Published in Arthritis Rheum on January 01, 2003
Regulatory polymorphisms underlying complex disease traits. J Mol Med (Berl) (2004) 3.22
Distinct roles for lymphotoxin-alpha and tumor necrosis factor in the control of Leishmania donovani infection. Am J Pathol (2004) 1.17
Genetics of inflammatory bowel disease: the role of the HLA complex. World J Gastroenterol (2006) 0.89
Common variants at the promoter region of the APOM confer a risk of rheumatoid arthritis. Exp Mol Med (2011) 0.87
Gene polymorphisms and pharmacogenetics in rheumatoid arthritis. Curr Genomics (2008) 0.80
Tumour necrosis factor allele variants and their association with the occurrence and severity of malaria in African children: a longitudinal study. Malar J (2015) 0.76
Distribution of TNFA haplotypes in healthy Caucasians: comment on the articles by Newton et al and Zeggini et al. Arthritis Rheum (2004) 0.75
Detecting recent positive selection in the human genome from haplotype structure. Nature (2002) 22.00
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature (2011) 13.23
Five years of GWAS discovery. Am J Hum Genet (2012) 12.97
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nat Genet (2007) 12.62
Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls. Nature (2010) 12.27
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. Nat Genet (2010) 9.90
A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1. Nat Genet (2010) 8.48
Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Nat Genet (2013) 7.44
A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva. Nat Genet (2006) 7.05
Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility. Nat Genet (2011) 5.56
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nat Genet (2012) 5.48
Promise and pitfalls of the Immunochip. Arthritis Res Ther (2011) 5.38
Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region. Nat Genet (2009) 4.61
Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes. Nat Genet (2010) 4.42
Whole-genome linkage analysis of rheumatoid arthritis susceptibility loci in 252 affected sibling pairs in the United Kingdom. Arthritis Rheum (2002) 3.78
Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci. Nat Genet (2010) 3.58
Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci. Ann Neurol (2011) 3.52
Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke. Nat Genet (2012) 3.40
Dissection of the genetics of Parkinson's disease identifies an additional association 5' of SNCA and multiple associated haplotypes at 17q21. Hum Mol Genet (2010) 3.34
Bayesian refinement of association signals for 14 loci in 3 common diseases. Nat Genet (2012) 3.31
CISH and susceptibility to infectious diseases. N Engl J Med (2010) 3.31
Identification of IL6R and chromosome 11q13.5 as risk loci for asthma. Lancet (2011) 3.03
Efficacy and safety of adalimumab in patients with non-radiographic axial spondyloarthritis: results of a randomised placebo-controlled trial (ABILITY-1). Ann Rheum Dis (2012) 3.00
Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci. Nat Genet (2013) 2.87
Genetic insights into common pathways and complex relationships among immune-mediated diseases. Nat Rev Genet (2013) 2.85
Potent CD8+ T-cell immunogenicity in humans of a novel heterosubtypic influenza A vaccine, MVA-NP+M1. Clin Infect Dis (2011) 2.71
Mosaic PPM1D mutations are associated with predisposition to breast and ovarian cancer. Nature (2012) 2.66
Control of HIV-1 immune escape by CD8 T cells expressing enhanced T-cell receptor. Nat Med (2008) 2.64
Standardized data collection for multi-center clinical studies of severe malaria in African children: establishing the SMAC network. Trans R Soc Trop Med Hyg (2006) 2.52
Association of variants at 1q32 and STAT3 with ankylosing spondylitis suggests genetic overlap with Crohn's disease. PLoS Genet (2010) 2.44
Genome-wide association study identifies susceptibility loci for open angle glaucoma at TMCO1 and CDKN2B-AS1. Nat Genet (2011) 2.42
Genome-wide association study using extreme truncate selection identifies novel genes affecting bone mineral density and fracture risk. PLoS Genet (2011) 2.34
Clearance of drug-resistant parasites as a model for protective immunity in Plasmodium falciparum malaria. Am J Trop Med Hyg (2003) 2.29
Whole-exome re-sequencing in a family quartet identifies POP1 mutations as the cause of a novel skeletal dysplasia. PLoS Genet (2011) 2.23
Ethical issues in human genomics research in developing countries. BMC Med Ethics (2011) 2.02
Common variants in the region around Osterix are associated with bone mineral density and growth in childhood. Hum Mol Genet (2009) 1.99
Identification of common genetic variation that modulates alternative splicing. PLoS Genet (2007) 1.96
Different T cell receptor affinity thresholds and CD8 coreceptor dependence govern cytotoxic T lymphocyte activation and tetramer binding properties. J Biol Chem (2007) 1.95
Investigating the genetic association between ERAP1 and ankylosing spondylitis. Hum Mol Genet (2009) 1.95
Interaction between the CD8 coreceptor and major histocompatibility complex class I stabilizes T cell receptor-antigen complexes at the cell surface. J Biol Chem (2005) 1.92
Common variants at 12q14 and 12q24 are associated with hippocampal volume. Nat Genet (2012) 1.79
Inflammatory bowel disease is associated with a TNF polymorphism that affects an interaction between the OCT1 and NF(-kappa)B transcription factors. Hum Mol Genet (2002) 1.76
