Published in Cell Cycle on December 22, 2008
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Polycomb repressive complex 2 regulates normal development of the mouse heart. Circ Res (2011) 2.05
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Case records of the Massachusetts General Hospital: Case 5-2014: 2014: A 59-year-old man with fever, confusion, thrombocytopenia, rash, and renal failure. N Engl J Med (2014) 2.00
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Repression of the Arf tumor suppressor by E2F3 is required for normal cell cycle kinetics. Genes Dev (2004) 1.97
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Bmi1 is critical for lung tumorigenesis and bronchioalveolar stem cell expansion. Proc Natl Acad Sci U S A (2008) 1.90
Natriuretic peptide system gene variants are associated with ventricular dysfunction after coronary artery bypass grafting. Anesthesiology (2009) 1.85
IgG4-related systemic disease accounts for a significant proportion of thoracic lymphoplasmacytic aortitis cases. Arthritis Care Res (Hoboken) (2010) 1.83
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A novel COL1A1 mutation in infantile cortical hyperostosis (Caffey disease) expands the spectrum of collagen-related disorders. J Clin Invest (2005) 1.68
Loss of p53 synthesis in zebrafish tumors with ribosomal protein gene mutations. Proc Natl Acad Sci U S A (2008) 1.63
The T-Box transcription factor Tbx5 is required for the patterning and maturation of the murine cardiac conduction system. Development (2004) 1.59
Role of cardiac myosin binding protein C in sustaining left ventricular systolic stiffening. Circ Res (2004) 1.52
E2F3 loss has opposing effects on different pRB-deficient tumors, resulting in suppression of pituitary tumors but metastasis of medullary thyroid carcinomas. Mol Cell Biol (2003) 1.50
E2F4 loss suppresses tumorigenesis in Rb mutant mice. Cancer Cell (2002) 1.48
Myeloperoxidase-rich Ly-6C+ myeloid cells infiltrate allografts and contribute to an imaging signature of organ rejection in mice. J Clin Invest (2010) 1.48
Myc-mediated proliferation and lymphomagenesis, but not apoptosis, are compromised by E2f1 loss. Mol Cell (2003) 1.47
A vertebrate gene, ticrr, is an essential checkpoint and replication regulator. Genes Dev (2010) 1.47
Characterizing cardiopulmonary arrest during interventional radiology procedures. J Vasc Interv Radiol (2013) 1.45
IgG4-related systemic disease and lymphoplasmacytic aortitis. Arthritis Rheum (2009) 1.44
Mutant mouse models reveal the relative roles of E2F1 and E2F3 in vivo. Mol Cell Biol (2002) 1.44
The retinoblastoma protein tumor suppressor is important for appropriate osteoblast differentiation and bone development. Mol Cancer Res (2008) 1.43
Lamin A/C haploinsufficiency causes dilated cardiomyopathy and apoptosis-triggered cardiac conduction system disease. J Mol Cell Cardiol (2007) 1.42
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Somatic events modify hypertrophic cardiomyopathy pathology and link hypertrophy to arrhythmia. Proc Natl Acad Sci U S A (2005) 1.38
Dissecting spatio-temporal protein networks driving human heart development and related disorders. Mol Syst Biol (2010) 1.35
Loss-of-function mutations in the PRPS1 gene cause a type of nonsyndromic X-linked sensorineural deafness, DFN2. Am J Hum Genet (2010) 1.34
Rescue of cardiomyocyte dysfunction by phospholamban ablation does not prevent ventricular failure in genetic hypertrophy. J Clin Invest (2003) 1.33
IL-12 is required for differentiation of pathogenic CD8+ T cell effectors that cause myocarditis. J Clin Invest (2003) 1.31
Comparative proteomics profiling of a phospholamban mutant mouse model of dilated cardiomyopathy reveals progressive intracellular stress responses. Mol Cell Proteomics (2007) 1.31
Cardiac myosin missense mutations cause dilated cardiomyopathy in mouse models and depress molecular motor function. Proc Natl Acad Sci U S A (2006) 1.29
