Published in PLoS Genet on July 25, 2013
Chromatin-Remodelling Complex NURF Is Essential for Differentiation of Adult Melanocyte Stem Cells. PLoS Genet (2015) 1.43
The melanocyte lineage in development and disease. Development (2015) 1.11
DNA methylation and gene expression dynamics during spermatogonial stem cell differentiation in the early postnatal mouse testis. BMC Genomics (2015) 0.88
Stem Cells in Skin Regeneration, Wound Healing, and Their Clinical Applications. Int J Mol Sci (2015) 0.86
Melanoma: from melanocyte to genetic alterations and clinical options. Scientifica (Cairo) (2013) 0.85
Antagonistic cross-regulation between Sox9 and Sox10 controls an anti-tumorigenic program in melanoma. PLoS Genet (2015) 0.81
Premature graying as a consequence of compromised antioxidant activity in hair bulb melanocytes and their precursors. PLoS One (2014) 0.80
Genomic analysis reveals distinct mechanisms and functional classes of SOX10-regulated genes in melanocytes. Hum Mol Genet (2015) 0.78
Long-term expression pattern of melanocyte markers in light- and dark-pigmented dermo-epidermal cultured human skin substitutes. Pediatr Surg Int (2014) 0.76
Coexpression of SOX10/CD271 (p75(NTR)) and β-Galactosidase in Large to Giant Congenital Melanocytic Nevi of Pediatric Patients. Dermatopathology (Basel) (2014) 0.75
Neuroendocrine Cells of the Prostate Derive from the Neural Crest. J Biol Chem (2016) 0.75
Ectopic differentiation of melanocyte stem cells is influenced by genetic background. Pigment Cell Melanoma Res (2015) 0.75
Elevated Levels of SOX10 in Serum from Vitiligo and Melanoma Patients, Analyzed by Proximity Ligation Assay. PLoS One (2016) 0.75
MYSM1/2A-DUB is an epigenetic regulator in human melanoma and contributes to tumor cell growth. Oncotarget (2017) 0.75
The RhoJ-BAD signaling network: An Achilles' heel for BRAF mutant melanomas. PLoS Genet (2017) 0.75
Epilation induces hair and skin pigmentation through an EDN3/EDNRB-dependent regenerative response of melanocyte stem cells. Sci Rep (2017) 0.75
Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet (1999) 55.63
A comprehensive guide for the accurate classification of murine hair follicles in distinct hair cycle stages. J Invest Dermatol (2001) 6.12
A two-step mechanism for stem cell activation during hair regeneration. Cell Stem Cell (2009) 5.40
Mutations at the mouse microphthalmia locus are associated with defects in a gene encoding a novel basic-helix-loop-helix-zipper protein. Cell (1993) 5.00
The transcription factor Sox10 is a key regulator of peripheral glial development. Genes Dev (2001) 4.40
Dominant role of the niche in melanocyte stem-cell fate determination. Nature (2002) 4.05
Sox10 mutation disrupts neural crest development in Dom Hirschsprung mouse model. Nat Genet (1998) 3.51
Mechanisms of hair graying: incomplete melanocyte stem cell maintenance in the niche. Science (2004) 3.12
Genotoxic stress abrogates renewal of melanocyte stem cells by triggering their differentiation. Cell (2009) 2.99
SOX10 maintains multipotency and inhibits neuronal differentiation of neural crest stem cells. Neuron (2003) 2.98
A comprehensive guide for the recognition and classification of distinct stages of hair follicle morphogenesis. J Invest Dermatol (1999) 2.92
Mitf regulation of Dia1 controls melanoma proliferation and invasiveness. Genes Dev (2006) 2.87
Ocular retardation mouse caused by Chx10 homeobox null allele: impaired retinal progenitor proliferation and bipolar cell differentiation. Nat Genet (1996) 2.75
Interaction among SOX10, PAX3 and MITF, three genes altered in Waardenburg syndrome. Hum Mol Genet (2000) 2.63
Mitf cooperates with Rb1 and activates p21Cip1 expression to regulate cell cycle progression. Nature (2005) 2.44
Pax3 functions at a nodal point in melanocyte stem cell differentiation. Nature (2005) 2.37
