Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Identification of RIP1 kinase as a specific cellular target of necrostatins.
|
Nat Chem Biol
|
2008
|
9.24
|
2
|
Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix.
|
Science
|
2004
|
7.63
|
3
|
Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis.
|
Nat Genet
|
2011
|
6.89
|
4
|
Evidence for an alternative glycolytic pathway in rapidly proliferating cells.
|
Science
|
2010
|
5.44
|
5
|
Functional characterization of IRESes by an inhibitor of the RNA helicase eIF4A.
|
Nat Chem Biol
|
2006
|
3.89
|
6
|
Ribosome loading onto the mRNA cap is driven by conformational coupling between eIF4G and eIF4E.
|
Cell
|
2003
|
3.46
|
7
|
Solution structure of the integral human membrane protein VDAC-1 in detergent micelles.
|
Science
|
2008
|
3.38
|
8
|
The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptor.
|
Cell
|
2003
|
3.36
|
9
|
Structural basis for recruitment of CBP/p300 by hypoxia-inducible factor-1 alpha.
|
Proc Natl Acad Sci U S A
|
2002
|
3.28
|
10
|
An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis.
|
Nature
|
2006
|
3.23
|
11
|
Small-molecule inhibition of the interaction between the translation initiation factors eIF4E and eIF4G.
|
Cell
|
2007
|
3.21
|
12
|
HIV-1 broadly neutralizing antibody extracts its epitope from a kinked gp41 ectodomain region on the viral membrane.
|
Immunity
|
2008
|
3.01
|
13
|
A nuclear receptor-like pathway regulating multidrug resistance in fungi.
|
Nature
|
2008
|
3.00
|
14
|
Metabolic regulation of protein N-alpha-acetylation by Bcl-xL promotes cell survival.
|
Cell
|
2011
|
2.98
|
15
|
Position of eukaryotic initiation factor eIF1 on the 40S ribosomal subunit determined by directed hydroxyl radical probing.
|
Genes Dev
|
2003
|
2.77
|
16
|
Topology and regulation of the human eIF4A/4G/4H helicase complex in translation initiation.
|
Cell
|
2009
|
2.60
|
17
|
The rhesus rotavirus VP4 sialic acid binding domain has a galectin fold with a novel carbohydrate binding site.
|
EMBO J
|
2002
|
2.41
|
18
|
The alphabeta T cell receptor is an anisotropic mechanosensor.
|
J Biol Chem
|
2009
|
2.41
|
19
|
Ultrahigh-resolution (1)H-(13)C HSQC spectra of metabolite mixtures using nonlinear sampling and forward maximum entropy reconstruction.
|
J Am Chem Soc
|
2007
|
2.40
|
20
|
Dynamic thiolation-thioesterase structure of a non-ribosomal peptide synthetase.
|
Nature
|
2008
|
2.39
|
21
|
The mRNA cap-binding protein eIF4E in post-transcriptional gene expression.
|
Nat Struct Mol Biol
|
2004
|
2.37
|
22
|
Translation initiation: structures, mechanisms and evolution.
|
Q Rev Biophys
|
2005
|
2.31
|
23
|
Accelerated acquisition of high resolution triple-resonance spectra using non-uniform sampling and maximum entropy reconstruction.
|
J Magn Reson
|
2004
|
2.30
|
24
|
Structural studies of the interaction between ubiquitin family proteins and proteasome subunit S5a.
|
Biochemistry
|
2002
|
2.29
|
25
|
Structural basis for negative regulation of hypoxia-inducible factor-1alpha by CITED2.
|
Nat Struct Biol
|
2003
|
2.23
|
26
|
In situ observation of protein phosphorylation by high-resolution NMR spectroscopy.
|
Nat Struct Mol Biol
|
2008
|
2.23
|
27
|
A general framework for development and data analysis of competitive high-throughput screens for small-molecule inhibitors of protein-protein interactions by fluorescence polarization.
|
Biochemistry
|
2004
|
2.20
|
28
|
Solution structure of the HIV-1 integrase-binding domain in LEDGF/p75.
|
Nat Struct Mol Biol
|
2005
|
2.17
|
29
|
Mammalian SCAN domain dimer is a domain-swapped homolog of the HIV capsid C-terminal domain.
