Published in Nat Struct Mol Biol on March 31, 2013
Long non-coding RNAs: new players in cell differentiation and development. Nat Rev Genet (2013) 5.48
The Xist lncRNA exploits three-dimensional genome architecture to spread across the X chromosome. Science (2013) 4.12
X chromosome regulation: diverse patterns in development, tissues and disease. Nat Rev Genet (2014) 1.36
Three-dimensional super-resolution microscopy of the inactive X chromosome territory reveals a collapse of its active nuclear compartment harboring distinct Xist RNA foci. Epigenetics Chromatin (2014) 1.12
Epigenetic functions of smchd1 repress gene clusters on the inactive X chromosome and on autosomes. Mol Cell Biol (2013) 1.07
Mechanisms of cohesin-mediated gene regulation and lessons learned from cohesinopathies. Biochim Biophys Acta (2013) 0.97
Transcriptional control of a whole chromosome: emerging models for dosage compensation. Nat Struct Mol Biol (2014) 0.95
Biallelic Mutations in MYPN, Encoding Myopalladin, Are Associated with Childhood-Onset, Slowly Progressive Nemaline Myopathy. Am J Hum Genet (2016) 0.91
Variable escape from X-chromosome inactivation: identifying factors that tip the scales towards expression. Bioessays (2014) 0.91
Long non-coding RNAs: spatial amplifiers that control nuclear structure and gene expression. Nat Rev Mol Cell Biol (2016) 0.91
Deletion of DXZ4 on the human inactive X chromosome alters higher-order genome architecture. Proc Natl Acad Sci U S A (2016) 0.90
The Xist RNA-PRC2 complex at 20-nm resolution reveals a low Xist stoichiometry and suggests a hit-and-run mechanism in mouse cells. Proc Natl Acad Sci U S A (2015) 0.87
The Mbd1-Atf7ip-Setdb1 pathway contributes to the maintenance of X chromosome inactivation. Epigenetics Chromatin (2014) 0.87
Genome-wide binding and mechanistic analyses of Smchd1-mediated epigenetic regulation. Proc Natl Acad Sci U S A (2015) 0.84
Genetic and epigenetic characteristics of FSHD-associated 4q and 10q D4Z4 that are distinct from non-4q/10q D4Z4 homologs. Hum Mutat (2014) 0.84
Mechanisms of x chromosome dosage compensation. J Genomics (2015) 0.82
Human X chromosome inactivation and reactivation: implications for cell reprogramming and disease. Philos Trans R Soc Lond B Biol Sci (2017) 0.81
Loss of WSTF results in spontaneous fluctuations of heterochromatin formation and resolution, combined with substantial changes to gene expression. BMC Genomics (2013) 0.81
Double SMCHD1 variants in FSHD2: the synergistic effect of two SMCHD1 variants on D4Z4 hypomethylation and disease penetrance in FSHD2. Eur J Hum Genet (2015) 0.79
Epigenetic characterization of the growth hormone gene identifies SmcHD1 as a regulator of autosomal gene clusters. PLoS One (2014) 0.79
Identification of protein complexes that bind to histone H3 combinatorial modifications using super-SILAC and weighted correlation network analysis. Nucleic Acids Res (2015) 0.78
SMCHD1 accumulates at DNA damage sites and facilitates the repair of DNA double-strand breaks. J Cell Sci (2014) 0.78
Structural maintenance of chromosomes flexible hinge domain containing 1 (SMCHD1) promotes non-homologous end joining and inhibits homologous recombination repair upon DNA damage. J Biol Chem (2014) 0.76
Nuclear architecture and gene silencing in olfactory sensory neurons. Bioarchitecture (2014) 0.76
Increased DUX4 expression during muscle differentiation correlates with decreased SMCHD1 protein levels at D4Z4. Epigenetics (2015) 0.76
Exosomes maintain cellular homeostasis by excreting harmful DNA from cells. Nat Commun (2017) 0.75
lncRHOXF1, a Long Noncoding RNA from the X Chromosome That Suppresses Viral Response Genes during Development of the Early Human Placenta. Mol Cell Biol (2016) 0.75
Allele-specific analysis of cell fusion-mediated pluripotent reprograming reveals distinct and predictive susceptibilities of human X-linked genes to reactivation. Genome Biol (2017) 0.75
Independent Mechanisms Target SMCHD1 to Trimethylated Histone H3 Lysine 9-Modified Chromatin and the Inactive X Chromosome. Mol Cell Biol (2015) 0.75
The dataset of proteins specifically interacted with activated TICAM-1. Data Brief (2016) 0.75
