Published in EMBO J on December 02, 2002
Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase. EMBO J (2004) 11.00
SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span. Cell (2009) 6.09
NF-κB, the first quarter-century: remarkable progress and outstanding questions. Genes Dev (2012) 5.77
Signalling through C-type lectin receptors: shaping immune responses. Nat Rev Immunol (2009) 4.98
The NF-kappaB family of transcription factors and its regulation. Cold Spring Harb Perspect Biol (2009) 4.61
Dangerous liaisons: STAT3 and NF-kappaB collaboration and crosstalk in cancer. Cytokine Growth Factor Rev (2009) 4.10
Brd4 coactivates transcriptional activation of NF-kappaB via specific binding to acetylated RelA. Mol Cell Biol (2008) 3.74
Persistently activated Stat3 maintains constitutive NF-kappaB activity in tumors. Cancer Cell (2009) 3.71
Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers. Nat Biotechnol (2015) 3.56
NF-kappaB RelA phosphorylation regulates RelA acetylation. Mol Cell Biol (2005) 3.50
HIV latency. Cold Spring Harb Perspect Med (2011) 2.90
A comprehensive map of the toll-like receptor signaling network. Mol Syst Biol (2006) 2.89
NF-κB addiction and its role in cancer: 'one size does not fit all'. Oncogene (2010) 2.56
Inhibiting NF-κB activation by small molecules as a therapeutic strategy. Biochim Biophys Acta (2010) 2.55
SIRT1, an antiinflammatory and antiaging protein, is decreased in lungs of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2008) 2.49
Regulation of NF-kappaB activity through lysine monomethylation of p65. Proc Natl Acad Sci U S A (2009) 2.10
Regulation of NF-kappaB by NSD1/FBXL11-dependent reversible lysine methylation of p65. Proc Natl Acad Sci U S A (2009) 2.10
IkappaB kinase alpha-mediated derepression of SMRT potentiates acetylation of RelA/p65 by p300. Mol Cell Biol (2006) 2.05
Negative regulation of NF-kappaB action by Set9-mediated lysine methylation of the RelA subunit. EMBO J (2009) 2.05
Overexpression of SIRT1 protects pancreatic beta-cells against cytokine toxicity by suppressing the nuclear factor-kappaB signaling pathway. Diabetes (2008) 2.00
Posttranslational modifications of NF-kappaB: another layer of regulation for NF-kappaB signaling pathway. Cell Signal (2010) 1.99
Myeloid deletion of SIRT1 induces inflammatory signaling in response to environmental stress. Mol Cell Biol (2010) 1.94
Regulation of SIRT1 in cellular functions: role of polyphenols. Arch Biochem Biophys (2010) 1.91
Crosstalk in inflammation: the interplay of glucocorticoid receptor-based mechanisms and kinases and phosphatases. Endocr Rev (2009) 1.88
Acetylation of estrogen receptor alpha by p300 at lysines 266 and 268 enhances the deoxyribonucleic acid binding and transactivation activities of the receptor. Mol Endocrinol (2006) 1.73
Recruitment of TFIIH to the HIV LTR is a rate-limiting step in the emergence of HIV from latency. EMBO J (2006) 1.68
Breast cancer metastasis suppressor 1 functions as a corepressor by enhancing histone deacetylase 1-mediated deacetylation of RelA/p65 and promoting apoptosis. Mol Cell Biol (2006) 1.68
HDAC-mediated deacetylation of NF-κB is critical for Schwann cell myelination. Nat Neurosci (2011) 1.67
Helicobacter pylori CagA activates NF-kappaB by targeting TAK1 for TRAF6-mediated Lys 63 ubiquitination. EMBO Rep (2009) 1.63
GCN5 is a required cofactor for a ubiquitin ligase that targets NF-kappaB/RelA. Genes Dev (2009) 1.62
NF-kappa B-mediated adaptive resistance to ionizing radiation. Free Radic Biol Med (2007) 1.58
Coactivators and corepressors of NF-kappaB in IkappaB alpha gene promoter. J Biol Chem (2005) 1.57