Transcription factor hierarchy in Waardenburg syndrome: regulation of MITF expression by SOX10 and PAX3. Hum Genet (2000) 2.34
Mutation of the Sry-related Sox10 gene in Dominant megacolon, a mouse model for human Hirschsprung disease. Proc Natl Acad Sci U S A (1998) 2.15
Key roles for transforming growth factor beta in melanocyte stem cell maintenance. Cell Stem Cell (2010) 2.06
Coordinated activation of Wnt in epithelial and melanocyte stem cells initiates pigmented hair regeneration. Cell (2011) 1.92
MLANA/MART1 and SILV/PMEL17/GP100 are transcriptionally regulated by MITF in melanocytes and melanoma. Am J Pathol (2003) 1.90
MITF links differentiation with cell cycle arrest in melanocytes by transcriptional activation of INK4A. J Cell Biol (2004) 1.89
Notch signaling via Hes1 transcription factor maintains survival of melanoblasts and melanocyte stem cells. J Cell Biol (2006) 1.86
Characterization of melanocyte-specific inducible Cre recombinase transgenic mice. Genesis (2006) 1.85
Melanoblasts' proper location and timed differentiation depend on Notch/RBP-J signaling in postnatal hair follicles. J Invest Dermatol (2008) 1.83
Graying: gerontobiology of the hair follicle pigmentary unit. Exp Gerontol (2001) 1.75
Sorting out Sox10 functions in neural crest development. Bioessays (2006) 1.63
Transdifferentiation of the retina into pigmented cells in ocular retardation mice defines a new function of the homeodomain gene Chx10. Development (2004) 1.58
Multiple roles of Notch signaling in the regulation of epidermal development. Dev Cell (2008) 1.58
Myelin deficiencies in both the central and the peripheral nervous systems associated with a SOX10 mutation. Ann Neurol (1999) 1.54
SCF/c-kit signaling is required for cyclic regeneration of the hair pigmentation unit. FASEB J (2001) 1.54
Molecular characterization of melanocyte stem cells in their niche. Development (2005) 1.53
A molecular insight of Hes5-dependent inhibition of myelin gene expression: old partners and new players. EMBO J (2006) 1.49
Sox10 promotes the formation and maintenance of giant congenital naevi and melanoma. Nat Cell Biol (2012) 1.48
Sox10 is required for Schwann cell identity and progression beyond the immature Schwann cell stage. J Cell Biol (2010) 1.48
Notch1 and Notch2 receptors influence progressive hair graying in a dose-dependent manner. Dev Dyn (2007) 1.40
Transcription factors in melanocyte development: distinct roles for Pax-3 and Mitf. Mech Dev (2001) 1.39
The importance of having your SOX on: role of SOX10 in the development of neural crest-derived melanocytes and glia. Oncogene (2003) 1.37
An evolutionarily conserved intronic region controls the spatiotemporal expression of the transcription factor Sox10. BMC Dev Biol (2008) 1.31
Sox10 overexpression induces neural crest-like cells from all dorsoventral levels of the neural tube but inhibits differentiation. Dev Dyn (2005) 1.30
A role for ATF2 in regulating MITF and melanoma development. PLoS Genet (2010) 1.28
Sox10-Venus mice: a new tool for real-time labeling of neural crest lineage cells and oligodendrocytes. Mol Brain (2010) 1.27
Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered (1985) 1.26
Melanocyte-specific expression of dopachrome tautomerase is dependent on synergistic gene activation by the Sox10 and Mitf transcription factors. FEBS Lett (2004) 1.21
The tyrosinase enhancer is activated by Sox10 and Mitf in mouse melanocytes. Pigment Cell Res (2007) 1.18
The transcription factor Sox5 modulates Sox10 function during melanocyte development. Nucleic Acids Res (2008) 1.16
Direct interaction of Sox10 with the promoter of murine Dopachrome Tautomerase (Dct) and synergistic activation of Dct expression with Mitf. Pigment Cell Res (2004) 1.14
Pax3 and regulation of the melanocyte-specific tyrosinase-related protein-1 promoter. J Biol Chem (1999) 1.12