Segregation between SMCHD1 mutation, D4Z4 hypomethylation and Facio-Scapulo-Humeral Dystrophy: a case report. BMC Med Genet (2016) 0.75
The Sequence Alignment/Map format and SAMtools. Bioinformatics (2009) 232.39
Fast and accurate short read alignment with Burrows-Wheeler transform. Bioinformatics (2009) 190.94
Gene action in the X-chromosome of the mouse (Mus musculus L.). Nature (1961) 23.98
The Polycomb complex PRC2 and its mark in life. Nature (2011) 11.97
Partitioning and plasticity of repressive histone methylation states in mammalian chromatin. Mol Cell (2003) 11.33
Role of histone H3 lysine 27 methylation in X inactivation. Science (2003) 9.85
A gene from the region of the human X inactivation centre is expressed exclusively from the inactive X chromosome. Nature (1991) 8.22
The human XIST gene: analysis of a 17 kb inactive X-specific RNA that contains conserved repeats and is highly localized within the nucleus. Cell (1992) 8.05
Establishment of histone h3 methylation on the inactive X chromosome requires transient recruitment of Eed-Enx1 polycomb group complexes. Dev Cell (2003) 7.11
XIST RNA paints the inactive X chromosome at interphase: evidence for a novel RNA involved in nuclear/chromosome structure. J Cell Biol (1996) 5.51
HP1 and the dynamics of heterochromatin maintenance. Nat Rev Mol Cell Biol (2004) 4.38
A shift from reversible to irreversible X inactivation is triggered during ES cell differentiation. Mol Cell (2000) 4.26
Dosage compensation in mammals: fine-tuning the expression of the X chromosome. Genes Dev (2006) 4.17
A morphological distinction between neurones of the male and female, and the behaviour of the nucleolar satellite during accelerated nucleoprotein synthesis. Nature (1949) 3.70
Genome-wide dynamics of replication timing revealed by in vitro models of mouse embryogenesis. Genome Res (2009) 3.36
A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1. Nat Cell Biol (2004) 3.04
Synergism of Xist RNA, DNA methylation, and histone hypoacetylation in maintaining X chromosome inactivation. J Cell Biol (2001) 2.94
Facultative heterochromatin: is there a distinctive molecular signature? Mol Cell (2007) 2.94
The organization of histone H3 modifications as revealed by a panel of specific monoclonal antibodies. Cell Struct Funct (2008) 2.75
A structural-maintenance-of-chromosomes hinge domain-containing protein is required for RNA-directed DNA methylation. Nat Genet (2008) 2.74
Conditional deletion of Xist disrupts histone macroH2A localization but not maintenance of X inactivation. Nat Genet (1999) 2.62
The inactive X chromosome adopts a unique three-dimensional conformation that is dependent on Xist RNA. Genes Dev (2011) 2.53
Formation of the sex chromatin by a single X-chromosome in liver cells of Rattus norvegicus. Exp Cell Res (1959) 2.35
SmcHD1, containing a structural-maintenance-of-chromosomes hinge domain, has a critical role in X inactivation. Nat Genet (2008) 2.19
Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation. Nat Cell Biol (2010) 2.18
CENP-A, -B, and -C chromatin complex that contains the I-type alpha-satellite array constitutes the prekinetochore in HeLa cells. Mol Cell Biol (2002) 2.11
X inactivation and the complexities of silencing a sex chromosome. Curr Opin Cell Biol (2009) 2.09
MORC family ATPases required for heterochromatin condensation and gene silencing. Science (2012) 1.97
Involvement of a GHKL ATPase in RNA-directed DNA methylation in Arabidopsis thaliana. Curr Biol (2012) 1.92
Multiple spatially distinct types of facultative heterochromatin on the human inactive X chromosome. Proc Natl Acad Sci U S A (2004) 1.80
Gracefully ageing at 50, X-chromosome inactivation becomes a paradigm for RNA and chromatin control. Nat Rev Mol Cell Biol (2011) 1.66
Space and time in the nucleus: developmental control of replication timing and chromosome architecture. Cold Spring Harb Symp Quant Biol (2010) 1.57
Tracking epigenetic histone modifications in single cells using Fab-based live endogenous modification labeling. Nucleic Acids Res (2011) 1.49
Smchd1-dependent and -independent pathways determine developmental dynamics of CpG island methylation on the inactive X chromosome. Dev Cell (2012) 1.47