Dual regulation of c-Myc by p300 via acetylation-dependent control of Myc protein turnover and coactivation of Myc-induced transcription. Mol Cell Biol (2005) 1.54
Histone deacetylase inhibitors suppress rheumatoid arthritis fibroblast-like synoviocyte and macrophage IL-6 production by accelerating mRNA decay. Ann Rheum Dis (2011) 1.54
NFkappaB activation is associated with its O-GlcNAcylation state under hyperglycemic conditions. Proc Natl Acad Sci U S A (2008) 1.53
TGF-beta induces p65 acetylation to enhance bacteria-induced NF-kappaB activation. EMBO J (2007) 1.49
Transforming activity of MECT1-MAML2 fusion oncoprotein is mediated by constitutive CREB activation. EMBO J (2005) 1.48
Nonhistone protein acetylation as cancer therapy targets. Expert Rev Anticancer Ther (2010) 1.45
Brd4 maintains constitutively active NF-κB in cancer cells by binding to acetylated RelA. Oncogene (2013) 1.44
Activation of nuclear factor kappaB in colonic mucosa from patients with collagenous and ulcerative colitis. Gut (2005) 1.43
Histone deacetylase inhibitors for treating a spectrum of diseases not related to cancer. Mol Med (2011) 1.41
Endogenous modulators and pharmacological inhibitors of histone deacetylases in cancer therapy. Oncogene (2011) 1.38
Functional interplay between acetylation and methylation of the RelA subunit of NF-kappaB. Mol Cell Biol (2010) 1.36
Ser276 phosphorylation of NF-kB p65 by MSK1 controls SCF expression in inflammation. PLoS One (2009) 1.36
Current concepts on oxidative/carbonyl stress, inflammation and epigenetics in pathogenesis of chronic obstructive pulmonary disease. Toxicol Appl Pharmacol (2011) 1.35
Reactivation of latent HIV by histone deacetylase inhibitors. Trends Microbiol (2013) 1.35
Human immunodeficiency virus type 1 Tat protein inhibits the SIRT1 deacetylase and induces T cell hyperactivation. Cell Host Microbe (2008) 1.35
Functional relevance of novel p300-mediated lysine 314 and 315 acetylation of RelA/p65. Nucleic Acids Res (2008) 1.32
MAPK p38 regulates transcriptional activity of NF-kappaB in primary human astrocytes via acetylation of p65. J Immunol (2007) 1.31
Specification of DNA binding activity of NF-kappaB proteins. Cold Spring Harb Perspect Biol (2009) 1.29
Activation of Sirt1 by resveratrol inhibits TNF-α induced inflammation in fibroblasts. PLoS One (2011) 1.29
Core circadian protein CLOCK is a positive regulator of NF-κB-mediated transcription. Proc Natl Acad Sci U S A (2012) 1.28
Mechanistic insights into the events that lead to synergistic induction of interleukin 6 transcription upon activation of the aryl hydrocarbon receptor and inflammatory signaling. J Biol Chem (2010) 1.27
Deacetylases and NF-kappaB in redox regulation of cigarette smoke-induced lung inflammation: epigenetics in pathogenesis of COPD. Antioxid Redox Signal (2008) 1.26
Nucleolar sequestration of RelA (p65) regulates NF-kappaB-driven transcription and apoptosis. Mol Cell Biol (2005) 1.26
Erk5 activation elicits a vasoprotective endothelial phenotype via induction of Kruppel-like factor 4 (KLF4). J Biol Chem (2010) 1.25
SIRT1 activators suppress inflammatory responses through promotion of p65 deacetylation and inhibition of NF-κB activity. PLoS One (2012) 1.23
Selectivity of the NF-{kappa}B response. Cold Spring Harb Perspect Biol (2009) 1.20
Specification of the NF-kappaB transcriptional response by p65 phosphorylation and TNF-induced nuclear translocation of IKK epsilon. Nucleic Acids Res (2010) 1.20
Stimulation of GCMa transcriptional activity by cyclic AMP/protein kinase A signaling is attributed to CBP-mediated acetylation of GCMa. Mol Cell Biol (2005) 1.18
Histone acetyltransferases are crucial regulators in NF-κB mediated inflammation. Drug Discov Today (2011) 1.18
