Published in Oncogene on November 28, 2002
The transcriptional and epigenomic foundations of ground state pluripotency. Cell (2012) 5.87
Embryonic stem cell-specific microRNAs regulate the G1-S transition and promote rapid proliferation. Nat Genet (2008) 5.26
Droplet barcoding for single-cell transcriptomics applied to embryonic stem cells. Cell (2015) 4.42
Rb regulates interactions between hematopoietic stem cells and their bone marrow microenvironment. Cell (2007) 3.82
The cell cycle and Myc intersect with mechanisms that regulate pluripotency and reprogramming. Cell Stem Cell (2009) 2.72
Cyclins E1 and E2 are required for endoreplication in placental trophoblast giant cells. EMBO J (2003) 2.34
Genome-wide mapping and analysis of active promoters in mouse embryonic stem cells and adult organs. Genome Res (2007) 2.16
Developmental activation of the Rb-E2F pathway and establishment of cell cycle-regulated cyclin-dependent kinase activity during embryonic stem cell differentiation. Mol Biol Cell (2005) 2.00
Restoration of an absent G1 arrest and protection from apoptosis in embryonic stem cells after ionizing radiation. Proc Natl Acad Sci U S A (2004) 1.96
Myc represses primitive endoderm differentiation in pluripotent stem cells. Cell Stem Cell (2010) 1.90
Diet controls normal and tumorous germline stem cells via insulin-dependent and -independent mechanisms in Drosophila. Dev Biol (2007) 1.74
Cell cycle regulation by MicroRNAs in embryonic stem cells. Cancer Res (2009) 1.69
Cell cycle features of primate embryonic stem cells. Stem Cells (2005) 1.64
p53 regulates cell cycle and microRNAs to promote differentiation of human embryonic stem cells. PLoS Biol (2012) 1.63
Mitotic and mitogenic Wnt signalling. EMBO J (2012) 1.62
p53, Stem Cells, and Reprogramming: Tumor Suppression beyond Guarding the Genome. Genes Cancer (2011) 1.54
Geminin is essential to prevent endoreduplication and to form pluripotent cells during mammalian development. Genes Dev (2006) 1.49
G1 to S phase cell cycle transition in somatic and embryonic stem cells. J Anat (2008) 1.48
The cyclin-dependent kinase inhibitor p21 is a crucial target for histone deacetylase 1 as a regulator of cellular proliferation. Mol Cell Biol (2009) 1.42
Arabidopsis RETINOBLASTOMA-RELATED is required for stem cell maintenance, cell differentiation, and lateral organ production. Plant Cell (2010) 1.39
Cyclin E and CDK-2 regulate proliferative cell fate and cell cycle progression in the C. elegans germline. Development (2011) 1.31
Histone H2a mRNA interacts with Lin28 and contains a Lin28-dependent posttranscriptional regulatory element. Nucleic Acids Res (2009) 1.31
Subcellular localization of glycogen synthase kinase 3beta controls embryonic stem cell self-renewal. Mol Cell Biol (2009) 1.31
MicroRNAs in embryonic stem cell function and fate. Genes Dev (2010) 1.27
Quality control: Genome maintenance in pluripotent stem cells. J Cell Biol (2014) 1.27
Evolutionarily conserved transcriptional co-expression guiding embryonic stem cell differentiation. PLoS One (2008) 1.24
Geminin escapes degradation in G1 of mouse pluripotent cells and mediates the expression of Oct4, Sox2, and Nanog. Curr Biol (2011) 1.24
Rem2 GTPase maintains survival of human embryonic stem cells as well as enhancing reprogramming by regulating p53 and cyclin D1. Genes Dev (2010) 1.23
In search of "stemness". Exp Hematol (2004) 1.21
The FunGenES database: a genomics resource for mouse embryonic stem cell differentiation. PLoS One (2009) 1.15
Gap 1 phase length and mouse embryonic stem cell self-renewal. Proc Natl Acad Sci U S A (2012) 1.15
IDAWG: Metabolic incorporation of stable isotope labels for quantitative glycomics of cultured cells. J Proteome Res (2009) 1.15