Variation in Xi chromatin organization and correlation of the H3K27me3 chromatin territories to transcribed sequences by microarray analysis. Chromosoma (2006) 1.25
MutL homologs in restriction-modification systems and the origin of eukaryotic MORC ATPases. Biol Direct (2008) 1.23
The facultative heterochromatin of the inactive X chromosome has a distinctive condensed ultrastructure. J Cell Sci (2008) 1.15
Epigenetic modifications on X chromosomes in marsupial and monotreme mammals and implications for evolution of dosage compensation. Proc Natl Acad Sci U S A (2010) 1.10
X-changing information on X inactivation. Exp Cell Res (2010) 1.03
Evolution from XIST-independent to XIST-controlled X-chromosome inactivation: epigenetic modifications in distantly related mammals. PLoS One (2011) 1.01
Nuclear organization and dosage compensation. Cold Spring Harb Perspect Biol (2010) 0.94
A top-down analysis of Xa- and Xi-territories reveals differences of higher order structure at ≥ 20 Mb genomic length scales. Nucleus (2011) 0.89
Spatial distribution of histone isoforms on the bovine active and inactive X chromosomes. Sex Dev (2008) 0.88
Mosaic heterochromatin of the inactive X chromosome in vole Microtus rossiaemeridionalis. Mamm Genome (2009) 0.84
Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting. Nature (2004) 7.42
Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET. Nature (2010) 3.55
Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis. EMBO J (2006) 3.53
Priming of centromere for CENP-A recruitment by human hMis18alpha, hMis18beta, and M18BP1. Dev Cell (2007) 3.25
U1 snRNA associates with TFIIH and regulates transcriptional initiation. Nat Struct Biol (2002) 3.25
Phase II study of SMILE chemotherapy for newly diagnosed stage IV, relapsed, or refractory extranodal natural killer (NK)/T-cell lymphoma, nasal type: the NK-Cell Tumor Study Group study. J Clin Oncol (2011) 3.10
HDAC8 mutations in Cornelia de Lange syndrome affect the cohesin acetylation cycle. Nature (2012) 3.08
G9a/GLP complexes independently mediate H3K9 and DNA methylation to silence transcription. EMBO J (2008) 3.08
Survivin reads phosphorylated histone H3 threonine 3 to activate the mitotic kinase Aurora B. Science (2010) 3.07
Human Blinkin/AF15q14 is required for chromosome alignment and the mitotic checkpoint through direct interaction with Bub1 and BubR1. Dev Cell (2007) 3.06
DNA damage-dependent acetylation and ubiquitination of H2AX enhances chromatin dynamics. Mol Cell Biol (2007) 3.03
Dynamic behavior of Nuf2-Hec1 complex that localizes to the centrosome and centromere and is essential for mitotic progression in vertebrate cells. J Cell Sci (2003) 2.78
The organization of histone H3 modifications as revealed by a panel of specific monoclonal antibodies. Cell Struct Funct (2008) 2.75
alpha-Klotho as a regulator of calcium homeostasis. Science (2007) 2.71
Rapamycin sensitivity of the Schizosaccharomyces pombe tor2 mutant and organization of two highly phosphorylated TOR complexes by specific and common subunits. Genes Cells (2007) 2.53
Helicobacter pylori CagA targets PAR1/MARK kinase to disrupt epithelial cell polarity. Nature (2007) 2.48
Crystal structure of the human centromeric nucleosome containing CENP-A. Nature (2011) 2.42
Cytosolic chaperonin prevents polyglutamine toxicity with altering the aggregation state. Nat Cell Biol (2006) 2.37
Broad chromosomal domains of histone modification patterns in C. elegans. Genome Res (2010) 2.36
Impeding Xist expression from the active X chromosome improves mouse somatic cell nuclear transfer. Science (2010) 2.34
The histone H3K36 methyltransferase MES-4 acts epigenetically to transmit the memory of germline gene expression to progeny. PLoS Genet (2010) 2.30
Manipulation of alternative splicing by a newly developed inhibitor of Clks. J Biol Chem (2004) 2.26
The functional organization of mitochondrial genomes in human cells. BMC Biol (2004) 2.20
A wave of nascent transcription on activated human genes. Proc Natl Acad Sci U S A (2009) 2.18
Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation. Nat Cell Biol (2010) 2.18
Epigenetic engineering shows H3K4me2 is required for HJURP targeting and CENP-A assembly on a synthetic human kinetochore. EMBO J (2010) 2.17