Redox regulation of SIRT1 in inflammation and cellular senescence. Free Radic Biol Med (2013) 1.17
IKK alpha causes chromatin modification on pro-inflammatory genes by cigarette smoke in mouse lung. Am J Respir Cell Mol Biol (2008) 1.17
α-Synuclein negatively regulates protein kinase Cδ expression to suppress apoptosis in dopaminergic neurons by reducing p300 histone acetyltransferase activity. J Neurosci (2011) 1.16
Human immunodeficiency virus-1 Tat activates NF-κB via physical interaction with IκB-α and p65. Nucleic Acids Res (2011) 1.16
Targeting histone deacetylase activity in rheumatoid arthritis and asthma as prototypes of inflammatory disease: should we keep our HATs on? Arthritis Res Ther (2008) 1.15
Retracted Histone deacetylase inhibitors activate NF-kappaB in human leukemia cells through an ATM/NEMO-related pathway. J Biol Chem (2010) 1.14
Novel changes in NF-{kappa}B activity during progression and regression phases of hyperplasia: role of MEK, ERK, and p38. J Biol Chem (2010) 1.12
Epigenetic repression of matrix metalloproteinases in myofibroblastic hepatic stellate cells through histone deacetylases 4: implication in tissue fibrosis. Am J Pathol (2010) 1.11
SIRT1 as a therapeutic target in inflammaging of the pulmonary disease. Prev Med (2011) 1.10
Targeted disruption of NF-{kappa}B1 (p50) augments cigarette smoke-induced lung inflammation and emphysema in mice: a critical role of p50 in chromatin remodeling. Am J Physiol Lung Cell Mol Physiol (2009) 1.09
Modulation of acetylation: creating a pro-survival and anti-inflammatory phenotype in lethal hemorrhagic and septic shock. J Biomed Biotechnol (2011) 1.09
Analysis of the RelA:CBP/p300 interaction reveals its involvement in NF-κB-driven transcription. PLoS Biol (2013) 1.08
Structural basis and specificity of acetylated transcription factor GATA1 recognition by BET family bromodomain protein Brd3. Mol Cell Biol (2011) 1.08
Protein kinase C zeta mediates cigarette smoke/aldehyde- and lipopolysaccharide-induced lung inflammation and histone modifications. J Biol Chem (2009) 1.07
RelA Ser276 phosphorylation-coupled Lys310 acetylation controls transcriptional elongation of inflammatory cytokines in respiratory syncytial virus infection. J Virol (2011) 1.06
Perspectives on translational and therapeutic aspects of SIRT1 in inflammaging and senescence. Biochem Pharmacol (2012) 1.06
Potentiation of tumor necrosis factor-induced NF-kappa B activation by deacetylase inhibitors is associated with a delayed cytoplasmic reappearance of I kappa B alpha. Mol Cell Biol (2003) 1.04
The Roles of SIRT1 in Cancer. Genes Cancer (2013) 1.04
Dendritic cells for active anti-cancer immunotherapy: targeting activation pathways through genetic modification. Endocr Metab Immune Disord Drug Targets (2009) 1.01
Regulation of NF-κB activity by competition between RelA acetylation and ubiquitination. Oncogene (2011) 1.01
Brd4 is essential for IL-1β-induced inflammation in human airway epithelial cells. PLoS One (2014) 1.01
Oxidative stress and chromatin remodeling in chronic obstructive pulmonary disease and smoking-related diseases. Antioxid Redox Signal (2012) 1.01
Benzyl isothiocyanate-mediated inhibition of histone deacetylase leads to NF-kappaB turnoff in human pancreatic carcinoma cells. Mol Cancer Ther (2010) 1.00
Glycogen synthase kinase-3β inactivation inhibits tumor necrosis factor-α production in microglia by modulating nuclear factor κB and MLK3/JNK signaling cascades. J Neuroinflammation (2010) 1.00
Inhibition of NF-kappaB by ZAS3, a zinc-finger protein that also binds to the kappaB motif. Proc Natl Acad Sci U S A (2003) 1.00