DNA synthesis is required for reprogramming mediated by stem cell fusion. Cell (2013) 1.14
Regulation of mouse embryonic stem cell neural differentiation by retinoic acid. Dev Biol (2009) 1.14
Stem cell pluripotency: a cellular trait that depends on transcription factors, chromatin state and a checkpoint deficient cell cycle. J Cell Physiol (2009) 1.13
Cell cycle adaptations of embryonic stem cells. Proc Natl Acad Sci U S A (2011) 1.11
The abbreviated pluripotent cell cycle. J Cell Physiol (2013) 1.09
Nucleostemin maintains self-renewal of embryonic stem cells and promotes reprogramming of somatic cells to pluripotency. J Cell Biol (2012) 1.08
CDK1 inhibition targets the p53-NOXA-MCL1 axis, selectively kills embryonic stem cells, and prevents teratoma formation. Stem Cell Reports (2015) 1.08
The cell cycle and pluripotency. Biochem J (2013) 1.03
microRNA control of mouse and human pluripotent stem cell behavior. Annu Rev Cell Dev Biol (2013) 1.02
Keeping an eye on retinoblastoma control of human embryonic stem cells. J Cell Biochem (2009) 1.01
Myc transcription factors: key regulators behind establishment and maintenance of pluripotency. Regen Med (2010) 1.00
Cyclin A/cdk2 regulates adenomatous polyposis coli-dependent mitotic spindle anchoring. J Biol Chem (2009) 1.00
Sin3a is essential for the genome integrity and viability of pluripotent cells. Dev Biol (2011) 1.00
Alterations of proliferative and differentiation potentials of human embryonic stem cells during long-term culture. Exp Mol Med (2008) 1.00
Tandem E2F binding sites in the promoter of the p107 cell cycle regulator control p107 expression and its cellular functions. PLoS Genet (2010) 0.99
miR-294/miR-302 promotes proliferation, suppresses G1-S restriction point, and inhibits ESC differentiation through separable mechanisms. Cell Rep (2013) 0.99
RNA interference and retinoblastoma-related genes are required for repression of endogenous siRNA targets in Caenorhabditis elegans. Proc Natl Acad Sci U S A (2008) 0.98
Erk signaling is indispensable for genomic stability and self-renewal of mouse embryonic stem cells. Proc Natl Acad Sci U S A (2015) 0.97
FBF represses the Cip/Kip cell-cycle inhibitor CKI-2 to promote self-renewal of germline stem cells in C. elegans. EMBO J (2011) 0.97
Antiviral responses in mouse embryonic stem cells: differential development of cellular mechanisms in type I interferon production and response. J Biol Chem (2014) 0.96
Mouse embryonic stem cells are deficient in type I interferon expression in response to viral infections and double-stranded RNA. J Biol Chem (2013) 0.95
Glycoproteomic analysis of embryonic stem cells: identification of potential glycobiomarkers using lectin affinity chromatography of glycopeptides. J Proteome Res (2010) 0.93
Rb and hematopoiesis: stem cells to anemia. Cell Div (2008) 0.93
Coordinating cell proliferation and differentiation: Antagonism between cell cycle regulators and cell type-specific gene expression. Cell Cycle (2016) 0.93
Transcriptional repression by the BRG1-SWI/SNF complex affects the pluripotency of human embryonic stem cells. Stem Cell Reports (2014) 0.92
Screening of human pluripotent stem cells using CGH and FISH reveals low-grade mosaic aneuploidy and a recurrent amplification of chromosome 1q. Eur J Hum Genet (2012) 0.92
DNA damage mediated s and g(2) checkpoints in human embryonal carcinoma cells. Stem Cells (2009) 0.89
The B-MYB transcriptional network guides cell cycle progression and fate decisions to sustain self-renewal and the identity of pluripotent stem cells. PLoS One (2012) 0.88
Exposing hidden dimensions of embryonic stem cell cycle control. Cell Stem Cell (2009) 0.87