Role for piRNAs and noncoding RNA in de novo DNA methylation of the imprinted mouse Rasgrf1 locus. Science (2011) 2.17
CENP-A, -B, and -C chromatin complex that contains the I-type alpha-satellite array constitutes the prekinetochore in HeLa cells. Mol Cell Biol (2002) 2.11
Plasma viral microRNA profiles reveal potential biomarkers for chronic active Epstein-Barr virus infection. J Infect Dis (2013) 2.11
Comprehensive analysis of the ICEN (Interphase Centromere Complex) components enriched in the CENP-A chromatin of human cells. Genes Cells (2006) 2.03
Report from the Working Group of the Molecular Biology Society of Japan for the investigation of fraud in research papers. Genes Cells (2009) 2.02
Independence of repressive histone marks and chromatin compaction during senescent heterochromatic layer formation. Mol Cell (2012) 2.02
Systemic cytokine responses in patients with influenza-associated encephalopathy. J Infect Dis (2003) 1.98
The augmin complex plays a critical role in spindle microtubule generation for mitotic progression and cytokinesis in human cells. Proc Natl Acad Sci U S A (2009) 1.98
The E3 ligase TTC3 facilitates ubiquitination and degradation of phosphorylated Akt. Dev Cell (2009) 1.96
Activity-dependent synaptogenesis: regulation by a CaM-kinase kinase/CaM-kinase I/betaPIX signaling complex. Neuron (2008) 1.94
MITOPLD is a mitochondrial protein essential for nuage formation and piRNA biogenesis in the mouse germline. Dev Cell (2011) 1.94
Polycomb associates genome-wide with a specific RNA polymerase II variant, and regulates metabolic genes in ESCs. Cell Stem Cell (2012) 1.80
Alterations of lysine modifications on the histone H3 N-tail under drought stress conditions in Arabidopsis thaliana. Plant Cell Physiol (2008) 1.76
A combination of oral sildenafil and beraprost ameliorates pulmonary hypertension in rats. Am J Respir Crit Care Med (2003) 1.74
H3K9 and H3K14 acetylation co-occur at many gene regulatory elements, while H3K14ac marks a subset of inactive inducible promoters in mouse embryonic stem cells. BMC Genomics (2012) 1.73
Active establishment of centromeric CENP-A chromatin by RSF complex. J Cell Biol (2009) 1.69
Proposed guidelines for diagnosing chronic active Epstein-Barr virus infection. Am J Hematol (2005) 1.65
Oxidative stress in obstructive sleep apnea. Chest (2005) 1.65
Nasal continuous positive airway pressure improves quality of life in obesity hypoventilation syndrome. Sleep Breath (2003) 1.59
NEAT1 long noncoding RNA regulates transcription via protein sequestration within subnuclear bodies. Mol Biol Cell (2013) 1.59
Oncogenesis by sequestration of CBP/p300 in transcriptionally inactive hyperacetylated chromatin domains. EMBO J (2010) 1.58
Regulation of axonal extension and growth cone motility by calmodulin-dependent protein kinase I. J Neurosci (2004) 1.57
Effect of serum leptin levels on hypercapnic ventilatory response in obstructive sleep apnea. Respiration (2007) 1.56
Clinical and virological characteristics of 15 patients with chronic active Epstein-Barr virus infection treated with hematopoietic stem cell transplantation. Clin Infect Dis (2008) 1.54
De novo DNA methylation independent establishment of maternal imprint on X chromosome in mouse oocytes. Genesis (2008) 1.51
Crucial role of antisense transcription across the Xist promoter in Tsix-mediated Xist chromatin modification. Development (2007) 1.50
Requirement of chromatid cohesion proteins rad21/scc1 and mis4/scc2 for normal spindle-kinetochore interaction in fission yeast. Curr Biol (2002) 1.50
Tracking epigenetic histone modifications in single cells using Fab-based live endogenous modification labeling. Nucleic Acids Res (2011) 1.49
Trial of intraventricular ribavirin therapy for subacute sclerosing panencephalitis in Japan. Brain Dev (2003) 1.48
Cytoplasmic polyadenylation element binding protein-dependent protein synthesis is regulated by calcium/calmodulin-dependent protein kinase II. J Neurosci (2004) 1.48
Inhibitors of the proteasome suppress homologous DNA recombination in mammalian cells. Cancer Res (2007) 1.48