Leptin attenuates BACE1 expression and amyloid-β genesis via the activation of SIRT1 signaling pathway. Biochim Biophys Acta (2014) 1.00
Current perspectives on role of chromatin modifications and deacetylases in lung inflammation in COPD. COPD (2009) 0.99
Bortezomib interacts synergistically with belinostat in human acute myeloid leukaemia and acute lymphoblastic leukaemia cells in association with perturbations in NF-κB and Bim. Br J Haematol (2011) 0.99
Modification of RelA by O-linked N-acetylglucosamine links glucose metabolism to NF-κB acetylation and transcription. Proc Natl Acad Sci U S A (2012) 0.98
CBP mediates NF-κB-dependent histone acetylation and estrogen receptor recruitment to an estrogen response element in the BIRC3 promoter. Mol Cell Biol (2011) 0.98
Unique aspects of transcriptional regulation in neurons--nuances in NFkappaB and Sp1-related factors. J Neuroinflammation (2009) 0.98
ROCK I-mediated activation of NF-kappaB by RhoB. Cell Signal (2007) 0.98
Epigenetic control of HIV-1 post integration latency: implications for therapy. Clin Epigenetics (2015) 0.98
Epigenetic regulation of high glucose-induced proinflammatory cytokine production in monocytes by curcumin. J Nutr Biochem (2010) 0.97
Activation of the transcriptional function of the NF-κB protein c-Rel by O-GlcNAc glycosylation. Sci Signal (2013) 0.97
UXT is a novel and essential cofactor in the NF-kappaB transcriptional enhanceosome. J Cell Biol (2007) 0.97
HER-2 and NF-kappaB as the targets for therapy-resistant breast cancer. Anticancer Res (2007) 0.96
HIF1α protein stability is increased by acetylation at lysine 709. J Biol Chem (2012) 0.96
The NF-kappa B and I kappa B proteins: new discoveries and insights. Annu Rev Immunol (1996) 22.30
NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses. Annu Rev Immunol (1998) 21.48
Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain. Cell (1997) 16.79
Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-kappa B transcription factor. Cell (1988) 11.62
Structure and ligand of a histone acetyltransferase bromodomain. Nature (1999) 10.08
Acetylation of histones and transcription-related factors. Microbiol Mol Biol Rev (2000) 9.36
NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway. Science (1993) 9.03
Roles of histone acetyltransferases and deacetylases in gene regulation. Bioessays (1998) 7.79
Duration of nuclear NF-kappaB action regulated by reversible acetylation. Science (2001) 6.79
Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of I kappa B alpha: a mechanism for NF-kappa B activation. Mol Cell Biol (1993) 6.79
Structure of an IkappaBalpha/NF-kappaB complex. Cell (1998) 5.67
Mutual regulation of the transcriptional activator NF-kappa B and its inhibitor, I kappa B-alpha. Proc Natl Acad Sci U S A (1993) 4.99
The crystal structure of the IkappaBalpha/NF-kappaB complex reveals mechanisms of NF-kappaB inactivation. Cell (1998) 4.71
CREB-binding protein/p300 are transcriptional coactivators of p65. Proc Natl Acad Sci U S A (1997) 4.71
Regulation of activity of the transcription factor GATA-1 by acetylation. Nature (1998) 4.68
The p65 (RelA) subunit of NF-kappaB interacts with the histone deacetylase (HDAC) corepressors HDAC1 and HDAC2 to negatively regulate gene expression. Mol Cell Biol (2001) 4.55
Regulation of NF-kappaB by cyclin-dependent kinases associated with the p300 coactivator. Science (1997) 4.37
How NF-kappaB is activated: the role of the IkappaB kinase (IKK) complex. Oncogene (1999) 4.33
Regulation of E2F1 activity by acetylation. EMBO J (2000) 4.18
Crystal structure of p50/p65 heterodimer of transcription factor NF-kappaB bound to DNA. Nature (1998) 4.03