Cyclin D2 and the CDK substrate p220(NPAT) are required for self-renewal of human embryonic stem cells. J Cell Physiol (2010) 0.87
Modulation of cell cycle control during oocyte-to-embryo transitions. EMBO J (2013) 0.87
Concise Review: Control of Cell Fate Through Cell Cycle and Pluripotency Networks. Stem Cells (2016) 0.86
Integrative framework for identification of key cell identity genes uncovers determinants of ES cell identity and homeostasis. Proc Natl Acad Sci U S A (2014) 0.86
Multilayered chromatin analysis reveals E2f, Smad and Zfx as transcriptional regulators of histones. Nat Struct Mol Biol (2012) 0.86
MicroRNAs and Cardiac Regeneration. Circ Res (2015) 0.86
Induced pluripotent stem cells: emerging techniques for nuclear reprogramming. Antioxid Redox Signal (2011) 0.85
How microRNAs facilitate reprogramming to pluripotency. J Cell Sci (2012) 0.85
Initiation and termination of DNA replication during S phase in relation to cyclins D1, E and A, p21WAF1, Cdt1 and the p12 subunit of DNA polymerase δ revealed in individual cells by cytometry. Oncotarget (2015) 0.85
Cell cycle regulation of embryonic stem cells and mouse embryonic fibroblasts lacking functional Pax7. Cell Cycle (2016) 0.85
Linking the Cell Cycle to Cell Fate Decisions. Trends Cell Biol (2015) 0.85
Cycling through developmental decisions: how cell cycle dynamics control pluripotency, differentiation and reprogramming. Development (2016) 0.84
The abundance of Rad51 protein in mouse embryonic stem cells is regulated at multiple levels. Stem Cell Res (2012) 0.84
Mitotic binding of Esrrb marks key regulatory regions of the pluripotency network. Nat Cell Biol (2016) 0.84
Embryonic stem cell miRNAs and their roles in development and disease. Semin Cancer Biol (2012) 0.84
Integrative genomics positions MKRN1 as a novel ribonucleoprotein within the embryonic stem cell gene regulatory network. EMBO Rep (2015) 0.84
Nonmitogenic survival-enhancing autocrine factors including cyclophilin A contribute to density-dependent mouse embryonic stem cell growth. Stem Cell Res (2010) 0.83
Functional analysis of the Cdk7.cyclin H.Mat1 complex in mouse embryonic stem cells and embryos. J Biol Chem (2010) 0.83
Ethanol alters the balance of Sox2, Oct4, and Nanog expression in distinct subpopulations during differentiation of embryonic stem cells. Stem Cells Dev (2013) 0.83
Retinoic acid-treated pluripotent stem cells undergoing neurogenesis present increased aneuploidy and micronuclei formation. PLoS One (2011) 0.83
A nontranscriptional role for Oct4 in the regulation of mitotic entry. Proc Natl Acad Sci U S A (2014) 0.82
Cyclin-dependent kinase 2-associating protein 1 commits murine embryonic stem cell differentiation through retinoblastoma protein regulation. J Biol Chem (2009) 0.82
A new coactivator function for Zac1's C2H2 zinc finger DNA-binding domain in selectively controlling PCAF activity. Mol Cell Biol (2008) 0.82
Cell Cycle-Driven Heterogeneity: On the Road to Demystifying the Transitions between "Poised" and "Restricted" Pluripotent Cell States. Stem Cells Int (2015) 0.81
Transient inhibition of cell proliferation does not compromise self-renewal of mouse embryonic stem cells. Exp Cell Res (2012) 0.81
Microfluidics-integrated time-lapse imaging for analysis of cellular dynamics. Integr Biol (Camb) (2010) 0.80
Double edge: CDK2AP1 in cell-cycle regulation and epigenetic regulation. J Dent Res (2011) 0.80
Neural development is dependent on the function of specificity protein 2 in cell cycle progression. Development (2013) 0.80
Toward the beginning of time: circadian rhythms in metabolism precede rhythms in clock gene expression in mouse embryonic stem cells. PLoS One (2012) 0.79
