Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Hypothalamic mTOR signaling regulates food intake.
|
Science
|
2006
|
8.62
|
2
|
High-fructose, medium chain trans fat diet induces liver fibrosis and elevates plasma coenzyme Q9 in a novel murine model of obesity and nonalcoholic steatohepatitis.
|
Hepatology
|
2010
|
4.11
|
3
|
The central melanocortin system directly controls peripheral lipid metabolism.
|
J Clin Invest
|
2007
|
2.97
|
4
|
Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet.
|
Am J Physiol Endocrinol Metab
|
2008
|
2.86
|
5
|
Cloned mice have an obese phenotype not transmitted to their offspring.
|
Nat Med
|
2002
|
2.68
|
6
|
Gonadal hormones determine sensitivity to central leptin and insulin.
|
Diabetes
|
2006
|
2.62
|
7
|
Weight-independent changes in blood glucose homeostasis after gastric bypass or vertical sleeve gastrectomy in rats.
|
Gastroenterology
|
2011
|
2.45
|
8
|
Effects of a fixed meal pattern on ghrelin secretion: evidence for a learned response independent of nutrient status.
|
Endocrinology
|
2005
|
2.43
|
9
|
A surgical model in male obese rats uncovers protective effects of bile acids post-bariatric surgery.
|
Endocrinology
|
2013
|
2.39
|
10
|
Glucagon-like peptide-1 (GLP-1) receptors expressed on nerve terminals in the portal vein mediate the effects of endogenous GLP-1 on glucose tolerance in rats.
|
Endocrinology
|
2007
|
2.37
|
11
|
A role for central nervous system PPAR-γ in the regulation of energy balance.
|
Nat Med
|
2011
|
2.34
|
12
|
Arcuate glucagon-like peptide 1 receptors regulate glucose homeostasis but not food intake.
|
Diabetes
|
2008
|
2.33
|
13
|
Weight loss through ileal transposition is accompanied by increased ileal hormone secretion and synthesis in rats.
|
Am J Physiol Endocrinol Metab
|
2004
|
2.21
|
14
|
Is the energy homeostasis system inherently biased toward weight gain?
|
Diabetes
|
2003
|
2.14
|
15
|
Gastrointestinal hormones and food intake.
|
Gastroenterology
|
2005
|
2.00
|
16
|
The catabolic action of insulin in the brain is mediated by melanocortins.
|
J Neurosci
|
2002
|
1.95
|
17
|
Differential sensitivity to central leptin and insulin in male and female rats.
|
Diabetes
|
2003
|
1.80
|
18
|
Sleeve gastrectomy induces loss of weight and fat mass in obese rats, but does not affect leptin sensitivity.
|
Gastroenterology
|
2010
|
1.80
|
19
|
A new glucagon and GLP-1 co-agonist eliminates obesity in rodents.
|
Nat Chem Biol
|
2009
|
1.79
|
20
|
The role of hypothalamic mammalian target of rapamycin complex 1 signaling in diet-induced obesity.
|
J Neurosci
|
2008
|
1.71
|
21
|
Sleeve gastrectomy in rats improves postprandial lipid clearance by reducing intestinal triglyceride secretion.
|
Gastroenterology
|
2011
|
1.64
|
22
|
Estradiol-dependent decrease in the orexigenic potency of ghrelin in female rats.
|
Diabetes
|
2007
|
1.62
|
23
|
Insulin and leptin as adiposity signals.
|
Recent Prog Horm Res
|
2004
|
1.60
|
24
|
Cooperation between brain and islet in glucose homeostasis and diabetes.
|
Nature
|
2013
|
1.59
|
25
|
Monitoring of stored and available fuel by the CNS: implications for obesity.
|
Nat Rev Neurosci
|
2003
|
1.55
|
26
|
Improved rodent maternal metabolism but reduced intrauterine growth after vertical sleeve gastrectomy.
|
Sci Transl Med
|
2013
|
1.54
|
27
|
Direct control of peripheral lipid deposition by CNS GLP-1 receptor signaling is mediated by the sympathetic nervous system and blunted in diet-induced obesity.