A viral mechanism for inhibition of p300 and PCAF acetyltransferase activity. Cell (1999) 3.36
Transcriptional activation by NF-kappaB requires multiple coactivators. Mol Cell Biol (1999) 3.11
Acetylation of HMG I(Y) by CBP turns off IFN beta expression by disrupting the enhanceosome. Mol Cell (1998) 3.09
Drosophila CBP represses the transcription factor TCF to antagonize Wingless signalling. Nature (1998) 2.98
The SRC family of nuclear receptor coactivators. Gene (2000) 2.96
Regulation of histone acetyltransferases p300 and PCAF by the bHLH protein twist and adenoviral oncoprotein E1A. Cell (1999) 2.90
IkappaB-NF-kappaB structures: at the interface of inflammation control. Cell (1998) 2.86
Biochemical analysis of distinct activation functions in p300 that enhance transcription initiation with chromatin templates. Mol Cell Biol (1999) 2.80
Inducible nuclear expression of newly synthesized I kappa B alpha negatively regulates DNA-binding and transcriptional activities of NF-kappa B. Mol Cell Biol (1995) 2.69
Nuclear localization of I kappa B alpha promotes active transport of NF-kappa B from the nucleus to the cytoplasm. J Cell Sci (1997) 2.44
The nuclear factor-kappaB engages CBP/p300 and histone acetyltransferase activity for transcriptional activation of the interleukin-6 gene promoter. J Biol Chem (1999) 2.15
Nuclear integration of glucocorticoid receptor and nuclear factor-kappaB signaling by CREB-binding protein and steroid receptor coactivator-1. J Biol Chem (1998) 2.02
Steroid receptor coactivator-1 interacts with the p50 subunit and coactivates nuclear factor kappaB-mediated transactivations. J Biol Chem (1998) 1.95
Acetylation by PCAF enhances CIITA nuclear accumulation and transactivation of major histocompatibility complex class II genes. Mol Cell Biol (2000) 1.95
Phosphorylation of IkappaBalpha in the C-terminal PEST domain by casein kinase II affects intrinsic protein stability. Mol Cell Biol (1996) 1.90
An N-terminal nuclear export signal is required for the nucleocytoplasmic shuttling of IkappaBalpha. EMBO J (1999) 1.88
Glucocorticoids repress NF-kappaB-driven genes by disturbing the interaction of p65 with the basal transcription machinery, irrespective of coactivator levels in the cell. Proc Natl Acad Sci U S A (2000) 1.87
E2F family members are differentially regulated by reversible acetylation. J Biol Chem (2000) 1.77
Functional interaction of the v-Rel and c-Rel oncoproteins with the TATA-binding protein and association with transcription factor IIB. Mol Cell Biol (1993) 1.70
Constitutive phosphorylation of IkappaBalpha by casein kinase II occurs preferentially at serine 293: requirement for degradation of free IkappaBalpha. Mol Cell Biol (1996) 1.67
HATs on and beyond chromatin. Curr Opin Cell Biol (2001) 1.66
Gene activation by histone and factor acetyltransferases. Curr Opin Cell Biol (1999) 1.65
The PEST-like sequence of I kappa B alpha is responsible for inhibition of DNA binding but not for cytoplasmic retention of c-Rel or RelA homodimers. Mol Cell Biol (1995) 1.64
RAC-3 is a NF-kappa B coactivator. FEBS Lett (2000) 1.64
Mutational analysis of the transcription activation domain of RelA: identification of a highly synergistic minimal acidic activation module. Mol Cell Biol (1994) 1.58
Interaction between acetylated MyoD and the bromodomain of CBP and/or p300. Mol Cell Biol (2001) 1.56
Transcription factor-dependent regulation of CBP and P/CAF histone acetyltransferase activity. EMBO J (2001) 1.55
Interaction of the COOH-terminal transactivation domain of p65 NF-kappa B with TATA-binding protein, transcription factor IIB, and coactivators. J Biol Chem (1995) 1.53
