Published in J Biol Chem on October 19, 2002
PKC and the control of localized signal dynamics. Nat Rev Mol Cell Biol (2010) 2.41
Small GTPase Rab21 regulates cell adhesion and controls endosomal traffic of beta1-integrins. J Cell Biol (2006) 2.41
Human tumstatin and human endostatin exhibit distinct antiangiogenic activities mediated by alpha v beta 3 and alpha 5 beta 1 integrins. Proc Natl Acad Sci U S A (2003) 2.28
PKD1/PKCmu promotes alphavbeta3 integrin recycling and delivery to nascent focal adhesions. EMBO J (2004) 1.69
Human alpha1 type IV collagen NC1 domain exhibits distinct antiangiogenic activity mediated by alpha1beta1 integrin. J Clin Invest (2005) 1.66
Genetic control of the innate immune response. BMC Immunol (2003) 1.50
The MEK1 scaffolding protein MP1 regulates cell spreading by integrating PAK1 and Rho signals. Mol Cell Biol (2005) 1.34
Analysis of foot-and-mouth disease virus internalization events in cultured cells. J Virol (2005) 1.17
Giving off mixed signals--distinct functions of alpha5beta1 and alphavbeta3 integrins in regulating cell behaviour. IUBMB Life (2009) 1.14
An extracellular signal-regulated kinase 1- and 2-dependent program of chromatin trafficking of c-Fos and Fra-1 is required for cyclin D1 expression during cell cycle reentry. Mol Cell Biol (2004) 1.12
Interaction of paxillin with poly(A)-binding protein 1 and its role in focal adhesion turnover and cell migration. Mol Cell Biol (2005) 1.08
FAK and p38-MAP kinase-dependent activation of apoptosis and caspase-3 in retinal endothelial cells by alpha1(IV)NC1. Invest Ophthalmol Vis Sci (2009) 0.91
Beta 1-integrin-c-Met cooperation reveals an inside-in survival signalling on autophagy-related endomembranes. Nat Commun (2016) 0.87
A novel cell line and xenograft model of ampulla of Vater adenocarcinoma. Virchows Arch (2003) 0.83
Integrin-mediated cell-matrix interaction in physiological and pathological blood vessel formation. J Oncol (2011) 0.79
Small G proteins Rac1 and Ras regulate serine/threonine protein phosphatase 5 (PP5)·extracellular signal-regulated kinase (ERK) complexes involved in the feedback regulation of Raf1. J Biol Chem (2013) 0.79
Stromal transcriptional profiles reveal hierarchies of anatomical site, serum response and disease and identify disease specific pathways. PLoS One (2015) 0.78
Mitochondrial Dysfunction in the Liver and Antiphospholipid Antibody Production Precede Disease Onset and Respond to Rapamycin in Lupus-Prone Mice. Arthritis Rheumatol (2016) 0.76
Job-splitting among integrins. Nat Cell Biol (2013) 0.76
Rosette nanotubes inhibit bovine neutrophil chemotaxis. Vet Res (2010) 0.75
RABGTPases in MT1-MMP trafficking and cell invasion: Physiology versus pathology. Small GTPases (2015) 0.75
Mutant p53 drives invasion by promoting integrin recycling. Cell (2009) 4.75
Rab25 associates with alpha5beta1 integrin to promote invasive migration in 3D microenvironments. Dev Cell (2007) 3.84
Integrins: masters and slaves of endocytic transport. Nat Rev Mol Cell Biol (2009) 3.52
Integrin trafficking and the control of cell migration. Traffic (2006) 2.89
Stimulation of tumor growth and angiogenesis by low concentrations of RGD-mimetic integrin inhibitors. Nat Med (2009) 2.73
Rab-coupling protein coordinates recycling of alpha5beta1 integrin and EGFR1 to promote cell migration in 3D microenvironments. J Cell Biol (2008) 2.61
p53 and its mutants in tumor cell migration and invasion. J Cell Biol (2011) 2.49
Endocytic recycling pathways: emerging regulators of cell migration. Curr Opin Cell Biol (2006) 2.48
alpha v beta3 and alpha5beta1 integrin recycling pathways dictate downstream Rho kinase signaling to regulate persistent cell migration. J Cell Biol (2007) 2.31
P-Rex1 is required for efficient melanoblast migration and melanoma metastasis. Nat Commun (2011) 2.18
Neuropilin-1/GIPC1 signaling regulates alpha5beta1 integrin traffic and function in endothelial cells. PLoS Biol (2009) 2.16
RhoB and actin polymerization coordinate Src activation with endosome-mediated delivery to the membrane. Dev Cell (2004) 2.13
Mechanisms of integrin activation and trafficking. Curr Opin Cell Biol (2011) 2.00
Protein kinase B/Akt acts via glycogen synthase kinase 3 to regulate recycling of alpha v beta 3 and alpha 5 beta 1 integrins. Mol Cell Biol (2004) 1.93
VEGF regulates the mobilization of VEGFR2/KDR from an intracellular endothelial storage compartment. Blood (2006) 1.87
Rab25 and CLIC3 collaborate to promote integrin recycling from late endosomes/lysosomes and drive cancer progression. Dev Cell (2011) 1.87
Distinct roles of talin and kindlin in regulating integrin α5β1 function and trafficking. Curr Biol (2012) 1.86
PKD1/PKCmu promotes alphavbeta3 integrin recycling and delivery to nascent focal adhesions. EMBO J (2004) 1.69
Cyclic AMP-dependent kinase regulates Raf-1 kinase mainly by phosphorylation of serine 259. Mol Cell Biol (2002) 1.63
Autocrine-mediated activation of STAT3 correlates with cell proliferation in breast carcinoma lines. J Biol Chem (2002) 1.59