An opposite effect of the CDK inhibitor, p18(INK4c) on embryonic stem cells compared with tumor and adult stem cells. PLoS One (2012) 0.79
A protocol to assess cell cycle and apoptosis in human and mouse pluripotent cells. Cell Commun Signal (2011) 0.79
Distinct activities of the anaphase-promoting complex/cyclosome (APC/C) in mouse embryonic cells. Cell Cycle (2012) 0.79
Aging of the inceptive cellular population: the relationship between stem cells and aging. Aging (Albany NY) (2009) 0.79
Effects of hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers on the proliferation and cell cycle progression of embryonic stem cells. Pflugers Arch (2010) 0.79
Life without geminin. Cell Cycle (2010) 0.79
Micro-management of pluripotent stem cells. Protein Cell (2014) 0.78
Normal development in mice over-expressing the intracellular domain of DLL1 argues against reverse signaling by DLL1 in vivo. PLoS One (2013) 0.78
Geminin promotes an epithelial-to-mesenchymal transition in an embryonic stem cell model of gastrulation. Stem Cells Dev (2013) 0.78
ASPM regulates symmetric stem cell division by tuning Cyclin E ubiquitination. Nat Commun (2015) 0.78
Follicular lymphoma international prognostic index. Blood (2004) 7.20
Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cells. Hepatology (2010) 6.40
Architectural protein subclasses shape 3D organization of genomes during lineage commitment. Cell (2013) 6.37
LIF/STAT3 controls ES cell self-renewal and pluripotency by a Myc-dependent mechanism. Development (2005) 5.80
Evolutionarily conserved replication timing profiles predict long-range chromatin interactions and distinguish closely related cell types. Genome Res (2010) 4.67
Genome-wide dynamics of replication timing revealed by in vitro models of mouse embryogenesis. Genome Res (2009) 3.36
Activin a efficiently specifies definitive endoderm from human embryonic stem cells only when phosphatidylinositol 3-kinase signaling is suppressed. Stem Cells (2007) 3.04
Preserving the genetic integrity of human embryonic stem cells. Nat Biotechnol (2005) 3.03
The cell cycle and Myc intersect with mechanisms that regulate pluripotency and reprogramming. Cell Stem Cell (2009) 2.72
Cell cycle control of embryonic stem cells. Stem Cell Rev (2005) 2.64
Palliative models of care for later stages of mental disorder: maximizing recovery, maintaining hope, and building morale. Aust N Z J Psychiatry (2012) 2.02
Developmental activation of the Rb-E2F pathway and establishment of cell cycle-regulated cyclin-dependent kinase activity during embryonic stem cell differentiation. Mol Biol Cell (2005) 2.00
Signaling network crosstalk in human pluripotent cells: a Smad2/3-regulated switch that controls the balance between self-renewal and differentiation. Cell Stem Cell (2012) 1.94
Myc represses primitive endoderm differentiation in pluripotent stem cells. Cell Stem Cell (2010) 1.90
Clinical staging: a heuristic and practical strategy for new research and better health and social outcomes for psychotic and related mood disorders. Can J Psychiatry (2010) 1.64
L-Proline induces differentiation of ES cells: a novel role for an amino acid in the regulation of pluripotent cells in culture. Am J Physiol Cell Physiol (2010) 1.64
Wnt signaling and a Smad pathway blockade direct the differentiation of human pluripotent stem cells to multipotent neural crest cells. Proc Natl Acad Sci U S A (2011) 1.56
Age of onset and timing of treatment for mental and substance use disorders: implications for preventive intervention strategies and models of care. Curr Opin Psychiatry (2011) 1.54
Glycomics of proteoglycan biosynthesis in murine embryonic stem cell differentiation. J Proteome Res (2007) 1.46