A phosphatidylinositol 3-kinase/Akt pathway, activated by tumor necrosis factor or interleukin-1, inhibits apoptosis but does not activate NFkappaB in human endothelial cells. J Biol Chem (2000) 1.46
Regulation of gene expression by transcription factor acetylation. Cell Mol Life Sci (2000) 1.35
Basal phosphorylation of the PEST domain in the I(kappa)B(beta) regulates its functional interaction with the c-rel proto-oncogene product. Mol Cell Biol (1996) 1.33
Transcription: gene control by targeted histone acetylation. Curr Biol (1998) 1.29
Regulation of the homeodomain CCAAT displacement/cut protein function by histone acetyltransferases p300/CREB-binding protein (CBP)-associated factor and CBP. Proc Natl Acad Sci U S A (2000) 1.15
The challenge of finding a cure for HIV infection. Science (2009) 8.41
HIV-1 Vif blocks the antiviral activity of APOBEC3G by impairing both its translation and intracellular stability. Mol Cell (2003) 7.42
Shaping the nuclear action of NF-kappaB. Nat Rev Mol Cell Biol (2004) 6.88
A sensitive and specific enzyme-based assay detecting HIV-1 virion fusion in primary T lymphocytes. Nat Biotechnol (2002) 5.49
Retracted Cellular APOBEC3G restricts HIV-1 infection in resting CD4+ T cells. Nature (2005) 5.28
NF-kappaB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation. EMBO J (2005) 4.35
The APOBEC3 cytidine deaminases: an innate defensive network opposing exogenous retroviruses and endogenous retroelements. Annu Rev Immunol (2008) 4.27
HIV vaccine research: the way forward. Science (2008) 3.86
NF-kappaB RelA phosphorylation regulates RelA acetylation. Mol Cell Biol (2005) 3.50
Abortive HIV infection mediates CD4 T cell depletion and inflammation in human lymphoid tissue. Cell (2010) 3.42
HIV latency. Cold Spring Harb Perspect Med (2011) 2.90
IFI16 DNA sensor is required for death of lymphoid CD4 T cells abortively infected with HIV. Science (2013) 2.68
High-molecular-mass APOBEC3G complexes restrict Alu retrotransposition. Proc Natl Acad Sci U S A (2006) 2.54
Prostratin antagonizes HIV latency by activating NF-kappaB. J Biol Chem (2004) 2.47
The CD16+ monocyte subset is more permissive to infection and preferentially harbors HIV-1 in vivo. J Immunol (2007) 2.41
The cationic properties of SEVI underlie its ability to enhance human immunodeficiency virus infection. J Virol (2008) 2.38
Compensatory link between fusion and endocytosis of human immunodeficiency virus type 1 in human CD4 T lymphocytes. J Virol (2004) 2.06
p53 induces NF-kappaB activation by an IkappaB kinase-independent mechanism involving phosphorylation of p65 by ribosomal S6 kinase 1. J Biol Chem (2004) 2.01
Apobec3 encodes Rfv3, a gene influencing neutralizing antibody control of retrovirus infection. Science (2008) 1.97
Guidelines for naming nonprimate APOBEC3 genes and proteins. J Virol (2008) 1.86
Regulation of distinct biological activities of the NF-kappaB transcription factor complex by acetylation. J Mol Med (Berl) (2003) 1.79
Endogenous factors enhance HIV infection of tissue naive CD4 T cells by stimulating high molecular mass APOBEC3G complex formation. J Exp Med (2006) 1.77
Sustained induction of NF-kappa B is required for efficient expression of latent human immunodeficiency virus type 1. J Virol (2007) 1.74
Peptides released by physiological cleavage of semen coagulum proteins form amyloids that enhance HIV infection. Cell Host Microbe (2011) 1.72
Semen-mediated enhancement of HIV infection is donor-dependent and correlates with the levels of SEVI. Retrovirology (2010) 1.70
Newly synthesized APOBEC3G is incorporated into HIV virions, inhibited by HIV RNA, and subsequently activated by RNase H. PLoS Pathog (2007) 1.70
