Published in Eur J Biochem on November 01, 2002
The notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis. Cell (2009) 5.33
Wnt3a plays a major role in the segmentation clock controlling somitogenesis. Dev Cell (2003) 3.15
Notch2, but not Notch1, is required for proximal fate acquisition in the mammalian nephron. Development (2007) 2.70
The Notch ligands DLL1 and JAG2 act synergistically to regulate hair cell development in the mammalian inner ear. Development (2005) 2.36
Argyrin a reveals a critical role for the tumor suppressor protein p27(kip1) in mediating antitumor activities in response to proteasome inhibition. Cancer Cell (2008) 2.12
DLL1-mediated Notch activation regulates endothelial identity in mouse fetal arteries. Blood (2009) 2.07
Proneural bHLH and Brn proteins coregulate a neurogenic program through cooperative binding to a conserved DNA motif. Dev Cell (2006) 2.06
A mutation in hairless dogs implicates FOXI3 in ectodermal development. Science (2008) 2.06
Deletion of Notch1 converts pro-T cells to dendritic cells and promotes thymic B cells by cell-extrinsic and cell-intrinsic mechanisms. Immunity (2008) 2.05
Incoming RNA virus nucleocapsids containing a 5'-triphosphorylated genome activate RIG-I and antiviral signaling. Cell Host Microbe (2013) 1.95
The CHK2-BRCA1 tumour suppressor pathway ensures chromosomal stability in human somatic cells. Nat Cell Biol (2010) 1.81
Premature myogenic differentiation and depletion of progenitor cells cause severe muscle hypotrophy in Delta1 mutants. Proc Natl Acad Sci U S A (2006) 1.76
WNT signaling, in synergy with T/TBX6, controls Notch signaling by regulating Dll1 expression in the presomitic mesoderm of mouse embryos. Genes Dev (2004) 1.74
Expression of Notch pathway components in fetal and adult mouse small intestine. Gene Expr Patterns (2002) 1.72
Genome-wide analysis in German shepherd dogs reveals association of a locus on CFA 27 with atopic dermatitis. PLoS Genet (2013) 1.69
A missense mutation in the SERPINH1 gene in Dachshunds with osteogenesis imperfecta. PLoS Genet (2009) 1.68
Erythropoietin preserves the endothelial differentiation capacity of cardiac progenitor cells and reduces heart failure during anticancer therapies. Cell Stem Cell (2011) 1.67
A high density SNP array for the domestic horse and extant Perissodactyla: utility for association mapping, genetic diversity, and phylogeny studies. PLoS Genet (2012) 1.66
Ascl1 and Gsh1/2 control inhibitory and excitatory cell fate in spinal sensory interneurons. Nat Neurosci (2006) 1.61
Live imaging and genetic analysis of mouse notochord formation reveals regional morphogenetic mechanisms. Dev Cell (2007) 1.59
Requirement for galectin-3 in apical protein sorting. Curr Biol (2006) 1.55
Notch ligand Delta-like 1 is essential for postnatal arteriogenesis. Circ Res (2007) 1.54
Impaired trafficking of mutants of lysosomal glucocerebrosidase in Gaucher's disease. Int J Biochem Cell Biol (2005) 1.50
The T-box transcription factor Tbx18 maintains the separation of anterior and posterior somite compartments. Genes Dev (2004) 1.46
Apical sorting by galectin-3-dependent glycoprotein clustering. Traffic (2007) 1.45
Analysis of sequence variability of the bovine prion protein gene (PRNP) in German cattle breeds. Neurogenetics (2004) 1.43
Bovine prion protein gene (PRNP) promoter polymorphisms modulate PRNP expression and may be responsible for differences in bovine spongiform encephalopathy susceptibility. J Biol Chem (2005) 1.40
Deglycosylation by small intestinal epithelial cell beta-glucosidases is a critical step in the absorption and metabolism of dietary flavonoid glycosides in humans. Eur J Nutr (2003) 1.40
Divergent functions and distinct localization of the Notch ligands DLL1 and DLL3 in vivo. J Cell Biol (2007) 1.39
A genome-wide association study reveals loci influencing height and other conformation traits in horses. PLoS One (2012) 1.39
The role of galectins in protein trafficking. Traffic (2009) 1.37