The microphthalmia-associated transcription factor requires SWI/SNF enzymes to activate melanocyte-specific genes. J Biol Chem (2006) 1.10
Functional characterization of melanocyte stem cells in hair follicles. J Invest Dermatol (2011) 1.09
A tissue-restricted cAMP transcriptional response: SOX10 modulates alpha-melanocyte-stimulating hormone-triggered expression of microphthalmia-associated transcription factor in melanocytes. J Biol Chem (2003) 1.07
Both Notch1 and Notch2 contribute to the regulation of melanocyte homeostasis. Pigment Cell Melanoma Res (2008) 1.06
Isolation and live imaging of enteric progenitors based on Sox10-Histone2BVenus transgene expression. Genesis (2011) 1.02
Interspecies difference in the regulation of melanocyte development by SOX10 and MITF. Proc Natl Acad Sci U S A (2006) 0.99
Indispensable role of Bcl2 in the development of the melanocyte stem cell. Dev Biol (2006) 0.98
Kit is expressed by epithelial cells in vivo. J Invest Dermatol (2003) 0.98
Fate of melanocytes during development of the hair follicle pigmentary unit. J Investig Dermatol Symp Proc (2003) 0.97
A conserved transcriptional enhancer that specifies Tyrp1 expression to melanocytes. Dev Biol (2006) 0.97
Sox10 controls migration of B16F10 melanoma cells through multiple regulatory target genes. PLoS One (2012) 0.97
Cochlear disorder associated with melanocyte anomaly in mice with a transgenic insertional mutation. Mol Cell Neurosci (1992) 0.95
Do hair bulb melanocytes undergo apoptosis during hair follicle regression (catagen)? J Invest Dermatol (1998) 0.93
Novel Tfap2-mediated control of soxE expression facilitated the evolutionary emergence of the neural crest. Development (2012) 0.91
The microphthalmia transcription factor (Mitf) controls expression of the ocular albinism type 1 gene: link between melanin synthesis and melanosome biogenesis. Mol Cell Biol (2004) 0.91
The fate of hair follicle melanocytes during the hair growth cycle. J Investig Dermatol Symp Proc (1999) 0.91
An iterative genetic and dynamical modelling approach identifies novel features of the gene regulatory network underlying melanocyte development. PLoS Genet (2011) 0.88
Genetic evidence does not support direct regulation of EDNRB by SOX10 in migratory neural crest and the melanocyte lineage. Mech Dev (2006) 0.86
Changes in different melanocyte populations during hair follicle involution (catagen). J Invest Dermatol (2005) 0.86
Peroxisome-proliferator-activated receptor-binding protein (PBP) is essential for the growth of active Notch4-immortalized mammary epithelial cells by activating SOX10 expression. Biochem J (2009) 0.84
Protective effect of Kit signaling for melanocyte stem cells against radiation-induced genotoxic stress. J Invest Dermatol (2011) 0.80
Neural crest cells retain their capability for multipotential differentiation even after lineage-restricted stages. Dev Dyn (2011) 0.80
Postnatal lineage mapping of follicular melanocytes with the Tyr::CreER(T) (2) transgene. Pigment Cell Melanoma Res (2012) 0.78
Bmi1 is essential for cerebellar development and is overexpressed in human medulloblastomas. Nature (2004) 4.82
Competing waves of oligodendrocytes in the forebrain and postnatal elimination of an embryonic lineage. Nat Neurosci (2005) 4.57
The Sox9 transcription factor determines glial fate choice in the developing spinal cord. Genes Dev (2003) 3.46
Functional analysis of Sox8 and Sox9 during sex determination in the mouse. Development (2004) 3.25
Terminal differentiation of myelin-forming oligodendrocytes depends on the transcription factor Sox10. Genes Dev (2002) 2.98
Instructive role of Wnt/beta-catenin in sensory fate specification in neural crest stem cells. Science (2004) 2.82
Molecular mechanism for distinct neurological phenotypes conveyed by allelic truncating mutations. Nat Genet (2004) 2.82