|
Mol Cell
|
2005
|
2.07
|
30
|
Optimized phospholipid bilayer nanodiscs facilitate high-resolution structure determination of membrane proteins.
|
J Am Chem Soc
|
2013
|
1.90
|
31
|
Ufd1 exhibits the AAA-ATPase fold with two distinct ubiquitin interaction sites.
|
Structure
|
2005
|
1.86
|
32
|
Structural basis for the enhancement of eIF4A helicase activity by eIF4G.
|
Genes Dev
|
2005
|
1.83
|
33
|
Application of iterative soft thresholding for fast reconstruction of NMR data non-uniformly sampled with multidimensional Poisson Gap scheduling.
|
J Biomol NMR
|
2012
|
1.81
|
34
|
Broadly neutralizing anti-HIV-1 antibodies disrupt a hinge-related function of gp41 at the membrane interface.
|
Proc Natl Acad Sci U S A
|
2009
|
1.79
|
35
|
Poisson-gap sampling and forward maximum entropy reconstruction for enhancing the resolution and sensitivity of protein NMR data.
|
J Am Chem Soc
|
2010
|
1.78
|
36
|
NMR structural investigation of the mitochondrial outer membrane protein VDAC and its interaction with antiapoptotic Bcl-xL.
|
Biochemistry
|
2007
|
1.76
|
37
|
Scleraxis and NFATc regulate the expression of the pro-alpha1(I) collagen gene in tendon fibroblasts.
|
J Biol Chem
|
2007
|
1.72
|
38
|
RNA-mediated sequestration of the RNA helicase eIF4A by Pateamine A inhibits translation initiation.
|
Chem Biol
|
2006
|
1.71
|
39
|
Quantitative NMR analysis of the protein G B1 domain in Xenopus laevis egg extracts and intact oocytes.
|
Proc Natl Acad Sci U S A
|
2006
|
1.70
|
40
|
Structural basis for the selectivity of the external thioesterase of the surfactin synthetase.
|
Nature
|
2008
|
1.66
|
41
|
Domain-swapped dimerization of the HIV-1 capsid C-terminal domain.
|
Proc Natl Acad Sci U S A
|
2007
|
1.66
|
42
|
Modular architecture of the bacteriophage T7 primase couples RNA primer synthesis to DNA synthesis.
|
Mol Cell
|
2003
|
1.61
|
43
|
Small molecule inhibition of phosphatidylinositol-3,4,5-triphosphate (PIP3) binding to pleckstrin homology domains.
|
Proc Natl Acad Sci U S A
|
2010
|
1.61
|
44
|
Position of eukaryotic translation initiation factor eIF1A on the 40S ribosomal subunit mapped by directed hydroxyl radical probing.
|
Nucleic Acids Res
|
2009
|
1.61
|
45
|
Structural and functional characterization of the integral membrane protein VDAC-1 in lipid bilayer nanodiscs.
|
J Am Chem Soc
|
2009
|
1.55
|
46
|
The kinetochore-bound Ska1 complex tracks depolymerizing microtubules and binds to curved protofilaments.
|
Dev Cell
|
2012
|
1.54
|
47
|
PDCD4 inhibits translation initiation by binding to eIF4A using both its MA3 domains.
|
Proc Natl Acad Sci U S A
|
2008
|
1.52
|
48
|
FM reconstruction of non-uniformly sampled protein NMR data at higher dimensions and optimization by distillation.
|
J Biomol NMR
|
2009
|
1.52
|
49
|
Selective pharmacological targeting of a DEAD box RNA helicase.
|
PLoS One
|
2008
|
1.49
|
50
|
Solution structure of human initiation factor eIF2alpha reveals homology to the elongation factor eEF1B.
|
Structure
|
2004
|
1.48
|
51
|
Non-uniformly sampled double-TROSY hNcaNH experiments for NMR sequential assignments of large proteins.
|
J Am Chem Soc
|
2006
|
1.45
|
52
|
Mapping the binding interface between human eukaryotic initiation factors 1A and 5B: a new interaction between old partners.
|
Proc Natl Acad Sci U S A
|
2003
|
1.41
|
53
|
Solution NMR structure determination of proteins revisited.
