Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo.

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Published in Proc Natl Acad Sci U S A on March 12, 2003

Authors

Wesley Farris1, Stefan Mansourian, Yang Chang, Loren Lindsley, Elizabeth A Eckman, Matthew P Frosch, Christopher B Eckman, Rudolph E Tanzi, Dennis J Selkoe, Suzanne Guenette

Author Affiliations

1: Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Boston, MA 02115, USA.

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