Published in Dev Cell on December 01, 2007
The endoderm of the mouse embryo arises by dynamic widespread intercalation of embryonic and extraembryonic lineages. Dev Cell (2008) 3.08
Making a commitment: cell lineage allocation and axis patterning in the early mouse embryo. Nat Rev Mol Cell Biol (2009) 2.86
Morphogenesis of the node and notochord: the cellular basis for the establishment and maintenance of left-right asymmetry in the mouse. Dev Dyn (2008) 1.50
Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives. BMC Genomics (2008) 1.35
Intraflagellar transport protein 172 is essential for primary cilia formation and plays a vital role in patterning the mammalian brain. Dev Biol (2008) 1.30
Cellular dynamics in the early mouse embryo: from axis formation to gastrulation. Curr Opin Genet Dev (2010) 1.30
Phenotypic annotation of the mouse X chromosome. Genome Res (2010) 1.26
Live-imaging fluorescent proteins in mouse embryos: multi-dimensional, multi-spectral perspectives. Trends Biotechnol (2009) 1.25
Tracing notochord-derived cells using a Noto-cre mouse: implications for intervertebral disc development. Dis Model Mech (2011) 1.12
The novel mouse mutant, chuzhoi, has disruption of Ptk7 protein and exhibits defects in neural tube, heart and lung development and abnormal planar cell polarity in the ear. BMC Dev Biol (2010) 1.06
Chato, a KRAB zinc-finger protein, regulates convergent extension in the mouse embryo. Development (2008) 1.06
Forming patterns in development without morphogen gradients: scattered differentiation and sorting out. Cold Spring Harb Perspect Biol (2009) 1.06
Forces generated by cell intercalation tow epidermal sheets in mammalian tissue morphogenesis. Dev Cell (2014) 1.01
RFX2 is essential in the ciliated organ of asymmetry and an RFX2 transgene identifies a population of ciliated cells sufficient for fluid flow. Dev Biol (2011) 1.01
Role of the gut endoderm in relaying left-right patterning in mice. PLoS Biol (2012) 0.97
Foxa1 and Foxa2 are required for formation of the intervertebral discs. PLoS One (2013) 0.92
Left-right patterning in the mouse requires Epb4.1l5-dependent morphogenesis of the node and midline. Dev Biol (2010) 0.91
Bridging the Gap: Understanding Embryonic Intervertebral Disc Development. Cell Dev Biol (2012) 0.91
Wnt signaling maintains the notochord fate for progenitor cells and supports the posterior extension of the notochord. Mech Dev (2009) 0.90
Zic3 is required in the migrating primitive streak for node morphogenesis and left-right patterning. Hum Mol Genet (2013) 0.89
Mechanisms of left-right asymmetry and patterning: driver, mediator and responder. F1000Prime Rep (2014) 0.88
Ex vivo time-lapse confocal imaging of the mouse embryo aorta. Nat Protoc (2011) 0.88
The conserved role and divergent regulation of foxa, a pan-eumetazoan developmental regulatory gene. Dev Biol (2010) 0.88
Differentiation patterns of embryonic stem cells in two- versus three-dimensional culture. Cells Tissues Organs (2013) 0.87
Live imaging of whole mouse embryos during gastrulation: migration analyses of epiblast and mesodermal cells. PLoS One (2013) 0.84
Salient features of the ciliated organ of asymmetry. Bioarchitecture (2014) 0.84
Shape and position of the node and notochord along the bilateral plane of symmetry are regulated by cell-extracellular matrix interactions. Biol Open (2014) 0.84
Venus trap in the mouse embryo reveals distinct molecular dynamics underlying specification of first embryonic lineages. EMBO Rep (2015) 0.84
Coordination of cell differentiation and migration in mathematical models of caudal embryonic axis extension. PLoS One (2011) 0.83
Analysis of the asymmetrically expressed Ablim1 locus reveals existence of a lateral plate Nodal-independent left sided signal and an early, left-right independent role for nodal flow. BMC Dev Biol (2010) 0.83
Position-dependent plasticity of distinct progenitor types in the primitive streak. Elife (2016) 0.83
Imaging mouse embryonic development. Methods Enzymol (2010) 0.83
Exploiting notochord cells for stem cell-based regeneration of the intervertebral disc. J Cell Commun Signal (2011) 0.82
The zebrafish tailbud contains two independent populations of midline progenitor cells that maintain long-term germ layer plasticity and differentiate in response to local signaling cues. Development (2015) 0.81
Mixl1 localizes to putative axial stem cell reservoirs and their posterior descendants in the mouse embryo. Gene Expr Patterns (2014) 0.81
Ex utero culture and live imaging of mouse embryos. Methods Mol Biol (2011) 0.81