|
J Biomol NMR
|
2008
|
1.39
|
54
|
Is routine hysteroscopy during LLETZ a valuable additional procedure?
|
Acta Obstet Gynecol Scand
|
2011
|
1.39
|
55
|
Alternate 13C-12C labeling for complete mainchain resonance assignments using C alpha direct-detection with applicability toward fast relaxing protein systems.
|
J Am Chem Soc
|
2008
|
1.39
|
56
|
Selective inhibition of calcineurin-NFAT signaling by blocking protein-protein interaction with small organic molecules.
|
Proc Natl Acad Sci U S A
|
2004
|
1.37
|
57
|
Applications of non-uniform sampling and processing.
|
Top Curr Chem
|
2012
|
1.37
|
58
|
Eukaryotic initiation factor (eIF) 1 carries two distinct eIF5-binding faces important for multifactor assembly and AUG selection.
|
J Biol Chem
|
2007
|
1.34
|
59
|
The eukaryotic initiation factor (eIF) 5 HEAT domain mediates multifactor assembly and scanning with distinct interfaces to eIF1, eIF2, eIF3, and eIF4G.
|
Proc Natl Acad Sci U S A
|
2005
|
1.34
|
60
|
Solution structure of the CD3epsilondelta ectodomain and comparison with CD3epsilongamma as a basis for modeling T cell receptor topology and signaling.
|
Proc Natl Acad Sci U S A
|
2004
|
1.33
|
61
|
Coupled decomposition of four-dimensional NOESY spectra.
|
J Am Chem Soc
|
2009
|
1.31
|
62
|
Position of eukaryotic initiation factor eIF5B on the 80S ribosome mapped by directed hydroxyl radical probing.
|
EMBO J
|
2007
|
1.31
|
63
|
A PHD finger motif in the C terminus of RAG2 modulates recombination activity.
|
J Biol Chem
|
2005
|
1.31
|
64
|
Antibody mechanics on a membrane-bound HIV segment essential for GP41-targeted viral neutralization.
|
Nat Struct Mol Biol
|
2011
|
1.29
|
65
|
Exploring signal-to-noise ratio and sensitivity in non-uniformly sampled multi-dimensional NMR spectra.
|
J Biomol NMR
|
2012
|
1.29
|
66
|
eIF4G and CBP80 share a common origin and similar domain organization: implications for the structure and function of eIF4G.
|
Biochemistry
|
2005
|
1.26
|
67
|
Nonmicellar systems for solution NMR spectroscopy of membrane proteins.
|
Curr Opin Struct Biol
|
2010
|
1.24
|
68
|
IBIS--a tool for automated sequential assignment of protein spectra from triple resonance experiments.
|
J Biomol NMR
|
2003
|
1.24
|
69
|
Structural basis for the recruitment of ERCC1-XPF to nucleotide excision repair complexes by XPA.
|
EMBO J
|
2007
|
1.23
|
70
|
Using codon optimization, chaperone co-expression, and rational mutagenesis for production and NMR assignments of human eIF2 alpha.
|
J Biomol NMR
|
2004
|
1.23
|
71
|
Fast assignment of 15N-HSQC peaks using high-resolution 3D HNcocaNH experiments with non-uniform sampling.
|
J Biomol NMR
|
2005
|
1.22
|
72
|
Inhibition of the interactions between eukaryotic initiation factors 4E and 4G impairs long-term associative memory consolidation but not reconsolidation.
|
Proc Natl Acad Sci U S A
|
2011
|
1.22
|
73
|
Molecular framework for the activation of RNA-dependent protein kinase.
|
J Biol Chem
|
2007
|
1.21
|
74
|
A zinc clasp structure tethers Lck to T cell coreceptors CD4 and CD8.
|
Science
|
2003
|
1.21
|
75
|
Mediator subunit Gal11p/MED15 is required for fatty acid-dependent gene activation by yeast transcription factor Oaf1p.
|
J Biol Chem
|
2008
|
1.20
|
76
|
Cell-free expressed bacteriorhodopsin in different soluble membrane mimetics: biophysical properties and NMR accessibility.
|
Structure
|
2013
|
1.19
|
77
|
NMR methods for studying protein-protein interactions involved in translation initiation.