Endocytotic segregation of gliadin peptide 31-49 in enterocytes. Gut (2009) 1.34
Transcription factor IRF4 determines germinal center formation through follicular T-helper cell differentiation. Proc Natl Acad Sci U S A (2012) 1.32
Feedback loops comprising Dll1, Dll3 and Mesp2, and differential involvement of Psen1 are essential for rostrocaudal patterning of somites. Development (2003) 1.32
A critical role for notch signaling in the formation of cholangiocellular carcinomas. Cancer Cell (2013) 1.30
Transcriptional oscillation of lunatic fringe is essential for somitogenesis. Genes Dev (2003) 1.29
Genome-wide analysis reveals selection for important traits in domestic horse breeds. PLoS Genet (2013) 1.26
Structural basis for substrate selectivity in human maltase-glucoamylase and sucrase-isomaltase N-terminal domains. J Biol Chem (2010) 1.24
Both cleavage products of the mCLCA3 protein are secreted soluble proteins. J Biol Chem (2006) 1.22
Genetic diversity in the modern horse illustrated from genome-wide SNP data. PLoS One (2013) 1.18
Annonacin, a natural mitochondrial complex I inhibitor, causes tau pathology in cultured neurons. J Neurosci (2007) 1.18
The mouse homeobox gene Not is required for caudal notochord development and affected by the truncate mutation. Genes Dev (2004) 1.17
Spongiform encephalopathy in a miniature zebu. Emerg Infect Dis (2006) 1.17
The mouse homeobox gene Noto regulates node morphogenesis, notochordal ciliogenesis, and left right patterning. Proc Natl Acad Sci U S A (2007) 1.17
Expression of Msgn1 in the presomitic mesoderm is controlled by synergism of WNT signalling and Tbx6. EMBO Rep (2007) 1.17
Serial translocation by means of circular intermediates underlies colour sidedness in cattle. Nature (2012) 1.16
The retention factor p11 confers an endoplasmic reticulum-localization signal to the potassium channel TASK-1. Traffic (2006) 1.15
LUPA: a European initiative taking advantage of the canine genome architecture for unravelling complex disorders in both human and dogs. Vet J (2011) 1.15
LGI2 truncation causes a remitting focal epilepsy in dogs. PLoS Genet (2011) 1.14
Identification of the bovine Arachnomelia mutation by massively parallel sequencing implicates sulfite oxidase (SUOX) in bone development. PLoS Genet (2010) 1.13
PRNP promoter polymorphisms are associated with BSE susceptibility in Swiss and German cattle. BMC Genet (2007) 1.13
Lunatic Fringe-mediated Notch signaling is required for lung alveogenesis. Am J Physiol Lung Cell Mol Physiol (2009) 1.12
Role of the Notch ligand Delta1 in embryonic and adult mouse epidermis. J Invest Dermatol (2007) 1.11
Mutations in MITF and PAX3 cause "splashed white" and other white spotting phenotypes in horses. PLoS Genet (2012) 1.11
The mouse rib-vertebrae mutation is a hypomorphic Tbx6 allele. Mech Dev (2002) 1.08
Endogenous vascular hydrogen peroxide regulates arteriolar tension in vivo. Circulation (2005) 1.08
Compound heterozygous mutations affect protein folding and function in patients with congenital sucrase-isomaltase deficiency. Gastroenterology (2008) 1.07
Osteogenesis imperfecta in dachshunds. Vet Rec (2013) 1.07
Noncyclic Notch activity in the presomitic mesoderm demonstrates uncoupling of somite compartmentalization and boundary formation. Genes Dev (2008) 1.06
The prostate specific membrane antigen regulates the expression of IL-6 and CCL5 in prostate tumour cells by activating the MAPK pathways. PLoS One (2009) 1.06
Congenital syndactyly in cattle: four novel mutations in the low density lipoprotein receptor-related protein 4 gene (LRP4). BMC Genet (2007) 1.06
An unusual splice defect in the mitofusin 2 gene (MFN2) is associated with degenerative axonopathy in Tyrolean Grey cattle. PLoS One (2011) 1.05
Specification of vertebral identity is coupled to Notch signalling and the segmentation clock. Development (2004) 1.05