Generation of knock-in mice that express nuclear enhanced green fluorescent protein and tamoxifen-inducible Cre recombinase in the notochord from Foxa2 and T loci. Genesis (2013) 0.81
Wnt5a and Wnt11 regulate mammalian anterior-posterior axis elongation. Development (2015) 0.80
Genetic dissection of ventral folding morphogenesis in mouse: embryonic visceral endoderm-supplied BMP2 positions head and heart. Curr Opin Genet Dev (2013) 0.79
Lhx1 functions together with Otx2, Foxa2, and Ldb1 to govern anterior mesendoderm, node, and midline development. Genes Dev (2015) 0.79
Isolation and characterization of node/notochord-like cells from mouse embryonic stem cells. Stem Cells Dev (2011) 0.79
Two deltaC splice-variants have distinct signaling abilities during somitogenesis and midline patterning. Dev Biol (2008) 0.78
Development of head organizer of the mouse embryo depends on a high level of mitochondrial metabolism. Dev Biol (2010) 0.78
Imaging morphogenesis. Philos Trans R Soc Lond B Biol Sci (2017) 0.78
The Dynamics of Morphogenesis in the Early Mouse Embryo. Cold Spring Harb Perspect Biol (2014) 0.78
Transcriptional control of left-right patterning in cardiac development. Pediatr Cardiol (2010) 0.78
Fibronectin contributes to notochord intercalation in the invertebrate chordate, Ciona intestinalis. Evodevo (2016) 0.77
Notochord morphogenesis in mice: Current understanding & open questions. Dev Dyn (2016) 0.76
Combined PDGFR and HDAC Inhibition Overcomes PTEN Disruption in Chordoma. PLoS One (2015) 0.76
Foxa2 mediates critical functions of prechordal plate in patterning and morphogenesis and is cell autonomously required for early ventral endoderm morphogenesis. Biol Open (2012) 0.76
Computational modeling reveals that a combination of chemotaxis and differential adhesion leads to robust cell sorting during tissue patterning. PLoS One (2014) 0.75
How the sea squirt nucleus tells mesoderm not to be endoderm. Dev Cell (2010) 0.75
Putative oncogene Brachyury (T) is essential to specify cell fate but dispensable for notochord progenitor proliferation and EMT. Proc Natl Acad Sci U S A (2016) 0.75
Functional and evolutionary insights from the Ciona notochord transcriptome. Development (2017) 0.75
Characterization of human embryonic stem cell lines by the International Stem Cell Initiative. Nat Biotechnol (2007) 9.36
Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis. Nature (2007) 9.09
A mouse for all reasons. Cell (2007) 9.01
Control of effector CD8+ T cell function by the transcription factor Eomesodermin. Science (2003) 7.75
Interaction between Oct3/4 and Cdx2 determines trophectoderm differentiation. Cell (2005) 7.30
Global survey of organ and organelle protein expression in mouse: combined proteomic and transcriptomic profiling. Cell (2006) 5.72
The notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis. Cell (2009) 5.33
The Hippo signaling pathway components Lats and Yap pattern Tead4 activity to distinguish mouse trophectoderm from inner cell mass. Dev Cell (2009) 5.19
Endothelial cells and VEGF in vascular development. Nature (2005) 4.92
Cdx2 is required for correct cell fate specification and differentiation of trophectoderm in the mouse blastocyst. Development (2005) 4.89
Early lineage segregation between epiblast and primitive endoderm in mouse blastocysts through the Grb2-MAPK pathway. Dev Cell (2006) 4.77
The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-β-SMAD pathway. Dev Cell (2010) 4.59
Retinoid signaling determines germ cell fate in mice. Science (2006) 4.17
Dosage-sensitive requirement for mouse Dll4 in artery development. Genes Dev (2004) 4.14
Baf60c is essential for function of BAF chromatin remodelling complexes in heart development. Nature (2004) 4.09
Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage. Nat Biotechnol (2011) 3.97
A public gene trap resource for mouse functional genomics. Nat Genet (2004) 3.96
Molecular profiling of non-small cell lung cancer and correlation with disease-free survival. Cancer Res (2002) 3.68
The International Gene Trap Consortium Website: a portal to all publicly available gene trap cell lines in mouse. Nucleic Acids Res (2006) 3.40
Wnt3a plays a major role in the segmentation clock controlling somitogenesis. Dev Cell (2003) 3.15
Spatial and temporal patterns of ERK signaling during mouse embryogenesis. Development (2003) 3.14
Imprinted X-inactivation in extra-embryonic endoderm cell lines from mouse blastocysts. Development (2005) 2.91