|
J Neurosci
|
2009
|
1.54
|
28
|
Hyperphagia and increased fat accumulation in two models of chronic CNS glucagon-like peptide-1 loss of function.
|
J Neurosci
|
2011
|
1.54
|
29
|
Intestinal adaptation after ileal interposition surgery increases bile acid recycling and protects against obesity-related comorbidities.
|
Am J Physiol Gastrointest Liver Physiol
|
2010
|
1.54
|
30
|
Reduced anorexic effects of insulin in obesity-prone rats fed a moderate-fat diet.
|
Am J Physiol Regul Integr Comp Physiol
|
2004
|
1.49
|
31
|
Peripheral, but not central, CB1 antagonism provides food intake-independent metabolic benefits in diet-induced obese rats.
|
Diabetes
|
2008
|
1.39
|
32
|
Perinatal exposure to bisphenol-a and the development of metabolic syndrome in CD-1 mice.
|
Endocrinology
|
2010
|
1.38
|
33
|
Pleasurable behaviors reduce stress via brain reward pathways.
|
Proc Natl Acad Sci U S A
|
2010
|
1.33
|
34
|
Fasting and postprandial concentrations of GLP-1 in intestinal lymph and portal plasma: evidence for selective release of GLP-1 in the lymph system.
|
Am J Physiol Regul Integr Comp Physiol
|
2007
|
1.27
|
35
|
The timing of meals.
|
Psychol Rev
|
2004
|
1.26
|
36
|
The role of GM-CSF in adipose tissue inflammation.
|
Am J Physiol Endocrinol Metab
|
2008
|
1.26
|
37
|
Melanocortin signaling in the CNS directly regulates circulating cholesterol.
|
Nat Neurosci
|
2010
|
1.25
|
38
|
The renin angiotensin system and the metabolic syndrome.
|
Physiol Behav
|
2010
|
1.25
|
39
|
Dynamic body weight and body composition changes in response to subordination stress.
|
Physiol Behav
|
2007
|
1.24
|
40
|
Mechanisms of oleoylethanolamide-induced changes in feeding behavior and motor activity.
|
Am J Physiol Regul Integr Comp Physiol
|
2005
|
1.23
|
41
|
Central nervous system mechanisms linking the consumption of palatable high-fat diets to the defense of greater adiposity.
|
Cell Metab
|
2012
|
1.23
|
42
|
Assessment of feeding behavior in laboratory mice.
|
Cell Metab
|
2010
|
1.22
|
43
|
Eating elicited by orexin-a, but not melanin-concentrating hormone, is opioid mediated.
|
Endocrinology
|
2002
|
1.22
|
44
|
Intraventricular insulin and leptin reduce food intake and body weight in C57BL/6J mice.
|
Physiol Behav
|
2006
|
1.21
|
45
|
Fibroblast growth factor 21 mediates specific glucagon actions.
|
Diabetes
|
2013
|
1.20
|
46
|
Sexually different actions of leptin in proopiomelanocortin neurons to regulate glucose homeostasis.
|
Am J Physiol Endocrinol Metab
|
2008
|
1.20
|
47
|
Insulin and leptin combine additively to reduce food intake and body weight in rats.
|
Endocrinology
|
2002
|
1.18
|
48
|
Social stress and recovery: implications for body weight and body composition.
|
Am J Physiol Regul Integr Comp Physiol
|
2007
|
1.16
|
49
|
Similar effects of roux-en-Y gastric bypass and vertical sleeve gastrectomy on glucose regulation in rats.
|
Physiol Behav
|
2011
|
1.15
|
50
|
Antiobesity and antihyperglycemic effects of ginsenoside Rb1 in rats.
|
Diabetes
|
2010
|
1.15
|
51
|
Fibroblast growth factor-19 action in the brain reduces food intake and body weight and improves glucose tolerance in male rats.
|
Endocrinology
|
2012
|
1.15
|
52
|
Metabolic and endocrine consequences of social stress in a visible burrow system.
|
Physiol Behav
|
2004
|
1.14
|
53
|
Expression of new loci associated with obesity in diet-induced obese rats: from genetics to physiology.
