Published in Nucleic Acids Res on January 01, 1976
Contacts between the lac repressor and the thymines in the lac operator. Proc Natl Acad Sci U S A (1977) 2.52
Secondary structural complementarity between DNA and proteins. Proc Natl Acad Sci U S A (1977) 1.39
Model for lactose repressor protein and its interaction with ligands. Proc Natl Acad Sci U S A (1980) 1.28
Binding of E.coli lac repressor to non-operator DNA. Nucleic Acids Res (1977) 1.22
lac repressor changes conformation upon binding to poly[dA-T)]. Proc Natl Acad Sci U S A (1979) 0.75
FURTHER STUDIES ON THE ALKYLATION OF NUCLEIC ACIDS AND THEIR CONSTITUENT NUCLEOTIDES. Biochem J (1963) 25.31
Isolation of the lac repressor. Proc Natl Acad Sci U S A (1966) 10.20
The lac repressor-operator interaction. 3. Kinetic studies. J Mol Biol (1970) 10.07
Lac repressor binding to non-operator DNA: detailed studies and a comparison of eequilibrium and rate competition methods. J Mol Biol (1972) 5.62
The general affinity of lac repressor for E. coli DNA: implications for gene regulation in procaryotes and eucaryotes. Cell (1975) 3.73
The chemical effects of nucleic acid alkylation and their relation to mutagenesis and carcinogenesis. Prog Nucleic Acid Res Mol Biol (1975) 2.93
Lac repressor binding to poly (d(A-T)). Conformational changes. Biochem Biophys Res Commun (1974) 2.49
Studies with glucosyl transferase mutants of the T-even bacteriophages. Virology (1971) 1.82
Lac repressor binding to operator analogues: comparison of poly(d(A-T)), poly(d(A-BrU)), and poly(d(A-U)). Biochem Biophys Res Commun (1971) 1.62
Lac repressor binding to synthetic DNAs of defined nucleotide sequence. Proc Natl Acad Sci U S A (1972) 1.26
[Structure of the complexes of distamycin type antibiotics and actinomycin D with DNA: new data on the localization of these antibiotics within the DNA narrow groove]. Mol Biol (Mosk) (1976) 0.90
Sequencing end-labeled DNA with base-specific chemical cleavages. Methods Enzymol (1980) 287.68
A new method for sequencing DNA. Proc Natl Acad Sci U S A (1977) 250.51
Genomic sequencing. Proc Natl Acad Sci U S A (1984) 92.36
Mapping adenines, guanines, and pyrimidines in RNA. Nucleic Acids Res (1977) 26.63
E. coli RNA polymerase interacts homologously with two different promoters. Cell (1980) 19.71
Why genes in pieces? Nature (1978) 19.03
Nucleotide sequence of Rous sarcoma virus. Cell (1983) 17.80
Immunological screening method to detect specific translation products. Proc Natl Acad Sci U S A (1978) 17.80
Molecular basis of base substitution hotspots in Escherichia coli. Nature (1978) 13.79
Construction of plasmids carrying the cI gene of bacteriophage lambda. Proc Natl Acad Sci U S A (1976) 13.10
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell (2000) 11.90
The nucleotide sequence of the lac operator. Proc Natl Acad Sci U S A (1973) 11.28
Hepatitis B virus genes and their expression in E. coli. Nature (1979) 10.83
The evolution of genes: the chicken preproinsulin gene. Cell (1980) 10.25
A bacterial clone synthesizing proinsulin. Proc Natl Acad Sci U S A (1978) 10.23
B lineage--specific interactions of an immunoglobulin enhancer with cellular factors in vivo. Science (1985) 9.73
Contacts between Escherichia coli RNA polymerase and an early promoter of phage T7. Proc Natl Acad Sci U S A (1980) 9.32
The structure and evolution of the two nonallelic rat preproinsulin genes. Cell (1979) 9.25
Formation of parallel four-stranded complexes by guanine-rich motifs in DNA and its implications for meiosis. Nature (1988) 8.58
DNA replication: the rolling circle model. Cold Spring Harb Symp Quant Biol (1968) 8.37
Absence of polymorphism at the ZFY locus on the human Y chromosome. Science (1995) 7.86
Rous sarcoma virus genome is terminally redundant: the 5' sequence. Proc Natl Acad Sci U S A (1977) 7.09
Role of LXRs in control of lipogenesis. Genes Dev (2000) 6.98
Sequence of a mouse germ-line gene for a variable region of an immunoglobulin light chain. Proc Natl Acad Sci U S A (1978) 6.80
Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers. Science (2000) 6.52
Mutants that make more lac repressor. Proc Natl Acad Sci U S A (1968) 6.26
The genetic data environment an expandable GUI for multiple sequence analysis. Comput Appl Biosci (1994) 5.68