|
Methods Enzymol
|
2007
|
1.19
|
78
|
Tumor suppression by small molecule inhibitors of translation initiation.
|
Oncotarget
|
2012
|
1.17
|
79
|
Structure of the VP16 transactivator target in the Mediator.
|
Nat Struct Mol Biol
|
2011
|
1.17
|
80
|
NMR studies of protein interactions.
|
Curr Opin Struct Biol
|
2006
|
1.16
|
81
|
Investigating macromolecules inside cultured and injected cells by in-cell NMR spectroscopy.
|
Nat Protoc
|
2006
|
1.16
|
82
|
A sensitive and robust method for obtaining intermolecular NOEs between side chains in large protein complexes.
|
J Biomol NMR
|
2003
|
1.16
|
83
|
Overcoming the solubility limit with solubility-enhancement tags: successful applications in biomolecular NMR studies.
|
J Biomol NMR
|
2010
|
1.15
|
84
|
Looking into live cells with in-cell NMR spectroscopy.
|
J Struct Biol
|
2007
|
1.15
|
85
|
The C-terminal domain of eukaryotic initiation factor 5 promotes start codon recognition by its dynamic interplay with eIF1 and eIF2β.
|
Cell Rep
|
2012
|
1.13
|
86
|
The 3D structures of VDAC represent a native conformation.
|
Trends Biochem Sci
|
2010
|
1.13
|
87
|
Unambiguous assignment of NMR protein backbone signals with a time-shared triple-resonance experiment.
|
J Biomol NMR
|
2005
|
1.12
|
88
|
1-13C amino acid selective labeling in a 2H15N background for NMR studies of large proteins.
|
J Biomol NMR
|
2007
|
1.10
|
89
|
A molecular handoff between bacteriophage T7 DNA primase and T7 DNA polymerase initiates DNA synthesis.
|
J Biol Chem
|
2004
|
1.09
|
90
|
Broadband 13C-13C adiabatic mixing in solution optimized for high fields.
|
J Magn Reson
|
2003
|
1.07
|
91
|
Specificity and affinity of sialic acid binding by the rhesus rotavirus VP8* core.
|
J Virol
|
2002
|
1.06
|
92
|
Acidic C-terminal tail of the ssDNA-binding protein of bacteriophage T7 and ssDNA compete for the same binding surface.
|
Proc Natl Acad Sci U S A
|
2008
|
1.06
|
93
|
Mapping of the auto-inhibitory interactions of protein kinase R by nuclear magnetic resonance.
|
J Mol Biol
|
2006
|
1.04
|
94
|
Folding transitions during assembly of the eukaryotic mRNA cap-binding complex.
|
J Mol Biol
|
2005
|
1.04
|
95
|
A methylation-dependent electrostatic switch controls DNA repair and transcriptional activation by E. coli ada.
|
Mol Cell
|
2005
|
1.03
|
96
|
Distinctive CD3 heterodimeric ectodomain topologies maximize antigen-triggered activation of alpha beta T cell receptors.
|
J Immunol
|
2010
|
1.03
|
97
|
Determination of all nOes in 1H-13C-Me-ILV-U-2H-15N proteins with two time-shared experiments.
|
J Biomol NMR
|
2006
|
1.03
|
98
|
Structure of the calcineurin-NFAT complex: defining a T cell activation switch using solution NMR and crystal coordinates.
|
Structure
|
2007
|
1.02
|
99
|
CTL recognition of a protective immunodominant influenza A virus nucleoprotein epitope utilizes a highly restricted Vbeta but diverse Valpha repertoire: functional and structural implications.
|
J Mol Biol
|
2007
|
1.01
|
100
|
TCR Mechanobiology: Torques and Tunable Structures Linked to Early T Cell Signaling.
|
Front Immunol
|
2012
|
1.01
|
101
|
Solution NMR spectroscopic characterization of human VDAC-2 in detergent micelles and lipid bilayer nanodiscs.
|
Biochim Biophys Acta
|
2011
|
1.01
|
102
|
Structural and functional evidence that Nck interaction with CD3epsilon regulates T-cell receptor activity.
|
J Mol Biol
|
2008
|
1.00
|
103
|
The role of solution NMR in the structure determinations of VDAC-1 and other membrane proteins.