Apical cargo traverses endosomal compartments on the passage to the cell surface. Traffic (2008) 1.05
A single point mutation within the ED1 gene disrupts correct splicing at two different splice sites and leads to anhidrotic ectodermal dysplasia in cattle. J Mol Med (Berl) (2002) 1.04
Critical involvement of hydrogen peroxide in exercise-induced up-regulation of endothelial NO synthase. Cardiovasc Res (2005) 1.04
Molecular basis for the action of the collagen-specific chaperone Hsp47/SERPINH1 and its structure-specific client recognition. Proc Natl Acad Sci U S A (2012) 1.04
Domains in biological membranes. Exp Cell Res (2009) 1.03
Alpha-kinase 1, a new component in apical protein transport. J Biol Chem (2005) 1.02
A genome-wide association study to detect QTL for commercially important traits in Swiss Large White boars. PLoS One (2013) 1.02
Novel mutations in the human sucrase-isomaltase gene (SI) that cause congenital carbohydrate malabsorption. Hum Mutat (2006) 1.01
Allelic heterogeneity at the equine KIT locus in dominant white (W) horses. PLoS Genet (2007) 1.01
Mesodermal and neuronal retinoids regulate the induction and maintenance of limb innervating spinal motor neurons. Dev Biol (2006) 1.00
Loss of galectin-3 impairs membrane polarisation of mouse enterocytes in vivo. J Cell Sci (2008) 1.00
Dll1 and Dll4 function sequentially in the retina and pV2 domain of the spinal cord to regulate neurogenesis and create cell diversity. Dev Biol (2009) 1.00
Fine-mapping and mutation analysis of TRPM1: a candidate gene for leopard complex (LP) spotting and congenital stationary night blindness in horses. Brief Funct Genomics (2010) 1.00
Single linkage group per chromosome genetic linkage map for the horse, based on two three-generation, full-sibling, crossbred horse reference families. Genomics (2005) 0.99
Distinct cytoskeletal tracks direct individual vesicle populations to the apical membrane of epithelial cells. Curr Biol (2003) 0.99
Annexin II is required for apical transport in polarized epithelial cells. J Biol Chem (2003) 0.99
A COL11A2 mutation in Labrador retrievers with mild disproportionate dwarfism. PLoS One (2013) 0.99
Galectin-3, a novel centrosome-associated protein, required for epithelial morphogenesis. Mol Biol Cell (2009) 0.98
The mutation causing the black-and-tan pigmentation phenotype of Mangalitza pigs maps to the porcine ASIP locus but does not affect its coding sequence. Mamm Genome (2006) 0.98
Disruption of segmental neural crest migration and ephrin expression in delta-1 null mice. Dev Biol (2002) 0.98
Identification of a missense mutation in the bovine ATP2A1 gene in congenital pseudomyotonia of Chianina cattle: an animal model of human Brody disease. Genomics (2008) 0.95
CD27+ B cells in human lymphatic organs: re-evaluating the splenic marginal zone. Immunology (2005) 0.95
Evidence for a retroviral insertion in TRPM1 as the cause of congenital stationary night blindness and leopard complex spotting in the horse. PLoS One (2013) 0.95
Transcoronary delivery of bone marrow cells to the infarcted murine myocardium: feasibility, cellular kinetics, and improvement in cardiac function. Basic Res Cardiol (2006) 0.94
Biochemical typing of pathological prion protein in aging cattle with BSE. Virol J (2009) 0.94
A novel sorting signal for intracellular localization is present in the S protein of a porcine coronavirus but absent from severe acute respiratory syndrome-associated coronavirus. J Biol Chem (2004) 0.93
Trafficking of galectin-3 through endosomal organelles of polarized and non-polarized cells. Eur J Cell Biol (2010) 0.93
Neuropeptide Y (NPY) cleaving enzymes: structural and functional homologues of dipeptidyl peptidase 4. Peptides (2007) 0.93
A noncoding melanophilin gene (MLPH) SNP at the splice donor of exon 1 represents a candidate causal mutation for coat color dilution in dogs. J Hered (2007) 0.93
Binding of Par-4 to the actin cytoskeleton is essential for Par-4/Dlk-mediated apoptosis. Exp Cell Res (2005) 0.93