Published in Mol Cell on September 01, 2000
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p107 inhibits G1 to S phase progression by down-regulating expression of the F-box protein Skp2. J Cell Biol (2005) 1.03
Distinct roles of E2F proteins in vascular smooth muscle cell proliferation and intimal hyperplasia. Proc Natl Acad Sci U S A (2007) 1.01
Context-dependent requirement for dE2F during oncogenic proliferation. PLoS Genet (2008) 1.00
Overexpression of E2F-5 correlates with a pathological basal phenotype and a worse clinical outcome. Br J Cancer (2009) 0.99
Mullerian Inhibiting Substance inhibits cervical cancer cell growth via a pathway involving p130 and p107. Proc Natl Acad Sci U S A (2003) 0.98
let-7 and miR-140 microRNAs coordinately regulate skeletal development. Proc Natl Acad Sci U S A (2013) 0.98
Inhibition of pituitary tumors in Rb mutant chimeras through E2f4 loss reveals a key suppressive role for the pRB/E2F pathway in urothelium and ganglionic carcinogenesis. Oncogene (2008) 0.98
Lin9, a subunit of the mammalian DREAM complex, is essential for embryonic development, for survival of adult mice, and for tumor suppression. Mol Cell Biol (2010) 0.97
Small molecule regulators of Rb-E2F pathway as modulators of transcription. Biochim Biophys Acta (2010) 0.97
A retinoblastoma allele that is mutated at its common E2F interaction site inhibits cell proliferation in gene-targeted mice. Mol Cell Biol (2014) 0.95
Overexpression of cyclin E/CDK2 complexes overcomes FGF-induced cell cycle arrest in the presence of hypophosphorylated Rb proteins. Cell Cycle (2012) 0.94
The role of E2F4 in adipogenesis is independent of its cell cycle regulatory activity. Proc Natl Acad Sci U S A (2003) 0.93
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Constitutive E2F1 overexpression delays endochondral bone formation by inhibiting chondrocyte differentiation. Mol Cell Biol (2003) 0.91
Dissecting the contribution of p16(INK4A) and the Rb family to the Ras transformed phenotype. Mol Cell Biol (2003) 0.90
A potential oncogenic role of the commonly observed E2F5 overexpression in hepatocellular carcinoma. World J Gastroenterol (2011) 0.89
The retinoblastoma protein selectively represses E2F1 targets via a TAAC DNA element during cellular senescence. J Biol Chem (2012) 0.87
Selective roles of E2Fs for ErbB2- and Myc-mediated mammary tumorigenesis. Oncogene (2013) 0.86
Multilayered chromatin analysis reveals E2f, Smad and Zfx as transcriptional regulators of histones. Nat Struct Mol Biol (2012) 0.86
The MYC/miR-17-92 axis in lymphoproliferative disorders: A common pathway with therapeutic potential. Oncotarget (2015) 0.84
Disruption of calvarial ossification in E2f4 mutant embryos correlates with increased proliferation and progenitor cell populations. Cell Cycle (2010) 0.82
E2F4 cooperates with pRB in the development of extra-embryonic tissues. Dev Biol (2009) 0.82
Overexpression of E2F5/p130, but not E2F5 alone, can inhibit E2F-induced cell cycle entry in transgenic mice. Mol Vis (2008) 0.82
JAK3/STAT5/6 pathway alterations are associated with immune deviation in CD8 T cells in renal cell carcinoma patients. J Biomed Biotechnol (2010) 0.81
The transcriptional repressor gene Mad3 is a novel target for regulation by E2F1. Biochem J (2003) 0.80
Tumor dormancy: potential therapeutic target in tumor recurrence and metastasis prevention. Exp Hematol Oncol (2013) 0.79
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Novel functions for the transcription factor E2F4 in development and disease. Cell Cycle (2016) 0.76
E2f4 and E2f5 are essential for the development of the male reproductive system. Cell Cycle (2016) 0.76
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In silico pathway analysis in cervical carcinoma reveals potential new targets for treatment. Oncotarget (2016) 0.75
Meta-analysis reveals conserved cell cycle transcriptional network across multiple human cell types. BMC Genomics (2017) 0.75
Genome-wide analysis of shoot growth-associated alternative splicing in moso bamboo. Mol Genet Genomics (2016) 0.75
The DREAM complex through its subunit Lin37 cooperates with Rb to initiate quiescence. Elife (2017) 0.75
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