Recruitment of Thr 319-phosphorylated Ndd1p to the FHA domain of Fkh2p requires Clb kinase activity: a mechanism for CLB cluster gene activation. Genes Dev (2003) 1.45
Cdk6-cyclin D3 activity in murine ES cells is resistant to inhibition by p16(INK4a). Oncogene (2004) 1.35
Subcellular localization of glycogen synthase kinase 3beta controls embryonic stem cell self-renewal. Mol Cell Biol (2009) 1.31
Productive hepatitis C virus infection of stem cell-derived hepatocytes reveals a critical transition to viral permissiveness during differentiation. PLoS Pathog (2012) 1.29
Linking DNA methyltransferases to epigenetic marks and nucleosome structure genome-wide in human tumor cells. Cell Rep (2012) 1.27
Biomarkers and clinical staging in psychiatry. World Psychiatry (2014) 1.22
Replication timing: a fingerprint for cell identity and pluripotency. PLoS Comput Biol (2011) 1.21
Human motor neuron differentiation from human embryonic stem cells. Stem Cells Dev (2005) 1.15
IDAWG: Metabolic incorporation of stable isotope labels for quantitative glycomics of cultured cells. J Proteome Res (2009) 1.15
Sister kinetochore recapture in fission yeast occurs by two distinct mechanisms, both requiring Dam1 and Klp2. Mol Biol Cell (2008) 1.13
SNS-032 is a potent and selective CDK 2, 7 and 9 inhibitor that drives target modulation in patient samples. Cancer Chemother Pharmacol (2009) 1.08
Roles for MYC in the establishment and maintenance of pluripotency. Cold Spring Harb Perspect Med (2013) 1.06
Directed differentiation of human pluripotent cells to neural crest stem cells. Nat Protoc (2013) 1.04
MYC/MAX control ERK signaling and pluripotency by regulation of dual-specificity phosphatases 2 and 7. Genes Dev (2013) 1.04
Heparan sulfate facilitates FGF and BMP signaling to drive mesoderm differentiation of mouse embryonic stem cells. J Biol Chem (2012) 1.03
A chromosome-centric human proteome project (C-HPP) to characterize the sets of proteins encoded in chromosome 17. J Proteome Res (2012) 1.03
ARRY-520, a novel KSP inhibitor with potent activity in hematological and taxane-resistant tumor models. Anticancer Res (2009) 1.01
Myc transcription factors: key regulators behind establishment and maintenance of pluripotency. Regen Med (2010) 1.00
Xylem ionic relations and salinity tolerance in barley. Plant J (2009) 0.97
Regulation of glycan structures in murine embryonic stem cells: combined transcript profiling of glycan-related genes and glycan structural analysis. J Biol Chem (2012) 0.97
The response of the maize nitrate transport system to nitrogen demand and supply across the lifecycle. New Phytol (2013) 0.97
Myc orchestrates a regulatory network required for the establishment and maintenance of pluripotency. Cell Cycle (2011) 0.94
Glycoproteomic analysis of embryonic stem cells: identification of potential glycobiomarkers using lectin affinity chromatography of glycopeptides. J Proteome Res (2010) 0.93
Transcriptional profiling of initial differentiation events in human embryonic stem cells. Biochem Biophys Res Commun (2004) 0.93
Transcriptional control of pluripotency: decisions in early development. Curr Opin Genet Dev (2006) 0.93
Frat is a phosphatidylinositol 3-kinase/Akt-regulated determinant of glycogen synthase kinase 3β subcellular localization in pluripotent cells. Mol Cell Biol (2011) 0.91
The lectin Dolichos biflorus agglutinin recognizes glycan epitopes on the surface of murine embryonic stem cells: a new tool for characterizing pluripotent cells and early differentiation. Stem Cells (2006) 0.91
Transcript profiling and lipidomic analysis of ceramide subspecies in mouse embryonic stem cells and embryoid bodies. J Lipid Res (2009) 0.89