|
Curr Opin Struct Biol
|
2009
|
1.00
|
104
|
Respiratory and haemodynamic changes during decremental open lung positive end-expiratory pressure titration in patients with acute respiratory distress syndrome.
|
Crit Care
|
2009
|
0.99
|
105
|
TreeDock: a tool for protein docking based on minimizing van der Waals energies.
|
J Am Chem Soc
|
2002
|
0.96
|
106
|
Lipid dynamics and protein-lipid interactions in 2D crystals formed with the β-barrel integral membrane protein VDAC1.
|
J Am Chem Soc
|
2012
|
0.95
|
107
|
Optimal pulse design in quantum control: a unified computational method.
|
Proc Natl Acad Sci U S A
|
2011
|
0.95
|
108
|
High-resolution aliphatic side-chain assignments in 3D HCcoNH experiments with joint H-C evolution and non-uniform sampling.
|
J Biomol NMR
|
2005
|
0.94
|
109
|
Speeding up direct (15)N detection: hCaN 2D NMR experiment.
|
J Biomol NMR
|
2011
|
0.94
|
110
|
Solution structure of the first SRC homology 3 domain of human Nck2.
|
J Biomol NMR
|
2006
|
0.94
|
111
|
Ubiquitin family proteins and their relationship to the proteasome: a structural perspective.
|
Biochim Biophys Acta
|
2004
|
0.94
|
112
|
A novel approach for characterizing protein ligand complexes: molecular basis for specificity of small-molecule Bcl-2 inhibitors.
|
J Am Chem Soc
|
2002
|
0.94
|
113
|
Dynamic interaction of CD2 with the GYF and the SH3 domain of compartmentalized effector molecules.
|
EMBO J
|
2002
|
0.94
|
114
|
NMR solution structure and condition-dependent oligomerization of the antimicrobial peptide human defensin 5.
|
Biochemistry
|
2012
|
0.94
|
115
|
High-resolution 3D CANCA NMR experiments for complete mainchain assignments using C(alpha) direct detection.
|
J Am Chem Soc
|
2010
|
0.94
|
116
|
Immunogenicity of membrane-bound HIV-1 gp41 membrane-proximal external region (MPER) segments is dominated by residue accessibility and modulated by stereochemistry.
|
J Biol Chem
|
2013
|
0.93
|
117
|
β-Hairpin loop of eukaryotic initiation factor 1 (eIF1) mediates 40 S ribosome binding to regulate initiator tRNA(Met) recruitment and accuracy of AUG selection in vivo.
|
J Biol Chem
|
2013
|
0.93
|
118
|
Effects of redox potential and Ca2+ on the inositol 1,4,5-trisphosphate receptor L3-1 loop region: implications for receptor regulation.
|
J Biol Chem
|
2008
|
0.93
|
119
|
Evolutionary changes in the Leishmania eIF4F complex involve variations in the eIF4E-eIF4G interactions.
|
Nucleic Acids Res
|
2009
|
0.92
|
120
|
Enhanced eIF1 binding to the 40S ribosome impedes conformational rearrangements of the preinitiation complex and elevates initiation accuracy.
|
RNA
|
2013
|
0.92
|
121
|
NMR distinction of single- and multiple-mode binding of small-molecule protein ligands.
|
J Am Chem Soc
|
2006
|
0.92
|
122
|
The T-lock: automated compensation of radio-frequency induced sample heating.
|
J Biomol NMR
|
2009
|
0.91
|
123
|
Structural and functional analysis of human cytomegalovirus US3 protein.
|
J Virol
|
2004
|
0.91
|
124
|
Multiple conformations in the ligand-binding site of the yeast nuclear pore-targeting domain of Nup116p.
|
J Biol Chem
|
2005
|
0.91
|
125
|
Pulse design for broadband correlation NMR spectroscopy by multi-rotating frames.
|
J Biomol NMR
|
2013
|
0.91
|
126
|
Impact of macromolecular crowding on DNA replication.
|
Nat Commun
|
2013
|
0.90
|
127
|
A novel 4E-interacting protein in Leishmania is involved in stage-specific translation pathways.
|
Nucleic Acids Res
|
2011
|
0.90
|
128
|
Discovery of small-molecule inhibitors of the NFAT--calcineurin interaction by competitive high-throughput fluorescence polarization screening.