Deletion of the selection cassette, but not cis-acting elements, in targeted Flk1-lacZ allele reveals Flk1 expression in multipotent mesodermal progenitors. Blood (2005) 2.76
Notch2, but not Notch1, is required for proximal fate acquisition in the mammalian nephron. Development (2007) 2.70
The mammalian gene function resource: the International Knockout Mouse Consortium. Mamm Genome (2012) 2.65
Ethics. The ISSCR guidelines for human embryonic stem cell research. Science (2007) 2.62
FGF signal-dependent segregation of primitive endoderm and epiblast in the mouse blastocyst. Development (2010) 2.60
Isolation of human iPS cells using EOS lentiviral vectors to select for pluripotency. Nat Methods (2009) 2.51
The role of FGF/Erk signaling in pluripotent cells. Development (2010) 2.40
The Notch ligands DLL1 and JAG2 act synergistically to regulate hair cell development in the mammalian inner ear. Development (2005) 2.36
Transgenic RNA interference in ES cell-derived embryos recapitulates a genetic null phenotype. Nat Biotechnol (2003) 2.34
Establishment of endoderm progenitors by SOX transcription factor expression in human embryonic stem cells. Cell Stem Cell (2008) 2.31
Cdx2 acts downstream of cell polarization to cell-autonomously promote trophectoderm fate in the early mouse embryo. Dev Biol (2007) 2.26
A new partner for the international knockout mouse consortium. Cell (2007) 2.23
Genome-wide analysis of mouse transcripts using exon microarrays and factor graphs. Nat Genet (2005) 2.15
Evidence for novel fate of Flk1+ progenitor: contribution to muscle lineage. Genesis (2003) 2.14
Argyrin a reveals a critical role for the tumor suppressor protein p27(kip1) in mediating antitumor activities in response to proteasome inhibition. Cancer Cell (2008) 2.12
Ubiquitous transgene expression and Cre-based recombination driven by the ubiquitin promoter in zebrafish. Development (2011) 2.11
Cell and molecular regulation of the mouse blastocyst. Dev Dyn (2006) 2.10
Vascular endothelial growth factor a signaling in the podocyte-endothelial compartment is required for mesangial cell migration and survival. J Am Soc Nephrol (2006) 2.10
Cdx2 is essential for axial elongation in mouse development. Proc Natl Acad Sci U S A (2004) 2.08
DLL1-mediated Notch activation regulates endothelial identity in mouse fetal arteries. Blood (2009) 2.07
Proneural bHLH and Brn proteins coregulate a neurogenic program through cooperative binding to a conserved DNA motif. Dev Cell (2006) 2.06
Mouse embryonic chimeras: tools for studying mammalian development. Development (2003) 2.06
Deletion of Notch1 converts pro-T cells to dendritic cells and promotes thymic B cells by cell-extrinsic and cell-intrinsic mechanisms. Immunity (2008) 2.05
Gata3 regulates trophoblast development downstream of Tead4 and in parallel to Cdx2. Development (2010) 2.05
Stem cells. Setting standards for human embryonic stem cells. Science (2003) 1.95
Krüppel-like factor 5 is essential for blastocyst development and the normal self-renewal of mouse ESCs. Cell Stem Cell (2008) 1.94
A Gja1 missense mutation in a mouse model of oculodentodigital dysplasia. Development (2005) 1.93
PRISM, a generic large scale proteomic investigation strategy for mammals. Mol Cell Proteomics (2003) 1.91
FGFR1 is independently required in both developing mid- and hindbrain for sustained response to isthmic signals. EMBO J (2003) 1.85
Making the blastocyst: lessons from the mouse. J Clin Invest (2010) 1.85
FGF signaling through FGFR1 is required for olfactory bulb morphogenesis. Development (2003) 1.83
New roles for model genetic organisms in understanding and treating human disease: report from the 2006 Genetics Society of America meeting. Genetics (2006) 1.83
Gene expression profiling of embryo-derived stem cells reveals candidate genes associated with pluripotency and lineage specificity. Genome Res (2002) 1.77
Premature myogenic differentiation and depletion of progenitor cells cause severe muscle hypotrophy in Delta1 mutants. Proc Natl Acad Sci U S A (2006) 1.76
Transcriptome analysis of mouse stem cells and early embryos. PLoS Biol (2003) 1.75
Three-dimensional analysis of vascular development in the mouse embryo. PLoS One (2008) 1.74
WNT signaling, in synergy with T/TBX6, controls Notch signaling by regulating Dll1 expression in the presomitic mesoderm of mouse embryos. Genes Dev (2004) 1.74
Foxh1 is essential for development of the anterior heart field. Dev Cell (2004) 1.74
Directed differentiation of human pluripotent stem cells into mature airway epithelia expressing functional CFTR protein. Nat Biotechnol (2012) 1.73