|
Obesity (Silver Spring)
|
2011
|
1.12
|
54
|
Mice lacking the syndecan-3 gene are resistant to diet-induced obesity.
|
J Clin Invest
|
2004
|
1.11
|
55
|
Differences in the central anorectic effects of glucagon-like peptide-1 and exendin-4 in rats.
|
Diabetes
|
2009
|
1.10
|
56
|
Small molecule insulin mimetics reduce food intake and body weight and prevent development of obesity.
|
Nat Med
|
2002
|
1.09
|
57
|
Characterization of mice lacking the gene for cholecystokinin.
|
Am J Physiol Regul Integr Comp Physiol
|
2007
|
1.09
|
58
|
Meal-anticipatory glucagon-like peptide-1 secretion in rats.
|
Endocrinology
|
2009
|
1.08
|
59
|
The effect of fat removal on glucose tolerance is depot specific in male and female mice.
|
Am J Physiol Endocrinol Metab
|
2007
|
1.08
|
60
|
Apolipoprotein A-IV improves glucose homeostasis by enhancing insulin secretion.
|
Proc Natl Acad Sci U S A
|
2012
|
1.08
|
61
|
Consumption of a high-fat diet induces central insulin resistance independent of adiposity.
|
Physiol Behav
|
2011
|
1.07
|
62
|
Acute exposure to a high-fat diet alters meal patterns and body composition.
|
Physiol Behav
|
2010
|
1.07
|
63
|
Acute third ventricular administration of insulin decreases food intake in two paradigms.
|
Pharmacol Biochem Behav
|
2002
|
1.07
|
64
|
Overview of animal models of obesity.
|
Curr Protoc Pharmacol
|
2012
|
1.06
|
65
|
Roux-en-Y gastric bypass surgery but not vertical sleeve gastrectomy decreases bone mass in male rats.
|
Endocrinology
|
2013
|
1.05
|
66
|
Food intake-independent effects of CB1 antagonism on glucose and lipid metabolism.
|
Obesity (Silver Spring)
|
2009
|
1.04
|
67
|
The regulation of the lymphatic secretion of glucagon-like peptide-1 (GLP-1) by intestinal absorption of fat and carbohydrate.
|
Am J Physiol Gastrointest Liver Physiol
|
2007
|
1.04
|
68
|
Ghrelin enhances olfactory sensitivity and exploratory sniffing in rodents and humans.
|
J Neurosci
|
2011
|
1.04
|
69
|
Effect of vertical sleeve gastrectomy on food selection and satiation in rats.
|
Am J Physiol Endocrinol Metab
|
2012
|
1.04
|
70
|
Sexually dimorphic responses to fat loss after caloric restriction or surgical lipectomy.
|
Am J Physiol Endocrinol Metab
|
2007
|
1.03
|
71
|
High-fat-diet exposure induces IgG accumulation in hypothalamic microglia.
|
Dis Model Mech
|
2012
|
1.03
|
72
|
The endocrinology of food intake.
|
Nat Rev Endocrinol
|
2013
|
1.03
|
73
|
Exercise protects against high-fat diet-induced hypothalamic inflammation.
|
Physiol Behav
|
2012
|
1.03
|
74
|
Expression of biologically active rat apolipoprotein AIV in Escherichia coli.
|
Physiol Behav
|
2003
|
1.02
|
75
|
Angiotensin type 1 receptors in the subfornical organ mediate the drinking and hypothalamic-pituitary-adrenal response to systemic isoproterenol.
|
Endocrinology
|
2008
|
1.02
|
76
|
CNS leptin action modulates immune response and survival in sepsis.
|
J Neurosci
|
2010
|
1.01
|
77
|
High calorie diet triggers hypothalamic angiopathy.
|
Mol Metab
|
2012
|
1.01
|
78
|
Ginsenoside Rb1 reduces fatty liver by activating AMP-activated protein kinase in obese rats.
|
J Lipid Res
|
2013
|
1.01
|
79
|
Diurnal rhythm of apolipoprotein A-IV in rat hypothalamus and its relation to food intake and corticosterone.
