Published in J Biol Chem on November 11, 2002
The last CTD repeat of the mammalian RNA polymerase II large subunit is important for its stability. Nucleic Acids Res (2004) 1.23
Comparative genomics of cyclin-dependent kinases suggest co-evolution of the RNAP II C-terminal domain and CTD-directed CDKs. BMC Genomics (2004) 1.22
Interaction of cyclin-dependent kinase 12/CrkRS with cyclin K1 is required for the phosphorylation of the C-terminal domain of RNA polymerase II. Mol Cell Biol (2012) 1.08
Orphan kinases turn eccentric: a new class of cyclin Y-activated, membrane-targeted CDKs. Cell Cycle (2012) 1.04
Failure to proliferate and mitotic arrest of CDK11(p110/p58)-null mutant mice at the blastocyst stage of embryonic cell development. Mol Cell Biol (2004) 1.01
Cyclin-dependent kinase inhibitor drugs as potential novel anti-inflammatory and pro-resolution agents. Br J Pharmacol (2009) 1.00
Drosophila MCRS2 associates with RNA polymerase II complexes to regulate transcription. Mol Cell Biol (2010) 0.94
Activation of pre-mRNA splicing by human RNPS1 is regulated by CK2 phosphorylation. Mol Cell Biol (2005) 0.93
Regulation of stability of cyclin-dependent kinase CDK11p110 and a caspase-processed form, CDK11p46, by Hsp90. Biochem J (2004) 0.87
Preclinical evaluation of cyclin dependent kinase 11 and casein kinase 2 survival kinases as RNA interference targets for triple negative breast cancer therapy. Breast Cancer Res (2015) 0.87
Molecular mechanisms of HIV latency. J Clin Invest (2016) 0.85
Deregulations in the cyclin-dependent kinase-9-related pathway in cancer: implications for drug discovery and development. ISRN Oncol (2013) 0.84
Cyclin-dependent kinase 11(p110) (CDK11(p110)) is crucial for human breast cancer cell proliferation and growth. Sci Rep (2015) 0.81
Death-signal-induced relocalization of cyclin-dependent kinase 11 to mitochondria. Biochem J (2005) 0.80
The emerging roles and therapeutic potential of cyclin-dependent kinase 11 (CDK11) in human cancer. Oncotarget (2016) 0.79
CDK11 in TREX/THOC Regulates HIV mRNA 3' End Processing. Cell Host Microbe (2015) 0.78
Protein kinase CK2 holoenzyme promotes start-specific transcription in Saccharomyces cerevisiae. Eukaryot Cell (2013) 0.76
Cyclin-Dependent Kinase CRK9, Required for Spliced Leader trans Splicing of Pre-mRNA in Trypanosomes, Functions in a Complex with a New L-Type Cyclin and a Kinetoplastid-Specific Protein. PLoS Pathog (2016) 0.76
Potentiation of neuroblastoma metastasis by loss of caspase-8. Nature (2006) 2.12
ERK activation mediates cell cycle arrest and apoptosis after DNA damage independently of p53. J Biol Chem (2002) 2.03
Differential roles of the COOH termini of AAA subunits of PA700 (19 S regulator) in asymmetric assembly and activation of the 26 S proteasome. J Biol Chem (2008) 1.93
Identification of a multifunctional binding site on Ubc9p required for Smt3p conjugation. J Biol Chem (2002) 1.84
Cyclin-dependent kinases: a family portrait. Nat Cell Biol (2009) 1.80
Phosphorylation of FADD at serine 194 by CKIalpha regulates its nonapoptotic activities. Mol Cell (2005) 1.45
The DNA helicase ChlR1 is required for sister chromatid cohesion in mammalian cells. J Cell Sci (2006) 1.42
Caspase-8 promotes cell motility and calpain activity under nonapoptotic conditions. Cancer Res (2006) 1.37
ASAP, a novel protein complex involved in RNA processing and apoptosis. Mol Cell Biol (2003) 1.34
CDK11 complexes promote pre-mRNA splicing. J Biol Chem (2002) 1.33
Role of CDK/cyclin complexes in transcription and RNA splicing. Cell Signal (2005) 1.32
Caspase-8 association with the focal adhesion complex promotes tumor cell migration and metastasis. Cancer Res (2009) 1.30
Synthetic mRNA splicing modulator compounds with in vivo antitumor activity. J Med Chem (2009) 1.28
Loss of ChlR1 helicase in mouse causes lethality due to the accumulation of aneuploid cells generated by cohesion defects and placental malformation. Cell Cycle (2007) 1.25
Characterization of cyclin L1 and L2 interactions with CDK11 and splicing factors: influence of cyclin L isoforms on splice site selection. J Biol Chem (2008) 1.24
Retinoic acid induces caspase-8 transcription via phospho-CREB and increases apoptotic responses to death stimuli in neuroblastoma cells. Biochim Biophys Acta (2008) 1.21
CDK11(p58) is required for the maintenance of sister chromatid cohesion. J Cell Sci (2007) 1.20