Melanoma mouse model implicates metabotropic glutamate signaling in melanocytic neoplasia. Nat Genet (2003) 2.67
Neural crest-derived cells with stem cell features can be traced back to multiple lineages in the adult skin. J Cell Biol (2006) 2.32
Frequent mutations in the MITF pathway in melanoma. Pigment Cell Melanoma Res (2009) 2.27
Gene targeting reveals a widespread role for the high-mobility-group transcription factor Sox11 in tissue remodeling. Mol Cell Biol (2004) 2.23
The exon junction complex component Magoh controls brain size by regulating neural stem cell division. Nat Neurosci (2010) 2.13
Linear clinical progression, independent of age of onset, in Niemann-Pick disease, type C. Am J Med Genet B Neuropsychiatr Genet (2010) 2.08
Human CD271-positive melanoma stem cells associated with metastasis establish tumor heterogeneity and long-term growth. Cancer Res (2011) 2.08
Mutation of melanosome protein RAB38 in chocolate mice. Proc Natl Acad Sci U S A (2002) 2.02
SOX9 is expressed in human fetal prostate epithelium and enhances prostate cancer invasion. Cancer Res (2008) 1.96
Lineage-specific requirements of beta-catenin in neural crest development. J Cell Biol (2002) 1.87
The Runx1/AML1 transcription factor selectively regulates development and survival of TrkA nociceptive sensory neurons. Nat Neurosci (2006) 1.83
Adult neurogenesis requires Smad4-mediated bone morphogenic protein signaling in stem cells. J Neurosci (2008) 1.81
The melanomas: a synthesis of epidemiological, clinical, histopathological, genetic, and biological aspects, supporting distinct subtypes, causal pathways, and cells of origin. Pigment Cell Melanoma Res (2011) 1.81
SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function. Dev Cell (2006) 1.79
A polymorphism in IRF4 affects human pigmentation through a tyrosinase-dependent MITF/TFAP2A pathway. Cell (2013) 1.75
Genomic copy number and expression variation within the C57BL/6J inbred mouse strain. Genome Res (2007) 1.71
Organogenesis relies on SoxC transcription factors for the survival of neural and mesenchymal progenitors. Nat Commun (2010) 1.69
Multiple conserved regulatory elements with overlapping functions determine Sox10 expression in mouse embryogenesis. Nucleic Acids Res (2007) 1.68
Brain area-specific effect of TGF-beta signaling on Wnt-dependent neural stem cell expansion. Cell Stem Cell (2008) 1.67
The cell-intrinsic requirement of Sox6 for cortical interneuron development. Neuron (2009) 1.66
Transcription factors Sox8 and Sox10 perform non-equivalent roles during oligodendrocyte development despite functional redundancy. Development (2004) 1.66
The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors. Nucleic Acids Res (2006) 1.64
Spotlight on spotted mice: a review of white spotting mouse mutants and associated human pigmentation disorders. Pigment Cell Res (2004) 1.63
Identification of neural crest and glial enhancers at the mouse Sox10 locus through transgenesis in zebrafish. PLoS Genet (2008) 1.60
Loss of DNA-dependent dimerization of the transcription factor SOX9 as a cause for campomelic dysplasia. Hum Mol Genet (2003) 1.59
Identification of Sox8 as a modifier gene in a mouse model of Hirschsprung disease reveals underlying molecular defect. Dev Biol (2005) 1.57
Induction of oligodendrocyte differentiation by Olig2 and Sox10: evidence for reciprocal interactions and dosage-dependent mechanisms. Dev Biol (2006) 1.55
Mutation of the diamond-blackfan anemia gene Rps7 in mouse results in morphological and neuroanatomical phenotypes. PLoS Genet (2013) 1.50
Inactivation of TGFbeta signaling in neural crest stem cells leads to multiple defects reminiscent of DiGeorge syndrome. Genes Dev (2005) 1.50
