Published in Am J Physiol Heart Circ Physiol on October 02, 2003
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The endothelial glycocalyx mediates shear-induced changes in hydraulic conductivity. Am J Physiol Heart Circ Physiol (2009) 1.09
Occludin independently regulates permeability under hydrostatic pressure and cell division in retinal pigment epithelial cells. Invest Ophthalmol Vis Sci (2008) 0.97
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Heparan sulfate proteoglycan is a mechanosensor on endothelial cells. Circ Res (2003) 2.49
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TNF-α signals through PKCζ/NF-κB to alter the tight junction complex and increase retinal endothelial cell permeability. Diabetes (2010) 1.60
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Hydrocortisone decreases retinal endothelial cell water and solute flux coincident with increased content and decreased phosphorylation of occludin. J Neurochem (2002) 1.54
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Glucocorticoid induction of occludin expression and endothelial barrier requires transcription factor p54 NONO. Invest Ophthalmol Vis Sci (2013) 1.46
Mapping the blood vessels with paracellular permeability in the retinas of diabetic rats. Invest Ophthalmol Vis Sci (2003) 1.45
Vascular permeability in ocular disease and the role of tight junctions. Angiogenesis (2007) 1.44
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Characterization of insulin signaling in rat retina in vivo and ex vivo. Am J Physiol Endocrinol Metab (2003) 1.29
Whole genome assessment of the retinal response to diabetes reveals a progressive neurovascular inflammatory response. BMC Med Genomics (2008) 1.23
Asynchronous shear stress and circumferential strain reduces endothelial NO synthase and cyclooxygenase-2 but induces endothelin-1 gene expression in endothelial cells. Arterioscler Thromb Vasc Biol (2004) 1.22
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Interstitial flow promotes vascular fibroblast, myofibroblast, and smooth muscle cell motility in 3-D collagen I via upregulation of MMP-1. Am J Physiol Heart Circ Physiol (2009) 1.18
Functions of insulin and insulin receptor signaling in retina: possible implications for diabetic retinopathy. Prog Retin Eye Res (2003) 1.18
In vitro study of LDL transport under pressurized (convective) conditions. Am J Physiol Heart Circ Physiol (2007) 1.18
Correlation of in vivo clot deposition with the flow characteristics in the 50 cc penn state artificial heart: a preliminary study. ASAIO J (2005) 1.18
Regurgitant flow field characteristics of the St. Jude bileaflet mechanical heart valve under physiologic pulsatile flow using particle image velocimetry. Artif Organs (2003) 1.17
Platelet-derived growth factor mediates tight junction redistribution and increases permeability in MDCK cells. J Cell Physiol (2002) 1.16
The structural stability of the endothelial glycocalyx after enzymatic removal of glycosaminoglycans. PLoS One (2012) 1.15
Glucocorticoid regulation of endothelial cell tight junction gene expression: novel treatments for diabetic retinopathy. Curr Eye Res (2005) 1.15
Heparan sulfate proteoglycans mediate interstitial flow mechanotransduction regulating MMP-13 expression and cell motility via FAK-ERK in 3D collagen. PLoS One (2011) 1.14
Protein kinase cβ phosphorylates occludin regulating tight junction trafficking in vascular endothelial growth factor-induced permeability in vivo. Diabetes (2012) 1.13
Diabetes alters sphingolipid metabolism in the retina: a potential mechanism of cell death in diabetic retinopathy. Diabetes (2006) 1.13
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Interstitial flow induces MMP-1 expression and vascular SMC migration in collagen I gels via an ERK1/2-dependent and c-Jun-mediated mechanism. Am J Physiol Heart Circ Physiol (2009) 1.11
Shear stress inhibits smooth muscle cell migration via nitric oxide-mediated downregulation of matrix metalloproteinase-2 activity. Am J Physiol Heart Circ Physiol (2005) 1.10
The endothelial glycocalyx mediates shear-induced changes in hydraulic conductivity. Am J Physiol Heart Circ Physiol (2009) 1.09
Minocycline prevents retinal inflammation and vascular permeability following ischemia-reperfusion injury. J Neuroinflammation (2013) 1.08
Ocular Anti-VEGF therapy for diabetic retinopathy: the role of VEGF in the pathogenesis of diabetic retinopathy. Diabetes Care (2014) 1.07
Nonobese, insulin-deficient Ins2Akita mice develop type 2 diabetes phenotypes including insulin resistance and cardiac remodeling. Am J Physiol Endocrinol Metab (2007) 1.07
Evaluation of the role of P-glycoprotein in the uptake of paroxetine, clozapine, phenytoin and carbamazapine by bovine retinal endothelial cells. Neuropharmacology (2005) 1.07
Inner retinal visual dysfunction is a sensitive marker of non-proliferative diabetic retinopathy. Br J Ophthalmol (2011) 1.06
Shear stress modulation of smooth muscle cell marker genes in 2-D and 3-D depends on mechanotransduction by heparan sulfate proteoglycans and ERK1/2. PLoS One (2010) 1.06
IGF-I prevents glutamate-mediated bax translocation and cytochrome C release in O4+ oligodendrocyte progenitors. Glia (2004) 1.06
