vasculogenesis in retina along with reactive gliosis. Invest Ophthalmol Vis Sci (2014) 0.77
IQGAP1 controls tight junction formation through differential regulation of claudin recruitment. J Cell Sci (2015) 0.76
Nanoengineering of therapeutics for retinal vascular disease. Eur J Pharm Biopharm (2015) 0.75
Histone Deacetylase Inhibition Restores Retinal Pigment Epithelium Function in Hyperglycemia. PLoS One (2016) 0.75
Progressive Early Breakdown of Retinal Pigment Epithelium Function in Hyperglycemic Rats. Invest Ophthalmol Vis Sci (2016) 0.75
MarvelD3 regulates the c-Jun N-terminal kinase pathway during eye development in Xenopus. Biol Open (2016) 0.75
Hyperhomocysteinemia Alters Retinal Endothelial Cells Barrier Function and Angiogenic Potential via Activation of Oxidative Stress. Sci Rep (2017) 0.75
A multicenter, 12-month randomized study comparing dexamethasone intravitreal implant with ranibizumab in patients with diabetic macular edema. Graefes Arch Clin Exp Ophthalmol (2016) 0.75
Diabetic retinopathy: more than meets the eye. Surv Ophthalmol (2002) 2.95
The Ins2Akita mouse as a model of early retinal complications in diabetes. Invest Ophthalmol Vis Sci (2005) 2.83
Regulation of tight junctions and loss of barrier function in pathophysiology. Int J Biochem Cell Biol (2004) 2.54
A diet-induced mouse model for glutaric aciduria type I. Brain (2006) 2.31
VEGF activation of protein kinase C stimulates occludin phosphorylation and contributes to endothelial permeability. Invest Ophthalmol Vis Sci (2006) 1.86
Occludin phosphorylation and ubiquitination regulate tight junction trafficking and vascular endothelial growth factor-induced permeability. J Biol Chem (2009) 1.81
TNF-α signals through PKCζ/NF-κB to alter the tight junction complex and increase retinal endothelial cell permeability. Diabetes (2010) 1.60
Diabetes reduces basal retinal insulin receptor signaling: reversal with systemic and local insulin. Diabetes (2006) 1.58
Glucocorticoid induction of occludin expression and endothelial barrier requires transcription factor p54 NONO. Invest Ophthalmol Vis Sci (2013) 1.46
Mapping the blood vessels with paracellular permeability in the retinas of diabetic rats. Invest Ophthalmol Vis Sci (2003) 1.45
Characterization of insulin signaling in rat retina in vivo and ex vivo. Am J Physiol Endocrinol Metab (2003) 1.29
Whole genome assessment of the retinal response to diabetes reveals a progressive neurovascular inflammatory response. BMC Med Genomics (2008) 1.23
The blood-retinal barrier: structure and functional significance. Methods Mol Biol (2011) 1.20
Platelet-derived growth factor mediates tight junction redistribution and increases permeability in MDCK cells. J Cell Physiol (2002) 1.16
Glucocorticoid regulation of endothelial cell tight junction gene expression: novel treatments for diabetic retinopathy. Curr Eye Res (2005) 1.15
Protein kinase cβ phosphorylates occludin regulating tight junction trafficking in vascular endothelial growth factor-induced permeability in vivo. Diabetes (2012) 1.13
Alterations to the blood-retinal barrier in diabetes: cytokines and reactive oxygen species. Antioxid Redox Signal (2011) 1.11
Minocycline prevents retinal inflammation and vascular permeability following ischemia-reperfusion injury. J Neuroinflammation (2013) 1.08
Ocular Anti-VEGF therapy for diabetic retinopathy: the role of VEGF in the pathogenesis of diabetic retinopathy. Diabetes Care (2014) 1.07
Evaluation of the role of P-glycoprotein in the uptake of paroxetine, clozapine, phenytoin and carbamazapine by bovine retinal endothelial cells. Neuropharmacology (2005) 1.07