PITSLRE p110 protein kinases associate with transcription complexes and affect their activity. J Biol Chem (2001) 1.16
Apoptotic release of histones from nucleosomes. J Biol Chem (2002) 1.14
A novel CRM1-mediated nuclear export signal governs nuclear accumulation of glyceraldehyde-3-phosphate dehydrogenase following genotoxic stress. J Biol Chem (2003) 1.13
Proteomic studies of the intrinsically unstructured mammalian proteome. J Proteome Res (2006) 1.11
Preclinical models for neuroblastoma: establishing a baseline for treatment. PLoS One (2011) 1.09
A20-binding inhibitor of NF-κB (ABIN1) controls Toll-like receptor-mediated CCAAT/enhancer-binding protein β activation and protects from inflammatory disease. Proc Natl Acad Sci U S A (2011) 1.08
Large-scale analysis of thermostable, mammalian proteins provides insights into the intrinsically disordered proteome. J Proteome Res (2009) 1.02
Failure to proliferate and mitotic arrest of CDK11(p110/p58)-null mutant mice at the blastocyst stage of embryonic cell development. Mol Cell Biol (2004) 1.01
The connections between neural crest development and neuroblastoma. Curr Top Dev Biol (2011) 1.01
Chromosome damage and repair in children with sickle cell anaemia and long-term hydroxycarbamide exposure. Br J Haematol (2011) 0.99
Evaluation of IFN-gamma effects on apoptosis and gene expression in neuroblastoma--preclinical studies. Biochim Biophys Acta (2006) 0.98
Three-dimensional structure of an immunoglobulin light-chain dimer with amyloidogenic properties. Acta Crystallogr D Biol Crystallogr (2002) 0.94
Cyclin dependent kinase 11 in RNA transcription and splicing. Prog Nucleic Acid Res Mol Biol (2004) 0.93
Phase I study of decitabine with doxorubicin and cyclophosphamide in children with neuroblastoma and other solid tumors: a Children's Oncology Group study. Pediatr Blood Cancer (2010) 0.93
Activation of pre-mRNA splicing by human RNPS1 is regulated by CK2 phosphorylation. Mol Cell Biol (2005) 0.93
Binding of JNK/SAPK to MEKK1 is regulated by phosphorylation. J Biol Chem (2002) 0.93
Perturbation of HP1 localization and chromatin binding ability causes defects in sister-chromatid cohesion. Mutat Res (2008) 0.90
The microenvironmental determinants for kidney epithelial cyst morphogenesis. Eur J Cell Biol (2008) 0.89
Th-MYCN mice with caspase-8 deficiency develop advanced neuroblastoma with bone marrow metastasis. Cancer Res (2013) 0.88
Tetraspanin CD151 maintains vascular stability by balancing the forces of cell adhesion and cytoskeletal tension. Blood (2011) 0.87
Prevalence of necrosis in C2-ceramide-induced cytotoxicity in NB16 neuroblastoma cells. Mol Pharmacol (2003) 0.87
Crystal structure of a glycosylated Fab from an IgM cryoglobulin with properties of a natural proteolytic antibody. Biochem J (2006) 0.87
Caspase-9 and Apaf-1 are expressed and functionally active in human neuroblastoma tumor cell lines with 1p36 LOH and amplified MYCN. Oncogene (2002) 0.86
Mammalian ChlR1 has a role in heterochromatin organization. Exp Cell Res (2011) 0.84
Roles of ChlR1 DNA helicase in replication recovery from DNA damage. Exp Cell Res (2013) 0.81
Bub1-mediated adaptation of the spindle checkpoint. PLoS Genet (2011) 0.81
Halting neuroblastoma metastasis by controlling integrin-mediated death. Cell Cycle (2006) 0.79
Tetraspanin CD82 inhibits protrusion and retraction in cell movement by attenuating the plasma membrane-dependent actin organization. PLoS One (2012) 0.79
The carboxyl-terminus directs TAF(I)48 to the nucleus and nucleolus and associates with multiple nuclear import receptors. J Biochem (2004) 0.78
The influence of phosphorylation on the activity and structure of the neuronal IQ motif protein, PEP-19. Brain Res (2006) 0.78
The RNA binding motif protein 15B (RBM15B/OTT3) is a functional competitor of serine-arginine (SR) proteins and antagonizes the positive effect of the CDK11p110-cyclin L2α complex on splicing. J Biol Chem (2010) 0.78
Two isoforms of the human cyclin C gene are expressed differentially suggesting that they may have distinct functions. Acta Biol Hung (2007) 0.77
The murine G+C-rich promoter binding protein mGPBP is required for promoter-specific transcription. Mol Cell Biol (2003) 0.77
MDR1 C2005T polymorphism changes substrate specificity. Cancer Chemother Pharmacol (2010) 0.76
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