|
Endocrinology
|
2004
|
1.00
|
80
|
Peptide designed to elicit apoptosis in adipose tissue endothelium reduces food intake and body weight.
|
Diabetes
|
2010
|
1.00
|
81
|
Hypothalamic apolipoprotein A-IV is regulated by leptin.
|
Endocrinology
|
2007
|
1.00
|
82
|
Using the lymph fistula rat model to study the potentiation of GIP secretion by the ingestion of fat and glucose.
|
Am J Physiol Gastrointest Liver Physiol
|
2008
|
1.00
|
83
|
Characterization of apolipoprotein A-IV in brain areas involved in energy homeostasis.
|
Physiol Behav
|
2008
|
0.98
|
84
|
Central angiotensin II has catabolic action at white and brown adipose tissue.
|
Am J Physiol Endocrinol Metab
|
2011
|
0.98
|
85
|
Angiotensin type 1a receptors in the paraventricular nucleus of the hypothalamus protect against diet-induced obesity.
|
J Neurosci
|
2013
|
0.97
|
86
|
Pharmaceutical approaches to the treatment of obesity.
|
Drug Discov Today
|
2004
|
0.97
|
87
|
Central administration of melanin-concentrating hormone increases alcohol and sucrose/quinine intake in rats.
|
Alcohol Clin Exp Res
|
2005
|
0.97
|
88
|
The central insulin system and energy balance.
|
Handb Exp Pharmacol
|
2012
|
0.97
|
89
|
Brain apolipoprotein E: an important regulator of food intake in rats.
|
Diabetes
|
2008
|
0.97
|
90
|
Ghrelin-induced adiposity is independent of orexigenic effects.
|
FASEB J
|
2011
|
0.97
|
91
|
Regulation of energy homeostasis and health consequences in obesity.
|
Am J Med
|
2009
|
0.97
|
92
|
Structure of human apolipoprotein A-IV: a distinct domain architecture among exchangeable apolipoproteins with potential functional implications.
|
Biochemistry
|
2004
|
0.96
|
93
|
Glucose parameters are altered in mouse offspring produced by assisted reproductive technologies and somatic cell nuclear transfer.
|
Biol Reprod
|
2010
|
0.96
|
94
|
The effect of angiotensin-converting enzyme inhibition using captopril on energy balance and glucose homeostasis.
|
Endocrinology
|
2009
|
0.95
|
95
|
Blood-borne angiotensin II acts in the brain to influence behavioral and endocrine responses to psychogenic stress.
|
J Neurosci
|
2011
|
0.95
|
96
|
Effect of vertical sleeve gastrectomy in melanocortin receptor 4-deficient rats.
|
Am J Physiol Endocrinol Metab
|
2012
|
0.95
|
97
|
Increased dietary fat attenuates the anorexic effects of intracerebroventricular injections of MTII.
|
Endocrinology
|
2003
|
0.95
|
98
|
Interaction of apolipoprotein AIV with cholecystokinin on the control of food intake.
|
Am J Physiol Regul Integr Comp Physiol
|
2007
|
0.94
|
99
|
Individual differences in initial sensitivity and acute tolerance predict patterns of chronic drug tolerance to nitrous-oxide-induced hypothermia in rats.
|
Psychopharmacology (Berl)
|
2005
|
0.93
|
100
|
The role of previous exposure in the appetitive and consummatory effects of orexigenic neuropeptides.
|
Peptides
|
2005
|
0.93
|
101
|
Meal patterns and hypothalamic NPY expression during chronic social stress and recovery.
|
Am J Physiol Regul Integr Comp Physiol
|
2010
|
0.93
|
102
|
Fatty acid synthase inhibitors modulate energy balance via mammalian target of rapamycin complex 1 signaling in the central nervous system.
|
Diabetes
|
2008
|
0.92
|
103
|
Regulation of gastric emptying rate and its role in nutrient-induced GLP-1 secretion in rats after vertical sleeve gastrectomy.
|
Am J Physiol Endocrinol Metab
|
2013
|
0.92
|
104
|
Hydration state controls stress responsiveness and social behavior.