The retinoblastoma protein induces apoptosis directly at the mitochondria. Genes Dev (2013) 1.28
Many ribosomal protein mutations are associated with growth impairment and tumor predisposition in zebrafish. Dev Dyn (2009) 1.27
Coronary artery perforation by cutting balloon resulting in dissecting subepicardial hematoma and avulsion of the vasculature. Catheter Cardiovasc Interv (2005) 1.26
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2011 consensus statement on endomyocardial biopsy from the Association for European Cardiovascular Pathology and the Society for Cardiovascular Pathology. Cardiovasc Pathol (2011) 1.24
Deletion of thioredoxin-interacting protein in mice impairs mitochondrial function but protects the myocardium from ischemia-reperfusion injury. J Clin Invest (2011) 1.21
Activation of multiple signaling pathways causes developmental defects in mice with a Noonan syndrome–associated Sos1 mutation. J Clin Invest (2010) 1.21
Electrophysiologic characterization and postnatal development of ventricular pre-excitation in a mouse model of cardiac hypertrophy and Wolff-Parkinson-White syndrome. J Am Coll Cardiol (2003) 1.19
Effect of cardiac myosin binding protein-C on mechanoenergetics in mouse myocardium. Circ Res (2004) 1.19
Heterozygous knockout of neuregulin-1 gene in mice exacerbates doxorubicin-induced heart failure. Am J Physiol Heart Circ Physiol (2005) 1.18
A novel custom resequencing array for dilated cardiomyopathy. Genet Med (2010) 1.18
New treatment strategies in large-vessel vasculitis. Curr Opin Rheumatol (2013) 1.17
Chronic traumatic encephalopathy: clinical-biomarker correlations and current concepts in pathogenesis. Mol Neurodegener (2014) 1.15
Genetics of hypertrophic cardiomyopathy. Curr Opin Cardiol (2010) 1.14
Traumatically induced axotomy adjacent to the soma does not result in acute neuronal death. J Neurosci (2002) 1.13
SGLT1 is a novel cardiac glucose transporter that is perturbed in disease states. Cardiovasc Res (2009) 1.12
Aldosterone and not plasminogen activator inhibitor-1 is a critical mediator of early angiotensin II/NG-nitro-L-arginine methyl ester-induced myocardial injury. Circulation (2003) 1.12
E2f4 is required for normal development of the airway epithelium. Dev Biol (2007) 1.11
The SCAN domain defines a large family of zinc finger transcription factors. Gene (2003) 1.10
Heterozygosity for a loss-of-function mutation in GALNT2 improves plasma triglyceride clearance in man. Cell Metab (2011) 1.09
Painting blood vessels and atherosclerotic plaques with an adhesive drug depot. Proc Natl Acad Sci U S A (2012) 1.09
Genetic and environmental risk factors in congenital heart disease functionally converge in protein networks driving heart development. Proc Natl Acad Sci U S A (2012) 1.08
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Case records of the Massachusetts General Hospital. Case 28-2010. A 32-year-old woman, 3 weeks post partum, with substernal chest pain. N Engl J Med (2010) 1.07
Cell cycle genes are the evolutionarily conserved targets of the E2F4 transcription factor. PLoS One (2007) 1.07
Selective requirements for E2f3 in the development and tumorigenicity of Rb-deficient chimeric tissues. Mol Cell Biol (2007) 1.07
Giant cell myocarditis in a 12-year-old girl with common variable immunodeficiency. Mayo Clin Proc (2002) 1.06
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A dynamic H3K27ac signature identifies VEGFA-stimulated endothelial enhancers and requires EP300 activity. Genome Res (2013) 1.05
Optimizing catecholaminergic polymorphic ventricular tachycardia therapy in calsequestrin-mutant mice. Heart Rhythm (2010) 1.03
Dense IgG4 plasma cell infiltrates associated with chronic infectious aortitis: implications for the diagnosis of IgG4-related disease. Cardiovasc Pathol (2012) 1.03
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Transcription factor genes Smad4 and Gata4 cooperatively regulate cardiac valve development. [corrected] Proc Natl Acad Sci U S A (2011) 1.02