Dynein participates in chromosome segregation in fission yeast. Biol Cell (2007) 0.89
Differentiation of embryonic stem cells to a neural fate: a route to re-building the nervous system? J Neurosci Res (2004) 0.88
Embryonic stem cell differentiation and the analysis of mammalian development. Int J Dev Biol (2002) 0.88
The validity and heritability of self-report osteoarthritis in an Australian older twin sample. Twin Res (2002) 0.87
Heparan sulfate: a key regulator of embryonic stem cell fate. Biol Chem (2013) 0.86
Transcriptional profiling of definitive endoderm derived from human embryonic stem cells. Comput Syst Bioinformatics Conf (2007) 0.86
Efficient generation of alpha(1,3) galactosyltransferase knockout porcine fetal fibroblasts for nuclear transfer. Transgenic Res (2002) 0.85
A comparison of two in vitro maturation media for use with adult porcine oocytes for adult somatic cell nuclear transfer. Cloning Stem Cells (2007) 0.83
Reconciling the different roles of Gsk3β in "naïve" and "primed" pluripotent stem cells. Cell Cycle (2012) 0.83
A novel role for gamma-secretase in the formation of primitive streak-like intermediates from ES cells in culture. Stem Cells (2009) 0.83
An efficient method for producing alpha(1,3)-galactosyltransferase gene knockout pigs. Cloning Stem Cells (2004) 0.82
Response to BMP4 signalling during ES cell differentiation defines intermediates of the ectoderm lineage. J Cell Sci (2010) 0.82
Tetraploid embryonic stem cells contribute to the inner cell mass of mouse blastocysts. Cloning Stem Cells (2005) 0.81
Is this normal? Assessing mental health in young people. Aust Fam Physician (2011) 0.80
Lectin-functionalized microchannels for characterizing pluripotent cells and early differentiation. Biomicrofluidics (2012) 0.80
The amino acid transporter SNAT2 mediates L-proline-induced differentiation of ES cells. Am J Physiol Cell Physiol (2011) 0.79
To Stretch the Boundary of Secondary Metabolite Production in Plant Cell-Based Bioprocessing: Anthocyanin as a Case Study. J Biomed Biotechnol (2004) 0.79
Altered cell cycle regulation helps stem-like carcinoma cells resist apoptosis. BMC Biol (2010) 0.78
The fission yeast spindle orientation checkpoint: a model that generates tension? Yeast (2006) 0.78
Investigating the effectiveness, safety and tolerability of quetiapine in the treatment of anorexia nervosa in young people: a pilot study. J Psychiatr Res (2010) 0.78
Manipulation of cell:cell contacts and mesoderm suppressing activity direct lineage choice from pluripotent primitive ectoderm-like cells in culture. PLoS One (2009) 0.77
A system to enrich for primitive streak-derivatives, definitive endoderm and mesoderm, from pluripotent cells in culture. PLoS One (2012) 0.77
A requirement for FGF signalling in the formation of primitive streak-like intermediates from primitive ectoderm in culture. PLoS One (2010) 0.77
Embryonic stem cell-derived glial precursors as a vehicle for sulfamidase production in the MPS-IIIA mouse brain. Cell Transplant (2010) 0.77
Automated 3D quantitative assessment and measurement of alpha angles from the femoral head-neck junction using MR imaging. Phys Med Biol (2015) 0.76
Commentary on 'Palliative models of care for later stages of mental disorder: maximising recovery, maintaining hope and building morale'. Aust N Z J Psychiatry (2012) 0.75
NHS England chief executive: welcome back, Simon. Here's your to-do list. Health Serv J (2014) 0.75
Improving mental health in young people. Psychiatr Danub (2012) 0.75
Cell-Cycle Control of Developmentally Regulated Transcription Factors Accounts for Heterogeneity in Human Pluripotent Cells. Stem Cell Reports (2014) 0.75