In vitro derived dendritic cells trans-infect CD4 T cells primarily with surface-bound HIV-1 virions. PLoS Pathog (2007) 1.70
Distinct patterns of cytokine regulation of APOBEC3G expression and activity in primary lymphocytes, macrophages, and dendritic cells. J Biol Chem (2006) 1.68
An integrated overview of HIV-1 latency. Cell (2013) 1.68
Role of retroviral restriction factors in the interferon-α-mediated suppression of HIV-1 in vivo. Proc Natl Acad Sci U S A (2012) 1.65
Regulation of HIV-1 latency by T-cell activation. Cytokine (2007) 1.48
Human immunodeficiency virus type 1 Vpr induces DNA replication stress in vitro and in vivo. J Virol (2006) 1.47
Interleukin-18-induced human coronary artery smooth muscle cell migration is dependent on NF-kappaB- and AP-1-mediated matrix metalloproteinase-9 expression and is inhibited by atorvastatin. J Biol Chem (2006) 1.42
Naturally occurring fragments from two distinct regions of the prostatic acid phosphatase form amyloidogenic enhancers of HIV infection. J Virol (2011) 1.42
Nef is physically recruited into the immunological synapse and potentiates T cell activation early after TCR engagement. J Immunol (2005) 1.41
Aminoquinoline surfen inhibits the action of SEVI (semen-derived enhancer of viral infection). J Biol Chem (2009) 1.39
Slipping through the door: HIV entry into the nucleus. Microbes Infect (2002) 1.39
Human T-cell lymphotropic virus type 1 tax induction of biologically Active NF-kappaB requires IkappaB kinase-1-mediated phosphorylation of RelA/p65. J Biol Chem (2004) 1.38
Human immunodeficiency virus type 1 Tat protein inhibits the SIRT1 deacetylase and induces T cell hyperactivation. Cell Host Microbe (2008) 1.35
HIV-1 virion fusion assay: uncoating not required and no effect of Nef on fusion. Virology (2004) 1.34
Activation of HIV transcription by the viral Tat protein requires a demethylation step mediated by lysine-specific demethylase 1 (LSD1/KDM1). PLoS Pathog (2011) 1.31
Reprogramming somatic cells into iPS cells activates LINE-1 retroelement mobility. Hum Mol Genet (2011) 1.31
Fluorescence resonance energy transfer-based HIV-1 virion fusion assay. Methods Mol Biol (2004) 1.26
Lipid droplet-binding protein TIP47 regulates hepatitis C Virus RNA replication through interaction with the viral NS5A protein. PLoS Pathog (2013) 1.23
A flexible model of HIV-1 latency permitting evaluation of many primary CD4 T-cell reservoirs. PLoS One (2012) 1.23
Human immunodeficiency virus fusion to dendritic cells declines as cells mature. J Virol (2006) 1.22
NF-kappaB/Rel regulates inhibitory and excitatory neuronal function and synaptic plasticity. Mol Cell Biol (2006) 1.20
The achilles heel of the trojan horse model of HIV-1 trans-infection. PLoS Pathog (2008) 1.18
Endogenous APOBEC3B restricts LINE-1 retrotransposition in transformed cells and human embryonic stem cells. J Biol Chem (2011) 1.18
Dynamic roles for NF-κB in HTLV-I and HIV-1 retroviral pathogenesis. Immunol Rev (2012) 1.14
HIV-1 Vpr displays natural protein-transducing properties: implications for viral pathogenesis. Virology (2002) 1.14
Rodent cells support key functions of the human immunodeficiency virus type 1 pathogenicity factor Nef. J Virol (2005) 1.13
Multifaceted antiviral actions of APOBEC3 cytidine deaminases. Trends Immunol (2006) 1.12
Human immunodeficiency virus type 1 Nef-mediated downregulation of CD4 correlates with Nef enhancement of viral pathogenesis. J Virol (2003) 1.11
Lethal cutaneous disease in transgenic mice conditionally expressing type I human T cell leukemia virus Tax. J Biol Chem (2005) 1.10
Noninfectious retrovirus particles drive the APOBEC3/Rfv3 dependent neutralizing antibody response. PLoS Pathog (2011) 1.05