Identification and analysis of occludin phosphosites: a combined mass spectrometry and bioinformatics approach. J Proteome Res (2009) 1.05
Efficacy of interleukin-13 receptor-targeted liposomal doxorubicin in the intracranial brain tumor model. Mol Cancer Ther (2009) 1.04
The retinal proteome in experimental diabetic retinopathy: up-regulation of crystallins and reversal by systemic and periocular insulin. Mol Cell Proteomics (2008) 1.04
Neurodegeneration in the pathogenesis of diabetic retinopathy: molecular mechanisms and therapeutic implications. Curr Med Chem (2013) 1.03
The role of apoptosis in LDL transport through cultured endothelial cell monolayers. Atherosclerosis (2009) 1.03
Sphingosine-1-phosphate protects endothelial glycocalyx by inhibiting syndecan-1 shedding. Am J Physiol Heart Circ Physiol (2013) 1.03
Effects of ischemic preconditioning and bevacizumab on apoptosis and vascular permeability following retinal ischemia-reperfusion injury. Invest Ophthalmol Vis Sci (2010) 1.02
Regulation of capillary hydraulic conductivity in response to an acute change in shear. Am J Physiol Heart Circ Physiol (2005) 1.01
Effects of fluid shear stress on adventitial fibroblast migration: implications for flow-mediated mechanisms of arterialization and intimal hyperplasia. Am J Physiol Heart Circ Physiol (2007) 1.01
Wall shear-rate estimation within the 50cc Penn State artificial heart using particle image velocimetry. J Biomech Eng (2004) 1.01
Fluid shear stress regulates the invasive potential of glioma cells via modulation of migratory activity and matrix metalloproteinase expression. PLoS One (2011) 1.01
Mechano-sensing and transduction by endothelial surface glycocalyx: composition, structure, and function. Wiley Interdiscip Rev Syst Biol Med (2013) 1.01
Diabetic retinopathy: loss of neuroretinal adaptation to the diabetic metabolic environment. Ann N Y Acad Sci (2014) 1.01
Insulin promotes rat retinal neuronal cell survival in a p70S6K-dependent manner. J Biol Chem (2003) 1.00
Novel atypical PKC inhibitors prevent vascular endothelial growth factor-induced blood-retinal barrier dysfunction. Biochem J (2012) 1.00
Vascular smooth muscle cell glycocalyx influences shear stress-mediated contractile response. J Appl Physiol (1985) (2004) 1.00
Pharmacologic manipulation of sphingosine kinase in retinal endothelial cells: implications for angiogenic ocular diseases. Invest Ophthalmol Vis Sci (2006) 0.99
Occludin is a direct target of thyroid transcription factor-1 (TTF-1/NKX2-1). J Biol Chem (2012) 0.99
Analysis of glucose metabolism in diabetic rat retinas. Am J Physiol Endocrinol Metab (2005) 0.99
Glucocorticoids induce transactivation of tight junction genes occludin and claudin-5 in retinal endothelial cells via a novel cis-element. Exp Eye Res (2008) 0.98
Occludin independently regulates permeability under hydrostatic pressure and cell division in retinal pigment epithelial cells. Invest Ophthalmol Vis Sci (2008) 0.97
Fluid dynamic analysis of the 50 cc Penn State artificial heart under physiological operating conditions using particle image velocimetry. J Biomech Eng (2004) 0.97
Quantification of the endothelial surface glycocalyx on rat and mouse blood vessels. Microvasc Res (2012) 0.96
Novel potential mechanisms for diabetic macular edema: leveraging new investigational approaches. Curr Diab Rep (2008) 0.96
Predicting development of proliferative diabetic retinopathy. Diabetes Care (2012) 0.95
Alterations in expression of angiopoietins and the Tie-2 receptor in the retina of streptozotocin induced diabetic rats. Mol Vis (2004) 0.94
Using the past to inform the future: anti-VEGF therapy as a road map to develop novel therapies for diabetic retinopathy. Diabetes (2013) 0.94
Differential roles of hyperglycemia and hypoinsulinemia in diabetes induced retinal cell death: evidence for retinal insulin resistance. PLoS One (2011) 0.94
The occludin and ZO-1 complex, defined by small angle X-ray scattering and NMR, has implications for modulating tight junction permeability. Proc Natl Acad Sci U S A (2012) 0.93
Ablation of 4E-BP1/2 prevents hyperglycemia-mediated induction of VEGF expression in the rodent retina and in Muller cells in culture. Diabetes (2010) 0.93
Fluid shear stress induces the clustering of heparan sulfate via mobility of glypican-1 in lipid rafts. Am J Physiol Heart Circ Physiol (2013) 0.93
Coronary endothelium expresses a pathologic gene pattern compared to aortic endothelium: correlation of asynchronous hemodynamics and pathology in vivo. Atherosclerosis (2006) 0.93
Diaphragm motion affects flow patterns in an artificial heart. Artif Organs (2003) 0.93
The transport of LDL across the deformable arterial wall: the effect of endothelial cell turnover and intimal deformation under hypertension. Am J Physiol Heart Circ Physiol (2009) 0.93
Heparan sulfate proteoglycan mediates shear stress-induced endothelial gene expression in mouse embryonic stem cell-derived endothelial cells. Biotechnol Bioeng (2011) 0.92
A prize catch for diabetic retinopathy. Nat Med (2007) 0.92
The role of mitosis in LDL transport through cultured endothelial cell monolayers. Am J Physiol Heart Circ Physiol (2010) 0.92
Subconjunctivally implantable hydrogels with degradable and thermoresponsive properties for sustained release of insulin to the retina. Biomaterials (2009) 0.91