|
Biochemistry
|
2004
|
0.90
|
129
|
Hypoxia-inducible factor-1α (HIF-1α) promotes cap-dependent translation of selective mRNAs through up-regulating initiation factor eIF4E1 in breast cancer cells under hypoxia conditions.
|
J Biol Chem
|
2013
|
0.90
|
130
|
Correspondence between spin-dynamic phases and pulse program phases of NMR spectrometers.
|
J Magn Reson
|
2005
|
0.89
|
131
|
Intravenous leiomyomatosis of the uterus with pulmonary metastases or a case with benign metastasizing leiomyoma?
|
Anticancer Res
|
2009
|
0.89
|
132
|
Sensitivity enhancement in NMR of macromolecules by application of optimal control theory.
|
J Biomol NMR
|
2005
|
0.89
|
133
|
Multiple-quantum magic-angle spinning spectroscopy using nonlinear sampling.
|
J Magn Reson
|
2003
|
0.89
|
134
|
Importance of the CD3gamma ectodomain terminal beta-strand and membrane proximal stalk in thymic development and receptor assembly.
|
J Immunol
|
2007
|
0.89
|
135
|
NMR structure of the [2Fe-2S] ferredoxin domain from soluble methane monooxygenase reductase and interaction with its hydroxylase.
|
Biochemistry
|
2002
|
0.89
|
136
|
Molecular characterization of disrupted in schizophrenia-1 risk variant S704C reveals the formation of altered oligomeric assembly.
|
J Biol Chem
|
2011
|
0.89
|
137
|
CACA-TOCSY with alternate 13C-12C labeling: a 13Calpha direct detection experiment for mainchain resonance assignment, dihedral angle information, and amino acid type identification.
|
J Biomol NMR
|
2010
|
0.89
|
138
|
Fas apoptosis inhibitory molecule contains a novel beta-sandwich in contact with a partially ordered domain.
|
J Mol Biol
|
2009
|
0.88
|
139
|
A double TROSY hNCAnH experiment for efficient assignment of large and challenging proteins.
|
J Am Chem Soc
|
2009
|
0.88
|
140
|
Nitrogen-detected CAN and CON experiments as alternative experiments for main chain NMR resonance assignments.
|
J Biomol NMR
|
2010
|
0.88
|
141
|
The interaction between eukaryotic initiation factor 1A and eIF5 retains eIF1 within scanning preinitiation complexes.
|
Biochemistry
|
2013
|
0.86
|
142
|
Sequence and structure evolved separately in a ribosomal ubiquitin variant.
|
EMBO J
|
2007
|
0.86
|
143
|
Structural investigations of a GYF domain covalently linked to a proline-rich peptide.
|
J Biomol NMR
|
2003
|
0.85
|
144
|
Complexes of native ubiquitin and dodecyl sulfate illustrate the nature of hydrophobic and electrostatic interactions in the binding of proteins and surfactants.
|
J Am Chem Soc
|
2011
|
0.84
|
145
|
Selective methyl labeling of eukaryotic membrane proteins using cell-free expression.
|
J Am Chem Soc
|
2014
|
0.83
|
146
|
Backbone resonance assignment of the HEAT1-domain of the human eukaryotic translation initiation factor 4GI.
|
Biomol NMR Assign
|
2013
|
0.83
|
147
|
NMR mapping of protein interactions in living cells.
|
Nat Methods
|
2006
|
0.83
|
148
|
Discovery and characterization of a disulfide-locked C(2)-symmetric defensin peptide.
|
J Am Chem Soc
|
2014
|
0.83
|
149
|
Solid-state NMR structure determination from diagonal-compensated, sparsely nonuniform-sampled 4D proton-proton restraints.
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J Am Chem Soc
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NMR resonance assignments of the catalytic domain of human serine/threonine phosphatase calcineurin in unligated and PVIVIT-peptide-bound states.
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Backbone and ILV side chain methyl group assignments of the integral human membrane protein VDAC-1.
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Synthetic studies toward aryl-(4-aryl-4H-[1,2,4]triazole-3-yl)-amine from 1,3-diarylthiourea as urea mimetics.
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