Cyclophilin A interacts with HIV-1 Vpr and is required for its functional expression. J Biol Chem (2003) 1.05
HIV-1 Vif versus the APOBEC3 cytidine deaminases: an intracellular duel between pathogen and host restriction factors. Mol Aspects Med (2010) 1.03
APOBEC3G: an intracellular centurion. Philos Trans R Soc Lond B Biol Sci (2009) 1.02
Insights into the biology of HIV-1 viral protein R. DNA Cell Biol (2002) 1.02
Nuclear export of Vpr is required for efficient replication of human immunodeficiency virus type 1 in tissue macrophages. J Virol (2003) 1.00
Innate retroviral restriction by Apobec3 promotes antibody affinity maturation in vivo. J Immunol (2010) 0.99
Differential transmission of HIV traversing fetal oral/intestinal epithelia and adult oral epithelia. J Virol (2011) 0.99
HIV is inactivated after transepithelial migration via adult oral epithelial cells but not fetal epithelial cells. Virology (2010) 0.99
Seminal plasma induces global transcriptomic changes associated with cell migration, proliferation and viability in endometrial epithelial cells and stromal fibroblasts. Hum Reprod (2014) 0.97
Enhanced fusion and virion incorporation for HIV-1 subtype C envelope glycoproteins with compact V1/V2 domains. J Virol (2013) 0.96
NF-κB/Rel: agonist and antagonist roles in HIV-1 latency. Curr Opin HIV AIDS (2011) 0.95
Primary T-cells from human CD4/CCR5-transgenic rats support all early steps of HIV-1 replication including integration, but display impaired viral gene expression. Retrovirology (2007) 0.94
Persistent Friend virus replication and disease in Apobec3-deficient mice expressing functional B-cell-activating factor receptor. J Virol (2010) 0.93
APOBEC3 cytidine deaminases: distinct antiviral actions along the retroviral life cycle. J Biol Chem (2005) 0.93
Assessing acetylation of NF-kappaB. Methods (2005) 0.92
A seminal finding for understanding HIV transmission. Cell (2007) 0.92
Host factors regulating post-integration latency of HIV. Trends Microbiol (2005) 0.90
Measuring HIV fusion mediated by envelopes from primary viral isolates. Methods (2010) 0.88
Identification of two APOBEC3F splice variants displaying HIV-1 antiviral activity and contrasting sensitivity to Vif. J Biol Chem (2010) 0.86
Protecting APOBEC3G: a potential new target for HIV drug discovery. Curr Opin Investig Drugs (2005) 0.85
Evasion of superinfection exclusion and elimination of primary viral RNA by an adapted strain of hepatitis C virus. J Virol (2013) 0.84
Calcium/calcineurin synergizes with prostratin to promote NF-κB dependent activation of latent HIV. PLoS One (2013) 0.84
Human cyclin T1 expression ameliorates a T-cell-specific transcriptional limitation for HIV in transgenic rats, but is not sufficient for a spreading infection of prototypic R5 HIV-1 strains ex vivo. Retrovirology (2009) 0.84
How resting T cells deMURR HIV infection. Nat Immunol (2004) 0.84
Rapid intracellular competition between hepatitis C viral genomes as a result of mitosis. J Virol (2012) 0.79
APOBEC3G and HIV-1: strike and counterstrike. Curr HIV/AIDS Rep (2007) 0.79
[Role of semen-derived amyloid fibrils as facilitators of HIV infection]. Med Sci (Paris) (2012) 0.76
APOBEC3G and HIV-1: strike and counterstrike. Curr Infect Dis Rep (2006) 0.76
Corrigendum: Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection. Nature (2017) 0.75
Redistricting the retroviral restriction factors. Nat Med (2004) 0.75
A plea for justice for jailed medical workers. Science (2006) 0.75
Unsung hero Robert C. Gallo. Science (2009) 0.75
Solutions to global health challenges: no more Band-Aids. J Clin Invest (2013) 0.75