N-WASP coordinates the delivery and F-actin-mediated capture of MT1-MMP at invasive pseudopods. J Cell Biol (2012) 1.45
Basic fibroblast growth factor activates the MAPK and NFkappaB pathways that converge on Elk-1 to control production of matrix metalloproteinase-13 by human adult articular chondrocytes. J Biol Chem (2007) 1.44
Paxillin associates with poly(A)-binding protein 1 at the dense endoplasmic reticulum and the leading edge of migrating cells. J Biol Chem (2001) 1.31
Bacterial N-acylhomoserine lactone-induced apoptosis in breast carcinoma cells correlated with down-modulation of STAT3. Oncogene (2004) 1.31
B-Raf acts via the ROCKII/LIMK/cofilin pathway to maintain actin stress fibers in fibroblasts. Mol Cell Biol (2004) 1.28
PAK1 primes MEK1 for phosphorylation by Raf-1 kinase during cross-cascade activation of the ERK pathway. Oncogene (2002) 1.27
Epigenetic inactivation of protein kinase D1 in gastric cancer and its role in gastric cancer cell migration and invasion. Carcinogenesis (2008) 1.24
Diacylglycerol kinase α controls RCP-dependent integrin trafficking to promote invasive migration. J Cell Biol (2012) 1.21
Inducible gene deletion reveals different roles for B-Raf and Raf-1 in B-cell antigen receptor signalling. EMBO J (2002) 1.19
Integrin trafficking at a glance. J Cell Sci (2012) 1.19
Mitogen-induced recruitment of ERK and MSK to SRE promoter complexes by ternary complex factor Elk-1. Nucleic Acids Res (2008) 1.18
Rab11 and its effector Rab coupling protein contribute to the trafficking of beta 1 integrins during axon growth in adult dorsal root ganglion neurons and PC12 cells. J Neurosci (2010) 1.15
Modulation of gene expression and tumor cell growth by redox modification of STAT3. Cancer Res (2010) 1.14
RCP-driven α5β1 recycling suppresses Rac and promotes RhoA activity via the RacGAP1-IQGAP1 complex. J Cell Biol (2013) 1.13
Rab5c promotes AMAP1-PRKD2 complex formation to enhance β1 integrin recycling in EGF-induced cancer invasion. J Cell Biol (2012) 1.12
Class I Rab11-family interacting proteins are binding targets for the Rab14 GTPase. Biol Cell (2009) 1.11
Interaction of paxillin with poly(A)-binding protein 1 and its role in focal adhesion turnover and cell migration. Mol Cell Biol (2005) 1.08
Elevated activity of STAT3C due to higher DNA binding affinity of phosphotyrosine dimer rather than covalent dimer formation. J Biol Chem (2006) 1.08
ARF6 directs axon transport and traffic of integrins and regulates axon growth in adult DRG neurons. J Neurosci (2012) 1.07
Mutant p53 regulates Dicer through p63-dependent and -independent mechanisms to promote an invasive phenotype. J Biol Chem (2013) 1.07
Aquaporin 2 promotes cell migration and epithelial morphogenesis. J Am Soc Nephrol (2012) 1.05
Genomic amplicons target vesicle recycling in breast cancer. J Clin Invest (2009) 1.04
A Raf-1 mutant that dissociates MEK/extracellular signal-regulated kinase activation from malignant transformation and differentiation but not proliferation. Mol Cell Biol (2003) 1.03
A STAT3 dimer formed by inter-chain disulphide bridging during oxidative stress. Biochem Biophys Res Commun (2004) 1.03
ERK2 drives tumour cell migration in three-dimensional microenvironments by suppressing expression of Rab17 and liprin-β2. J Cell Sci (2012) 1.01
hnRNP A2 regulates alternative mRNA splicing of TP53INP2 to control invasive cell migration. Cancer Res (2009) 0.97
VEGFR1 (Flt1) regulates Rab4 recycling to control fibronectin polymerization and endothelial vessel branching. Traffic (2009) 0.94
P-Rex1 cooperates with PDGFRβ to drive cellular migration in 3D microenvironments. PLoS One (2013) 0.91
PKD controls αvβ3 integrin recycling and tumor cell invasive migration through its substrate Rabaptin-5. Dev Cell (2012) 0.90
Dimer formation and conformational flexibility ensure cytoplasmic stability and nuclear accumulation of Elk-1. Nucleic Acids Res (2011) 0.82
Photoactivation approaches reveal a role for Rab11 in FGFR4 recycling and signalling. Traffic (2014) 0.80
New roles for lysosomal trafficking in morphogen gradient sensing. Sci Signal (2011) 0.78
The structural determinants of macrolide-actin binding: in silico insights. Biophys J (2007) 0.77
PU.1 is a major transcriptional activator of the tumour suppressor gene LIMD1. FEBS Lett (2011) 0.77
ERK phosphorylation of MED14 in promoter complexes during mitogen-induced gene activation by Elk-1. Nucleic Acids Res (2013) 0.77
Molecular dynamics simulations and in silico peptide ligand screening of the Elk-1 ETS domain. J Cheminform (2011) 0.76
Anomalous behaviour of the STAT3 binding site in the human c-myc P2 promoter. Biochem Biophys Res Commun (2007) 0.76
Post-translational control of ETS transcription factors: detection of modified factors at target gene promoters. Methods Mol Biol (2010) 0.75
Integration of protein kinases into transcription complexes: identifying components of immobilised in vitro pre-initiation complexes. Methods Mol Biol (2010) 0.75