Chemical probes for higher-order structure in RNA. Proc Natl Acad Sci U S A (1980) 5.38
A sodium-potassium switch in the formation of four-stranded G4-DNA. Nature (1990) 5.35
The lac operator is DNA. Proc Natl Acad Sci U S A (1967) 5.24
Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway. Mol Cell (2001) 5.19
Arrhythmogenesis and contractile dysfunction in heart failure: Roles of sodium-calcium exchange, inward rectifier potassium current, and residual beta-adrenergic responsiveness. Circ Res (2001) 5.08
The GA5 locus of Arabidopsis thaliana encodes a multifunctional gibberellin 20-oxidase: molecular cloning and functional expression. Proc Natl Acad Sci U S A (1995) 4.80
Parallel thermodynamic analysis of duplexes on oligodeoxyribonucleotide microchips. Nucleic Acids Res (1998) 4.18
Infectivity, transmission, and pathology of human-isolated H7N9 influenza virus in ferrets and pigs. Science (2013) 4.17
The FET3 gene of S. cerevisiae encodes a multicopper oxidase required for ferrous iron uptake. Cell (1994) 4.12
Activin receptor-like kinase 1 modulates transforming growth factor-beta 1 signaling in the regulation of angiogenesis. Proc Natl Acad Sci U S A (2000) 4.08
The lac repressor and the lac operator. Ciba Found Symp (1972) 4.01
From ab initio quantum mechanics to molecular neurobiology: a cation-pi binding site in the nicotinic receptor. Proc Natl Acad Sci U S A (1998) 3.99
An amino-terminal fragment of lac repressor binds specifically to lac operator. Proc Natl Acad Sci U S A (1978) 3.98
Akt activation preserves cardiac function and prevents injury after transient cardiac ischemia in vivo. Circulation (2001) 3.98
Cell-type-specific contacts to immunoglobulin enhancers in nuclei. Nature (1985) 3.94
MSI and MSII made on ribosome in idling step of protein synthesis. Nature (1972) 3.89
Immunobiochemical and molecular biologic characterization of the cell proliferation-associated nuclear antigen that is defined by monoclonal antibody Ki-67. Am J Pathol (1991) 3.82
Role of CD8(+) lymphocytes in control of simian immunodeficiency virus infection and resistance to rechallenge after transient early antiretroviral treatment. J Virol (2001) 3.40
Patterning of muscle acetylcholine receptor gene expression in the absence of motor innervation. Neuron (2001) 3.37
Whole-body optical imaging of green fluorescent protein-expressing tumors and metastases. Proc Natl Acad Sci U S A (2000) 3.24
How big is the universe of exons? Science (1990) 3.16
Determinants of car travel on daily journeys to school: cross sectional survey of primary school children. BMJ (1998) 3.11
'Seed' analysis of off-target siRNAs reveals an essential role of Mcl-1 in resistance to the small-molecule Bcl-2/Bcl-XL inhibitor ABT-737. Oncogene (2006) 3.10
Localization of chromatin proteins within DNA grooves by methylation of chromatin with dimethyl sulphate. Mol Biol Rep (1974) 3.04
Activity of neurons in anterior inferior temporal cortex during a short-term memory task. J Neurosci (1993) 3.04
On the antiquity of introns. Cell (1986) 2.98
Intron phase correlations and the evolution of the intron/exon structure of genes. Proc Natl Acad Sci U S A (1995) 2.98
Dapagliflozin, a novel SGLT2 inhibitor, induces dose-dependent glucosuria in healthy subjects. Clin Pharmacol Ther (2009) 2.98
Dapagliflozin, a novel, selective SGLT2 inhibitor, improved glycemic control over 2 weeks in patients with type 2 diabetes mellitus. Clin Pharmacol Ther (2009) 2.96
The triosephosphate isomerase gene from maize: introns antedate the plant-animal divergence. Cell (1986) 2.95
New tricks for modelers from the crystallography toolkit: the particle mesh Ewald algorithm and its use in nucleic acid simulations. Structure (1999) 2.92
A neural mechanism for working and recognition memory in inferior temporal cortex. Science (1991) 2.86
Search for a resonance decaying into WZ boson pairs in pp collisions. Phys Rev Lett (2010) 2.83
Oligonucleotide microchips as genosensors for determinative and environmental studies in microbiology. Appl Environ Microbiol (1997) 2.83
Eukaryotic signal sequence transports insulin antigen in Escherichia coli. Proc Natl Acad Sci U S A (1980) 2.79