Expression of Notch pathway components in fetal and adult mouse small intestine. Gene Expr Patterns (2002) 1.72
Comparison of defined culture systems for feeder cell free propagation of human embryonic stem cells. In Vitro Cell Dev Biol Anim (2010) 1.70
Erythropoietin preserves the endothelial differentiation capacity of cardiac progenitor cells and reduces heart failure during anticancer therapies. Cell Stem Cell (2011) 1.67
Distinct histone modifications in stem cell lines and tissue lineages from the early mouse embryo. Proc Natl Acad Sci U S A (2010) 1.64
Combinatorial effects of Flk1 and Tal1 on vascular and hematopoietic development in the mouse. Genes Dev (2003) 1.62
Ascl1 and Gsh1/2 control inhibitory and excitatory cell fate in spinal sensory interneurons. Nat Neurosci (2006) 1.61
Notch alters VEGF responsiveness in human and murine endothelial cells by direct regulation of VEGFR-3 expression. J Clin Invest (2007) 1.60
Global chromatin architecture reflects pluripotency and lineage commitment in the early mouse embryo. PLoS One (2010) 1.60
Notch ligand Delta-like 1 is essential for postnatal arteriogenesis. Circ Res (2007) 1.54
Bone sialoprotein plays a functional role in bone formation and osteoclastogenesis. J Exp Med (2008) 1.54
The Hippo pathway member Nf2 is required for inner cell mass specification. Curr Biol (2013) 1.52
Integrated proteomic and transcriptomic profiling of mouse lung development and Nmyc target genes. Mol Syst Biol (2007) 1.50
Stroma provides an intestinal stem cell niche in the absence of epithelial Wnts. Development (2014) 1.49
Efficient generation of germ line transmitting chimeras from C57BL/6N ES cells by aggregation with outbred host embryos. PLoS One (2010) 1.47
The T-box transcription factor Tbx18 maintains the separation of anterior and posterior somite compartments. Genes Dev (2004) 1.46
Heparan sulfation-dependent fibroblast growth factor signaling maintains embryonic stem cells primed for differentiation in a heterogeneous state. Stem Cells (2010) 1.44
Divergent functions and distinct localization of the Notch ligands DLL1 and DLL3 in vivo. J Cell Biol (2007) 1.39
Dynamic expression of Lrp2 pathway members reveals progressive epithelial differentiation of primitive endoderm in mouse blastocyst. Dev Biol (2007) 1.39
Cell-surface proteomics identifies lineage-specific markers of embryo-derived stem cells. Dev Cell (2012) 1.37
Alternative induced pluripotent stem cell characterization criteria for in vitro applications. Cell Stem Cell (2009) 1.36
Distinct functions of BMP4 during different stages of mouse ES cell neural commitment. Development (2010) 1.36
Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives. BMC Genomics (2008) 1.35
Bloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screening. Dis Model Mech (2013) 1.34
Porcupine homolog is required for canonical Wnt signaling and gastrulation in mouse embryos. Dev Biol (2011) 1.33
Feedback loops comprising Dll1, Dll3 and Mesp2, and differential involvement of Psen1 are essential for rostrocaudal patterning of somites. Development (2003) 1.32
The Sweet Pee model for Sglt2 mutation. J Am Soc Nephrol (2011) 1.32
Implementing large-scale ENU mutagenesis screens in North America. Genetica (2004) 1.31
A critical role for notch signaling in the formation of cholangiocellular carcinomas. Cancer Cell (2013) 1.30
Transcriptional oscillation of lunatic fringe is essential for somitogenesis. Genes Dev (2003) 1.29
The role of chordin/Bmp signals in mammalian pharyngeal development and DiGeorge syndrome. Development (2003) 1.29
Phenotypic annotation of the mouse X chromosome. Genome Res (2010) 1.26
Baf60c is a nuclear Notch signaling component required for the establishment of left-right asymmetry. Proc Natl Acad Sci U S A (2007) 1.26
The mouse embryo autonomously acquires anterior-posterior polarity at implantation. Dev Cell (2006) 1.25
Vascular endothelial growth factor directly inhibits primitive neural stem cell survival but promotes definitive neural stem cell survival. J Neurosci (2006) 1.24
Comparative systems biology of human and mouse as a tool to guide the modeling of human placental pathology. Mol Syst Biol (2009) 1.23
Zfp206 regulates ES cell gene expression and differentiation. Nucleic Acids Res (2006) 1.22
Mouse trophoblast stem cells. Methods Mol Med (2006) 1.19
Disorganized epithelial polarity and excess trophectoderm cell fate in preimplantation embryos lacking E-cadherin. Development (2010) 1.18