Crystal structures of the endoplasmic reticulum aminopeptidase-1 (ERAP1) reveal the molecular basis for N-terminal peptide trimming. Proc Natl Acad Sci U S A (2011) 1.64
Genetic analyses in a sample of individuals with high or low BMD shows association with multiple Wnt pathway genes. J Bone Miner Res (2008) 1.58
Seeking consent to genetic and genomic research in a rural Ghanaian setting: a qualitative study of the MalariaGEN experience. BMC Med Ethics (2012) 1.55
Association of ERAP1, but not IL23R, with ankylosing spondylitis in a Han Chinese population. Arthritis Rheum (2009) 1.55
CD8+ T effector memory cells protect against liver-stage malaria. J Immunol (2011) 1.55
WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk. PLoS Genet (2012) 1.55
Quantitative prediction of NF-kappa B DNA-protein interactions. Proc Natl Acad Sci U S A (2002) 1.54
Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus. Nat Genet (2012) 1.52
Defects in the IFT-B component IFT172 cause Jeune and Mainzer-Saldino syndromes in humans. Am J Hum Genet (2013) 1.51
Whole exome sequencing is an efficient and sensitive method for detection of germline mutations in patients with phaeochromcytomas and paragangliomas. Clin Endocrinol (Oxf) (2013) 1.46
Genetics and genomics of ankylosing spondylitis. Immunol Rev (2010) 1.42
ANKH and susceptibility to and severity of ankylosing spondylitis. J Rheumatol (2011) 1.40
A polymorphism in the HLA-DPB1 gene is associated with susceptibility to multiple sclerosis. PLoS One (2010) 1.38
Site and gender specificity of inheritance of bone mineral density. J Bone Miner Res (2003) 1.30
Enrichment of circulating interleukin-17-secreting interleukin-23 receptor-positive γ/δ T cells in patients with active ankylosing spondylitis. Arthritis Rheum (2012) 1.29
Genetics of ankylosing spondylitis. Mol Immunol (2013) 1.29
Novel mutations in ACVR1 result in atypical features in two fibrodysplasia ossificans progressiva patients. PLoS One (2009) 1.29
Saliva-derived DNA performs well in large-scale, high-density single-nucleotide polymorphism microarray studies. Cancer Epidemiol Biomarkers Prev (2010) 1.27
Excessive bone formation in a mouse model of ankylosing spondylitis is associated with decreases in Wnt pathway inhibitors. Arthritis Res Ther (2012) 1.26
The interleukin 1 gene cluster contains a major susceptibility locus for ankylosing spondylitis. Am J Hum Genet (2004) 1.24
Autosomal dominant familial calcium pyrophosphate dihydrate deposition disease is caused by mutation in the transmembrane protein ANKH. Am J Hum Genet (2002) 1.23
Linkage and association studies of single-nucleotide polymorphism-tagged tumor necrosis factor haplotypes in juvenile oligoarthritis. Arthritis Rheum (2002) 1.21
Short-rib polydactyly and Jeune syndromes are caused by mutations in WDR60. Am J Hum Genet (2013) 1.20
High-throughput analysis of candidate imprinted genes and allele-specific gene expression in the human term placenta. BMC Genet (2010) 1.18
Co-introgression of Y-chromosome haplogroups and the sickle cell gene across Africa's Sahel. Eur J Hum Genet (2007) 1.18
Multistage genome-wide association meta-analyses identified two new loci for bone mineral density. Hum Mol Genet (2013) 1.17
The requirement for potent adjuvants to enhance the immunogenicity and protective efficacy of protein vaccines can be overcome by prior immunization with a recombinant adenovirus. J Immunol (2011) 1.17
Classical sickle beta-globin haplotypes exhibit a high degree of long-range haplotype similarity in African and Afro-Caribbean populations. BMC Genet (2007) 1.16
Mutations in the gene encoding IFT dynein complex component WDR34 cause Jeune asphyxiating thoracic dystrophy. Am J Hum Genet (2013) 1.16
Common variants in the HLA-DRB1-HLA-DQA1 HLA class II region are associated with susceptibility to visceral leishmaniasis. Nat Genet (2013) 1.15
Dissection of class III major histocompatibility complex haplotypes associated with rheumatoid arthritis. Arthritis Rheum (2004) 1.15
Association of STAT3 and TNFRSF1A with ankylosing spondylitis in Han Chinese. Ann Rheum Dis (2010) 1.14
Influence of LRP5 polymorphisms on normal variation in BMD. J Bone Miner Res (2004) 1.14
Association between the interleukin 23 receptor and ankylosing spondylitis is confirmed by a new UK case-control study and meta-analysis of published series. Rheumatology (Oxford) (2009) 1.13
A national DNA bank in The Gambia, West Africa, and genomic research in developing countries. Nat Genet (2004) 1.13
Integrated genome-wide chromatin occupancy and expression analyses identify key myeloid pro-differentiation transcription factors repressed by Myb. Nucleic Acids Res (2011) 1.13
Prevalence and boosting of antibodies to Plasmodium falciparum glycosylphosphatidylinositols and evaluation of their association with protection from mild and severe clinical malaria. Infect Immun (2002) 1.12
Does the microbiome play a causal role in spondyloarthritis? Clin Rheumatol (2014) 1.12
A novel serogenetic approach determines the community prevalence of celiac disease and informs improved diagnostic pathways. BMC Med (2013) 1.11
β-glucan triggers spondylarthritis and Crohn's disease-like ileitis in SKG mice. Arthritis Rheum (2012) 1.10
Optical imaging and analysis of human vaginal coating by drug delivery gels. Contraception (2006) 1.10
IFNGR1 gene promoter polymorphisms and susceptibility to cerebral malaria. J Infect Dis (2002) 1.09
Gene expression profiling reveals a downregulation in immune-associated genes in patients with AS. Ann Rheum Dis (2009) 1.08