|
J Neurosci
|
2011
|
0.91
|
105
|
Intraventricular melanin-concentrating hormone stimulates water intake independent of food intake.
|
Am J Physiol Regul Integr Comp Physiol
|
2003
|
0.90
|
106
|
The orphan receptor Gpr83 regulates systemic energy metabolism via ghrelin-dependent and ghrelin-independent mechanisms.
|
Nat Commun
|
2013
|
0.90
|
107
|
Central amylin acts as an adiposity signal to control body weight and energy expenditure.
|
Physiol Behav
|
2010
|
0.89
|
108
|
Cholecystokinin knockout mice are resistant to high-fat diet-induced obesity.
|
Gastroenterology
|
2010
|
0.89
|
109
|
Minireview: Endocannabinoids and their receptors as targets for obesity therapy.
|
Endocrinology
|
2009
|
0.89
|
110
|
Transplantation or removal of intra-abdominal adipose tissue prevents age-induced glucose insensitivity.
|
Physiol Behav
|
2010
|
0.89
|
111
|
Adrenalectomy alters the sensitivity of the central nervous system melanocortin system.
|
Diabetes
|
2003
|
0.89
|
112
|
C75 inhibits food intake by increasing CNS glucose metabolism.
|
Nat Med
|
2003
|
0.89
|
113
|
Reversal of diet-induced obesity increases insulin transport into cerebrospinal fluid and restores sensitivity to the anorexic action of central insulin in male rats.
|
Endocrinology
|
2013
|
0.88
|
114
|
Acylation type determines ghrelin's effects on energy homeostasis in rodents.
|
Endocrinology
|
2012
|
0.88
|
115
|
The brain is getting ready for dinner.
|
Cell Metab
|
2006
|
0.88
|
116
|
Obesity induced by a high-fat diet downregulates apolipoprotein A-IV gene expression in rat hypothalamus.
|
Am J Physiol Endocrinol Metab
|
2004
|
0.88
|
117
|
The roles of leptin receptors on POMC neurons in the regulation of sex-specific energy homeostasis.
|
Physiol Behav
|
2010
|
0.88
|
118
|
Apolipoprotein E does not cross the blood-cerebrospinal fluid barrier, as revealed by an improved technique for sampling CSF from mice.
|
Am J Physiol Regul Integr Comp Physiol
|
2012
|
0.87
|
119
|
Apolipoprotein A-IV interacts synergistically with melanocortins to reduce food intake.
|
Am J Physiol Regul Integr Comp Physiol
|
2005
|
0.87
|
120
|
The role of neuropeptide Y in energy homeostasis.
|
Handb Exp Pharmacol
|
2012
|
0.87
|
121
|
Apolipoprotein AIV requires cholecystokinin and vagal nerves to suppress food intake.
|
Endocrinology
|
2012
|
0.87
|
122
|
Rapid and weight-independent improvement of glucose tolerance induced by a peptide designed to elicit apoptosis in adipose tissue endothelium.
|
Diabetes
|
2012
|
0.87
|
123
|
High-fat diet changes the temporal profile of GLP-1 receptor-mediated hypophagia in rats.
|
Am J Physiol Regul Integr Comp Physiol
|
2013
|
0.86
|
124
|
Caloric restriction chronically impairs metabolic programming in mice.
|
Diabetes
|
2012
|
0.86
|
125
|
Differential effects of glucocorticoids on energy homeostasis in Syrian hamsters.
|
Am J Physiol Endocrinol Metab
|
2011
|
0.85
|
126
|
The impact of moderate daily alcohol consumption on aggression and the formation of dominance hierarchies in rats.
|
Psychopharmacology (Berl)
|
2006
|
0.85
|
127
|
Suppression of food intake by glucagon-like peptide-1 receptor agonists: relative potencies and role of dipeptidyl peptidase-4.
|
Endocrinology
|
2012
|
0.85
|
128
|
Attenuated feeding responses to circadian and palatability cues in mice lacking neuropeptide Y.