Prolonged glial expression of Sox4 in the CNS leads to architectural cerebellar defects and ataxia. J Neurosci (2007) 1.50
Sox10 is required for Schwann cell identity and progression beyond the immature Schwann cell stage. J Cell Biol (2010) 1.48
Sox10 promotes the formation and maintenance of giant congenital naevi and melanoma. Nat Cell Biol (2012) 1.48
Sox10 haploinsufficiency affects maintenance of progenitor cells in a mouse model of Hirschsprung disease. Hum Mol Genet (2002) 1.45
NRG1 / ERBB3 signaling in melanocyte development and melanoma: inhibition of differentiation and promotion of proliferation. Pigment Cell Melanoma Res (2009) 1.45
MYRF is a membrane-associated transcription factor that autoproteolytically cleaves to directly activate myelin genes. PLoS Biol (2013) 1.45
Sox9 and Sox10 influence survival and migration of oligodendrocyte precursors in the spinal cord by regulating PDGF receptor alpha expression. Development (2008) 1.45
Neural crest stem cell maintenance by combinatorial Wnt and BMP signaling. J Cell Biol (2005) 1.44
Expression of Sox transcription factors in the developing mouse pancreas. Dev Dyn (2003) 1.43
Development of the Schwann cell lineage: from the neural crest to the myelinated nerve. Glia (2008) 1.42
Wnt signaling and the regulation of stem cell function. Curr Opin Cell Biol (2004) 1.42
Transcriptional and signaling regulation in neural crest stem cell-derived melanocyte development: do all roads lead to Mitf? Cell Res (2008) 1.42
Melanocytes don't always take the high road. Pigment Cell Melanoma Res (2009) 1.39
SoxE function in vertebrate nervous system development. Int J Biochem Cell Biol (2009) 1.38
Sox proteins in melanocyte development and melanoma. Pigment Cell Melanoma Res (2010) 1.38
The importance of having your SOX on: role of SOX10 in the development of neural crest-derived melanocytes and glia. Oncogene (2003) 1.37
Neural crest origin of perivascular mesenchyme in the adult thymus. J Immunol (2008) 1.36
Sox12 deletion in the mouse reveals nonreciprocal redundancy with the related Sox4 and Sox11 transcription factors. Mol Cell Biol (2008) 1.35
Integration of ChIP-seq and machine learning reveals enhancers and a predictive regulatory sequence vocabulary in melanocytes. Genome Res (2012) 1.35
The secreted metalloprotease ADAMTS20 is required for melanoblast survival. PLoS Genet (2008) 1.34
Efficient isolation and gene expression profiling of small numbers of neural crest stem cells and developing Schwann cells. J Neurosci (2004) 1.33
Testis cord differentiation after the sex determination stage is independent of Sox9 but fails in the combined absence of Sox9 and Sox8. Dev Biol (2008) 1.31
An evolutionarily conserved intronic region controls the spatiotemporal expression of the transcription factor Sox10. BMC Dev Biol (2008) 1.31
Establishment and controlled differentiation of neural crest stem cell lines using conditional transgenesis. Differentiation (2007) 1.30
Sox10 is an active nucleocytoplasmic shuttle protein, and shuttling is crucial for Sox10-mediated transactivation. Mol Cell Biol (2002) 1.30
Neural crest progenitors and stem cells: from early development to adulthood. Dev Biol (2012) 1.29
The transcription factor encyclopedia. Genome Biol (2012) 1.28
Cranial neural crest cells regulate head muscle patterning and differentiation during vertebrate embryogenesis. Development (2007) 1.27
Deletion of long-range sequences at Sox10 compromises developmental expression in a mouse model of Waardenburg-Shah (WS4) syndrome. Hum Mol Genet (2005) 1.25
Stage-specific control of neural crest stem cell proliferation by the small rho GTPases Cdc42 and Rac1. Cell Stem Cell (2009) 1.25
Prolonged Sox4 expression in oligodendrocytes interferes with normal myelination in the central nervous system. Mol Cell Biol (2007) 1.24