Identification and analysis of occludin phosphosites: a combined mass spectrometry and bioinformatics approach. J Proteome Res (2009) 1.05
Efficacy of interleukin-13 receptor-targeted liposomal doxorubicin in the intracranial brain tumor model. Mol Cancer Ther (2009) 1.04
Effects of ischemic preconditioning and bevacizumab on apoptosis and vascular permeability following retinal ischemia-reperfusion injury. Invest Ophthalmol Vis Sci (2010) 1.02
A transmural pressure gradient induces mechanical and biological adaptive responses in endothelial cells. Am J Physiol Heart Circ Physiol (2003) 1.01
Insulin promotes rat retinal neuronal cell survival in a p70S6K-dependent manner. J Biol Chem (2003) 1.00
Novel atypical PKC inhibitors prevent vascular endothelial growth factor-induced blood-retinal barrier dysfunction. Biochem J (2012) 1.00
Pharmacologic manipulation of sphingosine kinase in retinal endothelial cells: implications for angiogenic ocular diseases. Invest Ophthalmol Vis Sci (2006) 0.99
Occludin is a direct target of thyroid transcription factor-1 (TTF-1/NKX2-1). J Biol Chem (2012) 0.99
Glucocorticoids induce transactivation of tight junction genes occludin and claudin-5 in retinal endothelial cells via a novel cis-element. Exp Eye Res (2008) 0.98
Occludin independently regulates permeability under hydrostatic pressure and cell division in retinal pigment epithelial cells. Invest Ophthalmol Vis Sci (2008) 0.97
Novel potential mechanisms for diabetic macular edema: leveraging new investigational approaches. Curr Diab Rep (2008) 0.96
Using the past to inform the future: anti-VEGF therapy as a road map to develop novel therapies for diabetic retinopathy. Diabetes (2013) 0.94
Alterations in expression of angiopoietins and the Tie-2 receptor in the retina of streptozotocin induced diabetic rats. Mol Vis (2004) 0.94
The occludin and ZO-1 complex, defined by small angle X-ray scattering and NMR, has implications for modulating tight junction permeability. Proc Natl Acad Sci U S A (2012) 0.93
Ablation of 4E-BP1/2 prevents hyperglycemia-mediated induction of VEGF expression in the rodent retina and in Muller cells in culture. Diabetes (2010) 0.93
Enhanced depth imaging optical coherence tomography of choroidal metastasis. Retina (2014) 0.92
A prize catch for diabetic retinopathy. Nat Med (2007) 0.92
Shear stress regulates HUVEC hydraulic conductivity by occludin phosphorylation. Ann Biomed Eng (2005) 0.86
Occludin localizes to centrosomes and modifies mitotic entry. J Biol Chem (2011) 0.84
VEGF increases paracellular transport without altering the solvent-drag reflection coefficient. Microvasc Res (2004) 0.84
Polychromatic angiography for the assessment of VEGF-induced BRB dysfunction in the rabbit retina. Invest Ophthalmol Vis Sci (2013) 0.80
Mechanism of metabolic stroke and spontaneous cerebral hemorrhage in glutaric aciduria type I. Acta Neuropathol Commun (2014) 0.80
Phosphorylation site mapping of endogenous proteins: a combined MS and bioinformatics approach. J Proteome Res (2009) 0.79
A three-pore model describes transport properties of bovine retinal endothelial cells in normal and elevated glucose. Invest Ophthalmol Vis Sci (2011) 0.78
A role for systemic inflammation in diabetic retinopathy. Invest Ophthalmol Vis Sci (2013) 0.77
Ruboxistaurin for diabetic retinopathy. Ophthalmology (2006) 0.75
Synthesis and structure-activity relationships of 2-amino-3-carboxy-4-phenylthiophenes as novel atypical protein kinase C inhibitors. Bioorg Med Chem Lett (2013) 0.75
New insights for glutaric aciduria type I. Brain (2006) 0.75