The Cockayne syndrome group A gene encodes a WD repeat protein that interacts with CSB protein and a subunit of RNA polymerase II TFIIH. Cell (1995) 2.78
Global gene expression profiles of Bacillus subtilis grown under anaerobic conditions. J Bacteriol (2000) 2.77
Mitochondrial endonuclease G is important for apoptosis in C. elegans. Nature (2001) 2.76
Prism adaptation to a rightward optical deviation rehabilitates left hemispatial neglect. Nature (1998) 2.74
Genes-in-pieces revisited. Science (1985) 2.72
Towards a paradigm shift in biology. Nature (1991) 2.70
A method for DNA sequencing by hybridization with oligonucleotide matrix. DNA Seq (1991) 2.70
From hematopoiesis to neuropoiesis: evidence of overlapping genetic programs. Proc Natl Acad Sci U S A (2001) 2.66
Multiple novel astrovirus species in human stool. J Gen Virol (2009) 2.63
Ultrastructural evidence for hair cell regeneration in the mammalian inner ear. Science (1993) 2.62
EID: the Exon-Intron Database-an exhaustive database of protein-coding intron-containing genes. Nucleic Acids Res (2000) 2.56
Contacts between the lac repressor and the thymines in the lac operator. Proc Natl Acad Sci U S A (1977) 2.52
Change in the pattern of histone binding to DNA upon transcriptional activation. Cell (1989) 2.44
Analysis of trends in deaths from accidental drug poisoning in teenagers, 1985-95. BMJ (1997) 2.44
Nobel laureates' letter to President Bush. Washington Post (2001) 2.43
Fluorescence and photobleaching dynamics of single light-harvesting complexes. Proc Natl Acad Sci U S A (1997) 2.42
Adenoviral gene transfer of activated phosphatidylinositol 3'-kinase and Akt inhibits apoptosis of hypoxic cardiomyocytes in vitro. Circulation (1999) 2.40
Implications of a new dietary measurement error model for estimation of relative risk: application to four calibration studies. Am J Epidemiol (1999) 2.40
Influence of changing travel patterns on child death rates from injury: trend analysis. BMJ (1997) 2.37
Molecular cloning and photoperiod-regulated expression of gibberellin 20-oxidase from the long-day plant spinach. Plant Physiol (1996) 2.36
Promotor region for yeast 5S ribosomal RNA. Nature (1977) 2.32
Mutations of tau protein in frontotemporal dementia promote aggregation of paired helical filaments by enhancing local beta-structure. J Biol Chem (2001) 2.32
Phylogeny of the Simbu serogroup of the genus Bunyavirus. J Gen Virol (2001) 2.30
Rous sarcoma virus encodes a transcriptional activator. Cell (1985) 2.28
A role for destabilizing amino acid replacements in light-chain amyloidosis. Proc Natl Acad Sci U S A (1994) 2.27
Translocation of a calcium-permeable cation channel induced by insulin-like growth factor-I. Nat Cell Biol (1999) 2.25
One-sided polymerase chain reaction: the amplification of cDNA. Proc Natl Acad Sci U S A (1989) 2.25
Overview of the MHC fine mapping data. Diabetes Obes Metab (2009) 2.24
Containment of simian immunodeficiency virus infection: cellular immune responses and protection from rechallenge following transient postinoculation antiretroviral treatment. J Virol (2000) 2.24
Cardiac defects and renal failure in mice with targeted mutations in Pkd2. Nat Genet (2000) 2.24
The ErbB2 and ErbB3 receptors and their ligand, neuregulin-1, are essential for development of the sympathetic nervous system. Genes Dev (1998) 2.23
Disturbed sleep: effects of sociocultural factors and illness. Arch Dis Child (1998) 2.23
5 s RNA conformation. Studies of its partial T 1 ribonuclease digestion by gel electrophoresis and two-dimensional thin-layer chromatography. J Mol Biol (1972) 2.21
DNA-binding site of lac repressor probed by dimethylsulfate methylation of lac operator. J Mol Biol (1979) 2.20
Cellular location affects protein stability in Escherichia coli. Proc Natl Acad Sci U S A (1982) 2.20
The looming epidemic of diabetes-associated tuberculosis: learning lessons from HIV-associated tuberculosis. Int J Tuberc Lung Dis (2011) 2.19
Population and familial association between the D4 dopamine receptor gene and measures of Novelty Seeking. Nat Genet (1996) 2.18
Ginsenoside-Rd improves outcome of acute ischaemic stroke - a randomized, double-blind, placebo-controlled, multicenter trial. Eur J Neurol (2012) 2.18