|
Peptides
|
2005
|
0.85
|
129
|
Phenotype of cloned mice: development, behavior, and physiology.
|
Exp Biol Med (Maywood)
|
2003
|
0.85
|
130
|
The anorectic effect of GLP-1 in rats is nutrient dependent.
|
PLoS One
|
2012
|
0.85
|
131
|
Nitrous oxide analgesia in humans: acute and chronic tolerance.
|
Pain
|
2005
|
0.84
|
132
|
Estradiol increases the anorectic effect of central apolipoprotein A-IV.
|
Endocrinology
|
2010
|
0.84
|
133
|
Insulin increases central apolipoprotein E levels as revealed by an improved technique for collection of cerebrospinal fluid from rats.
|
J Neurosci Methods
|
2012
|
0.84
|
134
|
Learned meal initiation attenuates the anorexic effects of the melanocortin agonist MTII.
|
Diabetes
|
2003
|
0.84
|
135
|
High-fat diet induced adiposity in mice with targeted disruption of the dopamine-3 receptor gene.
|
Behav Brain Res
|
2004
|
0.84
|
136
|
Oral L-arginine stimulates GLP-1 secretion to improve glucose tolerance in male mice.
|
Endocrinology
|
2013
|
0.83
|
137
|
Up-regulation of apolipoprotein E by leptin in the hypothalamus of mice and rats.
|
Physiol Behav
|
2009
|
0.83
|
138
|
Impaired insulin secretion and enhanced insulin sensitivity in cholecystokinin-deficient mice.
|
Diabetes
|
2011
|
0.83
|
139
|
Effect of intraperitoneal and intravenous administration of cholecystokinin-8 and apolipoprotein AIV on intestinal lymphatic CCK-8 and apo AIV concentration.
|
Am J Physiol Regul Integr Comp Physiol
|
2008
|
0.83
|
140
|
Interactions between the central nervous system and pancreatic islet secretions: a historical perspective.
|
Adv Physiol Educ
|
2013
|
0.83
|
141
|
Ethanol consumption in mice with a targeted disruption of the dopamine-3 receptor gene.
|
Addict Biol
|
2003
|
0.82
|
142
|
CNS opioid signaling separates cannabinoid receptor 1-mediated effects on body weight and mood-related behavior in mice.
|
Endocrinology
|
2011
|
0.82
|
143
|
Mechanism of the induction of brain c-Fos-positive neurons by lipid absorption.
|
Am J Physiol Regul Integr Comp Physiol
|
2006
|
0.82
|
144
|
Neuropeptide Y and lipid increase apolipoprotein AIV gene expression in rat hypothalamus.
|
Brain Res
|
2003
|
0.82
|
145
|
Effect of peripheral administration of cholecystokinin on food intake in apolipoprotein AIV knockout mice.
|
Am J Physiol Gastrointest Liver Physiol
|
2012
|
0.82
|
146
|
Alcohol drinking in MCH receptor-1-deficient mice.
|
Alcohol Clin Exp Res
|
2007
|
0.81
|
147
|
Two novel paradigms for the simultaneous assessment of conditioned taste aversion and food intake effects of anorexic agents.
|
Physiol Behav
|
2003
|
0.81
|
148
|
Apolipoprotein E reduces food intake via PI3K/Akt signaling pathway in the hypothalamus.
|
Physiol Behav
|
2011
|
0.81
|
149
|
7-OH-DPAT selectively reduces intake of both chow and high fat diets in different food intake regimens.
|
Pharmacol Biochem Behav
|
2003
|
0.81
|
150
|
Acute 3rd-ventricular amylin infusion potently reduces food intake but does not produce aversive consequences.
|
Peptides
|
2002
|
0.80
|
151
|
Differential effects of adrenalectomy on melanin-concentrating hormone and orexin A.
|
Endocrinology
|
2004
|
0.80
|
152
|
Physiological responses to acute psychological stress are reduced by the PPARγ agonist rosiglitazone.
|
Endocrinology
|
2012
|
0.80
|
153
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Food-entrained rhythmic expression of apolipoprotein E expression in the hypothalamus of rats.
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