δ-Tocopherol reduces lipid accumulation in Niemann-Pick type C1 and Wolman cholesterol storage disorders. J Biol Chem (2012) 1.23
Sequential requirement of Sox4 and Sox11 during development of the sympathetic nervous system. Development (2010) 1.22
Temporal control of neural crest lineage generation by Wnt/β-catenin signaling. Development (2012) 1.22
Melanocyte-specific expression of dopachrome tautomerase is dependent on synergistic gene activation by the Sox10 and Mitf transcription factors. FEBS Lett (2004) 1.21
Wnt/BMP signal integration regulates the balance between proliferation and differentiation of neuroepithelial cells in the dorsal spinal cord. Dev Biol (2006) 1.21
Hypomorphic Sox10 alleles reveal novel protein functions and unravel developmental differences in glial lineages. Development (2007) 1.20
Versican V0 and V1 guide migratory neural crest cells. J Biol Chem (2006) 1.19
The high mobility group transcription factor Sox8 is a negative regulator of osteoblast differentiation. J Cell Biol (2005) 1.19
Structure of the GCM domain-DNA complex: a DNA-binding domain with a novel fold and mode of target site recognition. EMBO J (2003) 1.19
Collaborative development of 2-hydroxypropyl-β-cyclodextrin for the treatment of Niemann-Pick type C1 disease. Curr Top Med Chem (2014) 1.19
Oxidative stress in Niemann-Pick disease, type C. Mol Genet Metab (2010) 1.18
Probing transcription-specific outputs of β-catenin in vivo. Genes Dev (2011) 1.18
Chromatin-remodeling factor Brg1 is required for Schwann cell differentiation and myelination. Dev Cell (2012) 1.17
The transcription factor Sox5 modulates Sox10 function during melanocyte development. Nucleic Acids Res (2008) 1.16
A HCN4+ cardiomyogenic progenitor derived from the first heart field and human pluripotent stem cells. Nat Cell Biol (2013) 1.16
Regulation of Sox9 by Sonic Hedgehog (Shh) is essential for patterning and formation of tracheal cartilage. Dev Dyn (2010) 1.16
A sensitized mutagenesis screen identifies Gli3 as a modifier of Sox10 neurocristopathy. Hum Mol Genet (2008) 1.16
Functional sphere profiling reveals the complexity of neuroblastoma tumor-initiating cell model. Neoplasia (2011) 1.15
Olig2 regulates Sox10 expression in oligodendrocyte precursors through an evolutionary conserved distal enhancer. Nucleic Acids Res (2010) 1.15
Pmel17 expression is Mitf-dependent and reveals cranial melanoblast migration during murine development. Gene Expr Patterns (2003) 1.14
Direct interaction of Sox10 with the promoter of murine Dopachrome Tautomerase (Dct) and synergistic activation of Dct expression with Mitf. Pigment Cell Res (2004) 1.14
Neuronal Nogo-A regulates neurite fasciculation, branching and extension in the developing nervous system. Development (2010) 1.13
SOX9 controls epithelial branching by activating RET effector genes during kidney development. Hum Mol Genet (2011) 1.13
The protooncogene Ski controls Schwann cell proliferation and myelination. Neuron (2004) 1.13
Sox8 is a specific marker for muscle satellite cells and inhibits myogenesis. J Biol Chem (2003) 1.12
Replacement of the Sox10 transcription factor by Sox8 reveals incomplete functional equivalence. Development (2006) 1.11
Microarray expression analysis and identification of serum biomarkers for Niemann-Pick disease, type C1. Hum Mol Genet (2012) 1.10
Mutations in TRIOBP, which encodes a putative cytoskeletal-organizing protein, are associated with nonsyndromic recessive deafness. Am J Hum Genet (2005) 1.10
Membrane-bound neuregulin1 type III actively promotes Schwann cell differentiation of multipotent Progenitor cells. Dev Biol (2002) 1.10
Sox10 is required for Schwann-cell homeostasis and myelin maintenance in the adult peripheral nerve. Glia (2011) 1.09
Sox10-rtTA mouse line for tetracycline-inducible expression of transgenes in neural crest cells and oligodendrocytes. Genesis (2004) 1.09