The constitutive centromere component CENP-50 is required for recovery from spindle damage. Mol Cell Biol (2005) 1.44
The 3rd DBCLS BioHackathon: improving life science data integration with Semantic Web technologies. J Biomed Semantics (2013) 1.44
Breaking the HAC Barrier: histone H3K9 acetyl/methyl balance regulates CENP-A assembly. EMBO J (2012) 1.41
AZD2171 shows potent antitumor activity against gastric cancer over-expressing fibroblast growth factor receptor 2/keratinocyte growth factor receptor. Clin Cancer Res (2007) 1.41
Two cases of endobronchial neurilemmoma and review of the literature in Japan. Intern Med (2003) 1.41
Cocaine-induced CREB phosphorylation in nucleus accumbens of cocaine-sensitized rats is enabled by enhanced activation of extracellular signal-related kinase, but not protein kinase A. J Neurochem (2005) 1.39
The affinity of hemoglobin for oxygen affects ventilatory responses in mutant mice with Presbyterian hemoglobinopathy. Am J Physiol Regul Integr Comp Physiol (2003) 1.39
Oral administration of a novel long-acting prostacyclin agonist with thromboxane synthase inhibitory activity for pulmonary arterial hypertension. Circ J (2013) 1.39
Amphotericin B-induced nephrogenic diabetes insipidus in a case of cryptococcemia. Intern Med (2005) 1.38
The interaction between cap-binding complex and RNA export factor is required for intronless mRNA export. J Biol Chem (2007) 1.38
A proximal conserved repeat in the Xist gene is essential as a genomic element for X-inactivation in mouse. Development (2008) 1.35
A novel histone exchange factor, protein phosphatase 2Cgamma, mediates the exchange and dephosphorylation of H2A-H2B. J Cell Biol (2006) 1.34
Structural basis of instability of the nucleosome containing a testis-specific histone variant, human H3T. Proc Natl Acad Sci U S A (2010) 1.32
Enhanced chromatin dynamics by FACT promotes transcriptional restart after UV-induced DNA damage. Mol Cell (2013) 1.30
Histone chaperone activity of Fanconi anemia proteins, FANCD2 and FANCI, is required for DNA crosslink repair. EMBO J (2012) 1.30
Clamp and clamp loader structures of the human checkpoint protein complexes, Rad9-1-1 and Rad17-RFC. Genes Cells (2002) 1.30
Chromosome engineering allows the efficient isolation of vertebrate neocentromeres. Dev Cell (2013) 1.30
Dicer regulates Xist promoter methylation in ES cells indirectly through transcriptional control of Dnmt3a. Epigenetics Chromatin (2008) 1.30
A novel myc target gene, mina53, that is involved in cell proliferation. J Biol Chem (2002) 1.29
The initial phase of chromosome condensation requires Cdk1-mediated phosphorylation of the CAP-D3 subunit of condensin II. Genes Dev (2011) 1.27
Arabidopsis HDA6 regulates locus-directed heterochromatin silencing in cooperation with MET1. PLoS Genet (2011) 1.27
Visualizing histone modifications in living cells: spatiotemporal dynamics of H3 phosphorylation during interphase. J Cell Biol (2009) 1.26
Loss-of-function HDAC8 mutations cause a phenotypic spectrum of Cornelia de Lange syndrome-like features, ocular hypertelorism, large fontanelle and X-linked inheritance. Hum Mol Genet (2014) 1.25
Vasohibin-1 expression in endothelium of tumor blood vessels regulates angiogenesis. Am J Pathol (2009) 1.24
Calcium activation of ERK mediated by calmodulin kinase I. J Biol Chem (2004) 1.24
Dissection of the essential steps for condensin accumulation at kinetochores and rDNAs during fission yeast mitosis. J Cell Biol (2008) 1.24
Autocatalytic differentiation of epigenetic modifications within the Arabidopsis genome. EMBO J (2010) 1.23
Redistribution of the Lamin B1 genomic binding profile affects rearrangement of heterochromatic domains and SAHF formation during senescence. Genes Dev (2013) 1.23
Trans-generational epigenetic regulation of C. elegans primordial germ cells. Epigenetics Chromatin (2010) 1.22
Transduction of RNA-directed DNA methylation signals to repressive histone marks in Arabidopsis thaliana. EMBO J (2009) 1.21
Inner centromere formation requires hMis14, a trident kinetochore protein that specifically recruits HP1 to human chromosomes. J Cell Biol (2010) 1.21
Herpes simplex virus type 1 UL51 protein is involved in maturation and egress of virus particles. J Virol (2005) 1.19